-
1
-
-
84911408707
-
Transmission of methicillinresistant Staphylococcus aureus via deceased donor liver transplantation confirmed by whole genome sequencing
-
Altman, D.R., R. Sebra, J. Hand, O. Attie, G. Deikus, K.W. Carpini, G. Patel, M. Rana, A. Arvelakis, P. Grewal, et al. 2014. Transmission of methicillinresistant Staphylococcus aureus via deceased donor liver transplantation confirmed by whole genome sequencing. Am. J. Transplant. 14:2640-2644. http://dx.doi.org/10.1111/ajt.12897
-
(2014)
Am. J. Transplant
, vol.14
, pp. 2640-2644
-
-
Altman, D.R.1
Sebra, R.2
Hand, J.3
Attie, O.4
Deikus, G.5
Carpini, K.W.6
Patel, G.7
Rana, M.8
Arvelakis, A.9
Grewal, P.10
-
2
-
-
84961216185
-
Intracellular replication of Staphylococcus aureus in mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination
-
Flannagan, R.S., B. Heit, and D.E. Heinrichs. 2016. Intracellular replication of Staphylococcus aureus in mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination. Cell. Microbiol. 18:514-535. http://dx.doi.org/10.1111/cmi.12527
-
(2016)
Cell. Microbiol
, vol.18
, pp. 514-535
-
-
Flannagan, R.S.1
Heit, B.2
Heinrichs, D.E.3
-
3
-
-
84897513431
-
Where does a Staphylococcus aureus vaccine stand?
-
Fowler, V.G. Jr., and R.A. Proctor. 2014. Where does a Staphylococcus aureus vaccine stand? Clin. Microbiol. Infect. 20(Suppl 5):66-75. http://dx.doi.org/10.1111/1469-0691.12570
-
(2014)
Clin. Microbiol. Infect
, vol.20
, pp. 66-75
-
-
Fowler, V.G.1
Proctor, R.A.2
-
4
-
-
0034177562
-
Survival of Staphylococcus aureus inside neutrophils contributes to infection
-
Gresham, H.D., J.H. Lowrance, T.E. Caver, B.S. Wilson, A.L. Cheung, and F.P. Lindberg. 2000. Survival of Staphylococcus aureus inside neutrophils contributes to infection. J. Immunol. 164:3713-3722. http://dx.doi.org/10.4049/jimmunol.164.7.3713
-
(2000)
J. Immunol
, vol.164
, pp. 3713-3722
-
-
Gresham, H.D.1
Lowrance, J.H.2
Caver, T.E.3
Wilson, B.S.4
Cheung, A.L.5
Lindberg, F.P.6
-
5
-
-
84896391432
-
Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenolsoluble modulin a
-
Grosz, M., J. Kolter, K. Paprotka, A.C. Winkler, D. Schäfer, S.S. Chatterjee, T. Geiger, C. Wolz, K. Ohlsen, M. Otto, et al. 2014. Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenolsoluble modulin a. Cell. Microbiol. 16:451-465. http://dx.doi.org/10.1111/cmi.12233
-
(2014)
Cell. Microbiol
, vol.16
, pp. 451-465
-
-
Grosz, M.1
Kolter, J.2
Paprotka, K.3
Winkler, A.C.4
Schäfer, D.5
Chatterjee, S.S.6
Geiger, T.7
Wolz, C.8
Ohlsen, K.9
Otto, M.10
-
6
-
-
33644775720
-
CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens
-
Helmy, K.Y., K.J. Katschke Jr., N.N. Gorgani, N.M. Kljavin, J.M. Elliott, L. Diehl, S.J. Scales, N. Ghilardi, and M. van Lookeren Campagne. 2006. CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell. 124:915-927. http://dx.doi.org/10.1016/j.cell.2005.12.039
-
(2006)
Cell
, vol.124
, pp. 915-927
-
-
Helmy, K.Y.1
Katschke, K.J.2
Gorgani, N.N.3
Kljavin, N.M.4
Elliott, J.M.5
Diehl, L.6
Scales, S.J.7
Ghilardi, N.8
van Lookeren Campagne, M.9
-
7
-
-
0022393185
-
Prophylactic vancomycin versus placebo in arterial prosthetic reconstructions
-
Jensen, L.J., M.T. Aagaard, and S. Schifter. 1985. Prophylactic vancomycin versus placebo in arterial prosthetic reconstructions. Thorac. Cardiovasc. Surg. 33:300-303. http://dx.doi.org/10.1055/s-2007-1014145
