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Volumn 376, Issue 6, 2017, Pages 536-547

Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation

(17)  Lindsley, R C a   Saber, W e   Mar, B G b   Redd, R c   Wang, T e   Haagenson, M D f   Grauman, P V d   Hu, Z H e   Spellman, S R f   Lee, S J e,h   Verneris, M R g   Hsu, K i   Fleischhauer, K j   Cutler, C a   Antin, J H a   Neuberg, D c   Ebert, B L d  


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CHILD; COHORT ANALYSIS; DNMT3A GENE; GATA2 GENE; GENE; GENE MUTATION; GENE SEQUENCE; HUMAN; JAK2 GENE; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; OVERALL SURVIVAL; PIGA GENE; PPM1D GENE; PROGNOSIS; RELAPSE; SBDS GENE; SEQUENCE ANALYSIS; SF3B1 GENE; SRSF2 GENE; TET2 GENE; TP53 GENE; ADOLESCENT; ALLOTRANSPLANTATION; DNA MUTATIONAL ANALYSIS; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MIDDLE AGED; MUTATION; MYELODYSPLASTIC SYNDROMES; SURVIVAL ANALYSIS; TRANSPLANTATION CONDITIONING; TUMOR SUPPRESSOR GENE; YOUNG ADULT;

EID: 85012859983     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1611604     Document Type: Article
Times cited : (583)

