Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics

Journal of Medicinal Chemistry

Volumn 61, Issue 12, 2018, Pages 5442-5447

  Merk, Daniel ^a   Grisoni, Francesca ^a,b   Friedrich, Lukas ^a   Gelzinyte, Elena ^a   Schneider, Gisbert ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (5,5 DIFLUORO 2,3 DIMETHYL 4,5,6,7 TETRAHYDRO 1H INDOL 1 YL)PHENYL]ACETIC ACID; ANTIBIOTIC AGENT; CONOCARPAN; DEHYDROABIETIC ACID; ISOPIMARIC ACID; NATURAL PRODUCT; RETINOID X RECEPTOR; RETINOID X RECEPTOR BETA; SCLAREOL; UNCLASSIFIED DRUG; VALERENIC ACID; ABIETANE DERIVATIVE; BIOLOGICAL PRODUCT; CARBOXYLIC ACID; INDENE DERIVATIVE; LIGAND; PHENANTHRENE DERIVATIVE; SESQUITERPENE;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG DESIGN; AGONISTS; BIOLOGY; CHEMISTRY; DRUG DEVELOPMENT; HEP-G2 CELL LINE; HUMAN; METABOLISM; PRECLINICAL STUDY; PROCEDURES;

BIOLOGICAL PRODUCTS; CARBOXYLIC ACIDS; COMPUTATIONAL BIOLOGY; DITERPENES, ABIETANE; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HEP G2 CELLS; HUMANS; INDENES; LIGANDS; PHENANTHRENES; RETINOID X RECEPTORS; SESQUITERPENES;

EID: 85049159507     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.8b00494     Document Type: Article

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