The immune checkpoint protein PD-L1 induces and maintains regulatory T cells in glioblastoma

OncoImmunology

Volumn 7, Issue 7, 2018, Pages

  DiDomenico, Joseph ^a   Lamano, Jonathan B ^a   Oyon, Daniel ^a   Li, Yuping ^a   Veliceasa, Dorina ^a   Kaur, Gurvinder ^a   Ampie, Leonel ^b,c   Choy, Winward ^d   Lamano, Jason B ^a   Bloch, Orin ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

glioblastoma; immunosuppression; immunotherapy; nivolumab; pd 1; pd 11; regulatory t cell

Indexed keywords

CELLTRACE; KI 67 ANTIGEN; NIVOLUMAB; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL INFILTRATION; CELL ISOLATION; CELL PROLIFERATION; CLINICAL OUTCOME; CONTROLLED STUDY; DRUG TARGETING; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; LYMPHOCYTE ACTIVATION; MOUSE; MRNA EXPRESSION LEVEL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RNA SEQUENCE; T LYMPHOCYTE ACTIVATION;

EID: 85047959221     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2018.1448329     Document Type: Article

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