메뉴 건너뛰기




Volumn 62, Issue 8, 2018, Pages

Clonal background, resistance gene profile, and porin gene mutations modulate in vitro susceptibility to imipenem-relebactam in diverse enterobacteriaceae

Author keywords

Carbapenem resistance; Enterobacteriaceae; Imipenem relebactam

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE KPC 2; BETA LACTAMASE KPC 3; BETA LACTAMASE KPC 4; BETA LACTAMASE NDM 1; CARBAPENEMASE; CILASTATIN PLUS IMIPENEM; IMIPENEM; PORIN; RELEBACTAM; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; AZABICYCLO DERIVATIVE; BACTERIAL PROTEIN; MK-7655;

EID: 85052021811     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00573-18     Document Type: Article
Times cited : (34)

References (40)
  • 2
    • 84984893630 scopus 로고    scopus 로고
    • The global epidemiology of carbapenemase-producing Enterobacteriaceae
    • van Duin D, Doi Y. 2017. The global epidemiology of carbapenemase-producing Enterobacteriaceae. Virulence 8:460–469. https://doi.org/10.1080/21505594.2016.1222343.
    • (2017) Virulence , vol.8 , pp. 460-469
    • van Duin, D.1    Doi, Y.2
  • 3
    • 84979708915 scopus 로고    scopus 로고
    • Role of newer and re-emerging older agents in the treatment of infections caused by carbapenem-resistant Enterobacteriaceae
    • Thaden JT, Pogue JM, Kaye KS. 2017. Role of newer and re-emerging older agents in the treatment of infections caused by carbapenem-resistant Enterobacteriaceae. Virulence 8:403–416. https://doi.org/10.1080/21505594.2016.1207834.
    • (2017) Virulence , vol.8 , pp. 403-416
    • Thaden, J.T.1    Pogue, J.M.2    Kaye, K.S.3
  • 5
    • 84888787952 scopus 로고    scopus 로고
    • Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa
    • Livermore DM, Warner M, Mushtaq S. 2013. Activity of MK-7655 combined with imipenem against Enterobacteriaceae and Pseudomonas aeruginosa. J Antimicrob Chemother 68:2286–2290. https://doi.org/10.1093/jac/dkt178.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2286-2290
    • Livermore, D.M.1    Warner, M.2    Mushtaq, S.3
  • 7
    • 85019660287 scopus 로고    scopus 로고
    • In vitro activity of imipenem-relebactam against Gram-negative ESKAPE pathogens isolated by clinical laboratories in the United States in 2015 (results from the SMART global surveillance program)
    • Lob SH, Hackel MA, Kazmierczak KM, Young K, Motyl MR, Karlowsky JA, Sahm DF. 2017. In vitro activity of imipenem-relebactam against Gram-negative ESKAPE pathogens isolated by clinical laboratories in the United States in 2015 (results from the SMART global surveillance program). Antimicrob Agents Chemother 61:e02209-16. https://doi.org/10.1128/AAC.02209-16.
    • (2017) Antimicrob Agents Chemother , vol.61 , pp. e02209-e02216
    • Lob, S.H.1    Hackel, M.A.2    Kazmierczak, K.M.3    Young, K.4    Motyl, M.R.5    Karlowsky, J.A.6    Sahm, D.F.7
  • 8
    • 85014776176 scopus 로고    scopus 로고
    • In vitro activity of imipenem-relebactam against gram-negative bacilli isolated from patients with lower respiratory tract infections in the United States in 2015—results from the SMART global surveillance program
    • Lob SH, Hackel MA, Kazmierczak KM, Hoban DJ, Young K, Motyl MR, Karlowsky JA, Sahm DF. 2017. In vitro activity of imipenem-relebactam against gram-negative bacilli isolated from patients with lower respiratory tract infections in the United States in 2015—results from the SMART global surveillance program. Diagn Microbiol Infect Dis 88: 171–176. https://doi.org/10.1016/j.diagmicrobio.2017.02.018.
    • (2017) Diagn Microbiol Infect Dis , vol.88 , pp. 171-176
    • Lob, S.H.1    Hackel, M.A.2    Kazmierczak, K.M.3    Hoban, D.J.4    Young, K.5    Motyl, M.R.6    Karlowsky, J.A.7    Sahm, D.F.8
  • 9
    • 85028404107 scopus 로고    scopus 로고
    • Identifying spectra of activity and therapeutic niches for ceftazidime-avibactam and imipenem-relebactam against carbapenem-resistant Enterobacteriaceae
