-
1
-
-
84873043409
-
Biochemical and functional characterization of a recombinant monomeric factor VIII-Fc fusion protein
-
Peters RT, Toby G, Lu Q, et al. Biochemical and functional characterization of a recombinant monomeric factor VIII-Fc fusion protein. J Thromb Haemost. 2013;11(1):132–141.
-
(2013)
J Thromb Haemost.
, vol.11
, Issue.1
, pp. 132-141
-
-
Peters, R.T.1
Toby, G.2
Lu, Q.3
-
2
-
-
84873625664
-
BAX 855, a PEGylated rFVIII product with prolonged half-life. Development, functional and structural characterisation
-
Turecek PL, Bossard MJ, Graninger M, et al. BAX 855, a PEGylated rFVIII product with prolonged half-life. Development, functional and structural characterisation. Hamostaseologie. 2012;32(S 01):S29–S38.
-
(2012)
Hamostaseologie.
, vol.32
, Issue.S 01
, pp. S29-S38
-
-
Turecek, P.L.1
Bossard, M.J.2
Graninger, M.3
-
3
-
-
84989837111
-
Pharmacokinetic drug evaluation of albutrepenonacog alfa (CSL654) for the treatment of hemophilia
-
Morfini M. Pharmacokinetic drug evaluation of albutrepenonacog alfa (CSL654) for the treatment of hemophilia. Expert Opin Drug Metab Toxicol. 2016;12(11):1359–1365.
-
(2016)
Expert Opin Drug Metab Toxicol.
, vol.12
, Issue.11
, pp. 1359-1365
-
-
Morfini, M.1
-
4
-
-
84889769562
-
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B
-
Powell JS, Pasi KJ, Ragni MV, et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med. 2013;369(24):2313–2323.
-
(2013)
N Engl J Med.
, vol.369
, Issue.24
, pp. 2313-2323
-
-
Powell, J.S.1
Pasi, K.J.2
Ragni, M.V.3
-
5
-
-
80052669248
-
Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B
-
Negrier C, Knobe K, Tiede A, et al. Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B. Blood. 2011;118(10):2695–2701.
-
(2011)
Blood.
, vol.118
, Issue.10
, pp. 2695-2701
-
-
Negrier, C.1
Knobe, K.2
Tiede, A.3
-
6
-
-
85040797644
-
Emicizumab-kxwh: first global approval
-
Scott LJ, Kim ES. Emicizumab-kxwh: first global approval. Drugs. 2018;78(2):269–274.
-
(2018)
Drugs.
, vol.78
, Issue.2
, pp. 269-274
-
-
Scott, L.J.1
Kim, E.S.2
-
7
-
-
85028497303
-
Emicizumab prophylaxis in hemophilia A with inhibitors
-
Oldenburg J, Mahlangu JN, Kim B, et al. Emicizumab prophylaxis in hemophilia A with inhibitors. N Engl J Med. 2017;377(9):809–818.
-
(2017)
N Engl J Med.
, vol.377
, Issue.9
, pp. 809-818
-
-
Oldenburg, J.1
Mahlangu, J.N.2
Kim, B.3
-
8
-
-
84928764693
-
Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial
-
Chowdary P, Lethagen S, Friedrich U, et al. Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial. J Thromb Haemost. 2015;13(5):743–754.
-
(2015)
J Thromb Haemost.
, vol.13
, Issue.5
, pp. 743-754
-
-
Chowdary, P.1
Lethagen, S.2
Friedrich, U.3
-
9
-
-
85028558994
-
Targeting of antithrombin in Hemophilia A or B with RNAi therapy
-
Pasi KJ, Rangarajan S, Georgiev P, et al. Targeting of antithrombin in Hemophilia A or B with RNAi therapy. N Engl J Med. 2017;377(9):819–828.
-
(2017)
N Engl J Med.