-
(1985)
Thorac. Cardiovasc. Surg
, vol.33
, pp. 300-303
-
-
Jensen, L.J.1
Aagaard, M.T.2
Schifter, S.3
-
8
-
-
77957367098
-
Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice
-
Kinoshita, M., T. Uchida, A. Sato, M. Nakashima, H. Nakashima, S. Shono, Y. Habu, H. Miyazaki, S. Hiroi, and S. Seki. 2010. Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice. J. Hepatol. 53:903-910. http://dx.doi.org/10.1016/j.jhep.2010.04.037
-
(2010)
J. Hepatol
, vol.53
, pp. 903-910
-
-
Kinoshita, M.1
Uchida, T.2
Sato, A.3
Nakashima, M.4
Nakashima, H.5
Shono, S.6
Habu, Y.7
Miyazaki, H.8
Hiroi, S.9
Seki, S.10
-
9
-
-
31044456290
-
Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003
-
Klevens, R.M., J.R. Edwards, F.C. Tenover, L.C. McDonald, T. Horan, and R. Gaynes. National Nosocomial Infections Surveillance System. 2006. Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003. Clin. Infect. Dis. 42:389-391. http://dx.doi.org/10.1086/499367
-
(2006)
Clin. Infect. Dis
, vol.42
, pp. 389-391
-
-
Klevens, R.M.1
Edwards, J.R.2
Tenover, F.C.3
McDonald, L.C.4
Horan, T.5
Gaynes, R.6
-
10
-
-
35349019173
-
Invasive methicillin-resistant Staphylococcus aureus infections in the United States
-
Klevens, R.M., M.A. Morrison, J. Nadle, S. Petit, K. Gershman, S. Ray, L.H. Harrison, R. Lynfield, G. Dumyati, J.M. Townes, et al. Active Bacterial Core surveillance (ABCs) MRSA Investigators. 2007. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA. 298:1763-1771. http://dx.doi.org/10.1001/jama.298.15.1763
-
(2007)
JAMA
, vol.298
, pp. 1763-1771
-
-
Klevens, R.M.1
Morrison, M.A.2
Nadle, J.3
Petit, S.4
Gershman, K.5
Ray, S.6
Harrison, L.H.7
Lynfield, R.8
Dumyati, G.9
Townes, J.M.10
-
11
-
-
84925763736
-
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature
-
Kolaczkowska, E., C.N. Jenne, B.G. Surewaard, A. Thanabalasuriar, W.Y. Lee, M.J. Sanz, K. Mowen, G. Opdenakker, and P. Kubes. 2015. Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature. Nat. Commun. 6:6673. http://dx.doi.org/10.1038/ncomms7673
-
(2015)
Nat. Commun
, vol.6
, pp. 6673
-
-
Kolaczkowska, E.1
Jenne, C.N.2
Surewaard, B.G.3
Thanabalasuriar, A.4
Lee, W.Y.5
Sanz, M.J.6
Mowen, K.7
Opdenakker, G.8
Kubes, P.9
-
12
-
-
65349084974
-
Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors
-
Koziel, J., A. Maciag-Gudowska, T. Mikolajczyk, M. Bzowska, D.E. Sturdevant, A.R. Whitney, L.N. Shaw, F.R. DeLeo, and J. Potempa. 2009. Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. PLoS One. 4:e5210. http://dx.doi.org/10.1371/journal.pone.0005210
-
(2009)
PLoS One
, vol.4
-
-
Koziel, J.1
Maciag-Gudowska, A.2
Mikolajczyk, T.3
Bzowska, M.4
Sturdevant, D.E.5
Whitney, A.R.6
Shaw, L.N.7
DeLeo, F.R.8
Potempa, J.9
-
13
-
-
39049169762
-
A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages
-
Kubica, M., K. Guzik, J. Koziel, M. Zarebski, W. Richter, B. Gajkowska, A. Golda, A. Maciag-Gudowska, K. Brix, L. Shaw, et al. 2008. A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS One. 3:e1409. http://dx.doi.org/10.1371/journal.pone.0001409
-
(2008)
PLoS One
, vol.3
-
-
Kubica, M.1
Guzik, K.2
Koziel, J.3
Zarebski, M.4
Richter, W.5
Gajkowska, B.6
Golda, A.7
Maciag-Gudowska, A.8
Brix, K.9
Shaw, L.10
-
14
-
-
79953907324
-
Impact of vancomycin exposure on outcomes in patients with methicillin-resistant Staphylococcus aureus bacteremia: support for consensus guidelines suggested targets
