메뉴 건너뛰기




Volumn 12, Issue 1, 2018, Pages 59-68

In vitro and in vivo immunomodulating properties of mesenchymal stem cells

Author keywords

Cytokines; Immunomodulation; Inflammation; Mesenchymal stem cells (MSCs); T cells; Therapeutic properties; Tregs

Indexed keywords

PROSTAGLANDIN E2; TRANSCRIPTION FACTOR FOXP3; NITRIC OXIDE;

EID: 85052079932     PISSN: 1872213X     EISSN: 22122710     Source Type: Journal    
DOI: 10.2174/1872213X12666180227105924     Document Type: Review
Times cited : (14)

References (136)
  • 1
    • 84876190903 scopus 로고    scopus 로고
    • The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation
    • Kim EJ, Kim N, Cho SG. The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation. Exp Mol Med 2013; 45: e2.
    • (2013) Exp Mol Med , vol.45 , pp. 2
    • Kim, E.J.1    Kim, N.2    Cho, S.G.3
  • 2
    • 85052333844 scopus 로고    scopus 로고
    • Immunomodulatory effect of allogenic bone marrow-derived mesenchymal stem cells on salmonella-derived flagellin
    • Chaudhary D, Goswami TK, Munjal, AK, Singh, M, Ram, GC. Immunomodulatory effect of allogenic bone marrow-derived mesenchymal stem cells on salmonella-derived flagellin. Vet Immunol Immunop 2012; 14(1): 22-8.
    • (2012) Vet Immunol Immunop , vol.14 , Issue.1 , pp. 22-28
    • Chaudhary, D.1    Goswami, T.K.2    Munjal, A.K.3    Singh, M.4    Ram, G.C.5
  • 4
    • 33751168064 scopus 로고    scopus 로고
    • Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue
    • Izadpanah R, Trygg C, Patel B, Kriedt C, Dufour J, Gimble JM, et al. Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue. J Cell Biochem 2006; 99: 1285-97.
    • (2006) J Cell Biochem , vol.99 , pp. 1285-1297
    • Izadpanah, R.1    Trygg, C.2    Patel, B.3    Kriedt, C.4    Dufour, J.5    Gimble, J.M.6
  • 5
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: Implications for cell-based therapies
    • Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, et al. Multilineage cells from human adipose tissue: Implications for cell-based therapies. Tissue Eng 2001; 7: 211-28.
    • (2001) Tissue Eng , vol.7 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3    Huang, J.4    Futrell, J.W.5    Katz, A.J.6
  • 7
    • 37549009470 scopus 로고    scopus 로고
    • Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: Comparison to bone marrow mesenchymal stem cells
    • Roubelakis MG, Pappa KI, Bitsika V, Zagoura D, Vlahou A, Pa-padaki HA, et al. Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: Comparison to bone marrow mesenchymal stem cells. Stem Cells Dev 2007; 16: 931-52.
    • (2007) Stem Cells Dev , vol.16 , pp. 931-952
    • Roubelakis, M.G.1    Pappa, K.I.2    Bitsika, V.3    Zagoura, D.4    Vlahou, A.5    Pa-Padaki, H.A.6
  • 8
    • 3543003475 scopus 로고    scopus 로고
    • Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood
    • Erices K, Kern S, Kluter H, Eichler H. Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells 2004; 22: 625-34.
    • (2004) Stem Cells , vol.22 , pp. 625-634
    • Erices, K.1    Kern, S.2    Kluter, H.3    Eichler, H.4
  • 9
    • 33750233770 scopus 로고    scopus 로고
    • Immunoregulatory function of mesenchymal stem cells
    • Uccelli A, Moretta L, Pistoia V. Immunoregulatory function of mesenchymal stem cells. Eur J Immunol 2006; 36: 2566-73.
    • (2006) Eur J Immunol , vol.36 , pp. 2566-2573
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 10
    • 67649888792 scopus 로고    scopus 로고
    • The immunosuppressive properties of mesenchymal stem cells
    • Siegel G, Schafer R, Dazzi F. The immunosuppressive properties of mesenchymal stem cells. Transplantation 2009; 87(Suppl 9): S45-9.
    • (2009) Transplantation , vol.87 , pp. S45-S49
    • Siegel, G.1    Schafer, R.2    Dazzi, F.3
  • 11
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yanez R, Lamana ML, Garcia-Castro J, Colmenero I, Ramirez M, Bueren JA. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells Dev 2006; 24: 2582-91.
    • (2006) Stem Cells Dev , vol.24 , pp. 2582-2591
    • Yanez, R.1    Lamana, M.L.2    Garcia-Castro, J.3    Colmenero, I.4    Ramirez, M.5    Bueren, J.A.6
  • 13
    • 72049097674 scopus 로고    scopus 로고
    • The role of dendritic cells and regulatory T cells in the regulation of allergic asthma
    • Burchell JT, Strickland DH, Stumbles PA. The role of dendritic cells and regulatory T cells in the regulation of allergic asthma. Pharmacol Ther 2010; 125: 1-10.
    • (2010) Pharmacol Ther , vol.125 , pp. 1-10
    • Burchell, J.T.1    Strickland, D.H.2    Stumbles, P.A.3
  • 14
    • 62549157393 scopus 로고    scopus 로고
    • Brief report-human embryonic stem cell-derived mesenchymal progenitors possess strong immunosuppressive effects toward natural killer cells as well as T lymphocytes
    • Yen BL, Chang CJ, Liu KJ, Chen YC, Hu HI, Bai CH et al. Brief report-human embryonic stem cell-derived mesenchymal progenitors possess strong immunosuppressive effects toward natural killer cells as well as T lymphocytes. Stem Cells 2009; 27: 451-6.