, vol.377
, Issue.9
, pp. 819-828
-
-
Pasi, K.J.1
Rangarajan, S.2
Georgiev, P.3
-
10
-
-
84960106888
-
Safety, stability and pharmacokinetic properties of (super)Factor Va, a novel engineered coagulation Factor V for treatment of severe bleeding
-
Gale AJ, Bhat V, Pellequer JL, et al. Safety, stability and pharmacokinetic properties of (super)Factor Va, a novel engineered coagulation Factor V for treatment of severe bleeding. Pharm Res. 2016;33(6):1517–1526.
-
(2016)
Pharm Res.
, vol.33
, Issue.6
, pp. 1517-1526
-
-
Gale, A.J.1
Bhat, V.2
Pellequer, J.L.3
-
11
-
-
33748790682
-
Factor VIII and thrombin generation assays: relevance to pharmacokinetic studies in haemophilia A
-
Barrowcliffe TW. Factor VIII and thrombin generation assays: relevance to pharmacokinetic studies in haemophilia A. Haemophilia. 2006;12(s4):23–29.
-
(2006)
Haemophilia.
, vol.12
, Issue.s4
, pp. 23-29
-
-
Barrowcliffe, T.W.1
-
12
-
-
78649982927
-
Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype
-
Oldenburg J, Pavlova A. Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype. Hamostaseologie. 2010;30(04):207–211.
-
(2010)
Hamostaseologie.
, vol.30
, Issue.4
, pp. 207-211
-
-
Oldenburg, J.1
Pavlova, A.2
-
13
-
-
0347043611
-
A multi-centre collaborative study on the potency estimation of ReFacto
-
Hubbard AR, Sands D, Sandberg E, et al. A multi-centre collaborative study on the potency estimation of ReFacto. Thromb Haemost. 2003;90(6):1088–1093.
-
(2003)
Thromb Haemost.
, vol.90
, Issue.6
, pp. 1088-1093
-
-
Hubbard, A.R.1
Sands, D.2
Sandberg, E.3
-
14
-
-
84976209150
-
A critical appraisal of one-stage and chromogenic assays of factor VIII activity
-
Peyvandi F, Oldenburg J, Friedman KD. A critical appraisal of one-stage and chromogenic assays of factor VIII activity. J Thromb Haemost. 2016;14(2):248–261.
-
(2016)
J Thromb Haemost.
, vol.14
, Issue.2
, pp. 248-261
-
-
Peyvandi, F.1
Oldenburg, J.2
Friedman, K.D.3
-
15
-
-
84957595385
-
Global assays in hemophilia
-
Chitlur M, Young G. Global assays in hemophilia. Semin Hematol. 2016;53(1):40–45.
-
(2016)
Semin Hematol.
, vol.53
, Issue.1
, pp. 40-45
-
-
Chitlur, M.1
Young, G.2
-
16
-
-
85051726759
-
-
Hemlibra (emicizumab-kxwh). Package insert. Genentech, Inc, South San Francisco, CA;
-
Hemlibra (emicizumab-kxwh). Package insert. Genentech, Inc, South San Francisco, CA; 2017.
-
(2017)
-
-
-
18
-
-
11044238614
-
Monitoring haemophilia severity and treatment: new or old laboratory tests?
-
Barrowcliffe TW. Monitoring haemophilia severity and treatment: new or old laboratory tests?. Haemophilia. 2004;10(Suppl 4):109–114.
-
(2004)
Haemophilia.
, vol.10
, pp. 109-114
-
-
Barrowcliffe, T.W.1
-
19
-
-
0025847974
-
The design and analysis of half-life and recovery studies for factor VIII and factor IX. Factor VIII/Factor IX Scientific and Standardization Committee of the International Society for Thrombosis and Haemostasis
-
Morfini M, Lee M, Messori A. The design and analysis of half-life and recovery studies for factor VIII and factor IX. Factor VIII/Factor IX Scientific and Standardization Committee of the International Society for Thrombosis and Haemostasis. Thromb Haemost. 1991;66(3):384–386.
-
(1991)
Thromb Haemost.
, vol.66
, Issue.3
, pp. 384-386
-
-
Morfini, M.1
Lee, M.2
Messori, A.3
-
20
-
-
85037046378
-
Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH
-
Iorio A, Blanchette V, Blatny J, et al. Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH. J Thromb Haemost. 2017;15(12):2461–2465.
