Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and Na-K-Cl cotransporter NKCC1 isoform mediate the vasorelaxant action of genistein in isolated rat aorta

European Journal of Pharmacology

Volumn 544, Issue 1-3, 2006, Pages 126-131

  Valero, Marta S ^a   Garay, Ricardo P ^a   Gros, Pilar ^a   Alda, José Octavio ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

(Rat); CFTR (cystic fibrosis transmembrane conductance regulator); Genistein; NKCC1; Smooth muscle

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EFENAMIC ACID; GENISTEIN; GLIBENCLAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CHLORIDE TRANSPORT; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; ENDOTHELIUM LESION; IC 50; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; VASODILATATION;

ANIMALS; ANTHRANILIC ACIDS; AORTA; ASPARTIC ACID; CHLORIDES; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GENISTEIN; INHIBITORY CONCENTRATION 50; MALE; NITRATES; RATS; RATS, WISTAR; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS;

EID: 33746653258     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.06.048     Document Type: Article

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