Lipid-drug-conjugate (LDC) solid lipid nanoparticles (SLN) for the delivery of nicotine to the oral cavity – Optimization of nicotine loading efficiency

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 128, Issue , 2018, Pages 10-17

  Ding, Yuan ^a   Nielsen, Kent A ^b   Nielsen, Bruno P ^b   Bøje, Niels W ^b   Müller, Rainer H ^a   Pyo, Sung Min ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b Fertin Pharma AS   (Denmark)

Author keywords

encapsulation efficiency; lipid drug conjugate (LDC); nicotine; Solid lipid nanoparticles (SLN)

Indexed keywords

COUNTERION; FATTY ACID; LIPID; LIPID DRUG CONJUGATE; NICOTINE; SOLID LIPID NANOPARTICLE; STEARIC ACID; UNCLASSIFIED DRUG; DRUG CARRIER; NANOPARTICLE; PALMITIC ACID; STEARIC ACID DERIVATIVE; SUNFLOWER OIL;

ARTICLE; DRUG CONJUGATION; HYDROPHILICITY; LIPOPHILICITY; NANOEMULSION; NANOENCAPSULATION; NANOPHARMACEUTICS; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; ZETA POTENTIAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG FORMULATION; MOUTH; PH; PROCEDURES;

DRUG CARRIERS; DRUG COMPOUNDING; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; MOUTH; NANOPARTICLES; NICOTINE; PALMITIC ACID; STEARIC ACIDS; SUNFLOWER OIL;

EID: 85045684820     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2018.03.004     Document Type: Article

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