-
(2017)
J Thromb Haemost.
, vol.15
, Issue.12
, pp. 2461-2465
-
-
Iorio, A.1
Blanchette, V.2
Blatny, J.3
-
21
-
-
85057100502
-
Focusing in on use of pharmacokinetic profiles in routine hemophilia care
-
Croteau SE, Callaghan MU, Davis J, et al. Focusing in on use of pharmacokinetic profiles in routine hemophilia care. Res Pract Thromb Haemost. 2018;93:1–8.
-
(2018)
Res Pract Thromb Haemost
, vol.93
, pp. 1-8
-
-
Croteau, S.E.1
Callaghan, M.U.2
Davis, J.3
-
23
-
-
84931956043
-
Potency determination of factor VIII and factor IX for new product labelling and postinfusion testing: challenges for caregivers and regulators
-
Dodt J, Hubbard AR, Wicks SJ, et al. Potency determination of factor VIII and factor IX for new product labelling and postinfusion testing: challenges for caregivers and regulators. Haemophilia. 2015;21(4):543–549.
-
(2015)
Haemophilia.
, vol.21
, Issue.4
, pp. 543-549
-
-
Dodt, J.1
Hubbard, A.R.2
Wicks, S.J.3
-
24
-
-
85051729020
-
-
National Hemophilia Foundation Medical and Science Advisory Committee Statement Regarding Use of Various Clotting Factor Assays to Monitor Factor Replacement Therapy., MASAC Document #228.
-
National Hemophilia Foundation Medical and Science Advisory Committee Statement Regarding Use of Various Clotting Factor Assays to Monitor Factor Replacement Therapy. 2014;MASAC Document #228.
-
(2014)
-
-
-
25
-
-
50449147939
-
Effect of antihemophilic factor on one-stage clotting tests; a presumptive test for hemophilia and a simple one-stage antihemophilic factor assy procedure
-
Langdell RD, Wagner RH, Brinkhous KM. Effect of antihemophilic factor on one-stage clotting tests; a presumptive test for hemophilia and a simple one-stage antihemophilic factor assy procedure. J Lab Clin Med. 1953;41:637–647.
-
(1953)
J Lab Clin Med.
, vol.41
, pp. 637-647
-
-
Langdell, R.D.1
Wagner, R.H.2
Brinkhous, K.M.3
-
26
-
-
0021752980
-
Methodology of the one-stage assay of Factor VIII (VIII:C)
-
Over J. Methodology of the one-stage assay of Factor VIII (VIII:C). Scand J Haematol Suppl. 1984;41:13–24.
-
(1984)
Scand J Haematol Suppl.
, vol.41
, pp. 13-24
-
-
Over, J.1
-
28
-
-
84872265901
-
Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis
-
Mackie I, Cooper P, Lawrie A, et al. Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis. Int Jnl Lab Hem. 2013;35(1):1–13.
-
(2013)
Int Jnl Lab Hem.
, vol.35
, Issue.1
, pp. 1-13
-
-
Mackie, I.1
Cooper, P.2
Lawrie, A.3
-
29
-
-
0002641258
-
The assay of antihaemophilic-globulin activity
-
Biggs R, Eveling J, Richards G. The assay of antihaemophilic-globulin activity. Br J Haematol. 1955;1(1):20–34.
-
(1955)
Br J Haematol.
, vol.1
, Issue.1
, pp. 20-34
-
-
Biggs, R.1
Eveling, J.2
Richards, G.3
-
30
-
-
18244425992
-
Proceedings: Automated techniques for estimating factor VIII levels in concentrate preparations
-
Seghatchian MJ, Miller-Anderson M, Howarth DJ, et al. Proceedings: Automated techniques for estimating factor VIII levels in concentrate preparations. Thromb Diath Haemorrh. 1975;34(2):611.
-
(1975)
Thromb Diath Haemorrh.
, vol.34
, Issue.2
, pp. 611
-
-
Seghatchian, M.J.1
Miller-Anderson, M.2
Howarth, D.J.3
-
32
-
-
0021248074
-
Assay of factor VIII:C with a chromogenic substrate
-
Rosen S. Assay of factor VIII:C with a chromogenic substrate. Scand J Haematol Suppl. 1984;40:139–145.
