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Volumn 51, Issue , 2018, Pages 154-161

Plasticity and biological diversity of myeloid derived suppressor cells

Author keywords

[No Author keywords available]

Indexed keywords

ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; ARGINASE 1; CELL SURFACE RECEPTOR; CHIMERIC ANTIGEN RECEPTOR; CYTOSTATIC AGENT; ETOMOXIR; FLUOROURACIL; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOSUPPRESSIVE AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROGRAMMED DEATH 1 LIGAND 1; RAPAMYCIN; REACTIVE NITROGEN SPECIES; RETINOIC ACID; SUNITINIB; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR; BIOLOGICAL MARKER;

EID: 85044599039     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2018.03.015     Document Type: Review
Times cited : (51)

References (53)
  • 1
    • 84969919923 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as intruders and targets: clinical implications in cancer therapy
    • Baniyash, M., Myeloid-derived suppressor cells as intruders and targets: clinical implications in cancer therapy. Cancer Immunol Immunother 65 (2016), 857–867.
    • (2016) Cancer Immunol Immunother , vol.65 , pp. 857-867
    • Baniyash, M.1
  • 2
    • 85021784524 scopus 로고    scopus 로고
    • Immune biomarkers for chronic inflammation related complications in non-cancerous and cancerous diseases
    • Meirow, Y., Baniyash, M., Immune biomarkers for chronic inflammation related complications in non-cancerous and cancerous diseases. Cancer Immunol Immunother 66 (2017), 1089–1101.
    • (2017) Cancer Immunol Immunother , vol.66 , pp. 1089-1101
    • Meirow, Y.1    Baniyash, M.2
  • 3
    • 85016111488 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells
    • Gabrilovich, D.I., Myeloid-derived suppressor cells. Cancer Immunol Res 5 (2017), 3–8.
    • (2017) Cancer Immunol Res , vol.5 , pp. 3-8
    • Gabrilovich, D.I.1
  • 5
    • 85017186697 scopus 로고    scopus 로고
    • Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
    • The authors show the M-MDSC and PMN-MDSC mediated regulation of tumor progression, along with MDSC plastic behavior during migration out of the BM, into the tumor and periphery.
    • Ouzounova, M., Lee, E., Piranlioglu, R., El Andaloussi, A., Kolhe, R., Demirci, M.F., Marasco, D., Asm, I., Chadli, A., Hassan, K.A., et al. Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade. Nat Commun, 8, 2017, 14979 The authors show the M-MDSC and PMN-MDSC mediated regulation of tumor progression, along with MDSC plastic behavior during migration out of the BM, into the tumor and periphery.
    • (2017) Nat Commun , vol.8 , pp. 14979
    • Ouzounova, M.1    Lee, E.2    Piranlioglu, R.3    El Andaloussi, A.4    Kolhe, R.5    Demirci, M.F.6    Marasco, D.7    Asm, I.8    Chadli, A.9    Hassan, K.A.10
  • 6
    • 36348991571 scopus 로고    scopus 로고
    • Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma
    • Yamashita, T., Budhu, A., Forgues, M., Wang, X.W., Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Cancer Res 67 (2007), 10831–10839.
    • (2007) Cancer Res , vol.67 , pp. 10831-10839
    • Yamashita, T.1    Budhu, A.2    Forgues, M.3    Wang, X.W.4
  • 7
    • 84958652204 scopus 로고    scopus 로고
    • CD45 phosphatase inhibits STAT3 transcription factor activity in myeloid cells and promotes tumor-associated macrophage differentiation
    • Kumar, V., Cheng, P., Condamine, T., Mony, S., Languino, L.R., McCaffrey, J.C., Hockstein, N., Guarino, M., Masters, G., Penman, E., et al. CD45 phosphatase inhibits STAT3 transcription factor activity in myeloid cells and promotes tumor-associated macrophage differentiation. Immunity 44 (2016), 303–315.
    • (2016) Immunity , vol.44 , pp. 303-315
    • Kumar, V.1    Cheng, P.2    Condamine, T.3    Mony, S.4    Languino, L.R.5    McCaffrey, J.C.6    Hockstein, N.7    Guarino, M.8    Masters, G.9    Penman, E.10
  • 8
    • 84870535425 scopus 로고    scopus 로고
    • Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function
    • Charles, J.F., Hsu, L.Y., Niemi, E.C., Weiss, A., Aliprantis, A.O., Nakamura, M.C., Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J Clin Invest 122 (2012), 4592–4605.
    • (2012) J Clin Invest , vol.122 , pp. 4592-4605
    • Charles, J.F.1    Hsu, L.Y.2    Niemi, E.C.3    Weiss, A.4    Aliprantis, A.O.5    Nakamura, M.C.6
  • 13
    • 85007499773 scopus 로고    scopus 로고
    • The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells
    • Lu, C., Redd, P.S., Lee, J.R., Savage, N., Liu, K., The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells. Oncoimmunology, 5, 2016, e1247135.
    • (2016) Oncoimmunology , vol.5 , pp. e1247135
    • Lu, C.1    Redd, P.S.2    Lee, J.R.3    Savage, N.4    Liu, K.5
  • 14
    • 84941659899 scopus 로고    scopus 로고
    • Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies
    • This study along with Al-Khami et al. shows MDSC metabolic changes upon their infiltration into the tumor, a process determining their cellular fate and function.
    • Hossain, F., Al-Khami, A.A., Wyczechowska, D., Hernandez, C., Zheng, L., Reiss, K., Valle, L.D., Trillo-Tinoco, J., Maj, T., Zou, W., et al. Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies. Cancer Immunol Res 3 (2015), 1236–1247 This study along with Al-Khami et al. shows MDSC metabolic changes upon their infiltration into the tumor, a process determining their cellular fate and function.
    • (2015) Cancer Immunol Res , vol.3 , pp. 1236-1247
    • Hossain, F.1    Al-Khami, A.A.2    Wyczechowska, D.3    Hernandez, C.4    Zheng, L.5    Reiss, K.6    Valle, L.D.7    Trillo-Tinoco, J.8    Maj, T.9    Zou, W.10
  • 16
    • 84971670357 scopus 로고    scopus 로고
    • Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice
    • This paper reveals a new aspect of PMN-MDSC immunosuppressive activity mediated via secreted exosomes, which contain active Arg-1, and thus could be used to attenuate exacerbated immune response.
    • Wang, Y., Tian, J., Tang, X., Rui, K., Tian, X., Ma, J., Ma, B., Xu, H., Lu, L., Wang, S., et al. Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice. Oncotarget 7 (2016), 15356–15368 This paper reveals a new aspect of PMN-MDSC immunosuppressive activity mediated via secreted exosomes, which contain active Arg-1, and thus could be used to attenuate exacerbated immune response.
    • (2016) Oncotarget , vol.7 , pp. 15356-15368
    • Wang, Y.1    Tian, J.2    Tang, X.3    Rui, K.4    Tian, X.5    Ma, J.6    Ma, B.7    Xu, H.8    Lu, L.9    Wang, S.10
  • 19
    • 84938723220 scopus 로고    scopus 로고
    • Myeloid derived suppressor cells — an overview of combat strategies to increase immunotherapy efficacy
    • Draghiciu, O., Lubbers, J., Nijman, H.W., Daemen, T., Myeloid derived suppressor cells — an overview of combat strategies to increase immunotherapy efficacy. Oncoimmunology, 4, 2015, e954829.
    • (2015) Oncoimmunology , vol.4 , pp. e954829
    • Draghiciu, O.1    Lubbers, J.2    Nijman, H.W.3    Daemen, T.4
  • 20
    • 84875511757 scopus 로고    scopus 로고
    • Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation
    • Sade-Feldman, M., Kanterman, J., Ish-Shalom, E., Elnekave, M., Horwitz, E., Baniyash, M., Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. Immunity 38 (2013), 541–554.
    • (2013) Immunity , vol.38 , pp. 541-554
    • Sade-Feldman, M.1    Kanterman, J.2    Ish-Shalom, E.3    Elnekave, M.4    Horwitz, E.5    Baniyash, M.6
  • 21
    • 84994083486 scopus 로고    scopus 로고
    • Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas
    • This study emphasizes the importance of anti-MDSC treatments in combination with immune-based therapies. Combining ATRA and CAR T cell therapies significantly diminished the suppressiveness of MDSCs in the tumor environment and enhanced CAR T cells efficacy.
    • Long, A.H., Highfill, S.L., Cui, Y., Smith, J.P., Walker, A.J., Ramakrishna, S., El-Etriby, R., Galli, S., Tsokos, M.G., Orentas, R.J., et al. Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas. Cancer Immunol Res 4 (2016), 869–880 This study emphasizes the importance of anti-MDSC treatments in combination with immune-based therapies. Combining ATRA and CAR T cell therapies significantly diminished the suppressiveness of MDSCs in the tumor environment and enhanced CAR T cells efficacy.
    • (2016) Cancer Immunol Res , vol.4 , pp. 869-880
    • Long, A.H.1    Highfill, S.L.2    Cui, Y.3    Smith, J.P.4    Walker, A.J.5    Ramakrishna, S.6    El-Etriby, R.7    Galli, S.8    Tsokos, M.G.9    Orentas, R.J.10
  • 22
    • 85018429905 scopus 로고    scopus 로고
    • Frontline science: myeloid-derived suppressor cells (MDSCs) facilitate maternal-fetal tolerance in mice
    • This paper characterizes an evolutionary role for MDSCs as regulators of unwanted immune response during gestation and pregnancy.