    • (2009) Stem Cells , vol.27 , pp. 451-456
    • Yen, B.L.1    Chang, C.J.2    Liu, K.J.3    Chen, Y.C.4    Hu, H.I.5    Bai, C.H.6
  • 15
    • 84875183630 scopus 로고    scopus 로고
    • Novel and emerging therapies safeguarding health of humans and their companion animals: A review
    • Dhama K, Chakraborty S, Mahima, Wani MY, Verma AK, Deb R, et al. Novel and emerging therapies safeguarding health of humans and their companion animals: A review. Pak. J. Biol. Sci. 2013; 16(3): 101-11.
    • (2013) Pak. J. Biol. Sci. , vol.16 , Issue.3 , pp. 101-111
    • Dhama, K.1    Chakraborty, S.2    Mahima, W.M.Y.3    Verma, A.K.4    Deb, R.5
  • 16
    • 85041414247 scopus 로고    scopus 로고
    • Bacterial toxins: A hope towards angiogenic ailments
    • Khandia R, Munjal A, Dhama K, Malik YS. Bacterial toxins: A hope towards angiogenic ailments. Curr Drug Metab 2017;18(10): 926-41.
    • (2017) Curr Drug Metab , vol.18 , Issue.10 , pp. 926-941
    • Khandia, R.1    Munjal, A.2    Dhama, K.3    Malik, Y.S.4
  • 17
    • 85026467127 scopus 로고    scopus 로고
    • Cell penetrating peptides: Biomedical/therapeutic applications with emphasis as promising futuristic hope for treating cancer
    • Khandia R, Munjal A, Kumar A, Singh G, Karthik K, Dhama K. Cell penetrating peptides: Biomedical/therapeutic applications with emphasis as promising futuristic hope for treating cancer. Int J Pharmacol 2017; 13(7): 677-89.
    • (2017) Int J Pharmacol , vol.13 , Issue.7 , pp. 677-689
    • Khandia, R.1    Munjal, A.2    Kumar, A.3    Singh, G.4    Karthik, K.5    Dhama, K.6
  • 18
    • 85041394816 scopus 로고    scopus 로고
    • Anti-proliferative role of recombinant lethal toxin of Bacillus anthracis on primary mammary ductal carcinoma cells revealing its therapeutic potential
    • Khandia R, Pattnaik B, Rajukumar K, Pateriya A, Bhatia S, Murugkar H, et al. Anti-proliferative role of recombinant lethal toxin of Bacillus anthracis on primary mammary ductal carcinoma cells revealing its therapeutic potential. Oncotarget 2017; 8(22): 35835-47.
    • (2017) Oncotarget , vol.8 , Issue.22 , pp. 35835-35847
    • Khandia, R.1    Pattnaik, B.2    Rajukumar, K.3    Pateriya, A.4    Bhatia, S.5    Murugkar, H.6
  • 19
    • 85029636724 scopus 로고    scopus 로고
    • Evaluation of silver nanoparticle mediated reduction of neovascularisation (Angiogenesis) in chicken model
    • Khandia R, Munjal A, Bangrey RS, Mehra R, Dhama K, Sharma NC. Evaluation of silver nanoparticle mediated reduction of neovascularisation (angiogenesis) in chicken model. Adv Anim Vet Sci 2015; 3(7): 372-6.
    • (2015) Adv Anim Vet Sci , vol.3 , Issue.7 , pp. 372-376
    • Khandia, R.1    Munjal, A.2    Bangrey, R.S.3    Mehra, R.4    Dhama, K.5    Sharma, N.C.6
  • 20
    • 85034653576 scopus 로고    scopus 로고
    • Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world
    • Prasad M, Lambe UP, Brar B, Shah I, Koushlesh Ranjan MJ, Rao R, et al. Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world. Biomed Pharmaco 2018; 97: 1521-37.
    • (2018) Biomed Pharmaco , vol.97 , pp. 1521-1537
    • Prasad, M.1    Lambe, U.P.2    Brar, B.3    Shah, I.4    Koushlesh Ranjan, M.J.5    Rao, R.6
  • 22
    • 85010440316 scopus 로고    scopus 로고
    • Evaluation of the modulatory effects of copper salts on the process of Angiogenesis (Neovascularization) with therapeutic perspectives
    • Khandia R, Vishwakarma P, Dwivedi A, Mehra R, Kujur A, Dhama K, et al. Evaluation of the modulatory effects of copper salts on the process of Angiogenesis (Neovascularization) with therapeutic perspectives. Adv Anim Vet Sci 2016; 4 (8), 405-10.
    • (2016) Adv Anim Vet Sci , vol.4 , Issue.8 , pp. 405-410
    • Khandia, R.1    Vishwakarma, P.2    Dwivedi, A.3    Mehra, R.4    Kujur, A.5    Dhama, K.6
  • 23
    • 84964273471 scopus 로고    scopus 로고
    • Clinical trials with mesenchymal stem cells: An update
    • Squillaro T, Peluso G, Galderisi U. Clinical trials with mesenchymal stem cells: An update. Cell Transplant 2016; 25(5): 829-48.
    • (2016) Cell Transplant , vol.25 , Issue.5 , pp. 829-848
    • Squillaro, T.1    Peluso, G.2    Galderisi, U.3
  • 25
    • 84954189935 scopus 로고    scopus 로고
    • MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry
    • L Ramos T, Sánchez-Abarca LI, Muntión S, Preciado S, Puig N, López-Ruano G, et al. MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry. Cell Commun Signal 2016; 14: 2.
    • (2016) Cell Commun Signal , vol.14 , pp. 2
    • Ramos, L.1    Sánchez-Abarca, L.I.2    Muntión, S.3    Preciado, S.4    Puig, N.5    López-Ruano, G.6
  • 26
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini FC, Krause DS, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8(4): 315-7.
    • (2006) Cytotherapy , vol.8 , Issue.4 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.C.5    Krause, D.S.6
  • 28
    • 42049088752 scopus 로고    scopus 로고
    • Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody
    • Battula VL, Treml S, Abele H, Bühring HJ. Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. Differentiation 2008; 76: 326-36.