-
(1984)
Scand J Haematol Suppl.
, vol.40
, pp. 139-145
-
-
Rosen, S.1
-
33
-
-
0037810809
-
Standardization of FVIII & FIX assays
-
Barrowcliffe TW. Standardization of FVIII & FIX assays. Haemophilia. 2003;9(4):397–402.
-
(2003)
Haemophilia.
, vol.9
, Issue.4
, pp. 397-402
-
-
Barrowcliffe, T.W.1
-
34
-
-
84886736407
-
Main considerable factors for correct laboratory test interpretation under DOA treatment
-
Mani H, Lindhoff-Last E. Main considerable factors for correct laboratory test interpretation under DOA treatment. Thrombosis J. 2013;11(1):22.
-
(2013)
Thrombosis J.
, vol.11
, Issue.1
, pp. 22
-
-
Mani, H.1
Lindhoff-Last, E.2
-
35
-
-
0022341515
-
Clinical application of a chromogenic substrate method for determination of factor VIII activity
-
Rosen S, Andersson M, Blomback M, et al. Clinical application of a chromogenic substrate method for determination of factor VIII activity. Thromb Haemost. 1985;54(4):818–823.
-
(1985)
Thromb Haemost.
, vol.54
, Issue.4
, pp. 818-823
-
-
Rosen, S.1
Andersson, M.2
Blomback, M.3
-
37
-
-
0025687057
-
Preparation of factor-VIII-depleted plasma with antibodies and its use for the assay of factor VIII
-
Rothschild C, Amiral J, Adam M, et al. Preparation of factor-VIII-depleted plasma with antibodies and its use for the assay of factor VIII. Haemostasis. 1990;20(6):321–328.
-
(1990)
Haemostasis.
, vol.20
, Issue.6
, pp. 321-328
-
-
Rothschild, C.1
Amiral, J.2
Adam, M.3
-
38
-
-
85041318196
-
International comparative field study evaluating the assay performance of AFSTYLA in plasma samples at clinical hemostasis laboratories
-
St Ledger K, Feussner A, Kalina U, et al. International comparative field study evaluating the assay performance of AFSTYLA in plasma samples at clinical hemostasis laboratories. J Thromb Haemost. 2018;16(3):555–564.
-
(2018)
J Thromb Haemost.
, vol.16
, Issue.3
, pp. 555-564
-
-
St Ledger, K.1
Feussner, A.2
Kalina, U.3
-
39
-
-
84894260830
-
Comparative field study evaluating the activity of recombinant factor VIII Fc fusion protein in plasma samples at clinical haemostasis laboratories
-
Sommer JM, Moore N, McGuffie-Valentine B, et al. Comparative field study evaluating the activity of recombinant factor VIII Fc fusion protein in plasma samples at clinical haemostasis laboratories. Haemophilia. 2014;20(2):294–300.
-
(2014)
Haemophilia.
, vol.20
, Issue.2
, pp. 294-300
-
-
Sommer, J.M.1
Moore, N.2
McGuffie-Valentine, B.3
-
40
-
-
84962877636
-
BAY 81–8973, a full-length recombinant factor VIII: results from an International comparative laboratory field study
-
Kitchen S, Beckmann H, Katterle Y, et al. BAY 81–8973, a full-length recombinant factor VIII: results from an International comparative laboratory field study. Haemophilia. 2016;22(3):e192–e199.
-
(2016)
Haemophilia.
, vol.22
, Issue.3
, pp. e192-e199
-
-
Kitchen, S.1
Beckmann, H.2
Katterle, Y.3
-
41
-
-
79959505463
-
International comparative field study of N8 evaluating factor VIII assay performance
-
Viuff D, Barrowcliffe T, Saugstrup T, et al. International comparative field study of N8 evaluating factor VIII assay performance. Haemophilia. 2011;17(4):695–702.
-
(2011)
Haemophilia.
