A microengineered vascularized bleeding model that integrates the principal components of hemostasis

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Sakurai, Yumiko ^a,b   Hardy, Elaissa T ^a,b   Ahn, Byungwook ^a,b   Tran, Reginald ^a,b   Fay, Meredith E ^a,b   Ciciliano, Jordan C ^c   Mannino, Robert G ^a,b   Myers, David R ^a,b   Qiu, Yongzhi ^a,b   Carden, Marcus A ^b   Baldwin, W Hunter ^b   Meeks, Shannon L ^b   Gilbert, Gary E ^d   Jobe, Shawn M ^e   Lam, Wilbur A ^a,b  

^a Emory University   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Blood Center of Wisconsin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; DIMETICONE; LIPOCORTIN 5; PHOSPHATIDYLSERINE; VON WILLEBRAND FACTOR; LIGAND;

AORTIC ENDOTHELIAL CELL; ARTICLE; BIOMEDICAL ENGINEERING; BLEEDING TIME; BLOOD CLOTTING; BLOOD SAMPLING; CELL SURFACE; CONTROLLED STUDY; HEMOPHILIA A; HEMOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROFLUIDICS; MICROVASCULATURE; SHEAR RATE; SUBENDOTHELIUM; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION; BLEEDING; BLOOD CLOTTING TEST; CELL MEMBRANE; ENDOTHELIUM CELL; MECHANICAL STRESS; METABOLISM; SHEAR STRENGTH; THROMBOCYTE;

BLEEDING TIME; BLOOD COAGULATION; BLOOD COAGULATION TESTS; BLOOD PLATELETS; CELL MEMBRANE; ENDOTHELIAL CELLS; HEMORRHAGE; HEMOSTASIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIGANDS; MICROFLUIDICS; PLATELET ADHESIVENESS; SHEAR STRENGTH; STRESS, MECHANICAL;

EID: 85041654804     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-02990-x     Document Type: Article

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