Contribution of overproduced chromosomal β-lactamase and defective outer membrane porins to resistance to extended-spectrum β-lactam antibiotics in Serratia marcescens

Journal of Antimicrobial Chemotherapy

Volumn 41, Issue 2, 1998, Pages 189-195

  Weindorf, Herbert ^a   Schmidt, Herbert ^a   Martin, Hans H ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOTAXIME; CEFTAZIDIME; IMIPENEM; LATAMOXEF; PORIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL OUTER MEMBRANE; CHROMOSOME; CONTROLLED STUDY; ENZYME SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; SERRATIA MARCESCENS;

BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BETA-LACTAMS; CHROMOSOMES, BACTERIAL; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; PORINS; SERRATIA MARCESCENS;

EID: 0031892006     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/41.2.189     Document Type: Article

References (45)

1. Hechler, U., van den Weghe, M., Martin, H. H. & Frère, J. M. (1989). Overproduced β-lactamase and outer membrane barrier as resistance factors in Serratia marcescens highly resistant to β-lactamase-stable yS-lactam antibiotics. Journal of General Microbiology 135, 1275-90.
2. Gunkel, A. G., Hechler, U. & Martin, H. H. (1991). State of penicillin-binding-proteins and requirements for their bactericidal interaction with β-lactam antibiotics in Serratia marcescens highly resistant to extended spectrum β-lactams. Journal of General Microbiology 137,243-52.
3. Joris, B., De Meester, F., Galleni, M., Masson, S., Dusart, J., Frère, J. M. et al. (1986). Properties of a class C β-lactamase from Serratia marcescens. Biochemical Journal 239,581-6.
4. Bush, K., Jacoby, G. A. & Medeiros, A. A. (1995). A functional classification scheme for β-lactamases and its correlation with molecular structure. Antimicrobial Agents and Chemotherapy 39, 1211-33.
5. Lindberg, F., Lindquist, S. & Normark, S. (1987). Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii β-lactamase. Journal of Bacteriology 169,1923-8.
6. Lindquist, S., Galleni, M., Lindberg, F. & Normark, S. (1989). Signalling proteins in enterobacterial AmpC β-lactamase regulation. Molecular Microbiology 3,1091 -102.
7. Honoré, N., Nicolas, M. H. & Cole, S. T. (1989). Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer. Molecular Microbiology 3, 1121-30.
8. Normark, S., Bartowsky, E., Erickson, J., Jacobs, C., Lindberg. F., Lindquist, S. et al. (1994). Mechanisms of chromosomal β-lactamase induction in Gram-negative bacteria. In Bacterial Cell Wall (Ghuysen, J.M. & Hakenbeck, R., Eds), pp. 485-503. Elsevier Science, Amsterdam.
9. Höltje, J. V., Kopp, U., Ursinus, A. & vyiedemann, B. (1994). The negative regulator of β-lactamase induction, AmpD, is a N-acetyl-anhydromuramyl-L-alanine amidase. FEMS Microbiology Letters 122,159-64.
10. Jacobs, C., Joris, B., Jamin, M., Klarsov, K., Van Beeumen, J., Mengin-Lecreulx, D. et al. (1995). AmpD, essential for both β-lactamase regulation and cell wall recycling is a novel cytosolic N-acetyl muramyl-L-alanine amidase. Molecular Microbiology 15, 553-9.
11. Frère, J. M. (1989). Quantitative relationship between sensitivity to β-lactam antibiotics and β-lactamase production in Gram-negative bacteria. I. Steady state treatment. Biochemical Pharmacology 38,1415-26.
12. Frère, J. M., Joris, B., Crine, M. & Martin, H. H. (1989). Quantitative relationship between sensitivity to β-lactam antibiotics and β-lactamase production in Gram-negative bacteria. II. Nonsteady state treatment and progress curves. Biochemical Pharmacology38,1427-34.
13. Sawai, T., Hirano, S. & Yamaguchi, A. (1987). Repression of porin synthesis by salicylate in Escherichia coli, Klebsiella pneumoniae, and Serratia marcescens. FEMS Microbiology Letters 40, 233-7.
14. Puig, M., Fusté, C. & Vinas, M. (1993). Outer membrane proteins of Serratia marcescens. Canadian Journal of Microbiology 39,108-11.
15. Goldstein, F. W., Gutman, L., Williamson, R., Collatz, E. & Acar, J. F. (1983). In vivo and in vitro emergence of simultaneous resistance to both β-lactam and aminoglycoside antibiotics in a strain of Serratia marcescens. Annales de Microbiologie (Institut Pasteur) 134 A, 329-37.
16. Gutmann, L. & Chabbert, Y. A. (1984). Different mechanisms of resistance to latamoxef (moxalactam) in Serratia marcescens. Journal of Antimicrobial Chemotherapy 13,15-22.
17. Sanders, C. C. & Watanakunakorn, C. (1986). Emergence of resistance to β-lactams, aminoglycosides, and quinolones during combination therapy for infection due to Serratia marcescens. Journal of Infectious Diseases 153,617-19.
18. Piddock, L. J. V. & Traynor, E. A. (1991). β-Lactamase expression and outer membrane protein changes in cefpiromeresistant and ceftazidime-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy 28,209-219.
19. Hashizume, T., Sanada, M., Nakagawa, S. & Tanaka, N. (1993). Alteration in expression of Serratia marcescens porins associated with decreased outer membrane permeability. Journal of Antimicrobial Chemotherapy 31,21-8.
