메뉴 건너뛰기




Volumn 121, Issue 10, 2017, Pages 1119-1121

CANTOS trial validates the inflammatory pathogenesis of atherosclerosis: Setting the stage for a new chapter in therapeutic targeting

Author keywords

[No Author keywords available]

Indexed keywords

CANAKINUMAB; MONOCLONAL ANTIBODY;

EID: 85045021289     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.311984     Document Type: Article
Times cited : (62)

References (15)
  • 1
    • 85029568219 scopus 로고    scopus 로고
    • Antiinflammatory therapy with canakinumab for atherosclerotic disease
    • Ridker PM, Everett BM, Thuren T, et al; CANTOS Trial Group. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N Engl J Med. 2017;377:1119-1131. doi: 10.1056/NEJMoa1707914.
    • (2017) N Engl J Med. , vol.377 , pp. 1119-1131
    • Ridker, P.M.1    Everett, B.M.2    Thuren, T.3
  • 2
    • 85028364235 scopus 로고    scopus 로고
    • Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: Exploratory results from a randomised, double-blind, placebo-controlled trial
    • [published online ahead of print August 27, 2017]
    • Ridker PM, MacFadyen JG, Thuren T, Everett BM, Libby P, Glynn RJ; CANTOS Trial Group. Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial [published online ahead of print August 27, 2017]. Lancet. http://dx.doi.org/10.1016/S0140-6736(17)32247-X.
    • Lancet
    • Ridker, P.M.1    MacFadyen, J.G.2    Thuren, T.3    Everett, B.M.4    Libby, P.5    Glynn, R.J.6
  • 3
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836-843. doi: 10.1056/NEJM200003233421202.
    • (2000) N Engl J Med. , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 5
    • 84883134602 scopus 로고    scopus 로고
    • Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: Meta-analyses of individual participant data from randomised trials
    • Bhala N, Emberson J, Merhi A, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet. 2013;382:769-779.
    • (2013) Lancet , vol.382 , pp. 769-779
    • Bhala, N.1    Emberson, J.2    Merhi, A.3
  • 6
    • 81255188900 scopus 로고    scopus 로고
    • Atherosclerosis: Current pathogenesis and therapeutic options
    • Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med. 2011;17:1410-1422. doi: 10.1038/nm.2538.
    • (2011) Nat Med. , vol.17 , pp. 1410-1422
    • Weber, C.1    Noels, H.2
  • 7
    • 84870619337 scopus 로고    scopus 로고
    • Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: A phase IIb randomized, placebo-controlled trial
    • Ridker PM, Howard CP, Walter V, Everett B, Libby P, Hensen J, Thuren T; CANTOS Pilot Investigative Group. Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial. Circulation. 2012;126:2739-2748. doi: 10.1161/CIRCULATIONAHA.112.122556.
    • (2012) Circulation , vol.126 , pp. 2739-2748
    • Ridker, P.M.1    Howard, C.P.2    Walter, V.3    Everett, B.4    Libby, P.5    Hensen, J.6    Thuren, T.7
  • 8
    • 74549184092 scopus 로고    scopus 로고
    • The NLRP3 inflammasome: A sensor for metabolic danger?
    • Schroder K, Zhou R, Tschopp J. The NLRP3 inflammasome: a sensor for metabolic danger? Science. 2010;327:296-300. doi: 10.1126/science.1184003.
    • (2010) Science , vol.327 , pp. 296-300
    • Schroder, K.1    Zhou, R.2    Tschopp, J.3
  • 9
    • 85014889586 scopus 로고    scopus 로고
    • Neutrophils as protagonists and targets in chronic inflammation
    • Soehnlein O, Steffens S, Hidalgo A, Weber C. Neutrophils as protagonists and targets in chronic inflammation. Nat Rev Immunol. 2017;17:248-261. doi: 10.1038/nri.2017.10.
    • (2017) Nat Rev Immunol. , vol.17 , pp. 248-261
    • Soehnlein, O.1    Steffens, S.2    Hidalgo, A.3    Weber, C.4
  • 10
    • 85010198872 scopus 로고    scopus 로고
    • Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
    • Fuster JJ, MacLauchlan S, Zuriaga MA, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355:842-847. doi: 10.1126/science.aag1381.
    • (2017) Science , vol.355 , pp. 842-847
    • Fuster, J.J.1    MacLauchlan, S.2    Zuriaga, M.A.3
  • 11
    • 84963632271 scopus 로고    scopus 로고
    • Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
    • Zimmer S, Grebe A, Bakke SS, et al. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016;8:333ra50. doi: 10.1126/scitranslmed.aad6100.
    • (2016) Sci Transl Med. , vol.8 , pp. 333ra50
    • Zimmer, S.1    Grebe, A.2    Bakke, S.S.3
  • 12
    • 85012859983 scopus 로고    scopus 로고
    • Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation
    • Lindsley RC, Saber W, Mar BG, et al. Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation. N Engl J Med. 2017;376:536-547. doi: 10.1056/NEJMoa1611604.
    • (2017) N Engl J Med. , vol.376 , pp. 536-547
    • Lindsley, R.C.1    Saber, W.2    Mar, B.G.3
  • 13
    • 85009785723 scopus 로고    scopus 로고
    • Expression of specific inflammasome gene modules stratifes older individuals into two extreme clinical and immunological states
    • Furman D, Chang J, Lartigue L, et al. Expression of specific inflammasome gene modules stratifes older individuals into two extreme clinical and immunological states. Nat Med. 2017;23:174-184. doi: 10.1038/nm.4267.
    • (2017) Nat Med. , vol.23 , pp. 174-184
    • Furman, D.1    Chang, J.2    Lartigue, L.3
  • 14
    • 85017438342 scopus 로고    scopus 로고
    • Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation
    • von Hundelshausen P, Agten SM, Eckardt V, et al. Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Sci Transl Med. 2017;9:eaah6650.
    • (2017) Sci Transl Med. , vol.9 , pp. eaah6650
    • Von Hundelshausen, P.1    Agten, S.M.2    Eckardt, V.3
  • 15
    • 85019365154 scopus 로고    scopus 로고
    • Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis
    • Duchene J, Novitzky-Basso I, Thiriot A, et al. Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nat Immunol. 2017;18:753-761. doi: 10.1038/ni.3763.
    • (2017) Nat Immunol. , vol.18 , pp. 753-761
    • Duchene, J.1    Novitzky-Basso, I.2    Thiriot, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.