-
1
-
-
0031729201
-
[2] Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration
-
Benzie IF, Strain J (1999) [2] Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol 299:15–27
-
(1999)
Methods Enzymol
, vol.299
, pp. 15-27
-
-
Benzie, I.F.1
Strain, J.2
-
3
-
-
36749051047
-
Chronic microglial activation and progressive dopaminergic neurotoxicity
-
Block M, Hong J (2007) Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochem Soc Trans 35:1127–1132
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1127-1132
-
-
Block, M.1
Hong, J.2
-
4
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson’s disease
-
Blum D, Torch S, Lambeng N, Nissou M-F, Benabid A-L, Sadoul R, Verna J-M (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson’s disease. Prog Neurobiol 65:135–172
-
(2001)
Prog Neurobiol
, vol.65
, pp. 135-172
-
-
Blum, D.1
Torch, S.2
Lambeng, N.3
Nissou, M.-F.4
Benabid, A.-L.5
Sadoul, R.6
Verna, J.-M.7
-
5
-
-
22244434468
-
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson’s disease in mice
-
Choi DK et al (2005) Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson’s disease in mice. J Neurosci 25:6594–6600
-
(2005)
J Neurosci
, vol.25
, pp. 6594-6600
-
-
Choi, D.K.1
-
6
-
-
0000341879
-
Free radicals, oxidative stress and neurodegeneration
-
Calne DB, (ed), W. B Saunders, Philadelphia
-
Cohen G (1994) Free radicals, oxidative stress and neurodegeneration. In: Calne DB (ed) Neurodegenerative diseases. W. B Saunders, Philadelphia, pp 139–161
-
(1994)
Neurodegenerative diseases
, pp. 139-161
-
-
Cohen, G.1
-
7
-
-
0034079858
-
Oxidative stress, mitochondrial respiration, and Parkinson’s disease
-
Cohen G (2000) Oxidative stress, mitochondrial respiration, and Parkinson’s disease. Ann N Y Acad Sci 899:112–120
-
(2000)
Ann N Y Acad Sci
, vol.899
, pp. 112-120
-
-
Cohen, G.1
-
8
-
-
79960170945
-
Gastrodin inhibits expression of inducible NO synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-stimulated microglia via MAPK pathways
-
Dai J-N et al (2011) Gastrodin inhibits expression of inducible NO synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-stimulated microglia via MAPK pathways. PLoS ONE 6:e21891
-
(2011)
PLoS ONE
, vol.6
-
-
Dai, J.-N.1
-
9
-
-
33745919520
-
Epidemiology of Parkinson’s disease
-
de Lau LM, Breteler M (2006) Epidemiology of Parkinson’s disease. Lancet Neurol 5:525–535
-
(2006)
Lancet Neurol
, vol.5
, pp. 525-535
-
-
de Lau, L.M.1
Breteler, M.2
-
10
-
-
84881427177
-
Parkinson disease: from pathology to molecular disease mechanisms
-
Dexter DT, Jenner P (2013) Parkinson disease: from pathology to molecular disease mechanisms. Free Radic Biol Med 62:132–144. 10.1016/j.freeradbiomed.2013.01.018
-
(2013)
Free Radic Biol Med
, vol.62
, pp. 132-144
-
-
Dexter, D.T.1
Jenner, P.2
-
11
-
-
84899133012
-
Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model
-
Doo A-R et al (2014) Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model. BMC Complement Altern Med 14:107
-
(2014)
BMC Complement Altern Med
, vol.14
, pp. 107
-
-
Doo, A.-R.1
-
12
-
-
3343003470
-
Neuronal expression of myeloperoxidase is increased in Alzheimer’s disease
-
Green PS, Mendez AJ, Jacob JS, Crowley JR, Growdon W, Hyman BT, Heinecke JW (2004) Neuronal expression of myeloperoxidase is increased in Alzheimer’s disease. J Neurochem 90:724–733
-
(2004)
J Neurochem
, vol.90