, vol.17
, Issue.4
, pp. 695-702
-
-
Viuff, D.1
Barrowcliffe, T.2
Saugstrup, T.3
-
42
-
-
85013149291
-
Measuring FVIII activity of glycopegylated recombinant factor VIII, N8-GP, with commercially available one-stage clotting and chromogenic assay kits: a two-centre study
-
Hillarp A, Bowyer A, Ezban M, et al. Measuring FVIII activity of glycopegylated recombinant factor VIII, N8-GP, with commercially available one-stage clotting and chromogenic assay kits: a two-centre study. Haemophilia. 2017;23(3):458–465.
-
(2017)
Haemophilia.
, vol.23
, Issue.3
, pp. 458-465
-
-
Hillarp, A.1
Bowyer, A.2
Ezban, M.3
-
43
-
-
80051963635
-
The use of the new ReFacto AF Laboratory Standard allows reliable measurement of FVIII:C levels in ReFacto AF mock plasma samples by a one-stage clotting assay
-
Pouplard C, Caron C, Aillaud MF, et al. The use of the new ReFacto AF Laboratory Standard allows reliable measurement of FVIII:C levels in ReFacto AF mock plasma samples by a one-stage clotting assay. Haemophilia. 2011;17:e958–962.
-
(2011)
Haemophilia.
, vol.17
, pp. 958-962
-
-
Pouplard, C.1
Caron, C.2
Aillaud, M.F.3
-
44
-
-
84908528868
-
Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity
-
Sommer JM, Buyue Y, Bardan S, et al. Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity. Thromb Haemost. 2014;112(5):932–940.
-
(2014)
Thromb Haemost.
, vol.112
, Issue.5
, pp. 932-940
-
-
Sommer, J.M.1
Buyue, Y.2
Bardan, S.3
-
45
-
-
85016327498
-
Performance of a recombinant fusion protein linking coagulation factor IX with albumin (rFIX-FP) in the one–stage assay
-
St. Ledger K, Fuessner A, Kalina U, Jacobs I, Voigt C, Bensen-Kennedy D. Performance of a recombinant fusion protein linking coagulation factor IX with albumin (rFIX-FP) in the one–stage assay. Haemophilia. 2016;22:60.
-
(2016)
Haemophilia.
, vol.22
, pp. 60
-
-
St. Ledger, K.1
Fuessner, A.2
Kalina, U.3
Jacobs, I.4
Voigt, C.5
Bensen-Kennedy, D.6
-
46
-
-
84990198558
-
Measuring factor IX activity of nonacog beta pegol with commercially available one-stage clotting and chromogenic assay kits: a two-center study
-
Bowyer AE, Hillarp A, Ezban M, et al. Measuring factor IX activity of nonacog beta pegol with commercially available one-stage clotting and chromogenic assay kits: a two-center study. J Thromb Haemost. 2016;14(7):1428–1435.
-
(2016)
J Thromb Haemost.
, vol.14
, Issue.7
, pp. 1428-1435
-
-
Bowyer, A.E.1
Hillarp, A.2
Ezban, M.3
-
47
-
-
84946497249
-
Factor IX-deficient plasma spiked with N9-GP behaves similarly to N9-GP post-administration clinical samples in N9-GP ELISA and FIX activity assays
-
Sorensen MH, Andersen S, Ezban M. Factor IX-deficient plasma spiked with N9-GP behaves similarly to N9-GP post-administration clinical samples in N9-GP ELISA and FIX activity assays. Haemophilia. 2015;21(6):832–836.
-
(2015)
Haemophilia.
, vol.21
, Issue.6
, pp. 832-836
-
-
Sorensen, M.H.1
Andersen, S.2
Ezban, M.3
-
48
-
-
84990224582
-
Overestimation of N-glycoPEGylated factor IX activity in a one-stage factor IX clotting assay owing to silica-mediated premature conversion to activated factor IX
-
Rosen P, Rosen S, Ezban M, et al. Overestimation of N-glycoPEGylated factor IX activity in a one-stage factor IX clotting assay owing to silica-mediated premature conversion to activated factor IX. J Thromb Haemost. 2016;14(7):1420–1427.
