Modulation of Pulmonary Microbiota by Antibiotic or Probiotic Aerosol Therapy: A Strategy to Promote Immunosurveillance against Lung Metastases

Cell Reports

Volumn 24, Issue 13, 2018, Pages 3528-3538

  Le Noci, Valentino ^a   Guglielmetti, Simone ^b   Arioli, Stefania ^b   Camisaschi, Chiara ^a   Bianchi, Francesca ^a,b   Sommariva, Michele ^b   Storti, Chiara ^b   Triulzi, Tiziana ^a   Castelli, Chiara ^a   Balsari, Andrea ^a,b   Tagliabue, Elda ^a   Sfondrini, Lucia ^b  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

aerosolization; antibiotics; cancer immunosurveillance; immunosuppression and or suppressor cells; lung microbiota; mouse models; probiotics

Indexed keywords

DACARBAZINE; NEOMYCIN; TRANSCRIPTION FACTOR FOXP3; ANTIINFECTIVE AGENT; PROBIOTIC AGENT;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; ESCHERICHIA; ESCHERICHIA FERGUSONII; FEMALE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOSURVEILLANCE; LACTOBACILLUS RHAMNOSUS; LUNG METASTASIS; MACROPHAGE; MICROFLORA; MORGANELLA MORGANII; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY MICROBIOTA; REGULATORY T LYMPHOCYTE; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; LUNG; LUNG TUMOR; MELANOMA; MICROBIOLOGY; PATHOLOGY; TUMOR CELL LINE;

ADMINISTRATION, INHALATION; ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE, TUMOR; CELLS, CULTURED; FEMALE; IMMUNOLOGIC SURVEILLANCE; LUNG; LUNG NEOPLASMS; MELANOMA; MICE; MICE, INBRED C57BL; MICROBIOTA; PROBIOTICS;

EID: 85053806933     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2018.08.090     Document Type: Article

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