Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents

European Journal of Medicinal Chemistry

Volumn 157, Issue , 2018, Pages 1017-1030

  Szűcs, Zsolt ^a   Kelemen, Viktor ^a   Le Thai, Son ^a   Csávás, Magdolna ^a   Rőth, Erzsébet ^a   Batta, Gyula ^b   Stevaert, Annelies ^c   Vanderlinden, Evelien ^c   Naesens, Lieve ^c   Herczegh, Pál ^a   Borbás, Anikó ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Coronavirus; Influenza virus inhibitor; Lipoglycopeptide; Maleimide; Sulfonamide; Teicoplanin

Indexed keywords

ALKYL GROUP; AMANTADINE; ANTIVIRUS AGENT; GLYCOL; GLYCOPEPTIDE; MALEIMIDE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RIBAVIRIN; RIMANTADINE; SULFONAMIDE; TEICOPLANIN DERIVATIVE; TRIAZOLE DERIVATIVE; ZANAMIVIR; TEICOPLANIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; CORONAVIRIDAE; CYTOTOXICITY; DRUG CONJUGATION; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFLUENZA A VIRUS; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); INFLUENZA B VIRUS; INFLUENZA VIRUS; LIPOPHILICITY; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; ANALOGS AND DERIVATIVES; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

ANTIVIRAL AGENTS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INFLUENZA A VIRUS; INFLUENZA B VIRUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TEICOPLANIN;

EID: 85052300271     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2018.08.058     Document Type: Article

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