, pp. 724-733
-
-
Green, P.S.1
Mendez, A.J.2
Jacob, J.S.3
Crowley, J.R.4
Growdon, W.5
Hyman, B.T.6
Heinecke, J.W.7
-
13
-
-
84885215165
-
Pre-treatment with silymarin reduces brain myeloperoxidase activity and inflammatory cytokines in 6-OHDA hemi-parkinsonian rats
-
Haddadi R, Mohajjel Nayebi A, Brooshghalan SE (2013) Pre-treatment with silymarin reduces brain myeloperoxidase activity and inflammatory cytokines in 6-OHDA hemi-parkinsonian rats. Neurosci Lett 555:106–111
-
(2013)
Neurosci Lett
, vol.555
, pp. 106-111
-
-
Haddadi, R.1
Mohajjel Nayebi, A.2
Brooshghalan, S.E.3
-
14
-
-
84899900564
-
Silymarin improved 6-OHDA-induced motor impairment in hemi-parkisonian rats: behavioral and molecular study DARU
-
Haddadi R, Nayebi AM, Farajniya S, Brooshghalan SE, Sharifi H (2014) Silymarin improved 6-OHDA-induced motor impairment in hemi-parkisonian rats: behavioral and molecular study DARU. J Pharm Sci 22:38
-
(2014)
J Pharm Sci
, vol.22
, pp. 38
-
-
Haddadi, R.1
Nayebi, A.M.2
Farajniya, S.3
Brooshghalan, S.E.4
Sharifi, H.5
-
15
-
-
84949685207
-
Short-term treatment with silymarin improved 6-OHDA-induced catalepsy and motor imbalance in hemi-parkisonian rats
-
Haddadi R, Brooshghalan SE, Farajniya S, Nayebi AM, Sharifi H (2015) Short-term treatment with silymarin improved 6-OHDA-induced catalepsy and motor imbalance in hemi-parkisonian rats. Adv Pharm Bull 5:463–469. 10.15171/apb.2015.063
-
(2015)
Adv Pharm Bull
, vol.5
, pp. 463-469
-
-
Haddadi, R.1
Brooshghalan, S.E.2
Farajniya, S.3
Nayebi, A.M.4
Sharifi, H.5
-
16
-
-
0035800589
-
Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
-
He Y, Appel S, Le W (2001) Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res 909:187–193
-
(2001)
Brain Res
, vol.909
, pp. 187-193
-
-
He, Y.1
Appel, S.2
Le, W.3
-
17
-
-
84883180845
-
Role of oxidative stress in Parkinson’s disease
-
Hwang O (2013) Role of oxidative stress in Parkinson’s disease. Exp Neurobiol 22:11–17
-
(2013)
Exp Neurobiol
, vol.22
, pp. 11-17
-
-
Hwang, O.1
-
18
-
-
19444370500
-
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson’s disease in mice
-
Iancu R, Mohapel P, Brundin P, Paul G (2005) Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson’s disease in mice. Behav Brain Res 162:1–10
-
(2005)
Behav Brain Res
, vol.162
, pp. 1-10
-
-
Iancu, R.1
Mohapel, P.2
Brundin, P.3
Paul, G.4
-
20
-
-
84903714825
-
Gastrodin protects against MPP+-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells
-
Jiang G, Hu Y, Liu L, Cai J, Peng C, Li Q (2014) Gastrodin protects against MPP+-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells. Neurochem Int 75:79–88
-
(2014)
Neurochem Int
, vol.75
, pp. 79-88
-
-
Jiang, G.1
Hu, Y.2
Liu, L.3
Cai, J.4
Peng, C.5
Li, Q.6
-
22
-
-
84973121796
-
Effects of WR1065 on 6-hydroxydopamine-induced motor imbalance: possible involvement of oxidative stress and inflammatory cytokines
-
Kheradmand A, Nayebi AM, Jorjani M, Khalifeh S, Haddadi R (2016b) Effects of WR1065 on 6-hydroxydopamine-induced motor imbalance: possible involvement of oxidative stress and inflammatory cytokines. Neurosci Lett 627:7–12. 10.1016/j.neulet.2016.05.040
-
(2016)
Neurosci Lett
, vol.627
, pp. 7-12
-
-
Kheradmand, A.1
Nayebi, A.M.2
Jorjani, M.3
Khalifeh, S.4
Haddadi, R.5
-
23
-
-
0034663061
-
Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia
-
Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, Hong JS (2000) Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20:6309–6316
-
(2000)
J Neurosci
, vol.20
, pp. 6309-6316
-
-
Kim, W.G.1
Mohney, R.P.2
Wilson, B.3
Jeohn, G.H.4
Liu, B.5
Hong, J.S.6
-
24
-
-
84875454372
-
Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson’s disease model
-
Kumar H, Kim I-S, More SV, Kim B-W, Bahk Y-Y, Choi D-K (2013) Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson’s disease model. Evid-Based Complement Altern Med 2013:514095
-
(2013)
Evid-Based Complement Altern Med
, vol.2013
, pp. 514095
-
-
Kumar, H.1
Kim, I.-S.2
More, S.V.3
Kim, B.-W.4
Bahk, Y.-Y.5
Choi, D.-K.6
-
25
-
-
48449094379
-
Microglia and myeloperoxidase: a deadly partnership in neurodegenerative disease
-
Lefkowitz DL, Lefkowitz SS (2008) Microglia and myeloperoxidase: a deadly partnership in neurodegenerative disease. Free Radic Biol Med 45:726–731
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 726-731
-
-
Lefkowitz, D.L.1
Lefkowitz, S.S.2
-
26
-
-
84863260868
-
Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson’s disease model rats
-
PID: 25774170
-
Li C, Chen X, Zhang N, Song Y, Mu Y (2012) Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson’s disease model rats. Neural Regen Res 7:325
-
(2012)
Neural Regen Res
, vol.7
, pp. 325
-
-
Li, C.1
Chen, X.2
Zhang, N.3
Song, Y.4
Mu, Y.5
-
27
-
-
0037215645
-
Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention
-
Liu B, Hong JS (2003) Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 304:1–7
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1-7
-
-
Liu, B.1
Hong, J.S.2
-
28
-
-
85018455052
-
Increased oxidative stress markers in cerebrospinal fluid from healthy subjects with parkinson’s disease-associated LRRK2 gene mutations
-
Loeffler DA, Klaver AC, Coffey MP, Aasly JO, LeWitt PA (2017) Increased oxidative stress markers in cerebrospinal fluid from healthy subjects with parkinson’s disease-associated LRRK2 gene mutations. Front Aging Neurosci 9:89
-
(2017)
Front Aging Neurosci
, vol.9
, pp. 89
-
-
Loeffler, D.A.1
Klaver, A.C.2
Coffey, M.P.3
Aasly, J.O.4
LeWitt, P.A.5
-
29
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson’s and Alzheimer’s disease brains
-
McGeer P, Itagaki S, Boyes B, McGeer E (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson’s and Alzheimer’s disease brains. Neurology 38:1285
-
(1988)
Neurology
, vol.38
, pp. 1285
-
-
McGeer, P.1
Itagaki, S.2
Boyes, B.3
McGeer, E.4
-
30
-
-
0035709008
-
A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite
-
Miranda KM, Espey MG, Wink DA (2001) A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 5:62–71
-
(2001)
Nitric Oxide
, vol.5
, pp. 62-71
-
-
Miranda, K.M.1
Espey, M.G.2
Wink, D.A.3
-
31
-
-
33845211714
-
Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease
-
Mosley RL et al (2006) Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease. Clin Neurosci Res 6:261–281
-
(2006)
Clin Neurosci Res
, vol.6
, pp. 261-281
-
-
Mosley, R.L.1
-
32
-
-
4644232615
-
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
-
Olson JK, Miller SD (2004) Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol 173:3916–3924
-
(2004)
J Immunol
, vol.173
, pp. 3916-3924
-
-
Olson, J.K.1
Miller, S.D.2
-
34
-
-
84939992728
-
Gastrodin alleviates cerebral ischemic damage in mice by improving anti-oxidant and anti-inflammation activities and inhibiting apoptosis pathway