-
(2016)
J Thromb Haemost.
, vol.14
, Issue.7
, pp. 1420-1427
-
-
Rosen, P.1
Rosen, S.2
Ezban, M.3
-
49
-
-
0031828437
-
Discrepancies in potency assessment of recombinant FVIII concentrates
-
Lee CA, Kessler CM, Varon D, et al. Discrepancies in potency assessment of recombinant FVIII concentrates. Haemophilia. 1998;4(4):634–640.
-
(1998)
Haemophilia.
, vol.4
, Issue.4
, pp. 634-640
-
-
Lee, C.A.1
Kessler, C.M.2
Varon, D.3
-
50
-
-
84904723193
-
Evaluation of the activated partial thromboplastin time assay for clinical monitoring of PEGylated recombinant factor VIII (BAY 94–9027) for haemophilia A
-
Gu JM, Ramsey P, Evans V, et al. Evaluation of the activated partial thromboplastin time assay for clinical monitoring of PEGylated recombinant factor VIII (BAY 94–9027) for haemophilia A. Haemophilia. 2014;20(4):593–600.
-
(2014)
Haemophilia.
, vol.20
, Issue.4
, pp. 593-600
-
-
Gu, J.M.1
Ramsey, P.2
Evans, V.3
-
51
-
-
0025311677
-
Potency of high purity factor VIII concentrates
-
Barrowcliffe TW, Watton J, Harman A, et al. Potency of high purity factor VIII concentrates. Lancet. 1990;336(8707):124.
-
(1990)
Lancet.
, vol.336
, Issue.8707
, pp. 124
-
-
Barrowcliffe, T.W.1
Watton, J.2
Harman, A.3
-
52
-
-
0036223409
-
A survey of one-stage and chromogenic potencies in therapeutic factor VIII concentrates
-
Hubbard AR, Weller LJ, Bevan SA. A survey of one-stage and chromogenic potencies in therapeutic factor VIII concentrates. Br J Haematol. 2002;117(1):247–248.
-
(2002)
Br J Haematol.
, vol.117
, Issue.1
, pp. 247-248
-
-
Hubbard, A.R.1
Weller, L.J.2
Bevan, S.A.3
-
53
-
-
33845486921
-
In vitro kinetics of factor VIII activity in patients with mild haemophilia A and a discrepancy between one-stage and two-stage factor VIII assay results
-
Rodgers SE, Duncan EM, Barbulescu DM, et al. In vitro kinetics of factor VIII activity in patients with mild haemophilia A and a discrepancy between one-stage and two-stage factor VIII assay results. Br J Haematol. 2007;136(1):138–145.
-
(2007)
Br J Haematol.
, vol.136
, Issue.1
, pp. 138-145
-
-
Rodgers, S.E.1
Duncan, E.M.2
Barbulescu, D.M.3
-
54
-
-
0023950035
-
Functional and immunological assays of FVIII in 133 haemophiliacs–characterization of a subgroup of patients with mild haemophilia A and discrepancy in 1- and 2-stage assays
-
Parquet-Gernez A, Mazurier C, Goudemand M. Functional and immunological assays of FVIII in 133 haemophiliacs–characterization of a subgroup of patients with mild haemophilia A and discrepancy in 1- and 2-stage assays. Thromb Haemost. 1988;59(2):202–206.
-
(1988)
Thromb Haemost.
, vol.59
, Issue.2
, pp. 202-206
-
-
Parquet-Gernez, A.1
Mazurier, C.2
Goudemand, M.3
-
55
-
-
85051710024
-
Tyr346–>Cys mutation results in factor VIII:C assay discrepancy and a normal bleeding phenotype - is this mild haemophilia A?
-
Lyall H, Hill M, Westby J, et al. Tyr346–>Cys mutation results in factor VIII:C assay discrepancy and a normal bleeding phenotype - is this mild haemophilia A?. Haemophilia. 2007;0(0):071124115610001–071124115610080.
-
(2007)
Haemophilia.
