Malnutrition, inflamation and atherosclerosis (MIA syndrome) in patients with end stage renal disease on maintenance hemodialysis (a single centre experience)

Diabetes and Metabolic Syndrome: Clinical Research and Reviews

Volumn 12, Issue 2, 2018, Pages 91-97

  Allawi, Ali Abdulmajid Dyab ^a  

^a UNIVERSITY OF BAGHDAD   (Iraq)

Author keywords

Chronic kidney disease; Haemodialysis; MIA syndrome

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; CALCIUM; HEMOGLOBIN; LIPID; PARATHYROID HORMONE; PHOSPHATE; BIOLOGICAL MARKER; SERUM ALBUMIN;

ADULT; AGE; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; BLOOD PRESSURE; CALCIUM BLOOD LEVEL; CAROTID ARTERIOGRAPHY; CAROTID ATHEROSCLEROSIS; CLINICAL EVALUATION; CORRELATION COEFFICIENT; CROSS-SECTIONAL STUDY; DESCRIPTIVE RESEARCH; DIABETES MELLITUS; DISEASE ASSOCIATION; DOPPLER ULTRASONOGRAPHY; DYSLIPIDEMIA; END STAGE RENAL DISEASE; EXPERIENCE; FEMALE; GENDER; HEMODIALYSIS; HEMODIALYSIS PATIENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; INDEPENDENT VARIABLE; INFLAMMATION; LIPID BLOOD LEVEL; MAINTENANCE HEMODIALYSIS; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SMOKING HABIT; TREATMENT DURATION; ATHEROSCLEROSIS; BLOOD; CHRONIC KIDNEY FAILURE; METABOLISM; MIDDLE AGED; SYNDROME; TRENDS;

AGED; ATHEROSCLEROSIS; BIOMARKERS; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFLAMMATION; KIDNEY FAILURE, CHRONIC; MALE; MALNUTRITION; MIDDLE AGED; RENAL DIALYSIS; SERUM ALBUMIN; SYNDROME;

EID: 85045291020     PISSN: 18714021     EISSN: 18780334     Source Type: Journal    
DOI: 10.1016/j.dsx.2017.09.003     Document Type: Article

References (104)