-
Peng Z et al (2015) Gastrodin alleviates cerebral ischemic damage in mice by improving anti-oxidant and anti-inflammation activities and inhibiting apoptosis pathway. Neurochem Res 40:661–673
-
(2015)
Neurochem Res
, vol.40
, pp. 661-673
-
-
Peng, Z.1
-
35
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
Puthalakath H et al (2007) ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129:1337–1349
-
(2007)
Cell
, vol.129
, pp. 1337-1349
-
-
Puthalakath, H.1
-
36
-
-
0033004381
-
Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer’s disease
-
Reynolds WF, Rhees J, Maciejewski D, Paladino T, Sieburg H, Maki RA, Masliah E (1999) Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer’s disease. Exp Neurol 155:31–41
-
(1999)
Exp Neurol
, vol.155
, pp. 31-41
-
-
Reynolds, W.F.1
Rhees, J.2
Maciejewski, D.3
Paladino, T.4
Sieburg, H.5
Maki, R.A.6
Masliah, E.7
-
37
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson’s disease
-
Schapira A, Cooper J, Dexter D, Clark J, Jenner P, Marsden C (1990) Mitochondrial complex I deficiency in Parkinson’s disease. J Neurochem 54:823–827
-
(1990)
J Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.1
Cooper, J.2
Dexter, D.3
Clark, J.4
Jenner, P.5
Marsden, C.6
-
38
-
-
85053570801
-
Effect of chronic administration of buspirone and fluoxetine on inflammatory cytokines in 6-hydroxydopamine-lesioned rats
-
Sharifi H, Nayebi A, Farajnia S, Haddadi R (2014) Effect of chronic administration of buspirone and fluoxetine on inflammatory cytokines in 6-hydroxydopamine-lesioned rats. Drug Res. 64:1–5
-
(2014)
Drug Res.
, vol.64
, pp. 1-5
-
-
Sharifi, H.1
Nayebi, A.2
Farajnia, S.3
Haddadi, R.4
-
39
-
-
84949651815
-
Effect of buspirone, fluoxetine and 8-OH-DPAT on striatal expression of bax, caspase-3 and Bcl-2 proteins in 6-hydroxydopamine-induced hemi-Parkinsonian rats
-
Sharifi H, Nayebi AM, Farajnia S, Haddadi R (2015) Effect of buspirone, fluoxetine and 8-OH-DPAT on striatal expression of bax, caspase-3 and Bcl-2 proteins in 6-hydroxydopamine-induced hemi-Parkinsonian rats. Adv Pharm Bull 5:491
-
(2015)
Adv Pharm Bull
, vol.5
, pp. 491
-
-
Sharifi, H.1
Nayebi, A.M.2
Farajnia, S.3
Haddadi, R.4
-
40
-
-
84889826001
-
Gastrodin promotes the secretion of brain-derived neurotrophic factor in the injured spinal cord
-
PID: 25206433
-
Song C, Fang S, Lv G, Mei X (2013) Gastrodin promotes the secretion of brain-derived neurotrophic factor in the injured spinal cord. Neural Regen Res 8:1383
-
(2013)
Neural Regen Res
, vol.8
, pp. 1383
-
-
Song, C.1
Fang, S.2
Lv, G.3
Mei, X.4
-
41
-
-
0037469952
-
Age-related microglial activation in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
-
Sugama S et al (2003) Age-related microglial activation in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice. Brain Res 964:288–294
-
(2003)
Brain Res
, vol.964
, pp. 288-294
-
-
Sugama, S.1
-
43
-
-
84962217067
-
Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer’s disease
-
Zhang J-S, Zhou S-F, Wang Q, Guo J-N, Liang H-M, Deng J-B, He W-Y (2016) Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer’s disease. Neuroscience 325:1–9
-
(2016)
Neuroscience
, vol.325
, pp. 1-9
-
-
Zhang, J.-S.1
Zhou, S.-F.2
Wang, Q.3
Guo, J.-N.4
Liang, H.-M.5
Deng, J.-B.6
He, W.-Y.7
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