-
-
Lyall, H.1
Hill, M.2
Westby, J.3
-
56
-
-
39549098650
-
Mild hemophilia A with factor VIII assay discrepancy: using thrombin generation assay to assess the bleeding phenotype
-
Trossaert M, Regnault V, Sigaud M, et al. Mild hemophilia A with factor VIII assay discrepancy: using thrombin generation assay to assess the bleeding phenotype. J Thromb Haemost. 2008;6(3):486–493.
-
(2008)
J Thromb Haemost.
, vol.6
, Issue.3
, pp. 486-493
-
-
Trossaert, M.1
Regnault, V.2
Sigaud, M.3
-
57
-
-
84899768541
-
Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays
-
Pavlova A, Delev D, Pezeshkpoor B, et al. Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays. Thromb Haemost. 2014;111(05):851–861.
-
(2014)
Thromb Haemost.
, vol.111
, Issue.5
, pp. 851-861
-
-
Pavlova, A.1
Delev, D.2
Pezeshkpoor, B.3
-
58
-
-
33646839132
-
Factor VIII structure and function
-
Fay PJ. Factor VIII structure and function. Int J Hematol. 2006;83(2):103–108.
-
(2006)
Int J Hematol.
, vol.83
, Issue.2
, pp. 103-108
-
-
Fay, P.J.1
-
59
-
-
0034213347
-
Cn3D: sequence and structure views for Entrez
-
Wang Y, Geer LY, Chappey C, et al. Cn3D: sequence and structure views for Entrez. Trends Biochem Sci. 2000;25(6):300–302.
-
(2000)
Trends Biochem Sci.
, vol.25
, Issue.6
, pp. 300-302
-
-
Wang, Y.1
Geer, L.Y.2
Chappey, C.3
-
60
-
-
0036845615
-
Hemophilia A mutations within the factor VIII A2-A3 subunit interface destabilize factor VIIIa and cause one-stage/two-stage activity discrepancy
-
Hakeos WH, Miao H, Sirachainan N, et al. Hemophilia A mutations within the factor VIII A2-A3 subunit interface destabilize factor VIIIa and cause one-stage/two-stage activity discrepancy. Thromb Haemost. 2002;88(5):781–787.
-
(2002)
Thromb Haemost.
, vol.88
, Issue.5
, pp. 781-787
-
-
Hakeos, W.H.1
Miao, H.2
Sirachainan, N.3
-
61
-
-
85021441807
-
The coagulation laboratory monitoring of Afstyla single-chain FVIII concentrate
-
Bowyer A, Key N, Dalton D, et al. The coagulation laboratory monitoring of Afstyla single-chain FVIII concentrate. Haemophilia. 2017;23(5):e469–e470.
-
(2017)
Haemophilia.
, vol.23
, Issue.5
, pp. e469-e470
-
-
Bowyer, A.1
Key, N.2
Dalton, D.3
-
62
-
-
85044618885
-
Response: The coagulation laboratory monitoring of AFSTYLA single-chain FVIII concentrate
-
Friedman KD, Powell JS, Bensen-Kennedy D. Response: The coagulation laboratory monitoring of AFSTYLA single-chain FVIII concentrate. Haemophilia. 2018;24(3):e129–131.
-
(2018)
Haemophilia.
, vol.24
, Issue.3
, pp. 129-131
-
-
Friedman, K.D.1
Powell, J.S.2
Bensen-Kennedy, D.3
-
63
-
-
84994745295
-
2017 Clinical trials update: Innovations in hemophilia therapy
-
Hartmann J, Croteau SE. 2017 Clinical trials update: Innovations in hemophilia therapy. Am J Hematol. 2016;91(12):1252–1260.
-
(2016)
Am J Hematol.
, vol.91
, Issue.12
, pp. 1252-1260
-
-
Hartmann, J.1
Croteau, S.E.2
-
64
-
-
85051726195
-
Emicizumab subcutaneous dosing every 4 weeks for the management of Hemophilia A: preliminary data from the pharmacokinetic run-in cohort of a multicenter, open-label, phase 3 Study (HAVEN
-
Jimenez-Yuste V, Shima M, Fukutake K, et al. Emicizumab subcutaneous dosing every 4 weeks for the management of Hemophilia A: preliminary data from the pharmacokinetic run-in cohort of a multicenter, open-label, phase 3 Study (HAVEN. Blood. 2017;130:486
-
(2017)
Blood.