    • Haidar G, Clancy CJ, Chen L, Samanta P, Shields RK, Kreiswirth BN, Nguyen MH. 2017. Identifying spectra of activity and therapeutic niches for ceftazidime-avibactam and imipenem-relebactam against carbapenem-resistant Enterobacteriaceae. Antimicrob Agents Chemother 61:e00642-17. https://doi.org/10.1128/AAC.00642-17.
    • (2017) Antimicrob Agents Chemother , vol.61 , pp. e00642-e00717
    • Haidar, G.1    Clancy, C.J.2    Chen, L.3    Samanta, P.4    Shields, R.K.5    Kreiswirth, B.N.6    Nguyen, M.H.7
  • 10
    • 84946567642 scopus 로고    scopus 로고
    • A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens
    • Bush K. 2015. A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents 46:483–493. https://doi.org/10.1016/j.ijantimicag.2015.08.011.
    • (2015) Int J Antimicrob Agents , vol.46 , pp. 483-493
    • Bush, K.1
  • 11
    • 84940852196 scopus 로고    scopus 로고
    • Genomically informed surveillance for carbapenem-resistant Enterobacteriaceae in a health care system
    • Pecora ND, Li N, Allard M, Li C, Albano E, Delaney M, Dubois A, Onder-donk AB, Bry L. 2015. Genomically informed surveillance for carbapenem-resistant Enterobacteriaceae in a health care system. mBio 6:e01030. https://doi.org/10.1128/mBio.01030-15.
    • (2015) mBio , vol.6 , pp. e01030
    • Pecora, N.D.1    Li, N.2    Allard, M.3    Li, C.4    Albano, E.5    Delaney, M.6    Dubois, A.7    Onder-Donk, A.B.8    Bry, L.9
  • 13
    • 84982221181 scopus 로고    scopus 로고
    • Evidence from a New York City hospital of rising incidence of genetically diverse carbapenem-resistant Enterobacter cloacae and dominance of ST171, 2007–14
    • Gomez-Simmonds A, Hu Y, Sullivan SB, Wang Z, Whittier S, Uhlemann AC. 2016. Evidence from a New York City hospital of rising incidence of genetically diverse carbapenem-resistant Enterobacter cloacae and dominance of ST171, 2007–14. J Antimicrob Chemother 71:2351–2353. https://doi.org/10.1093/jac/dkw132.
    • (2016) J Antimicrob Chemother , vol.71 , pp. 2351-2353
    • Gomez-Simmonds, A.1    Hu, Y.2    Sullivan, S.B.3    Wang, Z.4    Whittier, S.5    Uhlemann, A.C.6
  • 14
    • 85007569961 scopus 로고    scopus 로고
    • Comprehensive genome analysis of carbapenemase-producing Enterobacter spp.: New insights into phylogeny, population structure, and resistance mechanisms
    • Chavda KD, Chen L, Fouts DE, Sutton G, Brinkac L, Jenkins SG, Bonomo RA, Adams MD, Kreiswirth BN. 2016. Comprehensive genome analysis of carbapenemase-producing Enterobacter spp.: new insights into phylogeny, population structure, and resistance mechanisms. mBio 7:e02093-16. https://doi.org/10.1128/mBio.02093-16.
    • (2016) mBio , vol.7 , pp. e02093-e02116
    • Chavda, K.D.1    Chen, L.2    Fouts, D.E.3    Sutton, G.4    Brinkac, L.5    Jenkins, S.G.6    Bonomo, R.A.7    Adams, M.D.8    Kreiswirth, B.N.9
  • 15
    • 85018629113 scopus 로고    scopus 로고
    • Carbapenem-resistant Enterobacter cloacae in patients from the US Veterans Health Administration, 2006–2015
    • Wilson BM, El Chakhtoura NG, Patel S, Saade E, Donskey CJ, Bonomo RA, Perez F. 2017. Carbapenem-resistant Enterobacter cloacae in patients from the US Veterans Health Administration, 2006–2015. Emerg Infect Dis 23:878–880. https://doi.org/10.3201/eid2305.162034.
    • (2017) Emerg Infect Dis , vol.23 , pp. 878-880
    • Wilson, B.M.1    El Chakhtoura, N.G.2    Patel, S.3    Saade, E.4    Donskey, C.J.5    Bonomo, R.A.6    Perez, F.7
  • 16
    • 85014572665 scopus 로고    scopus 로고
    • Therapeutic options for carbapenem-resistant Enterobacteriaceae infections
    • Trecarichi EM, Tumbarello M. 2017. Therapeutic options for carbapenem-resistant Enterobacteriaceae infections. Virulence 8:470–484. https://doi.org/10.1080/21505594.2017.1292196.
    • (2017) Virulence , vol.8 , pp. 470-484
    • Trecarichi, E.M.1    Tumbarello, M.2
  • 17
    • 0031892006 scopus 로고    scopus 로고