1. Ridker, P.M., Hennekens, C.H., Buring, J.E., C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342 (2000), 836–843.
2. Iseki, K., Kawazoe, N., Fukiyama, K., Serum albumin is a strong predictor of death in chronic dialysis patient. Kidney Int 44 (1993), 115–119.
3. Aronow, W.s., Usefulness of serum creatinine as a marker for coronary events in elderly patients with either systemic hypertension or diabetes mellitus. Am J Cardiol 68 (1991), 678–679.
4. Levin, A., Foley, R.N., Cardiovascular disease in chronic renal insufficiency. Am J Kidney Dis 36 (2003), 24–30.
5. Cheung, A.K., Sarnak, M.J., Yan, G., Atherosclerotic cardiovascular disease risks in chronic haemodialysis patients. Kidney Int 58 (2000), 353–362.
6. Sarnak, M.J., Levey, A.S., Cardiovascular disease and chronic renal disease: a new paradigm. Am J Kidney Dis 35 (2000), 117–131.
7. Kalantar-Zadeh, K., Kopple, J.D., Kamranpour, N., HDL-inflammatory index correlates with poor outcome in hemodialysis patients. Kidney Int 72 (2007), 1149–1156.
8. Laws, R.A., Tapsell, L.C., Kelly, J., Nutritional status and its relationship to quality of life in a sample of chronic hemodialysis patients. J Ren Nutr 10 (2000), 139–147.
9. Prichard, S.S., Comorbidities and their impact on outcome in patients with end-stage renal disease. Kidney Int 57 (2000), 100–104.
10. Carrero, J.J., Stenvinkel, P., Persistent inflammation as a catalyst for other risk factors in chronic kidney disease: a hypothesis proposal. Clin J Am Soc Nephrol 4 (2009), 49–55.
11. Grimble, R.F., Nutritional modulation of cytokine biology. Nutrition 14 (1998), 634–640.
12. Stenvinkel, P., Endothelial dysfunction and inflammation—is there a link. Nephrol Dial Transplant 16 (2001), 1968–1971.
13. Nguyen-Khoa, T., Massy, Z.A., De Bandt, J.P., Oxidative stress and haemodialysis: role of inflammation and duration of dialysis treatment. Nephrol Dial Transplant 16 (2001), 335–340.
14. Handelman, G.J., Walter, M.F., Adhikarla, R., et al. Elevated plasma F2-isoprostanes in patients on long-term hemodialysis. Kidney Int 59 (2001), 1960–1966.
15. Joki, N., Hase, H., Ishikawa, H., et al. Coronary artery disease as a definitive risk factor of short-term out come after starting hemodialys in diabetic renal failure patients. Clin Nephrol 55 (2001), 109–114.
16. Joki, N., Hase, H., Ishikawa, H., et al. Coronary artery disease as a definitive risk factor of short-term outcome after starting hemodialysis in diabetic renal failure patients. Clin Nephrol 55 (2001), 109–114.
17. Nishizawa, Y., Shoji, T., Maekawa, K., et al. Intima–media thickness of carotid artery predicts cardiovascular mortality in hemodialysis patients. Am J Kidney Dis 41 (2003), 76–79.
18. Sánchez-Alvarez, J.E., Delgado-Mallén, P., González-Rinne, A., et al. Carotid ultrasound: prevention of heart disease and mortality on haemodialysis. Nefrologia 30 (2010), 427–434.
19. Mancia, G., De Backer, G., Dominiczak, A., et al. 2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC task force on the management of arterial hypertension. J Hypertens 25 (2007), 1751–1762.
20. Benedetto, F.A., Tripepi, G., Mallamaci, F., et al. Rate of atherosclerotic plaque formation predicts cardiovascular events in ESRD. J Am Soc Nephrol 19 (2008), 757–763.
21. Chambless, L.E., Folsom, A.R., Clegg, L.X., et al. Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study. Am J Epidemiol 151 (2000), 478–487.
22. Bots, M., Hofman, A., Jong, P.D., et al. Common carotid intima–media thickness as an indicator of atherosclerosis at other sites of the carotid artery. The Rotterdam Study. Ann Epidemiol 6 (1996), 147–153.
23. Persson, J., Formgren, J., Israelsson, B., et al. Ultrasound determined intima-media thickness and atherosclerosis: direct and indirect validation. Arterioscler Thromb 4 (1994), 261–264.
24. Schwedler, S., Schinzel, R., Vaith, P., et al. Inflammation and advanced glycation end products in uremia: simple coexistence, potentiation or causal relationship. Kidney Int 59 (2001), 32–36.
25. Miyata, T., Ishiguro, N., Yasuda, Y., et al. Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers. Biochem Biophys Res Commun 244 (1998), 45–49.
26. Kato, S., Chmielewski, M., Honda, H., et al. Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol 3 (2008), 1526–1533.
