Whole-Exome Sequencing Reveals Uncaptured Variation and Distinct Ancestry in the Southern African Population of Botswana

American Journal of Human Genetics

Volumn 102, Issue 5, 2018, Pages 731-743

  Retshabile, Gaone ^a   Mlotshwa, Busisiwe C ^a   Williams, Lesedi ^a   Mwesigwa, Savannah ^b   Mboowa, Gerald ^b   Huang, Zhuoyi ^c   Rustagi, Navin ^c   Swaminathan, Shanker ^c   Katagirya, Eric ^b   Kyobe, Samuel ^b   Wayengera, Misaki ^b   Kisitu, Grace P ^d   Kateete, David P ^b   Wampande, Eddie M ^b   Maplanka, Koketso ^a   Kasvosve, Ishmael ^a   Pettitt, Edward D ^e   Matshaba, Mogomotsi ^c,e   Nsangi, Betty ^d   Marape, Marape ^e   Tsimako Johnstone, Masego ^a   Brown, Chester W ^c,f   Yu, Fuli ^c   Kekitiinwa, Adeodata ^c,d   Joloba, Moses ^b   Mpoloka, Sununguko W ^a   Mardon, Graeme ^c   Anabwani, Gabriel ^c,e   Hanchard, Neil A ^c   more..

^a UNIVERSITY OF BOTSWANA   (Botswana)

^b MAKERERE UNIVERSITY   (Uganda)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d Baylor College of Medicine Children's Foundation   (Uganda)

^e Princess Marina Hospital   (Botswana)

^f UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Africa; AIDS; genetic mapping; genomics; HIV; population genetics

Indexed keywords

ALLELE; ANCESTRY GROUP; ARCHITECTURE; ARTICLE; BOTSWANA; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; ETHNICITY; FOUNDER EFFECT; GENE FREQUENCY; GENE STRUCTURE; GENETIC DATABASE; GENETIC VARIATION; GENOMICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LANGUAGE; MAJOR CLINICAL STUDY; PLESIOMORPHY; POPULATION STRUCTURE; PREDICTION; PRIORITY JOURNAL; SOUTHERN AFRICAN; WHOLE EXOME SEQUENCING; BLACK PERSON; GENE POOL; GENETICS; GEOGRAPHY; HUMAN GENOME; PHYLOGENY; POPULATION GENETICS; PRINCIPAL COMPONENT ANALYSIS;

AFRICAN CONTINENTAL ANCESTRY GROUP; BOTSWANA; COHORT STUDIES; GENE POOL; GENETIC VARIATION; GENETICS, POPULATION; GENOME, HUMAN; GEOGRAPHY; HUMANS; PHYLOGENY; PRINCIPAL COMPONENT ANALYSIS; WHOLE EXOME SEQUENCING;

EID: 85046157124     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2018.03.010     Document Type: Article

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