    • (2008) Differentiation , vol.76 , pp. 326-336
    • Battula, V.L.1    Treml, S.2    Abele, H.3    Bühring, H.J.4
  • 29
    • 85035065066 scopus 로고    scopus 로고
    • Concise Review: Multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine
    • Samsonraj RM, Raghunath M, Nurcombe V, Hui JH, van Wijnen AJ, Cool SM. Concise Review: Multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine. Stem Cells Transl Med 2017; 6(12): 2173-85.
    • (2017) Stem Cells Transl Med , vol.6 , Issue.12 , pp. 2173-2185
    • Samsonraj, R.M.1    Raghunath, M.2    Nurcombe, V.3    Hui, J.H.4    van Wijnen, A.J.5    Cool, S.M.6
  • 30
    • 84901477349 scopus 로고    scopus 로고
    • Concise review: The surface markers and identity of human mesenchymal stem cells
    • Lv FJ, Tuan RS, Cheung KM, Leung VY. Concise review: The surface markers and identity of human mesenchymal stem cells. Stem Cells 2014; 32(6): 1408-19.
    • (2014) Stem Cells , vol.32 , Issue.6 , pp. 1408-1419
    • Lv, F.J.1    Tuan, R.S.2    Cheung, K.M.3    Leung, V.Y.4
  • 31
    • 84963850088 scopus 로고    scopus 로고
    • Separation of mesenchymal stem cells through a strategic centrifugation protocol
    • Ferlin KM, Kaplan DS, Fisher JP. Separation of mesenchymal stem cells through a strategic centrifugation protocol. Tissue Eng Part C Methods 2016; 22(4): 348-59.
    • (2016) Tissue Eng Part C Methods , vol.22 , Issue.4 , pp. 348-359
    • Ferlin, K.M.1    Kaplan, D.S.2    Fisher, J.P.3
  • 32
    • 84894059491 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning
    • Boyette LB, Creasey OA, Guzik L, Lozito T, Tuan RS. Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning. Stem Cells Transl Med. 2014; 3(2): 241-54.
    • (2014) Stem Cells Transl Med , vol.3 , Issue.2 , pp. 241-254
    • Boyette, L.B.1    Creasey, O.A.2    Guzik, L.3    Lozito, T.4    Tuan, R.S.5
  • 34
    • 77952893038 scopus 로고    scopus 로고
    • Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemia model via direct cell-to-cell connections
    • Cselenyák A, Pankotai E, Horváth EM, Kiss L, Lacza Z. Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemia model via direct cell-to-cell connections. BMC Cell Biol 2010; 11: 29.
    • (2010) BMC Cell Biol , vol.11 , pp. 29
    • Cselenyák, A.1    Pankotai, E.2    Horváth, E.M.3    Kiss, L.4    Lacza, Z.5
  • 35
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian JA, Aviv H, Ponzio NM, Harrison JS, Rameshwar P. Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J Immunol 2003; 171: 3426-34.
    • (2003) J Immunol , vol.171 , pp. 3426-3434
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshwar, P.5
  • 36
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002: 99: 3838-43.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 37
    • 0038204193 scopus 로고    scopus 로고
    • Bone Marrow mesenchymal stem cells inhibit the response of naïve and memory antigen specific T cells to their cognate peptide
    • Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E, Dazzi F. Bone Marrow mesenchymal stem cells inhibit the response of naïve and memory antigen specific T cells to their cognate peptide. Blood 2003; 101: 3722-9.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6    Dazzi, F.7
  • 38
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytesor natural killer cells
    • Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytesor natural killer cells. Transplantation 2003; 76: 1208-13.
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 39
    • 18844404360 scopus 로고    scopus 로고
    • Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway
    • Augello A, Tasso R, Negrini SM, Amateis A, Indiveri F, Cancedda R, et al. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol 2005; 35: 1482-90.
    • (2005) Eur J Immunol , vol.35 , pp. 1482-1490
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Amateis, A.4    Indiveri, F.5    Cancedda, R.6
  • 40
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C, Tropel P, Apparailly F, Sany J, et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003; 102: 3837-44.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5    Sany, J.6
  • 41
    • 85041919759 scopus 로고    scopus 로고
    • Differentiation of MSCs from human iPSCs result in downregulation of c-Myc & DNA replication pathways with immunomodulation toward CD4 & CD8 cells
    • Wang LT, Jiang SS, Ting CH, Hsu PJ, Chang CC, Sytwu HK, et al. Differentiation of MSCs from human iPSCs result in downregulation of c-Myc & DNA replication pathways with immunomodulation toward CD4 & CD8 cells. Stem Cells 2018. doi: 10.1002/stem.2795.
    • (2018) Stem Cells
    • Wang, L.T.1    Jiang, S.S.2    Ting, C.H.3    Hsu, P.J.4    Chang, C.C.5    Sytwu, H.K.6
  • 42
    • 84866463419 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis
    • Fu QL, Chow YY, Sun SJ, Zeng QX, Li HB, Shi JB et al. Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis. Allergy 2012; 67: 1215-22.
    • (2012) Allergy , vol.67 , pp. 1215-1222
    • Fu, Q.L.1    Chow, Y.Y.2    Sun, S.J.3    Zeng, Q.X.4    Li, H.B.5    Shi, J.B.6
  • 43
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation. Transplantation 2003; 75: 389-97.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 44
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005; 105: 1815-22.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 45
    • 15044348816 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibitlymphocytes proliferation by mitogens and alloantigens by different mechanisms
    • Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibitlymphocytes proliferation by mitogens and alloantigens by different mechanisms. Exp Cell Res 2005; 305: 33-41.
    • (2005) Exp Cell Res , vol.305 , pp. 33-41
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 46
    • 79952482065 scopus 로고    scopus 로고
    • Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells
    • Crop MJ, Baan CC, Korevaar SS, Ijzermans JN, Pescatori M, and Stubbs AP, et al. Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells. Clin Exp Immunol 2010; 162: 474-86.
