From the donor's arm to blood product: A study on bacterial contamination of apheresis platelet concentrates

Blood Transfusion

Volumn 5, Issue 3, 2007, Pages 130-133

  Leo, Anna Maria ^a   Salvadego, Maria Monica ^a   Piva, Maria Grazia ^a   Ruffato, Graziano ^a   Valverde, Sara ^b   Trabuio, Ernesto ^b   Antico, Francesco ^b   Gessoni, Gianluca ^a,b,c  

^a Centro Trasfusionale A ULS 14   (Italy)

^b Dipartimento di Patologia Clinica A ULS 14 Chioggia   (Italy)

^c Ospedale Civile   (Italy)

Author keywords

Apheresis; Arm disinfection; Microbiological contamination; Platelet concentrates

Indexed keywords

THROMBOCYTE CONCENTRATE;

APHERESIS; ARTICLE; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; BLOOD; BLOOD CULTURE; BLOOD DONOR; BLOOD TRANSFUSION; CONTROLLED STUDY; HUMAN; MICROFLORA; SKIN DECONTAMINATION; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 47749123317     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2007.0003-07     Document Type: Article

References (12)

1. Blajchman A, Beckers A, Dickmeiss E, et al. Bacterial detection of platelets: current problems and possible resolutions. Transfus Med Rev 2005; 19: 259-72.
2. AABB. Standards for Blood Banks and Transfusion Services. Bethesda, MD: AABB 2004.
3. Brecher M, Hay S. Bacterial contamination of blood components. Clin Microbiol Rev 2005; 18: 195-204.
4. Castro E, Bueno J, Barea L, Gonzalez R. Feasibility of implementing an automated culture system for bacteria screening in platelets in the blood bank routine. Transfus Med 2005; 15: 185-95.
5. Morbidity and Mortality Weekly Report. Fatal bacteria infections associated with platelet transfusion. United States 2004. CDC 2005; 54: 168-70. Available at: http//www.cdc.gov/mmwr/preview/mmrhtlm/mm5407a2.htm
6. Yazer M, Triulzi D. Use of a pH meter for bacterial screening of whole blood platelets. Transfusion 2005; 45: 1133-7.
7. McDonald C, Pearce S, Wilkins KC, et al. Pall eBDS: an enhanced bacterial detection system for screening platelet concentrates. Transfus Med 2005; 15: 259-68.
8. Schmidt M, Weis C, Heck J, et al. Optimized Scansystem platelet kit for bacterial detection with enhanced sensitivity: detection within 24 h after spiking. Vox Sang 2005; 89: 135-9.
9. Mohammadi T, Pietersz R, Vandenbroucke-Grauls C, et al. Detection of bacteria in platelet concentrates: comparison of broad-range real-time 16S rDNA polymerase chain reaction and automated culturing. Transfusion 2005; 45: 731-6.
10. McDonald C, Lowe P, Roy A, et al. Evaluation of donor arm disinfection techniques. Vox Sang 2001; 80: 135-41.
11. Hundhausen T, Muller T and the GERMS Group. False positive alarms for bacterial screening of platelet concentrates with BacT/ALERT new generation plastic bottles: a multicentric pilot study. Transfusion 2005; 45: 1267-74.
12. Larsen C, Ezligini F, Hermansen N, Kjeldsen-Kragh J. Six years' experience of using the BacT/ALERT system to screen all platelet concentrates, and additional testing of outdated platelet concentrates to estimate the frequency of falsenegative results. Vox Sang 2005; 88: 93-7.