20. Malouin, F., Campbell, G. D., Halpenny, M., Becker, G. W. & Parr, T. R. (1990). Outer membrane and porin characteristics of Serratia marcescens grown in vitro and in rat intraperitoneal diffusion chambers. Infection and Immunity 58,1247-53.
21. Hutsul, J. A., Worobec, E., Parr, T. R. & Becker, G. W. (1993). Comparative analyses of Serratia spp. outer membrane porin proteins. Canadian Journal of Microbiology 39,442-7.
22. Hutsul, J. A. & Worobec, E. (1994). Molecular characterization of the 40 kDa OmpC-like porin from Serratia marcescens. Microbiologyl 140, 379-87.
23. Yoshimura, F. & Nikaido, H. (1985). Diffusion of β-lactam antibiotics through the porin channels of Escherichia coli K12. Antimicrobial Agents and Chemotherapy 27,84-92.
24. Miller, J. H. (1972). Experiments in Molecular Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
25. Mandel, M. & Higa, A. (1970). Calcium dependent bacteriophage DNA infection. Journal of Molecular Biology 53,159-62.
26. Lugtenberg, B., Meijers, J., Peters, R., van der Hoek, P. & van Alphen, L. (1975). Electrophoretic resolution of the 'major outer membrane protein1 of Escherichia coli K12 into four bands. FEBS-Letters58, 254-8.
27. Filip, C., Fletcher, G., Wulff, J. L. & Earhart, C. F. (1973). Solubilization of the cytoplasmic membrane of Escherichia coli by the ionic detergent sodium-lauryl sarcosinate. Journal of Bacteriology 115,717-22.
28. Neuhoff, V. (1990). Die kolloidale Coomassie-Blau-Färbung von Proteinen und Peptiden in Polyacrylamidgelen. Biological Chemistry Hoppe-Seyler 371,10-11.
29. Westermeier, R., Schickle, H., Thesseling, G. & Walter, W. W. (1988). Densitometrie von Gelektrophoresen. GIT Labor Medizin 4, 194-202.
30. Markwell, M. A. K., Hass, S. M., Bieber, L. L. & Tolbert, N. E. (1978). A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Analytical Biochemistry 87,206-10.
31. Traub, W. H., Spohr, M. & Bauer, D. (1983). Plasmidindependent resistance of 'grey' colony variants of a strain of Serratia marcescens resistant to amikacin, cefotaxime and lamoxactam. Chemotherapy 29,265-74.
32. Lugtenberg, B., Peters, R., Bernheimer, H. & Berendsen, W. (1976). Influence of cultural conditions and mutations on the composition of outer membrane proteins of Escherichia coli. Molecular and General Genetics 147,251-62.
33. Overbeeke, N. & Lugtenberg, B. (1980). Major outer membrane proteins of Escherichia coli strains of human origin. Journal of General Microbiology 121,373-80.
34. Beher, M. G., Schnaitman, C. A. & Pugsley, A. P. (1980). Major heat-modifiable outer membrane protein in Gram-negative bacteria: Comparison with the OmpA protein of Escherichia colt. Journal of Bacteriology 143,906-13.
35. Cole, S. T., Sonntag, I. & Henning U. (1982). Cloning and expression in Escherichia coli K12 of the genes for outer membrane protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens. Journal otBacteriology149,145-50.
36. Sonntag, l., Schwarz, H., Hirota, Y. & Henning, U. (1978). Cell envelope and shape of Escherichia coli: multiple mutants missing the outer membrane lipoprotein and other major outer membrane proteins. Journal of Bacteriology 136,280-5.
37. Sugawara, E. & Nikaido, H. (1992). Pore-forming activity of OmpA protein of Escherichia coli. Journal of Biological Chemistry, 267,2505-11.
38. Nakamura, K. & Mizushima, S. (1976). Effects of heating in dodecyl sulfate solution on the conformation and electrophoretic mobility of isolated major outer membrane? proteins of Escherichia coli K12. Journal of Biochemistry 80,1411-22.
39. van Alphen, W. & Lugtenberg, B. (1977). Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli. Journal of Bacteriology131,623-30.
40. Datz, M., Joris, B., Azab, A. M., Galleni, M., Van Beeumen, J., Frère, J. M. & Martin, H. H. (1994). A common system controls the induction of very different genes. The class-A β-lactamase of Proteus vulgaris and the enterobacterial class-C β-lactamase. European Journal of Biochemistry 226,149-57.
41. Kopp, U., Wiedemann, B., Lindquist, S. & Normark, S. (1993). Sequences of wild type and mutant ampD genes of Citrobacter freundii and Enterobacter cloacae. Antimicrobial Agents and Chemotherapy 37,224-8.
42. Stapleton, P., Shannon, K. & Phillips, I. (1995). DNA sequence differences of ampD mutants of Citrobacter freundii. Antimicrobial Agents and Chemotherapy 39,2494-8.
43. Lindquist, S., Weston-Hafer, K., Schmidt. H., Pul, C., Korfmann, G., Erickson, J. etal. (1993). AmpG, a signal transducer in chromosomal β-lactamase induction. Molecular Microbiology 9, 703-15.
44. Naas, T., Vandel, L, Sougakoff, W., Livermore, D. M. & Nordmann, P. (1994). Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A β-lactamase, Sme-1, from Serratia marcescens S6. Antimicrobial Agents and Chemotherapy 38,1262-70.
45. Osano, E., Arakawa, Y. S., Wacharotayankun, R., Ohta, M., Horii, T., Ito, H. et al. (1994). Molecular characterization of an enterobacterial metallo-β-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrobial Agents and Chemotherapy 38,71-8.