    • (2010) Clin Exp Immunol , vol.162 , pp. 474-486
    • Crop, M.J.1    Baan, C.C.2    Korevaar, S.S.3    Ijzermans, J.N.4    Pescatori, M.5    Stubbs, A.P.6
  • 47
    • 84922505648 scopus 로고    scopus 로고
    • Influence of inflammation on the immunological profile of adult-derived human liver mesenchymal stromal cells and stellate cells
    • Raicevic G, Najar M, Najimi M, El Taghdouini A, van Grunsven LA, Sokal E, et al. Influence of inflammation on the immunological profile of adult-derived human liver mesenchymal stromal cells and stellate cells. Cytotherapy 2015; 17: 174-85.
    • (2015) Cytotherapy , vol.17 , pp. 174-185
    • Raicevic, G.1    Najar, M.2    Najimi, M.3    El Taghdouini, A.4    van Grunsven, L.A.5    Sokal, E.6
  • 48
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2, 3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2, 3-dioxygenase-mediated tryptophan degradation. Blood 2004; 103: 4619-21.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 49
    • 85013630894 scopus 로고    scopus 로고
    • Proteasomal indoleamine 2,3-dioxygenase degradation reduces the immunosuppressive potential of clinical grade-mesenchymal stromal cells undergoing replicative senescence
    • Loisel S, Dulong J, Ménard C, Renoud ML, Meziere N, Isabelle B, et al. Proteasomal indoleamine 2,3-dioxygenase degradation reduces the immunosuppressive potential of clinical grade-mesenchymal stromal cells undergoing replicative senescence. Stem Cells 2017; 35(5):1431-6. doi: 10.1002/stem.2580.
    • (2017) Stem Cells , vol.35 , Issue.5 , pp. 1431-1436
    • Loisel, S.1    Dulong, J.2    Ménard, C.3    Renoud, M.L.4    Meziere, N.5    Isabelle, B.6
  • 51
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, Ger-doni E, et al. Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 2005; 106:1755-61.
    • (2005) Blood , vol.106 , pp. 1755-1761
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3    Benvenuto, F.4    Bonanni, I.5    Ger-Doni, E.6
  • 52
    • 47249155734 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing interleukin-10 attenuate colla-gen-induced arthritis in mice
    • Choi JJ, Yoo SA, Park SJ, Kang YJ, Kim WU, Oh IH, et al. Mesenchymal stem cells overexpressing interleukin-10 attenuate colla-gen-induced arthritis in mice. Clin Exp Immunol 2008; 153(2): 269-76.
    • (2008) Clin Exp Immunol , vol.153 , Issue.2 , pp. 269-276
    • Choi, J.J.1    Yoo, S.A.2    Park, S.J.3    Kang, Y.J.4    Kim, W.U.5    Oh, I.H.6
  • 53
    • 85030323259 scopus 로고    scopus 로고
    • Interleukin-10 secreted by mesenchymal stem cells attenuates acute liver failure through inhibiting pyroptosis
    • Wang J, Ren H, Yuan X, Ma H, Shi X, Ding Y. Interleukin-10 secreted by mesenchymal stem cells attenuates acute liver failure through inhibiting pyroptosis. Hepatol Res 2018; 48(3): E194-202.
    • (2018) Hepatol Res , vol.48 , Issue.3 , pp. E194-E202
    • Wang, J.1    Ren, H.2    Yuan, X.3    Ma, H.4    Shi, X.5    Ding, Y.6
  • 54
    • 85015327158 scopus 로고    scopus 로고
    • ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells
    • Lee HJ, Kim SN, Jeon MS, Yi T, Song SU. ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells. Sci Rep 2017; 7: 44486.
    • (2017) Sci Rep , vol.7
    • Lee, H.J.1    Kim, S.N.2    Jeon, M.S.3    Yi, T.4    Song, S.U.5
  • 55
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regula-tory/suppressive phenotype
    • Maccario R, Podesta M, Moretta A, Cometa A, Comoli P, Montagna D, et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regula-tory/suppressive phenotype. Haematologica 2005; 90: 516-25.
    • (2005) Haematologica , vol.90 , pp. 516-525
    • Maccario, R.1    Podesta, M.2    Moretta, A.3    Cometa, A.4    Comoli, P.5    Montagna, D.6
  • 56
    • 85052321541 scopus 로고    scopus 로고
    • The immunomodulatory properties of adipose mesenchymal stem cell-derived exosomes are induced by inflammatory cytokines
    • Domenis, R, Quaglia, S, Cifù, A, C Pistis, Fabris M, Moretti M, et al. The immunomodulatory properties of adipose mesenchymal stem cell-derived exosomes are induced by inflammatory cytokines. The FASEB Journal 2017; 31(Suppl 1): 981-5.
    • (2017) The FASEB Journal , vol.31 , pp. 981-985
    • Domenis, R.1    Quaglia, S.2    Cifù, A.3    Pistis, C.4    Fabris, M.5    Moretti, M.6
  • 57
    • 85018867979 scopus 로고    scopus 로고
    • Adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory properties in a tissue specific manner
    • Munir H, Ward LSC, Sheriff L, Kemble S, Nayar S, Barone F, et al. Adipogenic differentiation of mesenchymal stem cells alters their immunomodulatory properties in a tissue specific manner. Stem Cells 2017; 35(6):1636-46.
    • (2017) Stem Cells , vol.35 , Issue.6 , pp. 1636-1646
    • Munir, H.1    Ward, L.S.C.2    Sheriff, L.3    Kemble, S.4    Nayar, S.5    Barone, F.6
  • 58
    • 84921044549 scopus 로고    scopus 로고
    • Immunomodulatory characteristics of mesenchymal stem cells and their role in the treatment of multiple sclerosis
    • Gharibi T, Ahmadi M, Seyfizadeh N, Jadidi-Niaragh F, Yousefi M. Immunomodulatory characteristics of mesenchymal stem cells and their role in the treatment of multiple sclerosis. Cell Immunol 2015; 293(2): 113-21.
