Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

Nature Microbiology

Volumn 3, Issue 5, 2018, Pages 600-610

  Ercoli, Giuseppe ^a   Fernandes, Vitor E ^a   Chung, Wen Y ^b   Wanford, Joseph J ^a   Thomson, Sarah ^c   Bayliss, Christopher D ^a   Straatman, Kornelis ^a   Crocker, Paul R ^c   Dennison, Ashley ^b   Martinez Pomares, Luisa ^d   Andrew, Peter W ^a   Moxon, E Richard ^e   Oggioni, Marco R ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b LEICESTER GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; MACROLIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD169; UNCLASSIFIED DRUG; BACTERIAL DNA; SIALOADHESIN; SIGLEC1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; MACROPHAGE; MALE; MICROANALYSIS; MOUSE; NONHUMAN; PIG; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SEPTICEMIA; SPLEEN CELL; STREPTOCOCCUS PNEUMONIAE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; COMPLICATION; CYTOLOGY; DISEASE MODEL; DNA REPLICATION; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; SEPSIS; SPLEEN;

ANIMALS; DISEASE MODELS, ANIMAL; DNA REPLICATION; DNA, BACTERIAL; HUMANS; MACROLIDES; MACROPHAGES; MICE; PNEUMOCOCCAL INFECTIONS; SEPSIS; SIALIC ACID BINDING IG-LIKE LECTIN 1; SPLEEN; STREPTOCOCCUS PNEUMONIAE; SWINE;

EID: 85045475301     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/s41564-018-0147-1     Document Type: Article

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