Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids

Cell Chemical Biology

Volumn 25, Issue 4, 2018, Pages 439-446.e5

  Rouhanifard, Sara H ^a   Lopez Aguilar, Aime ^b   Meng, Lu ^c   Moremen, Kelley W ^c   Wu, Peng ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

enteroid; enzymatic glycan engineering; glycosylation; intestinal stem cell; LacNAc; Paneth cells

Indexed keywords

BINDING PROTEIN; DTX2 PROTEIN; FRIZZLED PROTEIN; FRIZZLED PROTEIN FXD1; GLYCAN; GLYCOSYLTRANSFERASE; KAT2A PROTEIN; NOTCH1 RECEPTOR; PROTEIN; UNCLASSIFIED DRUG; WNT1 PROTEIN; AMINOSUGAR; G PROTEIN COUPLED RECEPTOR; LGR5 PROTEIN, MOUSE; N-ACETYLLACTOSAMINE;

ADULT STEM CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL ENGINEERING; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; CRYPT CELL; DOWN REGULATION; FUCOSYLATION; GENE EXPRESSION; GENE FUNCTION; GLYCOCALYX; GLYCOSYLATION; INTESTINE CRYPT; LGR5+ STEM CELL LINE; MOUSE; NONHUMAN; NOTCH SIGNALING; ORGANOID; PANETH CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; HUMAN; METABOLISM; STEM CELL;

AMINO SUGARS; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; GLYCOCALYX; HUMANS; MICE, INBRED C57BL; ORGANOIDS; PANETH CELLS; RECEPTORS, G-PROTEIN-COUPLED; STEM CELLS;

EID: 85044745729     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2018.01.010     Document Type: Article

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