    • (2015) Cell Immunol , vol.293 , Issue.2 , pp. 113-121
    • Gharibi, T.1    Ahmadi, M.2    Seyfizadeh, N.3    Jadidi-Niaragh, F.4    Yousefi, M.5
  • 78
    • 33846483151 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: Impact on in vivo tumor growth
    • Ramasamy R, Lam EW, Soeiro I, Tisato V, Bonnet D, Dazzi F. Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: Impact on in vivo tumor growth. Leukemia 2006; 21: 304-10.
    • (2006) Leukemia , vol.21 , pp. 304-310
    • Ramasamy, R.1    Lam, E.W.2    Soeiro, I.3    Tisato, V.4    Bonnet, D.5    Dazzi, F.6
  • 79
    • 33846006154 scopus 로고    scopus 로고
    • Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
    • Sato K, Ozaki K, Oh I, Meguro A, Hatanaka K, Nagai T, et al. Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007; 109: 228-34.
    • (2007) Blood , vol.109 , pp. 228-234
    • Sato, K.1    Ozaki, K.2    Oh, I.3    Meguro, A.4    Hatanaka, K.5    Nagai, T.6
  • 80
    • 84908132425 scopus 로고    scopus 로고
    • Plasticity of mesenchymal stem cells in immunomodulation: Pathological and therapeutic implications
    • Wang Y, Chen X, Cao W, Shi Y. Plasticity of mesenchymal stem cells in immunomodulation: Pathological and therapeutic implications. Nat Immunol 2014; 15:1009-16.
    • (2014) Nat Immunol , vol.15 , pp. 1009-1016
    • Wang, Y.1    Chen, X.2    Cao, W.3    Shi, Y.4
  • 81
    • 33846894711 scopus 로고    scopus 로고
    • New perspectives on the mechanisms through which nitric oxide may affect learning and memory processes
    • Edwards TM, Rickard NS. New perspectives on the mechanisms through which nitric oxide may affect learning and memory processes. Neurosci Biobehav Rev 2007; 31: 413-25.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 413-425
    • Edwards, T.M.1    Rickard, N.S.2
  • 82
    • 33750689471 scopus 로고    scopus 로고
    • Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development
    • Murad, F. Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development. N Engl J Med 2006; 355: 2003-11.
    • (2006) N Engl J Med , vol.355 , pp. 2003-2011
    • Murad, F.1
  • 83
    • 33750374586 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of T cell functions
    • Niedbala W, Cai B, Liew FY. Role of nitric oxide in the regulation of T cell functions. Ann Rheum Dis 2006; 65(Suppl 3): 337-40.
    • (2006) Ann Rheum Dis , vol.65 , pp. 337-340
    • Niedbala, W.1    Cai, B.2    Liew, F.Y.3
  • 84
    • 0037183897 scopus 로고    scopus 로고
    • Differential modulation of CD4 and CD8 T-cell proliferation by induction of nitric oxide synthesis in antigen presenting cells
    • Hoffman RA, Mahidhara RS, Wolf-Johnston AS, Lu L, Thomson AW, Simmons, RL. Differential modulation of CD4 and CD8 T-cell proliferation by induction of nitric oxide synthesis in antigen presenting cells. Transplantation 2002; 74: 836-45.
    • (2002) Transplantation , vol.74 , pp. 836-845
    • Hoffman, R.A.1    Mahidhara, R.S.2    Wolf-Johnston, A.S.3    Lu, L.4    Thomson, A.W.5    Simmons, R.L.6
  • 85
    • 84975214996 scopus 로고    scopus 로고
    • Mesenchymal stem cells and immunomodulation: Current status and future prospects
    • Gao F, Chiu SM, Motan DA, Zhang Z, Chen L, Ji HL, et al. Mesenchymal stem cells and immunomodulation: Current status and future prospects. Cell Death Dis 2016; 7: e2062.
    • (2016) Cell Death Dis , vol.7
    • Gao, F.1    Chiu, S.M.2    Motan, D.A.3    Zhang, Z.4    Chen, L.5    Ji, H.L.6
  • 86
    • 9444292842 scopus 로고    scopus 로고
    • Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction
    • Kawada H, Fujita J, Kinjo K, Matsuzaki Y, Tsuma M, Miyatake H, et al. Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood 2004; 104: 3581-7.
    • (2004) Blood , vol.104 , pp. 3581-3587
    • Kawada, H.1    Fujita, J.2    Kinjo, K.3    Matsuzaki, Y.4    Tsuma, M.5    Miyatake, H.6
  • 87
    • 27744485016 scopus 로고    scopus 로고
    • Mobilization of bone marrow-derived progenitor cells in acute coronary syndromes
    • Wojakowski W, Tendera M. Mobilization of bone marrow-derived progenitor cells in acute coronary syndromes. Folia Histochem Cy-tobiol 2005; 43: 229-32.
    • (2005) Folia Histochem Cy-Tobiol , vol.43 , pp. 229-232
    • Wojakowski, W.1    Tendera, M.2
  • 88
    • 36248932643 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features and potential for homing
    • Chamberlain G, Fox J, Ashton B. and Middleton J. Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features and potential for homing. Stem Cells 2007; 25: 2739-49.
    • (2007) Stem Cells , vol.25 , pp. 2739-2749
    • Chamberlain, G.1    Fox, J.2    Ashton, B.3    Middleton, J.4
  • 91
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • Ren G, Zhang L, Zhao X, Xu G, Zhang Y, Roberts AI, et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2: 141-50.