-
Kullar, R., S.L. Davis, D.P. Levine, and M.J. Rybak. 2011. Impact of vancomycin exposure on outcomes in patients with methicillin-resistant Staphylococcus aureus bacteremia: support for consensus guidelines suggested targets. Clin. Infect. Dis. 52:975-981. http://dx.doi.org/10.1093/cid/cir124
-
(2011)
Clin. Infect. Dis
, vol.52
, pp. 975-981
-
-
Kullar, R.1
Davis, S.L.2
Levine, D.P.3
Rybak, M.J.4
-
15
-
-
84947751820
-
Novel antibody-antibiotic conjugate eliminates intracellular S. aureus
-
Lehar, S.M., T. Pillow, M. Xu, L. Staben, K.K. Kajihara, R. Vandlen, L. DePalatis, H. Raab, W.L. Hazenbos, J.H. Morisaki, et al. 2015. Novel antibody-antibiotic conjugate eliminates intracellular S. aureus. Nature. 527:323-328. http://dx.doi.org/10.1038/nature16057
-
(2015)
Nature
, vol.527
, pp. 323-328
-
-
Lehar, S.M.1
Pillow, T.2
Xu, M.3
Staben, L.4
Kajihara, K.K.5
Vandlen, R.6
DePalatis, L.7
Raab, H.8
Hazenbos, W.L.9
Morisaki, J.H.10
-
16
-
-
0032551901
-
Staphylococcus aureus infections
-
Lowy, F.D. 1998. Staphylococcus aureus infections. N. Engl. J. Med. 339:520-532. http://dx.doi.org/10.1056/NEJM199808203390806
-
(1998)
N. Engl. J. Med
, vol.339
, pp. 520-532
-
-
Lowy, F.D.1
-
17
-
-
0036186240
-
Hepatic abscess in patients with chronic granulomatous disease
-
Lublin, M., D.L. Bartlett, D.N. Danforth, H. Kauffman, J.I. Gallin, H.L. Malech, T. Shawker, P. Choyke, D.E. Kleiner, D.J. Schwartzentruber, et al. 2002. Hepatic abscess in patients with chronic granulomatous disease. Ann. Surg. 235:383-391. http://dx.doi.org/10.1097/00000658-200203000-00010
-
(2002)
Ann. Surg
, vol.235
, pp. 383-391
-
-
Lublin, M.1
Bartlett, D.L.2
Danforth, D.N.3
Kauffman, H.4
Gallin, J.I.5
Malech, H.L.6
Shawker, T.7
Choyke, P.8
Kleiner, D.E.9
Schwartzentruber, D.J.10
-
18
-
-
84897005978
-
Multistate pointprevalence survey of health care-associated infections
-
Magill, S.S., J.R. Edwards, W. Bamberg, Z.G. Beldavs, G. Dumyati, M.A. Kainer, R. Lynfield, M. Maloney, L. McAllister-Hollod, J. Nadle, et al. Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team. 2014. Multistate pointprevalence survey of health care-associated infections. N. Engl. J. Med. 370:1198-1208. http://dx.doi.org/10.1056/NEJMoa1306801
-
(2014)
N. Engl. J. Med
, vol.370
, pp. 1198-1208
-
-
Magill, S.S.1
Edwards, J.R.2
Bamberg, W.3
Beldavs, Z.G.4
Dumyati, G.5
Kainer, M.A.6
Lynfield, R.7
Maloney, M.8
McAllister-Hollod, L.9
Nadle, J.10
-
19
-
-
84895730300
-
Clonal expansion during Staphylococcus aureus infection dynamics reveals the effect of antibiotic intervention
-
McVicker, G., T.K. Prajsnar, A. Williams, N.L. Wagner, M. Boots, S.A. Renshaw, and S.J. Foster. 2014. Clonal expansion during Staphylococcus aureus infection dynamics reveals the effect of antibiotic intervention. PLoS Pathog. 10:e1003959. http://dx.doi.org/10.1371/journal.ppat.1003959
-
(2014)
PLoS Pathog
, vol.10
-
-
McVicker, G.1
Prajsnar, T.K.2
Williams, A.3
Wagner, N.L.4
Boots, M.5
Renshaw, S.A.6
Foster, S.J.7
-
20
-
-
66949140382
-
Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America
-
Mermel, L.A., M. Allon, E. Bouza, D.E. Craven, P. Flynn, N.P. O'Grady, I.I. Raad II, B.J. Rijnders, R.J. Sherertz, and D.K. Warren. 2009. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin. Infect. Dis. 49:1-45. http://dx.doi.org/10.1086/599376
-
(2009)
