NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity

EMBO Journal

Volumn 37, Issue 11, 2018, Pages

  Rajgor, Dipen ^a   Sanderson, Thomas M ^a   Amici, Mascia ^a   Collingridge, Graham L ^a,b,c   Hanley, Jonathan G ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF TORONTO   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Argonaute; dendritic spine; MicroRNA; phosphorylation; synaptic plasticity; translation

Indexed keywords

AMPA RECEPTOR; ARGONAUTE 2 PROTEIN; LIM KINASE 1; MICRORNA; MICRORNA 134; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RNA INDUCED SILENCING COMPLEX; RNA INDUCED SILENCING COMPLEX GW182; SERINE; SERINE 387; UNCLASSIFIED DRUG; AGO2 PROTEIN, RAT; ARGONAUTE PROTEIN; LIM KINASE; LIMK1 PROTEIN, HUMAN; MIRN134 MICRORNA, HUMAN; N-METHYL D-ASPARTATE RECEPTOR SUBTYPE 2A;

ARTICLE; CELL MIGRATION; DENDRITIC SPINE; DOWN REGULATION; GENE; GENE ACTIVITY; GENE REPRESSION; GENE SILENCING; HIPPOCAMPUS; HUMAN; LIMK1 GENE; LONG TERM DEPRESSION; MORPHOGENESIS; NERVE CELL PLASTICITY; NERVE CELL STIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; ANIMAL; GENETICS; METABOLISM; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; RAT;

ANIMALS; ARGONAUTE PROTEINS; DENDRITIC SPINES; HIPPOCAMPUS; HUMANS; LIM KINASES; MICRORNAS; NEURONAL PLASTICITY; NEURONS; PHOSPHORYLATION; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 85046099872     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201797943     Document Type: Article

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