Gut Microbiota and Host Metabolism: What Relationship

Neuroendocrinology

Volumn 106, Issue 4, 2018, Pages 352-356

  Mithieux, Gilles ^a  

^a INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE   (France)

Author keywords

Dietary intervention; Gut microbiota; Intestinal gluconeogenesis; Intestinal mucosa; Metabolic control; Obesity; Short chain fatty acids; Soluble fibers

Indexed keywords

SHORT CHAIN FATTY ACID;

AKKERMANSIA MUCINIPHILA; ARTICLE; FERMENTATION; GLUCONEOGENESIS; INTESTINE FLORA; INTESTINE MUCOSA; METABOLIC REGULATION; METABOLISM; NONHUMAN; OBESITY; PREVOTELLA; PREVOTELLA COPRI; PRIORITY JOURNAL; VERRUCOMICROBIA; ANIMAL; HUMAN; METABOLIC DISORDER;

ANIMALS; GASTROINTESTINAL MICROBIOME; HUMANS; METABOLIC DISEASES;

EID: 85046890772     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000484526     Document Type: Article

References (29)

1. Turnbaugh PJ, Bäckhed F, Fulton L, Gordon JI: Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 2008;3:213-223.
2. Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 2013;110:9066-9071.
3. De Vadder F, Kovatcheva-Datchary P, Goncalves D, Vinera J, Zitoun C, Duchampt A, et al. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 2014;156:84-96.
4. Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI: An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006;444:1027-1031.
5. David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014;505:559-563.
6. Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013;500:541-546.
7. Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015;528:262-266.
8. Rieder R, Wisniewski PJ, Alderman BL, Campbell SC: Microbes and mental health: a review. Brain Behav Immun DOI: 10.1016/j.bbi.2017.01.016.
9. Levy M, Kolodziejczyk AA, Thaiss CA, Elinav E: Dysbiosis and the immune system. Nat Rev Immunol 2017;17:219-232.
10. Westfall S, Lomis N, Kahouli I, Dia SY, Singh SP, Prakash S: Microbiome, probiotics and neurodegenerative diseases: deciphering the gut brain axis. Cell Mol Life Sci DOI: 10.1007/s00018-017-2550-9.
11. Cotillard A, Kennedy SP, Kong LC, Prifti E, Pons N, Le Chatelier E, et al. Dietary intervention impact on gut microbial gene richness. Nature 2013;500:585-588.
12. Simpson HL, Campbell BJ: Review article: dietary fibre-microbiota interactions. Aliment Pharmacol Ther 2015;42:158-179.
13. Kovatcheva-Datchary P, Nilsson A, Akrami R, Lee YS, De Vadder F, Arora T, et al. Dietary fiber-induced improvement in glucose metabolism is associated with increased abundance of Prevotella. Cell Metab 2015;22:971-982.
14. Mendeloff AI: Dietary fiber and human health. N Engl J Med 1977;297:811-814.
15. Harley IT, Giles DA, Pfluger PT, Burgess SL, Walters S, Hembree J, et al. Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice. Mol Metab 2013;10:171-183.
16. Reijnders D, Goossens GH, Hermes GD, Neis EP, van der Beek CM, Most J, et al. Effects of gut microbiota manipulation by antibiotics on host metabolism in obese humans: a randomized double-blind placebo-controlled trial. Cell Metab 2016;24:63-74.
17. Obata Y, Pachnis V: The effect of microbiota and the immune system on the development and organization of the enteric nervous system. Gastroenterology 2016;151:836-844.
18. Kabouridis PS, Pachnis V: Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system. J Clin Invest 2015;125:956-964.
19. Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G, Hyland NP: Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Front Cell Neurosci 2015;9:392.
20. Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, et al. Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism. Mol Syst Biol 2017;13:921.
21. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in mice. Nat Med 2017;23:107-113.
22. De Vadder F, Kovatcheva-Datchary P, Zitoun C, Duchampt A, Bäckhed F, Mithieux G: Microbiota-produced succinate improves glucose homeostasis via intestinal gluconeogenesis. Cell Metab 2016;24:151-157.
23. Soty M, Gautier-Stein A, Rajas F, Mithieux G: Gut-brain glucose signaling in energy homeostasis. Cell Metab 2017;25:1231-1242.
24. Mazmanian SK, Round JL, Kasper DL: A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008;453:620-625.
25. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 2013;155:1451-1463.
26. Mithieux G: Metabolic effects of portal vein sensing. Diabetes Obes Metab 2014;16:56-60.
27. Reichardt N, Duncan SH, Young P, Belenguer A, McWilliam Leitch C, Scott KP, et al. Phylogenetic distribution of three pathways for propionate production within the human gut microbiota. ISME J 2014;8:1323-1335.
28. Macfarlane GT, Macfarlane S: Bacteria, colonic fermentation and gastrointestinal health. J AOAC Int 2012;95:50-60.
29. Koh A, De Vadder F, Kovatcheva-Datchary P, Bäckhed F: from dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell 2016;165:1332-1345.