Clin. Infect. Dis
, vol.49
, pp. 1-45
-
-
Mermel, L.A.1
Allon, M.2
Bouza, E.3
Craven, D.E.4
Flynn, P.5
O'Grady, R.6
Raad, I.I.7
Rijnders, B.J.8
Sherertz, R.J.9
Warren, D.K.10
-
21
-
-
77956356704
-
agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils
-
Pang, Y.Y., J. Schwartz, M. Thoendel, L.W. Ackermann, A.R. Horswill, and W.M. Nauseef. 2010. agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils. J. Innate Immun. 2:546-559. http://dx.doi.org/10.1159/000319855
-
(2010)
J. Innate Immun
, vol.2
, pp. 546-559
-
-
Pang, Y.Y.1
Schwartz, J.2
Thoendel, M.3
Ackermann, L.W.4
Horswill, A.R.5
Nauseef, W.M.6
-
22
-
-
78751585051
-
Preparation of liposomal vancomycin and intracellular killing of meticillin-resistant Staphylococcus aureus (MRSA)
-
Pumerantz, A., K. Muppidi, S. Agnihotri, C. Guerra, V. Venketaraman, J. Wang, and G. Betageri. 2011. Preparation of liposomal vancomycin and intracellular killing of meticillin-resistant Staphylococcus aureus (MRSA). Int. J. Antimicrob. Agents. 37:140-144. http://dx.doi.org/10.1016/j.ijantimicag.2010.10.011
-
(2011)
Int. J. Antimicrob. Agents
, vol.37
, pp. 140-144
-
-
Pumerantz, A.1
Muppidi, K.2
Agnihotri, S.3
Guerra, C.4
Venketaraman, V.5
Wang, J.6
Betageri, G.7
-
23
-
-
77954042229
-
Studies on bacteriemia. I. Mechanisms relating to the persistence of bacteriemia in rabbits following the intravenous injection of staphylococci
-
Rogers, D.E. 1956. Studies on bacteriemia. I. Mechanisms relating to the persistence of bacteriemia in rabbits following the intravenous injection of staphylococci. J. Exp. Med. 103:713-742. http://dx.doi.org/10.1084/jem.103.6.713
-
(1956)
J. Exp. Med
, vol.103
, pp. 713-742
-
-
Rogers, D.E.1
-
24
-
-
53849120901
-
Staphylococcus aureus bacteraemia of unknown primary source: where do we stand?
-
Saginur, R., and K.N. Suh. 2008. Staphylococcus aureus bacteraemia of unknown primary source: where do we stand? Int. J. Antimicrob. Agents. 32(Suppl 1):S21-S25. http://dx.doi.org/10.1016/j.ijantimicag.2008.06.008
-
(2008)
Int. J. Antimicrob. Agents
, vol.32
, pp. S21-S25
-
-
Saginur, R.1
Suh, K.N.2
-
25
-
-
84865389647
-
Liposomal encapsulation of vancomycin improves killing of methicillin-resistant Staphylococcus aureus in a murine infection model
-
Sande, L., M. Sanchez, J. Montes, A.J. Wolf, M.A. Morgan, A. Omri, and G.Y. Liu. 2012. Liposomal encapsulation of vancomycin improves killing of methicillin-resistant Staphylococcus aureus in a murine infection model. J. Antimicrob. Chemother. 67:2191-2194. http://dx.doi.org/10.1093/jac/dks212
-
(2012)
J. Antimicrob. Chemother
, vol.67
, pp. 2191-2194
-
-
Sande, L.1
Sanchez, M.2
Montes, J.3
Wolf, A.J.4
Morgan, M.A.5
Omri, A.6
Liu, G.Y.7
-
26
-
-
84881448414
-
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NAD PH oxidase activation
-
Schlam, D., M. Bohdanowicz, A. Chatgilialoglu, B.E. Steinberg, T. Ueyama, G. Du, S. Grinstein, and G.D. Fairn. 2013. Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NAD PH oxidase activation. J. Biol. Chem. 288:23090-23104. http://dx.doi.org/10.1074/jbc.M113.457606
-
(2013)
J. Biol. Chem
, vol.288
, pp. 23090-23104
-
-
Schlam, D.1
Bohdanowicz, M.2
Chatgilialoglu, A.3
Steinberg, B.E.4
Ueyama, T.5
Du, G.6
Grinstein, S.7
Fairn, G.D.8
-
27
-
-
84861209081
-
Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles
-
