Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Xu, Shuting ^a   Zhu, Xinyuan ^a   Zhang, Chuan ^a   Huang, Wei ^a   Zhou, Yongfeng ^a   Yan, Deyue ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIN E6; CISPLATIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MACROGOL; NANOCOMPOSITE; NANOCONJUGATE; OXYGEN; PHOTOSENSITIZING AGENT; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE 1; PLATINUM COMPLEX; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; UPCONVERSION NANOPARTICLE; NANOPARTICLE; PHYTOCHLORIN; PLATINUM; PORPHYRIN; PRODRUG;

CANCER; CELL; CHLORIN; EFFICIENCY MEASUREMENT; HYPOXIC CONDITIONS; NANOCOMPOSITE; NANOPARTICLE; OXYGEN; PLATINUM; REACTIVE OXYGEN SPECIES; TUMOR; ULTRAVIOLET RADIATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; B16 CELL LINE; BIOCOMPATIBILITY; CANCER INHIBITION; CANCER RESISTANCE; COMBINATION DRUG THERAPY; CONTROLLED STUDY; DECOMPOSITION; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG POTENTIATION; DRUG RELEASE; DRUG RETENTION; EXPERIMENTAL NEOPLASM; FEMALE; HCT 116 CELL LINE; HELA CELL LINE; IN VITRO STUDY; LIGHT ABSORPTION; LIGHT RELATED PHENOMENA; MALE; MDA-MB-231 CELL LINE; MOUSE; NANOPHARMACEUTICS; NANOTOXICOLOGY; NCTC CLONE 929 CELL LINE; NEAR INFRARED LIGHT; NONHUMAN; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; RAT; TUMOR HYPOXIA; TUMOR MICROENVIRONMENT; ULTRAVIOLET RADIATION; ANIMAL; CHEMISTRY; HUMAN; HYPOXIA; METABOLISM; NEOPLASM; NUDE MOUSE; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; FEMALE; HUMANS; HYPOXIA; MALE; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; OXYGEN; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PLATINUM; PORPHYRINS; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 85047651889     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-04318-1     Document Type: Article

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