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6
  • 92
    • 84982803315 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stem cells can mitigate oxidative stress and inflammation process in human mustard lung
    • Nejad-Moghaddam A, Ajdary S, Tahmasbpour E, Rad FR, Panahi Yand Ghanei M. Immunomodulatory properties of mesenchymal stem cells can mitigate oxidative stress and inflammation process in human mustard lung. Biochem Genet 2016; 54(6): 769-83.
    • (2016) Biochem Genet , vol.54 , Issue.6 , pp. 769-783
    • Nejad-Moghaddam, A.1    Ajdary, S.2    Tahmasbpour, E.3    Rad, F.R.4    Panahi Yand Ghanei, M.5
  • 93
    • 18644370435 scopus 로고    scopus 로고
    • Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
    • Djouad F, Fritz V, Apparailly F, Louis-Plence P, Bony C, Sany J, et al. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 2005; 52: 1595-603.
    • (2005) Arthritis Rheum , vol.52 , pp. 1595-1603
    • Djouad, F.1    Fritz, V.2    Apparailly, F.3    Louis-Plence, P.4    Bony, C.5    Sany, J.6
  • 94
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004; 363: 1439-41.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassan, M.5    Uzunel, M.6
  • 95
    • 34548610480 scopus 로고    scopus 로고
    • In-trapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    • Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA. In-trapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007; 179: 1855-63.
    • (2007) J Immunol , vol.179 , pp. 1855-1863
    • Gupta, N.1    Su, X.2    Popov, B.3    Lee, J.W.4    Serikov, V.5    Matthay, M.A.6
  • 96
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002; 30: 42-8.
    • (2002) Exp Hematol , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3    Ferrer, K.4    McIntosh, K.5    Patil, S.6
  • 97
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EGA, Wil-lemze R, Fibbe WE. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006; 108: 2114-20.
    • (2006) Blood , vol.108 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.A.4    Wil-Lemze, R.5    Fibbe, W.E.6
  • 98
    • 33744917000 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells suppress lympho-cyte proliferation in vitro but fail to prevent graft-versus-host disease in mice
    • Sudres M, Norol F, Trenado A, Gregoire S, Charlotte F, Levacher B, et al. Bone marrow mesenchymal stem cells suppress lympho-cyte proliferation in vitro but fail to prevent graft-versus-host disease in mice. J Immunol 2006; 176: 7761-7.
    • (2006) J Immunol , vol.176 , pp. 7761-7767
    • Sudres, M.1    Norol, F.2    Trenado, A.3    Gregoire, S.4    Charlotte, F.5    Levacher, B.6
  • 99
    • 85019814205 scopus 로고    scopus 로고
    • Mesenchymal stromal cells and autoimmunity
    • Pistoia V, Raffaghello L. Mesenchymal stromal cells and autoimmunity. Int Immunol 2017; 29(2): 49-58.
    • (2017) Int Immunol , vol.29 , Issue.2 , pp. 49-58
    • Pistoia, V.1    Raffaghello, L.2
  • 100
    • 23644458723 scopus 로고    scopus 로고
    • Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice
    • Zhang J, Li Y, Chen J, Cui Y, Lu M, Elias SB, et al. Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice. Exp Neurol 2005; 195: 16-26.
    • (2005) Exp Neurol , vol.195 , pp. 16-26
    • Zhang, J.1    Li, Y.2    Chen, J.3    Cui, Y.4    Lu, M.5    Elias, S.B.6
  • 101
    • 84963815391 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stem cell in experimental arthritis in rat and mouse models: A systematic review
    • Hynes K, Bright R, Proudman S, Haynes D, Gronthos S, Bartold M. Immunomodulatory properties of mesenchymal stem cell in experimental arthritis in rat and mouse models: A systematic review. Semin Arthritis Rheum 2016; 46(1): 1-19.
    • (2016) Semin Arthritis Rheum , vol.46 , Issue.1 , pp. 1-19
    • Hynes, K.1    Bright, R.2    Proudman, S.3    Haynes, D.4    Gronthos, S.5    Bartold, M.6
  • 102
    • 85040967638 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells suppress IL9 in adjuvant-induced arthritis
    • Abd Elhalem SS, Haggag NZ, El-Shinnawy NA. Bone marrow mesenchymal stem cells suppress IL9 in adjuvant-induced arthritis. Autoimmunity 2018; 51(1): 25-34.
    • (2018) Autoimmunity , vol.51 , Issue.1 , pp. 25-34
    • Abd Elhalem, S.S.1    Haggag, N.Z.2    El-Shinnawy, N.A.3
  • 103
    • 33645984161 scopus 로고    scopus 로고
    • Amelioration of acute renal failure by stem cell therapy-paracrine secretion versus trans-differentiation into resident cells
    • Togel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Amelioration of acute renal failure by stem cell therapy-paracrine secretion versus trans-differentiation into resident cells. J Am Soc Nephrol 2005; 16(5): 1153-63.
    • (2005) J am Soc Nephrol , vol.16 , Issue.5 , pp. 1153-1163
    • Togel, F.1    Hu, Z.2    Weiss, K.3    Isaac, J.4    Lange, C.5    Westenfelder, C.6
  • 104
    • 33746547311 scopus 로고    scopus 로고
    • Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis
    • Kunter U, Rong S, Djuric Z, Boor P, Müller-Newen G, Yu D, et al. Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. J Am Soc Nephrol 2006; 17: 2202-12.
    • (2006) J am Soc Nephrol , vol.17 , pp. 2202-2212
    • Kunter, U.1    Rong, S.2    Djuric, Z.3    Boor, P.4    Müller-Newen, G.5    Yu, D.6
  • 105
    • 0036644833 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
    • Studeny M, Marini FC, Champlin, RE, Zompetta C, Fidler IJ, An-dreeff M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 2002; 62: 3603-8.
