Polymeric nanoparticles of cholesterol-modified glycol chitosan for doxorubicin delivery: Preparation and in-vitro and in-vivo characterization

Journal of Pharmacy and Pharmacology

Volumn 61, Issue 6, 2009, Pages 713-719

  Yu, Jing Mou ^a,b   Li, Yong Jie ^a   Qiu, Li Yan ^a   Jin, Yi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b YICHUN UNIVERSITY   (China)

Author keywords

Antitumour efficacy; CHGC nanoparticles; Doxorubicin

Indexed keywords

CHITOSAN DERIVATIVE; CHOLESTEROL MODIFIED GLYCOL CHITOSAN; DAUNORUBICIN; DCN 16; DCN 2; DCN 8; DOXORUBICIN; DOXORUBICIN DERIVATIVE; NANOCARRIER; PHOSPHATE BUFFERED SALINE; POLYMER; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; CHITOSAN; CHOLESTEROL; DRUG CARRIER; GLYCOL CHITOSAN; GLYCOL-CHITOSAN; NANOPARTICLE;

ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIALYSIS; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG SOLUBILITY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MALE; MOUSE; NANOENCAPSULATION; NANOFABRICATION; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; PH; RAT; SARCOMA; SINGLE DRUG DOSE; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT OUTCOME; TUMOR MODEL; ANIMAL; CHEMISTRY; DRUG FORMULATION; DRUG SCREENING; INSTITUTE FOR CANCER RESEARCH MOUSE; LIGHT; METABOLISM; NEOPLASM; RADIATION SCATTERING; SOLUBILITY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CHITOSAN; CHOLESTEROL; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; LIGHT; MALE; MICE; MICE, INBRED ICR; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SCATTERING, RADIATION; SOLUBILITY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85047684676     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.61.06.0003     Document Type: Article

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