, vol.130
, pp. 486
-
-
Jimenez-Yuste, V.1
Shima, M.2
Fukutake, K.3
-
65
-
-
84893537691
-
Anti-factor IXa/X bispecific antibody (ACE910): hemostatic potency against ongoing bleeds in a hemophilia A model and the possibility of routine supplementation
-
Muto A, Yoshihashi K, Takeda M, et al. Anti-factor IXa/X bispecific antibody (ACE910): hemostatic potency against ongoing bleeds in a hemophilia A model and the possibility of routine supplementation. J Thromb Haemost. 2014;12(2):206–213.
-
(2014)
J Thromb Haemost.
, vol.12
, Issue.2
, pp. 206-213
-
-
Muto, A.1
Yoshihashi, K.2
Takeda, M.3
-
66
-
-
84971325206
-
Factor VIII-mimetic function of humanized bispecific antibody in Hemophilia A
-
Shima M, Hanabusa H, Taki M, et al. Factor VIII-mimetic function of humanized bispecific antibody in Hemophilia A. N Engl J Med. 2016;374(21):2044–2053.
-
(2016)
N Engl J Med.
, vol.374
, Issue.21
, pp. 2044-2053
-
-
Shima, M.1
Hanabusa, H.2
Taki, M.3
-
67
-
-
85041670842
-
Long-term safety and efficacy of emicizumab in a phase 1/2 study in patients with hemophilia A with or without inhibitors
-
Shima M, Hanabusa H, Taki M, et al. Long-term safety and efficacy of emicizumab in a phase 1/2 study in patients with hemophilia A with or without inhibitors. Blood Adv. 2017;1(22):1891–1899.
-
(2017)
Blood Adv.
, vol.1
, Issue.22
, pp. 1891-1899
-
-
Shima, M.1
Hanabusa, H.2
Taki, M.3
-
68
-
-
85037622811
-
Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
-
Lenting PJ, Denis CV, Christophe OD. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?. Blood. 2017;130(23):2463–2468.
-
(2017)
Blood.
, vol.130
, Issue.23
, pp. 2463-2468
-
-
Lenting, P.J.1
Denis, C.V.2
Christophe, O.D.3
-
69
-
-
84877607719
-
Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives
-
Young G, Sorensen B, Dargaud Y, et al. Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives. Blood. 2013;121(11):1944–1950.
-
(2013)
Blood.
, vol.121
, Issue.11
, pp. 1944-1950
-
-
Young, G.1
Sorensen, B.2
Dargaud, Y.3
-
71
-
-
84938823121
-
Global/integral assays in hemostasis diagnostics: promises, successes, problems and prospects
-
Panteleev MA, Hemker HC. Global/integral assays in hemostasis diagnostics: promises, successes, problems and prospects. Thrombosis J. 2015;13(1):5.
-
(2015)
Thrombosis J.
, vol.13
, Issue.1
, pp. 5
-
-
Panteleev, M.A.1
Hemker, H.C.2
-
72
-
-
85041654804
-
A microengineered vascularized bleeding model that integrates the principal components of hemostasis
-
Sakurai Y, Hardy ET, Ahn B, et al. A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nat Commun. 2018;9(1):509.
-
(2018)
Nat Commun.
, vol.9
, Issue.1
, pp. 509
-
-
Sakurai, Y.1
Hardy, E.T.2
Ahn, B.3
-
73
-
-
85035107070
-
Nanomechanical clinical coagulation diagnostics and monitoring of therapies
-
Padovani F, Duffy J, Hegner M. Nanomechanical clinical coagulation diagnostics and monitoring of therapies. Nanoscale. 2017;9(45):17939–17947.
-
(2017)
Nanoscale.
, vol.9
, Issue.45
, pp. 17939-17947
-
-
Padovani, F.1
Duffy, J.2
Hegner, M.3
|