27. Memoli, B., Postiglione, L., Cianciaruso, B., et al. Role of different dialysis membranes in the release of interleukin-6 soluble receptor in uremic patients. Kidney Int 58 (2000), 417–424.
28. Schouten, W.E.M., Grooteman, M.P.C., van Houte, A.-J., et al. Effects of dialyser and dialysate on the acute phase response in clinical bicarbonate dialysis. Nephrol Dial Transplant 15 (2000), 379–384.
29. Panichi, V., Migliori, M., De Pietro, S., et al. Plasma C-reactive protein in haemodialysis patients. A cross-sectional and longitudinal survey. Blood Purif 18 (2000), 30–36.
30. Fellstrom, B.C., Jardine, A.G., Schmieder, R.E., et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 360 (2009), 1395–1407.
31. Zimmermann, J., Herrlinger, S., Pruy, A., et al. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 55 (1999), 648–658.
32. Yeun, J.Y., Levine, R.A., Mantadilok, V., C-reactive protein predicts all-cause and cardiovascular mortality in haemodialysis patients. Am J Kidney Dis 35 (2000), 469–476.
33. Arici, M., Walls, J., End-stage renal disease, atherosclerosis, and cardiovascular mortality: is C-reactive protein the missing link. Kidney Int 59 (2001), 407–414.
34. Don, B., Kaysen, G., Assessment of inflammation and nutrition in patients with end-stage renal disease. J Nephrol 13 (2000), 249–259.
35. Fernandez-Reyes, M., Alvarez-Ude, F., Sanchez, R., Inflammation and malnutrition as predictors of mortality in patients on hemodialysis. J Nephrol 15 (2002), 136–143.
36. Ikizler, T., Poor nutritional status and inflammation. recommended intake and nutrient supplementation in chronic dialysis patients. Semin Dial, 17, 2004, 471.
37. Qureshi, A.R., Alvestrand, A., Divino-Filho, J.C., Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients. J Am Soc Nephrol 13 (2002), 28–36.
38. Beddhu, S., Kaysen, G.A., Yan, G., HEMO Study Group. Association of serum albumin and atherosclerosis in chronic hemodialysis patients. Am J Kidney Dis 40 (2002), 721–727.
39. Cai, H., Harrison, D.G., Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87 (2000), 840–844.
40. Stenvinkel, P., Heimbü rger, O., Paultre, F., Strong associations between malnutrition, inflammation and atherosclerosis in chronic renal failure. Kidney Int 55 (1999), 1899–1911.
41. Bergstrom, J., Lindholm, B., Malnutrition, cardiac disease, and mortality: an integrated point of view. Am J Kidney Dis 32 (1998), 834–841.
42. Kalantar-Zadeh, K., Kopple, J.D., Blocke, G., A malnutrition inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. Am J Kidney Dis 38 (2001), 1251–1263.
43. Stenvinkel, P., Heimbürger, O., Lindholm, B., Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation, and atherosclerosis (MIA syndrome). Nephrol Dial Transplant 15 (2000), 953–960.
44. Kirushnan, B.B., Subba Rao, B., Annigeri, R., Balasubramanian, S., Seshadri, R., Prakash, K.C., Impact of malnutrition, inflammation, and atherosclerosis on the outcome in hemodialysis patients. Indian J Nephrol 27:4 (2017), 277–283.
45. Kalantar-Zadeh, K., Kilpatrick, R.D., Kuwae, N., mortality predictability of serum albumin in the dialysis population: time dependency, longitudinal changes and population-attributable fraction. Nephrol Dial Transplant 20 (2005), 1880–1888.
46. Cano, N.J., Miolane-Debouit, M., Leger, J., Assessment of body protein: energy status in chronic kidney disease. Semin Nephrol 29 (2009), 59–66.
47. Schouten, W.E.M., Grooteman, M.P.C., van Houte, A.-J., Effects of dialyser and dialysate on the acute phase response in clinical bicarbonate dialysis. Nephrol Dial Transplant 15 (2000), 379–384.
48. Schindler, R., Boenisch, O., Fischer, C., Effect of the haemodialysis membrane on the inflammatory reaction in vivo. Clin Nephrol 53 (2000), 452–459.
49. Lagrand, W.K., Niessen, H.W.M., Wolbink, G.-J., C-reactive protein colocalizes with complement in human hearts during acute myocardial infarction. Circulation 95 (1997), 97–103.
50. Stenvinkel, P., Andersson, P., Wang, T., Do ACE-inhibitors suppress tumor necrosis factor-alpha production in advanced chronic renal failure. J Intern Med 246 (1999), 503–507.
51. Witko-Sarsat, V., Friedlander, M., Khoa, T.N., Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure. J Immunol 161 (1998), 2524–2532.
