Residual risk of bacterial contamination: what are the options?

Transfusion

Volumn 57, Issue 10, 2017, Pages 2289-2292

  Bloch, Evan M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM CONTAMINATION; BLOOD SAFETY; BLOOD TRANSFUSION; COLORIMETRY; COST; DIAGNOSTIC KIT; EDITORIAL; GENERAL MEDICAL DEVICE; HEMATOLOGICAL PROCEDURE; HUMAN; INFECTION RISK; MICROBIOLOGICAL EXAMINATION; PHOTOCHEMISTRY; RAPID TEST; THROMBOCYTE TRANSFUSION; UNITED STATES; MEDICAL DEVICE CONTAMINATION; RISK;

EQUIPMENT CONTAMINATION; HUMANS; RISK;

EID: 85029789232     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.14306     Document Type: Editorial

References (24)

1. Blajchman MA, Goldman M, Baeza F. Improving the bacteriological safety of platelet transfusions. Transfus Med Rev 2004;18:11-24.
2. McDonald CP. Interventions implemented to reduce the risk of transmission of bacteria by transfusion in the English National Blood Service. Transfus Med Hemother 2011;38:255-8.
3. de Korte D, Marcelis JH, Verhoeven AJ, et al. Diversion of first blood volume results in a reduction of bacterial contamination for whole-blood collections. Vox Sang 2002;83:13-6.
4. Benjamin RJ, Kline L, Dy BA, et al. Bacterial contamination of whole-blood-derived platelets: the introduction of sample diversion and prestorage pooling with culture testing in the American Red Cross. Transfusion 2008;48:2348-55.
5. Ramirez-Arcos S, DiFranco C, McIntyre T, et al. Residual risk of bacterial contamination of platelets: six years of experience with sterility testing. Transfusion. 2017;57:2174-81.
6. US Food and Drug Administration (FDA). Fatalities reported to FDA following blood collection and transfusion annual summary for FY2015. Silver Spring (MD): FDA; 2015.
7. US Food and Drug Administration–Center for Biologics Evaluation and Research (FDA-CBER). Bacterial risk control strategies for blood collection establishments and transfusion services to enhance the safety and availability of platelets for transfusion. Silver Spring (MD): FDA-CBER; 2016.
8. Li JW, Brecher ME, Jacobson JL, et al. Addressing the risk of bacterial contamination in platelets: a hospital economic perspective Transfusion 2017;57:2321-8.
9. Fast LD, Nevola M, Tavares J, et al. Treatment of whole blood with riboflavin plus ultraviolet light, an alternative to gamma irradiation in the prevention of transfusion-associated graft-versus-host disease? Transfusion 2013;53:373-81.
10. Grass JA, Wafa T, Reames A, et al. Prevention of transfusion-associated graft-versus-host disease by photochemical treatment. Blood 1999;93:3140-7.
11. Butler C, Doree C, Estcourt LJ, et al. Pathogen-reduced platelets for the prevention of bleeding. Cochrane Database Syst Rev 2013;3:CD009072.
12. Wald M. Blood industry shrinks as transfusions decline. New York Times; August 23, 2014.
13. Verax Biomedical. Platelet PGD® test. Worcester (MA): Verax Biomedical; 2009.
14. Heaton WA, Good CE, Galloway-Haskins R, et al. Evaluation of a rapid colorimetric assay for detection of bacterial contamination in apheresis and pooled random-donor platelet units. Transfusion 2014;54:1634-41.
15. Larsen CP, Ezligini F, Hermansen NO, et al. Six years' experience of using the BacT/ALERT system to screen all platelet concentrates, and additional testing of outdated platelet concentrates to estimate the frequency of false-negative results. Vox Sang 2005;88:93-7.
16. Murphy WG, Foley M, Doherty C, et al. Screening platelet concentrates for bacterial contamination: low numbers of bacteria and slow growth in contaminated units mandate an alternative approach to product safety. Vox Sang 2008;95:13-9.
17. Mertens G, Muylle L. False-positive and false-negative results of sterility testing of stored platelet concentrates. Transfusion 1999;39:539-40.
18. Ellingson KD, Sapiano MRP, Haass KA, et al. Cost projections for implementation of safety interventions to prevent transfusion-transmitted Zika virus infection in the United States. Transfusion 2017;57 Suppl 2:1625-33.
19. Aubry M, Richard V, Green J, et al. Inactivation of Zika virus in plasma with amotosalen and ultraviolet A illumination. Transfusion 2016;56:33-40.
20. Hume HA, Ddungu H, Angom R, et al. Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions. Transfusion 2016;56:1951-9.
21. Hassall O, Maitland K, Pole L, et al. Bacterial contamination of pediatric whole blood transfusions in a Kenyan hospital. Transfusion 2009;49:2594-8.
22. Jacobs MR, Good CE, Lazarus HM, et al. Relationship between bacterial load, species virulence, and transfusion reaction with transfusion of bacterially contaminated platelets. Clin Infect Dis 2008;46:1214-20.
23. Mohr H, Lambrecht B, Bayer A, et al. Basics of flow cytometry-based sterility testing of platelet concentrates. Transfusion 2006;46:41-9.
24. Vollmer T, Kleesiek K, Dreier J. Detection of bacterial contamination in platelet concentrates using flow cytometry and real-time PCR methods. In: Wilks M, editor. Methods in molecular biology. Totowa (NJ): Humana Press, 2013. p. 91-103