Three-dimensional intact-tissue sequencing of single-cell transcriptional states

Science

Volumn 361, Issue 6400, 2018, Pages

  Wang, Xiao ^a   Allen, William E ^a,b   Wright, Matthew A ^a,b   Sylwestrak, Emily L ^a   Samusik, Nikolay ^b   Vesuna, Sam ^a   Evans, Kathryn ^a   Liu, Cindy ^a   Ramakrishnan, Charu ^a   Liu, Jia ^a   Nolan, Garry P ^b   Bava, Felice Alessio ^b,c   Deisseroth, Karl ^a,b  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY   (United States)

^c INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSCRIPTOME;

ANATOMY; BRAIN; CELL; GENE EXPRESSION; GENETIC ANALYSIS; INHIBITION; MOLECULAR ANALYSIS; RNA; RODENT; THREE-DIMENSIONAL MODELING;

ACCURACY; ADULT; AMPLICON; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN SIZE; CELL LABELING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CROSS LINKING; DNA LIBRARY; DNA PROBE; ENDOTHELIUM CELL; GENE AMPLIFICATION; GENE CLUSTER; GENE EXPRESSION; GENE MAPPING; GENETIC TRANSCRIPTION; HIPPOCAMPAL NEURONAL CULTURE; HISTOCHEMISTRY; MEDIAL PREFRONTAL CORTEX; MOUSE; NISSL STAINING; NONHUMAN; OLIGODENDROGLIA; PRELIMBIC CORTEX; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL NOISE RATIO; SINGLE CELL ANALYSIS; SMOOTH MUSCLE CELL; SPATIALLY RESOLVED TRANSCRIPT AMPLICON READOUT MAPPING; STRIATE CORTEX; THREE DIMENSIONAL INTACT TISSUE RNA SEQUENCING; TRANSCRIPTOMICS; ANIMAL; C57BL MOUSE; CHROMOSOMAL MAPPING; CYTOLOGY; FRONTAL LOBE; MALE; METABOLISM; MOLECULAR IMAGING; NERVE CELL; PROCEDURES; SEQUENCE ANALYSIS; SOMATOSENSORY CORTEX; THREE DIMENSIONAL IMAGING; VALIDATION STUDY; VISUAL CORTEX;

ANIMALS; CHROMOSOME MAPPING; FRONTAL LOBE; IMAGING, THREE-DIMENSIONAL; MALE; MICE; MICE, INBRED C57BL; MOLECULAR IMAGING; NEURONS; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS; SOMATOSENSORY CORTEX; TRANSCRIPTION, GENETIC; TRANSCRIPTOME; VISUAL CORTEX;

EID: 85048929494     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aat5691     Document Type: Article

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