    • (2002) Cancer Res , vol.62 , pp. 3603-3608
    • Studeny, M.1    Marini, F.C.2    Champlin, R.E.3    Zompetta, C.4    Fidler, I.J.5    An-Dreeff, M.6
  • 107
    • 79959788940 scopus 로고    scopus 로고
    • Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses
    • Moll G, Jitschin R, von Bahr L, Rasmusson-Duprez I, Sundberg B, Lönnies L, et al. Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses. PLOS One 2011; 6(7): e21703.
    • (2011) PLOS One , vol.6 , Issue.7
    • Moll, G.1    Jitschin, R.2    von Bahr, L.3    Rasmusson-Duprez, I.4    Sundberg, B.5    Lönnies, L.6
  • 109
    • 70349883762 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis
    • Rafei M, Birman E, Forner K, Galipeau J. Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis. Mol Ther. 2009; 17(10): 1799-1803. doi: 10.1038/mt.2009.157.
    • (2009) Mol Ther , vol.17 , Issue.10 , pp. 1799-1803
    • Rafei, M.1    Birman, E.2    Forner, K.3    Galipeau, J.4
  • 110
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • Ren G, Zhang L, Zhao X, Xu G, Zhang Y, Roberts AI, et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2(2): 141-50.
    • (2008) Cell Stem Cell , vol.2 , Issue.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6
  • 111
    • 85012054550 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis through transplantation of placental derived mesenchymal stem cells
    • Jiang H, Zhang Y, Tian K, Wang B, Han S. Amelioration of experimental autoimmune encephalomyelitis through transplantation of placental derived mesenchymal stem cells. Sci Rep 2017; 7: 41837.
    • (2017) Sci Rep , vol.7
    • Jiang, H.1    Zhang, Y.2    Tian, K.3    Wang, B.4    Han, S.5
  • 112
    • 33846217749 scopus 로고    scopus 로고
    • Mesenchymal stem cells facilitate the induction of mixed hematopoietic chimerism and islet allograft tolerance without GVHD in the rat
    • Itakura S, Asari S, Rawson J, Ito T, Todorov I, Liu CP, et al. Mesenchymal stem cells facilitate the induction of mixed hematopoietic chimerism and islet allograft tolerance without GVHD in the rat. Am J Transplant 2007; 7: 336-46.
    • (2007) Am J Transplant , vol.7 , pp. 336-346
    • Itakura, S.1    Asari, S.2    Rawson, J.3    Ito, T.4    Todorov, I.5    Liu, C.P.6
  • 115
    • 1542286220 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Clinical applications and biological characterization
    • Barry FP, Murphy JM. Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 2004; 36(4): 568-84.
    • (2004) Int J Biochem Cell Biol , vol.36 , Issue.4 , pp. 568-584
    • Barry, F.P.1    Murphy, J.M.2
  • 116
    • 77049109926 scopus 로고    scopus 로고
    • Chondrogenesis of adult stem cells from adipose tissue and bone marrow: Induction by growth factors and cartilage-derived matrix
    • Diekman BO, Rowland CR, Lennon DP, Caplan AI, Guilak F. Chondrogenesis of adult stem cells from adipose tissue and bone marrow: Induction by growth factors and cartilage-derived matrix. Tissue Eng Part A 2010; 16(2): 523-33.
    • (2010) Tissue Eng Part A , vol.16 , Issue.2 , pp. 523-533
    • Diekman, B.O.1    Rowland, C.R.2    Lennon, D.P.3    Caplan, A.I.4    Guilak, F.5
  • 117
    • 85018269361 scopus 로고    scopus 로고
    • Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis
    • Yubo M, Yanyan L, Li L, Tao S, Bo L, Lin C. Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis. PLOS One 2017; 12(4): e0175449.
    • (2017) PLOS One , vol.12 , Issue.4
    • Yubo, M.1    Yanyan, L.2    Li, L.3    Tao, S.4    Bo, L.5    Lin, C.6
  • 118
    • 84971003210 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy in the treatment of osteoarthritis: Reparative pathways, safety and efficacy-a review
    • Freitag J, Bates D, Boyd R, Shah K, Barnard A, Huguenin L, et al. Mesenchymal stem cell therapy in the treatment of osteoarthritis: Reparative pathways, safety and efficacy-a review. BMC Muscu-loskelet Disord. 2016; 17: 230.
    • (2016) BMC Muscu-Loskelet Disord , vol.17 , pp. 230
    • Freitag, J.1    Bates, D.2    Boyd, R.3    Shah, K.4    Barnard, A.5    Huguenin, L.6
  • 119
    • 84898944698 scopus 로고    scopus 로고
    • Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof-of-concept clinical trial
    • Jo CH, Lee YG, Shin WH, Kim H, Chai JW, Jeong EC, et al. Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof-of-concept clinical trial. Stem Cells 2014; 32(5):1254-66.
    • (2014) Stem Cells , vol.32 , Issue.5 , pp. 1254-1266
    • Jo, C.H.1    Lee, Y.G.2    Shin, W.H.3    Kim, H.4    Chai, J.W.5    Jeong, E.C.6
  • 120
    • 84857047378 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease
    • Liang J, Zhang H, Wang D, Feng X, Wang H, Hua B, et al. Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease Gut 2012; 61: 468-9.
    • (2012) Gut , vol.61 , pp. 468-469
    • Liang, J.1    Zhang, H.2    Wang, D.3    Feng, X.4    Wang, H.5    Hua, B.6
  • 122
    • 85017634801 scopus 로고    scopus 로고
    • Efficacy of stem cells on periodontal regeneration: Systematic review of pre-clinical studies
    • Tassi SA, Sergio NZ, Misawa MYO, Villar CC. Efficacy of stem cells on periodontal regeneration: Systematic review of pre-clinical studies. J Periodontal Res 2017; 52(5): 793-812.
    • (2017) J Periodontal Res , vol.52 , Issue.5 , pp. 793-812
    • Tassi, S.A.1    Sergio, N.Z.2    Misawa, M.Y.O.3    Villar, C.C.4
  • 123
    • 0015978202 scopus 로고
    • Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection
    • Myers WC, Fountain SB. Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection. Oral Surg Oral Med Oral Pathol 1974; 37(3): 441-50.