    • Contribution of overproduced chromosomal beta-lactamase and defective outer membrane porins to resistance to extended-spectrum beta-lactam antibiotics in Serratia marcescens
    • Weindorf H, Schmidt H, Martin HH. 1998. Contribution of overproduced chromosomal beta-lactamase and defective outer membrane porins to resistance to extended-spectrum beta-lactam antibiotics in Serratia marcescens. J Antimicrob Chemother 41:189–195. https://doi.org/10.1093/jac/41.2.189.
    • (1998) J Antimicrob Chemother , vol.41 , pp. 189-195
    • Weindorf, H.1    Schmidt, H.2    Martin, H.H.3
  • 18
    • 78649654934 scopus 로고    scopus 로고
    • Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss
    • Suh B, Bae IK, Kim J, Jeong SH, Yong D, Lee K. 2010. Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss. Antimicrob Agents Chemother 54:5057–5061. https://doi.org/10.1128/AAC.00768-10.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5057-5061
    • Suh, B.1    Bae, I.K.2    Kim, J.3    Jeong, S.H.4    Yong, D.5    Lee, K.6
  • 19
    • 85019688988 scopus 로고    scopus 로고
    • Piperacillin-tazobactam versus other antibacterial agents for treatment of bloodstream infections due to AmpC -lactamase-producing Enterobacteriaceae
    • Cheng L, Nelson BC, Mehta M, Seval N, Park S, Giddins MJ, Shi Q, Whittier S, Gomez-Simmonds A, Uhlemann AC. 2017. Piperacillin-tazobactam versus other antibacterial agents for treatment of bloodstream infections due to AmpC -lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother 61:e00276-17. https://doi.org/10.1128/AAC.00276-17.
    • (2017) Antimicrob Agents Chemother , vol.61 , pp. e00276-e00317
    • Cheng, L.1    Nelson, B.C.2    Mehta, M.3    Seval, N.4    Park, S.5    Giddins, M.J.6    Shi, Q.7    Whittier, S.8    Gomez-Simmonds, A.9    Uhlemann, A.C.10
  • 23
    • 84997002173 scopus 로고    scopus 로고
    • Ceftazidime/avibactam and ceftolozane/ tazobactam: Second-generation beta-lactam/beta-lactamase inhibitor combinations
    • van Duin D, Bonomo RA. 2016. Ceftazidime/avibactam and ceftolozane/ tazobactam: second-generation beta-lactam/beta-lactamase inhibitor combinations. Clin Infect Dis 63:234–241. https://doi.org/10.1093/cid/ciw243.
    • (2016) Clin Infect Dis , vol.63 , pp. 234-241
    • van Duin, D.1    Bonomo, R.A.2
  • 24
    • 85039424423 scopus 로고    scopus 로고
    • Ceftazidime-avibactam versus meropenem in nosocomial pneumonia, including ventilator-associated pneumonia (REPROVE): A randomised, double-blind, phase 3 non-inferiority trial
    • Torres A, Zhong N, Pachl J, Timsit JF, Kollef M, Chen Z, Song J, Taylor D, Laud PJ, Stone GG, Chow JW. 2018. Ceftazidime-avibactam versus meropenem in nosocomial pneumonia, including ventilator-associated pneumonia (REPROVE): a randomised, double-blind, phase 3 non-inferiority trial. Lancet Infect Dis 18:285–295. https://doi.org/10.1016/S1473-3099(17)30747-8.
    • (2018) Lancet Infect Dis , vol.18 , pp. 285-295
    • Torres, A.1    Zhong, N.2    Pachl, J.3    Timsit, J.F.4    Kollef, M.5    Chen, Z.6    Song, J.7    Taylor, D.8    Laud, P.J.9    Stone, G.G.10    Chow, J.W.11
  • 25
    • 84971578709 scopus 로고    scopus 로고
    • Efficacy and safety of ceftazidime-avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infection: Results from a randomized, controlled, double-blind, phase 3 program
    • Mazuski JE, Gasink LB, Armstrong J, Broadhurst H, Stone GG, Rank D, Llorens L, Newell P, Pachl J. 2016. Efficacy and safety of ceftazidime-avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infection: results from a randomized, controlled, double-blind, phase 3 program. Clin Infect Dis 62:1380–1389. https://doi.org/10.1093/cid/ciw133.
    • (2016) Clin Infect Dis , vol.62 , pp. 1380-1389
    • Mazuski, J.E.1    Gasink, L.B.2    Armstrong, J.3    Broadhurst, H.4    Stone, G.G.5    Rank, D.6    Llorens, L.7    Newell, P.8    Pachl, J.9
  • 26
    • 84963954564 scopus 로고    scopus 로고
    • Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): A randomised, pathogen-directed, phase 3 study
    • Carmeli Y, Armstrong J, Laud PJ, Newell P, Stone G, Wardman A, Gasink LB. 2016. Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study. Lancet Infect Dis 16:661–673. https://doi.org/10.1016/S1473-3099(16)30004-4.
    • (2016) Lancet Infect Dis , vol.16 , pp. 661-673
    • Carmeli, Y.1    Armstrong, J.2    Laud, P.J.3    Newell, P.4    Stone, G.5    Wardman, A.6    Gasink, L.B.7
  • 27
    • 85017371968 scopus 로고    scopus 로고
    • A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem for complicated intra-abdominal infections in hospitalised adults in Asia
    • Qin X, Tran BG, Kim MJ, Wang L, Nguyen DA, Chen Q, Song J, Laud PJ, Stone GG, Chow JW. 2017. A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem for complicated intra-abdominal infections in hospitalised adults in Asia. Int J Antimicrob Agents 49:579–588. https://doi.org/10.1016/j.ijantimicag.2017.01.010.
    • (2017) Int J Antimicrob Agents , vol.49 , pp. 579-588
    • Qin, X.1    Tran, B.G.2    Kim, M.J.3    Wang, L.4    Nguyen, D.A.5    Chen, Q.6    Song, J.7    Laud, P.J.8    Stone, G.G.9    Chow, J.W.10
  • 28
    • 84995390345 scopus 로고    scopus 로고
    • Ceftazidime-avibactam versus doripenem for the treatment of complicated urinary tract infections, including acute pyelonephritis: RECAPTURE, a phase 3 randomized trial program
    • Wagenlehner FM, Sobel JD, Newell P, Armstrong J, Huang X, Stone GG, Yates K, Gasink LB. 2016. Ceftazidime-avibactam versus doripenem for the treatment of complicated urinary tract infections, including acute pyelonephritis: RECAPTURE, a phase 3 randomized trial program. Clin Infect Dis 63:754–762. https://doi.org/10.1093/cid/ciw378.
    • (2016) Clin Infect Dis , vol.63 , pp. 754-762
    • Wagenlehner, F.M.1    Sobel, J.D.2    Newell, P.3    Armstrong, J.4    Huang, X.5    Stone, G.G.6    Yates, K.7    Gasink, L.B.8
  • 29
    • 85020131028 scopus 로고    scopus 로고
    • In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a phase 3 clinical trial programme for the treatment of complicated urinary tract infections
    • Stone GG, Bradford PA, Yates K, Newell P. 2017. In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a phase 3 clinical trial programme for the treatment of complicated urinary tract infections. J Antimicrob Chemother 72:1396–1399. https://doi.org/10.1093/jac/dkw561.
    • (2017) J Antimicrob Chemother , vol.72 , pp. 1396-1399
    • Stone, G.G.1    Bradford, P.A.2    Yates, K.3    Newell, P.4
  • 36
    • 0037721516 scopus 로고    scopus 로고
    • Multilocus sequence typing (MLST) of Escherichia coli O78 strains
    • Adiri RS, Gophna U, Ron EZ. 2003. Multilocus sequence typing (MLST) of Escherichia coli O78 strains. FEMS Microbiol Lett 222:199–203. https://doi.org/10.1016/S0378-1097(03)00295-7.
    • (2003) FEMS Microbiol Lett , vol.222 , pp. 199-203
    • Adiri, R.S.1    Gophna, U.2    Ron, E.Z.3
  • 37
    • 23744446161 scopus 로고    scopus 로고
    • Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates
    • Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S. 2005. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol 43:4178 – 4182. https://doi.org/10.1128/JCM.43.8.4178-4182.2005.
    • (2005) J Clin Microbiol , vol.43 , pp. 4178-4182
    • Diancourt, L.1    Passet, V.2    Verhoef, J.3    Grimont, P.A.4    Brisse, S.5
  • 38
    • 84878891677 scopus 로고    scopus 로고
    • Multilocus sequence typing (MLST) for characterization of Enterobacter cloacae
    • Miyoshi-Akiyama T, Hayakawa K, Ohmagari N, Shimojima M, Kirikae T. 2013. Multilocus sequence typing (MLST) for characterization of Enterobacter cloacae. PLoS One 8:e66358. https://doi.org/10.1371/journal.pone.0066358.
    • (2013) PLoS One , vol.8
    • Miyoshi-Akiyama, T.1    Hayakawa, K.2    Ohmagari, N.3    Shimojima, M.4    Kirikae, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.