The epidemiology of bacterial culture–positive and septic transfusion reactions at a large tertiary academic center: 2009 to 2016

Transfusion

Volumn 58, Issue 8, 2018, Pages 1933-1939

  Erony, Sean M ^a   Marshall, Christi E ^a   Gehrie, Eric A ^a   Boyd, Joan S ^a   Ness, Paul M ^a   Tobian, Aaron A R ^a   Carroll, Karen C ^a   Blagg, Lorraine ^a   Shifflett, Lisa ^a   Bloch, Evan M ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; APHERESIS; ARTICLE; BACTERIUM CULTURE; BLOOD; BLOOD TRANSFUSION REACTION; CHILD; CHILL; CLINICAL FEATURE; CONTROLLED STUDY; DESCRIPTIVE RESEARCH; DISEASE SEVERITY; DISEASE TRANSMISSION; FEMALE; FEVER; GRAM STAINING; HUMAN; HUMAN CELL; INFECTION RISK; LIFE THREAT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NAUSEA AND VOMITING; NONHUMAN; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD; SEPSIS; TERTIARY HEALTH CARE; THROMBOCYTE TRANSFUSION; YOUNG ADULT; MICROBIOLOGICAL EXAMINATION; PROCEDURES; RISK ASSESSMENT; TERTIARY CARE CENTER; UNIVERSITY HOSPITAL;

ACADEMIC MEDICAL CENTERS; BACTERIOLOGICAL TECHNIQUES; HUMANS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; TERTIARY CARE CENTERS; TRANSFUSION REACTION;

EID: 85052811807     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.14789     Document Type: Article

References (27)

1. Fatalities reported to FDA following blood collection and transfusion annual summary for FY2015. Silver Spring (MD): US Food and Drug Administration; 2015
2. Brecher ME, Hay SN. Bacterial contamination of blood components. Clin Microbiol Rev 2005;18:195-204
3. de Korte D, Marcelis JH, Verhoeven AJ, et al. Diversion of first blood volume results in a reduction of bacterial contamination for whole-blood collections. Vox Sang 2002;83:13-6
4. McDonald CP. Interventions implemented to reduce the risk of transmission of bacteria by transfusion in the English National Blood Service. Transfus Med Hemother 2011;38:255-8
5. Eder AF, Dy BA, DeMerse B, et al. Apheresis technology correlates with bacterial contamination of platelets and reported septic transfusion reactions. Transfusion 2017;57:2969-76
6. Ness P, Braine H, King K, et al. Single-donor platelets reduce the risk of septic platelet transfusion reactions. Transfusion 2001;41:857-61
7. Fuller AK, Uglik KM, Savage WJ, et al. Bacterial culture reduces but does not eliminate the risk of septic transfusion reactions to single-donor platelets. Transfusion 2009;49:2588-93
8. Brecher ME, Blajchman MA, Yomtovian R, et al. Addressing the risk of bacterial contamination of platelets within the United States: a history to help illuminate the future. Transfusion 2013;53:221-31
9. Hong H, Xiao W, Lazarus HM, et al. Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance. Blood 2016;127:496-502
10. Bacterial risk control strategies for blood collection establishments and transfusion services to enhance the safety and availability of platelets for transfusion. Silver Spring (MD): Health and Human Services, Food and Drug Administration, Center for Biologics Evaluation and Research; 2016
11. Bloch EM, Marshall CE, Boyd JS, et al. Implementation of secondary bacterial culture testing of platelets to mitigate residual risk of septic transfusion reactions. Transfusion 2018. doi:10.1111/trf.14618 [Epub ahead of print]
12. National healthcare safety network biovigilance component hemovigilance module surveillance protocol. Atlanta: Centers for Disease Control and Prevention; 2017
13. Ramirez-Arcos S, DiFranco C, McIntyre T, et al. Residual risk of bacterial contamination of platelets: six years of experience with sterility testing. Transfusion 2017;57:2174-81
14. Fung MK, Grossman BJ, Hillyer C, et al., editors. AABB technical manual. 18th ed. Bethesda: AABB; 2014
15. Klausen SS, Hervig T, Seghatchian J, et al. Bacterial contamination of blood components: Norwegian strategies in identifying donors with higher risk of inducing septic transfusion reactions in recipients. Transfus Apher Sci 2014;51:97-102
16. Leo AM, Salvadego MM, Piva MG, et al. From the donor's arm to blood product: a study on bacterial contamination of apheresis platelet concentrates. Blood Transfus 2007;5:130-3
17. Eder AF, Kennedy JM, Dy BA, et al. Limiting and detecting bacterial contamination of apheresis platelets: inlet-line diversion and increased culture volume improve component safety. Transfusion 2009;49:1554-63
18. Hendrickson JE, Roubinian NH, Chowdhury D, et al. Incidence of transfusion reactions: a multicenter study utilizing systematic active surveillance and expert adjudication. Transfusion 2016;56:2587-96
19. Jacobs MR, Good CE, Lazarus HM, et al. Relationship between bacterial load, species virulence, and transfusion reaction with transfusion of bacterially contaminated platelets. Clin Infect Dis 2008;46:1214-20
20. Association bulletin #14-04: Re: Clinical recognition and investigation of suspected bacterial contamination of platelets. Bethesda: AABB; 2014
21. Gehrie EA, Roubinian NH, Chowdhury D, et al. A multicentre study investigating vital sign changes occurring in complicated and uncomplicated transfusions. Vox Sang 2017;113:160-9
22. Palavecino EL, Yomtovian RA, Jacobs MR. Detecting bacterial contamination in platelet products. Clin Lab 2006;52:443-56
23. Hume HA, Ddungu H, Angom R, et al. Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions. Transfusion 2016;56:1951-9
24. Murphy WG, Foley M, Doherty C, et al. Screening platelet concentrates for bacterial contamination: low numbers of bacteria and slow growth in contaminated units mandate an alternative approach to product safety. Vox Sang 2008;95:13-9
25. Standards for blood banks and transfusion services. 30th ed. Bethesda: AABB; 2016
26. McDonald C, Allen J, Brailsford S, et al. Bacterial screening of platelet components by National Health Service Blood and Transplant, an effective risk reduction measure. Transfusion 2017;57:1122-31
27. Bloch EM. Residual risk of bacterial contamination: what are the options? Transfusion 2017;57:2289-92