    • (1974) Oral Surg Oral Med Oral Pathol , vol.37 , Issue.3 , pp. 441-450
    • Myers, W.C.1    Fountain, S.B.2
  • 125
    • 78049261005 scopus 로고    scopus 로고
    • Application of induced pluripotent stem (IPS) cells in periodontal tissue regeneration
    • Duan X, Tu Q, Zhang J, Ye J, Sommer C, Mostoslavsky G, et al. Application of induced pluripotent stem (iPS) cells in periodontal tissue regeneration. J Cell Physiol 2011; 226(1): 150-7.
    • (2011) J Cell Physiol , vol.226 , Issue.1 , pp. 150-157
    • Duan, X.1    Tu, Q.2    Zhang, J.3    Ye, J.4    Sommer, C.5    Mostoslavsky, G.6
  • 126
    • 84941420474 scopus 로고    scopus 로고
    • Differentiation of mouse iPS cells into ameloblast-like cells in cultures using medium conditioned by epithelial cell rests of Malassez and gelatin-coated dishes
    • Yoshida K, Sato J, Takai R, Uehara O, Kurashige Y, Nishimura M, et al. Differentiation of mouse iPS cells into ameloblast-like cells in cultures using medium conditioned by epithelial cell rests of Malassez and gelatin-coated dishes. Med Mol Morphol 2015; 48(3): 138-45.
    • (2015) Med Mol Morphol , vol.48 , Issue.3 , pp. 138-145
    • Yoshida, K.1    Sato, J.2    Takai, R.3    Uehara, O.4    Kurashige, Y.5    Nishimura, M.6
  • 127
    • 85038916462 scopus 로고    scopus 로고
    • Stem cell therapy for inflammatory bowel disease
    • Lightner AL. Stem cell therapy for inflammatory bowel disease. Clin Transl Gastroenterol (2017); 8: e82.
    • (2017) Clin Transl Gastroenterol , vol.8 , pp. 82
    • Lightner, A.L.1
  • 130
    • 85052326470 scopus 로고    scopus 로고
    • Function and therapeutic potential of mesenchymal stem cells in atherosclerosis
    • Li F, Guo X, Chen SY. Function and therapeutic potential of mesenchymal stem cells in atherosclerosis. Front Cardiovasc Med. 2017; 4: 32.
    • (2017) Front Cardiovasc Med , vol.4 , pp. 32
    • Li, F.1    Guo, X.2    Chen, S.Y.3
  • 131
    • 84870362545 scopus 로고    scopus 로고
    • Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice
    • Sun YQ, Deng MX, He J, Zeng QX, Wen W, Wong DS, et al. Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice. Stem Cells 2012; 30(12): 2692-9.
    • (2012) Stem Cells , vol.30 , Issue.12 , pp. 2692-2699
    • Sun, Y.Q.1    Deng, M.X.2    He, J.3    Zeng, Q.X.4    Wen, W.5    Wong, D.S.6
  • 132
    • 85030470788 scopus 로고    scopus 로고
    • Effects of human mesenchymal stem cells on airway inflammation in allergic asthma mice and the underlying mechanism
    • Ren NN, Chen HJ, Chen QL, Eileen J, An YG, Lin Y. Effects of human mesenchymal stem cells on airway inflammation in allergic asthma mice and the underlying mechanism. Zhonghua Yi Xue Za Zhi. 2017; 97(34): 2697-702.
    • (2017) Zhonghua Yi Xue Za Zhi , vol.97 , Issue.34 , pp. 2697-2702
    • Ren, N.N.1    Chen, H.J.2    Chen, Q.L.3    Eileen, J.4    An, Y.G.5    Lin, Y.6
  • 133
    • 85019062134 scopus 로고    scopus 로고
    • Immunologic regulatory effects of human umbilical cord blood-derived mesenchymal stem cells in a murine ovalbumin asthma model
    • Kang SY, Park DE, Song WJ, Bae BR, Lee JW, Sohn KH, et al. Immunologic regulatory effects of human umbilical cord blood-derived mesenchymal stem cells in a murine ovalbumin asthma model. Clin Exp Allergy 2017; 47(7): 937-45.
    • (2017) Clin Exp Allergy , vol.47 , Issue.7 , pp. 937-945
    • Kang, S.Y.1    Park, D.E.2    Song, W.J.3    Bae, B.R.4    Lee, J.W.5    Sohn, K.H.6
  • 134
    • 84982803315 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stem cells can mitigate oxidative stress and inflammation process in human mustard lung
    • Nejad-Moghaddam A, Ajdary S, Tahmasbpour E, Rad FR, Panahi Y, Ghanei M. Immunomodulatory properties of mesenchymal stem cells can mitigate oxidative stress and inflammation process in human mustard lung. Biochem Genet. 2016; 54: 769.
    • (2016) Biochem Genet , vol.54 , pp. 769
    • Nejad-Moghaddam, A.1    Ajdary, S.2    Tahmasbpour, E.3    Rad, F.R.4    Panahi, Y.5    Ghanei, M.6
  • 135
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, Dzau V. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 2008; 103(11): 1204-19.
    • (2008) Circ Res , vol.103 , Issue.11 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.4
  • 136
    • 84892394309 scopus 로고    scopus 로고
    • Mesenchymal Stem Cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture
    • Oliveira-Sales EB, Maquigussa E, Semedo P, Pereira LG, Ferreira VM, Câmara NO, et al. Mesenchymal Stem Cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture. PLOS One. 2013; 8(11): e78464.
    • (2013) PLOS One , vol.8 , Issue.11
    • Oliveira-Sales, E.B.1    Maquigussa, E.2    Semedo, P.3    Pereira, L.G.4    Ferreira, V.M.5    Câmara, N.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.