52. Fukuzawa, M., Satoh, J., Sagara, M., Angiotensin-converting enzyme inhibitors suppress production of tumor necrosis factor-alpha in vitro and in vivo. Immunopharmacology 36 (1997), 49–55.
53. Savica, V., Santoro, D., Mazzaglia, G., L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients. J Ren Nutr 15 (2005), 225–230.
54. Ridker, P.M., Danielson, E., Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359 (2008), 2195–2207.
55. Fellstrom, B.C., Jardine, A.G., Schmieder, R.E., Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 360 (2009), 1395–1407.
56. Devaraj, S., Jialal, I., Alpha tocopherol supplementation decreases serum C-reactive protein and monocyte interleukin-6 levels in normal volunteers and type-2 diabetic patients. Free Radical Biol Med 29 (2000), 790–792.
57. Uppritchard, J.E., Sutherland, W.H.F., Mann, J.I., Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care 23 (2000), 733–738.
58. Islam, K.N., O'Byrne, D., Devaraj, S., Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapy. Atherosclerosis 150 (2000), 217–224.
59. Boaz, M., Smetana, S., Weinstein, T., Secondary prevention with antioxidants of cardiovascular disease in end stage renal disease: randomised placebo-controlled trial. Lancet 356 (2000), 1213–1218.
60. How, P., Lau, A., Malnutrition in patients undergoing hemodialysis: is intradialytic parenteral nutrition the answer?. Pharmacotherapy 24 (2004), 1748–1758.
61. National Kidney Foundation - Kidney Disease Outcome Quality Initiative Committee, Adult guidelines. Am J Kidney Dis 35 (2000), 17–104.
62. Pearsonta, Mensahga, Alexanderrw, Markers of inflammation and cardiovascular disease: application to clinical and public health practice. A statement for health care professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107 (2003), 499–511.
63. Touboul, P.J., Hennerici, M.G., Meairs, S., Carotid intima- media thickness and plaque consensus. Cerebrovasc Dis 34 (2012), 290–296.
64. Mancia, G., De Backer, G., Dominiczak, A., 2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC task force on the management of arterial hypertension. J Hypertens 25 (2007), 1751–1762.
65. World Health Organization, Obesity: preventing and managing the global epidemic. Report of a WHO convention, Geneva, 1999., 2000, WHO technical report series 894, Geneva.
66. Kawagishi, T., Nishizawa, Y., Konishi, T., High-resolution B-mode ultrasonography in evaluation of atherosclerosis in uremia. Kidney Int 48 (1995), 820–826.
67. Chobanian, A.V., Bakris, G.L., Black, H.R., The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. The JNC 7 report. JAMA, 289, 2003, 2560.
68. Sarnak, m.j., Cardiovascular complications in chronic kidney disease. Am J Kidney Dis 41 (2003), 11–17.
69. Ishimura, e., Shoji, t., Emoto, m., Renal insufficiency accelerates atherosclerosis in patients with type 2 diabetes mellitus. Am J Kidney Dis 38 (2001), 186–190.
70. Oh, J., Wunsch, R., Turzer, M., Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure. Circulation 106 (2002), 100–105.
71. Yildiz, A., Tepe, S., Oflaz, H., Carotid atherosclerosis is a predictor of coronary calcification in chronic haemodialysis patients. Nephrol Dial Transplant 19 (2004), 885–891.
72. Alatbee, Mohammed Younus Naji, Allawi, Ali Abdulmajid Dyab, Rasheed, Jawad Ibrahim, Relationship of fetuin A and coronary artery calcification in hemodialysis patients. Int J Med Pharm Sci 5:5 (2015), 41–48.
73. Kennedy, R., Case, C., Fathi, R., Does renal failure cause an atherosclerotic milieu in patients with end-stage renal disease?. Am J Med 110 (2001), 198–204.
74. Hojs, R., Carotid intima-media thickness and plaques in hemodialysis patients. Artif Organs 24 (2000), 691–695.
75. Lorenz, M.W., Markus, H.S., Bots, M.L., Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 115 (2007), 459–467.
76. Zhang, L., Zhao, F., Yang, Y., Association between carotid artery intima-media thickness and early-stage CKD in a Chinese population. Am J Kidney Dis 49 (2007), 786–792.
77. Fouque, D., Kalantar-Zadeh, K., Kopple, J., A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 73 (2008), 391–398.
78. Kalantar-Zadeh, K., Recent advances in understanding the malnutrition-inflammation- cachexia syndrome in chronic kidney disease patients. what is next?. Semin Dial 18 (2005), 365–369.
