Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene - Cytotoxicity testing and mouse serum adsorption

Journal of Controlled Release

Volumn 96, Issue 3, 2004, Pages 425-435

  Olbrich, Carsten ^a,b   Gessner, Andrea ^a   Schröder, Werner ^a   Kayser, Oliver ^a   Müller, Rainer H ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

LDC; Lipid drug conjugate nanoparticles; Serum protein adsorption; Trypanosomiasis

Indexed keywords

CELL CULTURE; LIPIDS; NEUROLOGY; OLEIC ACID; PROTEINS; SLEEP RESEARCH; STEARIC ACID; TOXICITY;

CENTRAL NERVOUS SYSTEM; PARASITES; SLEEPING SICKNESS; TSE-TSE FLY;

NANOSTRUCTURED MATERIALS;

APOLIPOPROTEIN A; APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; DIMINAZENE; DIMINAZENE ACETURATE; FATTY ACID; LIPID; NANOPARTICLE; OLEIC ACID; POLYSORBATE 80; STEARIC ACID;

ABSORPTION; ADSORPTION; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOTOXICITY; DRUG COATING; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; HYDROPHILICITY; IN VIVO STUDY; INCUBATION TIME; MOUSE; NONHUMAN; PRIORITY JOURNAL; SAMPLING;

ADSORPTION; ANIMALS; BLOOD PROTEINS; CELL SURVIVAL; DIMINAZENE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EXCIPIENTS; GRANULOCYTES; HUMANS; ISOELECTRIC FOCUSING; LIPIDS; MICE; MICROSPHERES; PARTICLE SIZE; STEARIC ACIDS; SURFACE PROPERTIES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 2142812902     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.02.024     Document Type: Article

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