References (27)
  • 1
    • 84922131502 scopus 로고    scopus 로고
    • Genetic predisposition syndromes: When should they be considered in the work-up of MDS?
    • Babushok DV, Bessler M. Genetic predisposition syndromes: When should they be considered in the work-up of MDS? Best Pract Res Clin Haematol 2015; 28: 55-68.
    • (2015) Best Pract Res Clin Haematol , vol.28 , pp. 55-68
    • Babushok, D.V.1    Bessler, M.2
  • 2
    • 84974560145 scopus 로고    scopus 로고
    • The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
    • Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 2016; 127: 2391-405.
    • (2016) Blood , vol.127 , pp. 2391-2405
    • Arber, D.A.1    Orazi, A.2    Hasserjian, R.3
  • 3
    • 84906809218 scopus 로고    scopus 로고
    • Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation
    • Bejar R, Stevenson KE, Caughey B, et al. Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation. J Clin Oncol 2014; 32: 2691-8.
    • (2014) J Clin Oncol , vol.32 , pp. 2691-2698
    • Bejar, R.1    Stevenson, K.E.2    Caughey, B.3
  • 4
    • 84888219405 scopus 로고    scopus 로고
    • Clinical and biological implications of driver mutations in myelodysplastic syndromes
    • Papaemmanuil E, Gerstung M, Malcovati L, et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 2013; 122: 3616-27.
    • (2013) Blood , vol.122 , pp. 3616-3627
    • Papaemmanuil, E.1    Gerstung, M.2    Malcovati, L.3
  • 5
    • 84893772765 scopus 로고    scopus 로고
    • Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
    • Haferlach T, Nagata Y, Grossmann V, et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia 2014; 28: 241-7.
    • (2014) Leukemia , vol.28 , pp. 241-247
    • Haferlach, T.1    Nagata, Y.2    Grossmann, V.3
  • 6
    • 84974539642 scopus 로고    scopus 로고
    • Scoring system prognostic of outcome in patients undergoing allogeneic hematopoietic cell transplantation for myelodysplastic syndrome
    • Shaffer BC, Ahn KW, Hu Z-H, et al. Scoring system prognostic of outcome in patients undergoing allogeneic hematopoietic cell transplantation for myelodysplastic syndrome. J Clin Oncol 2016; 34: 1864-71.
    • (2016) J Clin Oncol , vol.34 , pp. 1864-1871
    • Shaffer, B.C.1    Ahn, K.W.2    Hu, Z.-H.3
  • 7
    • 84901701732 scopus 로고    scopus 로고
    • Predictive factors for the outcome of allogeneic transplantation in patients with MDS stratified according to the revised IPSS-R
    • Della Porta MG, Alessandrino EP, Bacigalupo A, et al. Predictive factors for the outcome of allogeneic transplantation in patients with MDS stratified according to the revised IPSS-R. Blood 2014; 123: 2333-42.
    • (2014) Blood , vol.123 , pp. 2333-2342
    • Della Porta, M.G.1    Alessandrino, E.P.2    Bacigalupo, A.3
  • 8
    • 3142580475 scopus 로고    scopus 로고
    • A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: Delayed transplantation for low-risk myelodysplasia is associated with improved outcome
    • Cutler CS, Lee SJ, Greenberg P, et al. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood 2004; 104: 579-85.
    • (2004) Blood , vol.104 , pp. 579-585
    • Cutler, C.S.1    Lee, S.J.2    Greenberg, P.3
  • 9
    • 84992425369 scopus 로고    scopus 로고
    • Clinical effects of driver somatic mutations on the outcomes of patients with myelodysplastic syndromes treated with allogeneic hematopoietic stem-cell transplantation
    • Epub ahead of print
    • Della Porta MG, Galli A, Bacigalupo A, et al. Clinical effects of driver somatic mutations on the outcomes of patients with myelodysplastic syndromes treated with allogeneic hematopoietic stem-cell transplantation. J Clin Oncol 2016 September 6 (Epub ahead of print).
    • (2016) J Clin Oncol
    • Della, P.M.G.1    Galli, A.2    Bacigalupo, A.3
  • 10
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • Brosh R, Rotter V. When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 2009; 9: 701-13.
    • (2009) Nat Rev Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 11
    • 79959794787 scopus 로고    scopus 로고
    • Clinical effect of point mutations in myelodysplastic syndromes
    • Bejar R, Stevenson K, Abdel-Wahab O, et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med 2011; 364: 2496-506.
    • (2011) N Engl J Med , vol.364 , pp. 2496-2506
    • Bejar, R.1    Stevenson, K.2    Abdel-Wahab, O.3
  • 12
    • 84936160001 scopus 로고    scopus 로고
    • Somatic mutations and clonal hematopoiesis in aplastic anemia
    • Yoshizato T, Dumitriu B, Hosokawa K, et al. Somatic mutations and clonal hematopoiesis in aplastic anemia. N Engl J Med 2015; 373: 35-47.
    • (2015) N Engl J Med , vol.373 , pp. 35-47
    • Yoshizato, T.1    Dumitriu, B.2    Hosokawa, K.3
  • 13
    • 0037229094 scopus 로고    scopus 로고
    • Mutations in SBDS are associated with Shwachman-Diamond syndrome
    • Boocock GRB, Morrison JA, Popovic M, et al. Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nat Genet 2003; 33: 97-101.
    • (2003) Nat Genet , vol.33 , pp. 97-101
    • Boocock, G.R.B.1    Morrison, J.A.2    Popovic, M.3
  • 14
    • 80053385569 scopus 로고    scopus 로고
    • Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
    • Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet 2011; 43: 929-31.
    • (2011) Nat Genet , vol.43 , pp. 929-931
    • Ostergaard, P.1    Simpson, M.A.2    Connell, F.C.3
  • 15
    • 84896542431 scopus 로고    scopus 로고
    • Variable clinical presentation of Shwachman- Diamond syndrome: Update from the North American Shwachman-Dia-mond Syndrome Registry
    • Myers KC, Bolyard AA, Otto B, et al. Variable clinical presentation of Shwachman- Diamond syndrome: update from the North American Shwachman-Dia-mond Syndrome Registry. J Pediatr 2014; 164: 866-70.
    • (2014) J Pediatr , vol.164 , pp. 866-870
    • Myers, K.C.1    Bolyard, A.A.2    Otto, B.3
  • 16
    • 84865838762 scopus 로고    scopus 로고
    • Classification of and risk factors for hematologic complications in a French national cohort of 102 patients with Shwachman-Diamond syndrome
    • Donadieu J, Fenneteau O, Beaupain B, et al. Classification of and risk factors for hematologic complications in a French national cohort of 102 patients with Shwachman-Diamond syndrome. Haematologica 2012; 97: 1312-9.
    • (2012) Haematologica , vol.97 , pp. 1312-1319
    • Donadieu, J.1    Fenneteau, O.2    Beaupain, B.3
  • 17
    • 84994273699 scopus 로고    scopus 로고
    • Results of a phase III randomized, multicenter study of allogeneic stem cell transplantation after high versus reduced intensity conditioning in patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML): Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0901
    • LBA-8. abstract
    • Scott BL, Pasquini MC, Logan B, et al. Results of a phase III randomized, multicenter study of allogeneic stem cell transplantation after high versus reduced intensity conditioning in patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML): Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0901. Blood 2015; 126: LBA-8. abstract.
    • (2015) Blood , vol.126
    • Scott, B.L.1    Pasquini, M.C.2    Logan, B.3
  • 18
    • 84925518008 scopus 로고    scopus 로고
    • Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
    • Wong TN, Ramsingh G, Young AL, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature 2015; 518: 552-5.
    • (2015) Nature , vol.518 , pp. 552-555
    • Wong, T.N.1    Ramsingh, G.2    Young, A.L.3
  • 19
    • 84902086132 scopus 로고    scopus 로고
    • Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine
    • Bally C, Ades L, Renneville A, et al. Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine. Leuk Res 2014; 38: 751-5.
    • (2014) Leuk Res , vol.38 , pp. 751-755
    • Bally, C.1    Ades, L.2    Renneville, A.3
  • 20
    • 84961554506 scopus 로고    scopus 로고
    • Acute myeloid leukemia ontogeny is defined by distinct somatic mutations
    • Lindsley RC, Mar BG, Mazzola E, et al. Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. Blood 2015; 125: 1367-76.
    • (2015) Blood , vol.125 , pp. 1367-1376
    • Lindsley, R.C.1    Mar, B.G.2    Mazzola, E.3
  • 21
  • 22
    • 84885657625 scopus 로고    scopus 로고
    • NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes
    • Murphy DM, Bejar R, Stevenson K, et al. NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes. Leukemia 2013; 27: 2077-81.
    • (2013) Leukemia , vol.27 , pp. 2077-2081
    • Murphy, D.M.1    Bejar, R.2    Stevenson, K.3
  • 23
    • 84860286309 scopus 로고    scopus 로고
    • The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation
    • Ali AY, Abedini MR, Tsang BK. The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation. Oncogene 2012; 31: 2175-86.
    • (2012) Oncogene , vol.31 , pp. 2175-2186
    • Ali, A.Y.1    Abedini, M.R.2    Tsang, B.K.3
  • 24
    • 84878548536 scopus 로고    scopus 로고
    • Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint
    • Kleiblova P, Shaltiel IA, Benada J, et al. Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint. J Cell Biol 2013; 201: 511-21.
    • (2013) J Cell Biol , vol.201 , pp. 511-521
    • Kleiblova, P.1    Shaltiel, I.A.2    Benada, J.3
  • 25
    • 85010637627 scopus 로고    scopus 로고
    • Somatic mosaic mutations in PPM1D and TP53 in the blood of women with ovarian carcinoma
    • Swisher EM, Harrell MI, Norquist BM, et al. Somatic mosaic mutations in PPM1D and TP53 in the blood of women with ovarian carcinoma. JAMA Oncol 2016; 2: 370-2.
    • (2016) JAMA Oncol , vol.2 , pp. 370-372
    • Swisher, E.M.1    Harrell, M.I.2    Norquist, B.M.3
  • 26
    • 84930003179 scopus 로고    scopus 로고
    • Age-related mutations associated with clonal hematopoietic expansion and malignancies
    • Xie M, Lu C, Wang J, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med 2014; 20: 1472-8.
    • (2014) Nat Med , vol.20 , pp. 1472-1478
    • Xie, M.1    Lu, C.2    Wang, J.3
  • 27
    • 84920024296 scopus 로고    scopus 로고
    • Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
    • Genovese G, Kahler AK, Handsaker RE, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N Engl J Med 2014; 371: 2477-87.
    • (2014) N Engl J Med , vol.371 , pp. 2477-2487
    • Genovese, G.1    Kahler, A.K.2    Handsaker, R.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.