79. Kalantar-Zadeh, K., Ikizler, T.A., Block, G., Malnutrition–inflammation complex syndrome in dialysis patients. Causes and consequence. Am J Kidney Dis 42 (2003), 864–881.
80. Lowrie, E.G., Lew, N.L., Death risk in hemodialysis patients: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis 15 (1990), 458–482.
81. Foley, R.N., Parfrey, P.S., Harnett, J.D., Hypoalbuminemia, cardiac morbidity, and motality in end-stage renal disease. J Am Soc Nephrol 7 (1996), 728–736.
82. Collins, A.J., Li, S., Ma, J.Z., Cardiovascular disease in end-stage renal disease patients. Am J Kidney Dis 38 (2001), 26–29.
83. Stenvinkel, P., The role of inflammation in the anaemia of end stage renal disease. Nephrol Dial Transplant 16 (2001), 36–40.
84. Stenvinkel, P., Inflammation in end-stage renal disease: could it be treated. Nephrol dial therapy 17 (2002), 33–38.
85. Stenvinkel, P., Inflammation in end-stage renal disease: the hidden enemy. Nephrology 11 (2006), 36–41.
86. Avesani, C.M., Carrero, J.J., Axelsson, J., Inflammation and wasting in chronic kidney disease. Kidney Int 104:Suppl (2006), 8–13.
87. Stenvinkel, P., Lindholm, B., Heimbürger, O., Novel approaches in an integrated therapy of inflammatory-associated wasting in end stage renal disease. Semin Dial 17 (2004), 505–515.
88. Heimbürger, O., Qureshi, A.R., Blaner, W.S., Hand-grip muscle strength, lean body mass and plasma proteins as markers of nutritional status in patients with chronic renal failure close to start of dialysis therapy. Am J Kidney Dis 36 (2000), 1213–1225.
89. Kaysen, G.A., Dubin, J.A., Muller, H.G., The acute-phase response varies with time and predicts serum albumin levels in hemodialysis patients. Kidney Int 58 (2000), 346–352.
90. Kaizu, Y., Ohkawa, S., Odamaki, M., Association between inflammatory mediators and muscle mass in long-term hemodialysis patients. Am J Kidney Dis 42 (2003), 295–302.
91. Caimi, G., Carollo, C., Presti, R., Pathophysiological and clinical aspects of malnutrition in chronic renal failure. Nutr Res Rev 18 (2005), 89–97.
92. Arici, M., Walls, J., End-stage renal disease, atherosclerosis, and cardiovascular mortality. Is C-reactive Protein the missing link?. Kidney Int 59 (2001), 407–414.
93. Zoccali, C., Benedetto, F.A., Mallamaci, F., Inflammation is associated with carotid atherosclerosis in dialysis patients. J Hypertens 18 (2000), 1207–1213.
94. Ridker, P.M., Cushman, M., Stampfer, M.J., Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation 97 (1998), 425–428.
95. Pasceri, V., Willerson, J.T., Yeh, E.T., Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 102 (2000), 2165–2168.
96. Bayes, B., Pastor, M.C., Bonal, J., C-reactive protein, lipid peroxidation and mortality in haemodialysis patients. Nephrol Dial Transplant 18 (2003), 106–112.
97. Racki, S., Zaputovic, L., Mavric, Z., C-reactive protein is a strong predictor of mortality in hemodialysis patients. Ren Fail 28 (2006), 427–433.
98. Papagianni, A., Kalovoulos, M., Kirmizis, D., Carotid atherosclerosis is associated with inflammation and endothelial cell adhesion molecules in chronic haemodialysis patients. Nephrol Dial Transplant 18 (2003), 113–119.
99. Leavey, S.F., Strawderman, R.L., Jones, C.A., Simple nutritional indicators as independent predictors of mortality in hemodialysis patients. Am J Kidney Dis 31 (1998), 997–1006.
100. Kato, A., Takita, T., Maruyama, Y., Chlamydial infection and progression of carotid atherosclerosis in patients on regular haemodialysis. Nephrol Dial Transplant 10 (2004), 2539–2546.
101. Sezer, S., Ozdemir, F.N., Arat, Z., Triad of malnutrition, inflammation, and atherosclerosis in hemodialysis patients. Nephron 91 (2002), 456–462.
102. Foley, R.N., Parfrey, P.S., Sarnak, M.J., Clinical epidemiology of cardiovascular disease in chronic renal failure. Am J Kidney Dis 32 (1998), 112–119.
103. Aronow, W.s., Usefulness of serum creatinine as a marker for coronary events in elderly patients with either systemic hypertension or diabetes mellitus. Am J Cardiol 68 (1991), 678–679.
104. Devaraj, S., Jialal, I., Alpha tocopherol supplementation decreases serum C-reactive protein and monocyte interleukin-6 levels in normal volunteers and type 2 diabetic patients. Free Radic Biol Med 29 (2000), 790–792.