Surewaard, B.G., R. Nijland, A.N. Spaan, J.A. Kruijtzer, C.J. de Haas, and J.A. van Strijp. 2012. Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles. PLoS Pathog. 8:e1002606. http://dx.doi.org/10.1371/journal.ppat.1002606
-
(2012)
PLoS Pathog
, vol.8
-
-
Surewaard, B.G.1
Nijland, R.2
Spaan, A.N.3
Kruijtzer, J.A.4
de Haas, C.J.5
van Strijp, J.A.6
-
28
-
-
84898789996
-
Macrophage heterogeneity in liver injury and fibrosis
-
Tacke, F., and H.W. Zimmermann. 2014. Macrophage heterogeneity in liver injury and fibrosis. J. Hepatol. 60:1090-1096. http://dx.doi.org/10.1016/j.jhep.2013.12.025
-
(2014)
J. Hepatol
, vol.60
, pp. 1090-1096
-
-
Tacke, F.1
Zimmermann, H.W.2
-
29
-
-
79952033104
-
Clinical management of Staphylococcus aureus bacteraemia
-
Thwaites, G.E., J.D. Edgeworth, E. Gkrania-Klotsas, A. Kirby, R. Tilley, M.E. Török, S. Walker, H.F. Wertheim, P. Wilson, and M.J. Llewelyn. UK Clinical Infection Research Group. 2011. Clinical management of Staphylococcus aureus bacteraemia. Lancet Infect. Dis. 11:208-222. http://dx.doi.org/10.1016/S1473-3099(10)70285-1
-
(2011)
Lancet Infect. Dis
, vol.11
, pp. 208-222
-
-
Thwaites, G.E.1
Edgeworth, J.D.2
Gkrania-Klotsas, E.3
Kirby, A.4
Tilley, R.5
Török, M.E.6
Walker, S.7
Wertheim, H.F.8
Wilson, P.9
Llewelyn, M.J.10
-
30
-
-
55749109709
-
Fc gamma R-stimulated activation of the NAD PH oxidase: phosphoinositidebinding protein p40phox regulates NAD PH oxidase activity after enzyme assembly on the phagosome
-
Tian, W., X.J. Li, N.D. Stull, W. Ming, C.I. Suh, S.A. Bissonnette, M.B. Yaffe, S. Grinstein, S.J. Atkinson, and M.C. Dinauer. 2008. Fc gamma R-stimulated activation of the NAD PH oxidase: phosphoinositidebinding protein p40phox regulates NAD PH oxidase activity after enzyme assembly on the phagosome. Blood. 112:3867-3877. http://dx.doi.org/10.1182/blood-2007-11-126029
-
(2008)
Blood
, vol.112
, pp. 3867-3877
-
-
Tian, W.1
Li, X.J.2
Stull, N.D.3
Ming, W.4
Suh, C.I.5
Bissonnette, S.A.6
Yaffe, M.B.7
Grinstein, S.8
Atkinson, S.J.9
Dinauer, M.C.10
-
31
-
-
84930239306
-
Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management
-
Tong, S.Y., J.S. Davis, E. Eichenberger, T.L. Holland, and V.G. Fowler Jr. 2015. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin. Microbiol. Rev. 28:603-661. http://dx.doi.org/10.1128/CMR.00134-14
-
(2015)
Clin. Microbiol. Rev
, vol.28
, pp. 603-661
-
-
Tong, S.Y.1
Davis, J.S.2
Eichenberger, E.3
Holland, T.L.4
Fowler, V.G.5
-
32
-
-
79952079593
-
Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection
-
Tuchscherr, L., E. Medina, M. Hussain, W. Völker, V. Heitmann, S. Niemann, D. Holzinger, J. Roth, R.A. Proctor, K. Becker, et al. 2011. Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection. EMBO Mol. Med. 3:129-141. http://dx.doi.org/10.1002/emmm.201000115
-
(2011)
EMBO Mol. Med
, vol.3
, pp. 129-141
-
-
Tuchscherr, L.1
Medina, E.2
Hussain, M.3
Völker, W.4
Heitmann, V.5
Niemann, S.6
Holzinger, D.7
Roth, J.8
Proctor, R.A.9
Becker, K.10
-
33
-
-
80053604734
-
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke
-
Wong, C.H., C.N. Jenne, W.Y. Lee, C. Léger, and P. Kubes. 2011. Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science. 334:101-105. http://dx.doi.org/10.1126/science.1210301
-
(2011)
Science
, vol.334
, pp. 101-105
-
-
Wong, C.H.1
Jenne, C.N.2
Lee, W.Y.3
Léger, C.4
Kubes, P.5
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