Decreased levels of adiponectin in obese patients with gastroesophageal reflux evaluated by videoesophagography: Possible relationship between gastroesophageal reflux and metabolic syndrome

Journal of Gastroenterology and Hepatology (Australia)

Volumn 23, Issue SUPPL. 2, 2008, Pages

  Iwasaki, Eisuke ^a   Suzuki, Hidekazu ^a   Sugino, Yoshinori ^a   Iida, Tsutomu ^a   Nishizawa, Toshihiro ^a   Masaoka, Tatsuhiro ^b   Hosoda, Hiroshi ^c   Kangawa, Kenji ^c   Hibi, Toshifumi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Life Extension Research Institute   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Adiponectin; Gastroesophageal reflux disease; Metabolic syndrome; Videoesophagography

Indexed keywords

ADIPONECTIN; GHRELIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; BODY MASS; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; ESOPHAGOGRAPHY; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; MALE; METABOLIC DISORDER; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUESTIONNAIRE; SCORING SYSTEM; WAIST CIRCUMFERENCE;

EID: 57449100663     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05441.x     Document Type: Conference Paper

References (20)

1. Hampel H, Abraham NS, El-Serag HB. Obesity and the risk for gastroesophageal reflux disease and its complications. Ann. Intern. Med. 2005 143 : 199 211.
2. Jacobson BC, Somers SC, Fuchs CS, Kelly CD, Camargo CA Jr. Body-mass index and symptoms of gastroesophageal reflux in women. N. Engl. J. Med. 2006 354 : 2340 8.
3. El-Serag HB, Ergun GA, Pandolfino J, Fitzgerald S, Tran T, Kramer JR. Obesity increases esophageal acid exposure. Gut 2007 56 : 749 55.
4. Aly YA. Digital radiography in the evaluation of oesophageal motility disorders. Clin. Radiol. 2000 55 : 561 8.
5. Parkman HP, Maurer AH, Carlone DF, Miller DL, Krevsky B, Fisher RS. Optimal evaluation of patients with nonobstructive esophageal dysphagia. Manometry, scintigraphy, or videoesophagography? Dig. Dis. Sci. 1996 41 : 1355 68.
6. Hotta K, Funahashi M, Arita Y et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler. Thromb. Vasc. Biol. 2000 20 : 1595 9.
7. Tschop M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001 50 : 707 9.
8. Mishima I, Adachi K, Arima N et al. Prevalence of endoscopically negative and positive gastroesophageal reflux disease in the Japanese. Scand. J. Gastroenterol. 2005 40 : 1005 9.
9. Haffner SM, Miettinen H, Stern MP. The homeostasis model in the San Antonio Heart Study. Diabetes Care 1997 20 : 1087 92.
10. Masaoka T, Suzuki H, Hosoda H et al. Enhanced plasma ghrelin levels in rats with streptozotocin-induced diabetes. FEBS Lett. 2003 541 : 64 8.
11. Iwasaki E, Suzuki H, Hibi T et al. Enhanced levels of insulin resistance in patients with gastro-esophageal reflux evaluated by flat-panel detector assisted videoesophagography (Abstract). Am. J. Gastroenterol. 2006 101 (Suppl. 9 132.
12. Meining A, Classen M. The role of diet and lifestyle measures in the pathogenesis and treatment of gastroesophageal reflux disease. Am. J. Gastroenterol. 2000 95 : 2692 7.
13. van Herwaarden MA, Katzka DA, Smout AJ, Samsom M, Gideon M, Castell DO. Effect of different recumbent positions on postprandial gastroesophageal reflux in normal subjects. Am. J. Gastroenterol. 2000 95 : 2731 6.
14. Wu JC, Mui LM, Cheung CM, Chan Y, Sung JJ. Obesity is associated with increased transient lower esophageal sphincter relaxation. Gastroenterology 2007 132 : 883 9.
15. Pandolfino E, El-Serag HB, Zhang Q, Shah N, Ghosh SK, Kahrilas PJ. Obesity: a challenge to esophagogastric junction integrity. Gastroenterology 2006 130 : 639 49.
16. Nguyen HN, Domingues GR, Lammert F. Technological insights: combined impedance manometry for esophageal motility testing-current results and further implications. World J. Gastroenterol. 2006 12 : 6266 73.
17. Sugerman HJ, DeMaria EJ, Felton WL 3rd, Nakatsuka M, Sismanis A. Increased intra-abdominal pressure and cardiac filling pressures in obesity-associated pseudotumor cerebri. Neurology 1997 49 : 507 11.
18. Barak N, Ehrenpreis ED, Harrison JR, Sitrin MD. Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations. Obes. Rev. 2002 3 : 9 15.
19. Yamamoto K, Kiyohara T, Murayama Y et al. Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut 2005 54 : 789 96.
20. Nishizawa T, Suzuki H, Hibi T et al. Enhanced plasma ghrelin levels in patients with functional dyspepsia. Aliment. Pharmacol. Ther. 2006 24 (Suppl. 4 104 10.