    • Ostrand-Rosenberg, S., Sinha, P., Figley, C., Long, R., Park, D., Carter, D., Clements, V.K., Frontline science: myeloid-derived suppressor cells (MDSCs) facilitate maternal-fetal tolerance in mice. J Leukoc Biol, 101, 2016, 10.1189/jlb.1HI1016-306RR This paper characterizes an evolutionary role for MDSCs as regulators of unwanted immune response during gestation and pregnancy.
    • (2016) J Leukoc Biol , vol.101
    • Ostrand-Rosenberg, S.1    Sinha, P.2    Figley, C.3    Long, R.4    Park, D.5    Carter, D.6    Clements, V.K.7
  • 23
    • 84985020938 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells are essential for maintaining feto-maternal immunotolerance via STAT3 signaling in mice
    • Pan, T., Liu, Y., Zhong, L.M., Shi, M.H., Duan, X.B., Wu, K., Yang, Q., Liu, C., Wei, J.Y., Ma, X.R., et al. Myeloid-derived suppressor cells are essential for maintaining feto-maternal immunotolerance via STAT3 signaling in mice. J Leukoc Biol 100 (2016), 499–511.
    • (2016) J Leukoc Biol , vol.100 , pp. 499-511
    • Pan, T.1    Liu, Y.2    Zhong, L.M.3    Shi, M.H.4    Duan, X.B.5    Wu, K.6    Yang, Q.7    Liu, C.8    Wei, J.Y.9    Ma, X.R.10
  • 25
    • 85035151507 scopus 로고    scopus 로고
    • High granulocytic myeloid-derived suppressor cell levels in the peripheral blood predict a better IVF treatment outcome
    • Zhu, M., Huang, X., Yi, S., Sun, H., Zhou, J., High granulocytic myeloid-derived suppressor cell levels in the peripheral blood predict a better IVF treatment outcome. J Matern Neonatal Med, 2017, 10.1080/14767058.2017.1400002.
    • (2017) J Matern Neonatal Med
    • Zhu, M.1    Huang, X.2    Yi, S.3    Sun, H.4    Zhou, J.5
  • 26
    • 0033979660 scopus 로고    scopus 로고
    • Three to six year follow-up of normal donors who received recombinant human granulocyte colony-stimulating factor
    • Cavallaro, A., Lilleby, K., Majolino, I., Storb, R., Appelbaum, F., Rowley, S., Bensinger, W., Three to six year follow-up of normal donors who received recombinant human granulocyte colony-stimulating factor. Bone Marrow Transplant 25 (2000), 85–89.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 85-89
    • Cavallaro, A.1    Lilleby, K.2    Majolino, I.3    Storb, R.4    Appelbaum, F.5    Rowley, S.6    Bensinger, W.7
  • 27
    • 34547182356 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor administration to healthy individuals and persons with chronic neutropenia or cancer: an overview of safety considerations from the Research on Adverse Drug Events and Reports project
    • Tigue, C., Mckoy, J., Evens, A., Trifilio, S., Tallman, M., Bennett, C., Granulocyte-colony stimulating factor administration to healthy individuals and persons with chronic neutropenia or cancer: an overview of safety considerations from the Research on Adverse Drug Events and Reports project. Bone Marrow Transplant 40 (2007), 185–192.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 185-192
    • Tigue, C.1    Mckoy, J.2    Evens, A.3    Trifilio, S.4    Tallman, M.5    Bennett, C.6
  • 29
    • 84992596820 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells induce the expansion of regulatory b cells and ameliorate autoimmunity in the Sanroque mouse model of systemic lupus erythematosus
    • Park, M.-J., Lee, S.-H., Kim, E.-K., Lee, E.-J., Park, S.-H., Kwok, S.-K., Cho, M.-L., Myeloid-derived suppressor cells induce the expansion of regulatory b cells and ameliorate autoimmunity in the Sanroque mouse model of systemic lupus erythematosus. Arthritis Rheumatol 68 (2016), 2717–2727.
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2717-2727
    • Park, M.-J.1    Lee, S.-H.2    Kim, E.-K.3    Lee, E.-J.4    Park, S.-H.5    Kwok, S.-K.6    Cho, M.-L.7
  • 30
    • 84873814690 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in murine retrovirus-induced AIDS inhibit T- and B-cell responses in vitro that are used to define the immunodeficiency
    • Green, K.A., Cook, W.J., Green, W.R., Myeloid-derived suppressor cells in murine retrovirus-induced AIDS inhibit T- and B-cell responses in vitro that are used to define the immunodeficiency. J Virol 87 (2013), 2058–2071.
    • (2013) J Virol , vol.87 , pp. 2058-2071
    • Green, K.A.1    Cook, W.J.2    Green, W.R.3
  • 31
    • 78650474985 scopus 로고    scopus 로고
    • Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13
    • Highfill, S.L., Rodriguez, P.C., Zhou, Q., Goetz, C.A., Koehn, B.H., Veenstra, R., Taylor, P.A., Panoskaltsis-Mortari, A., Serody, J.S., Munn, D.H., et al. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood 116 (2010), 5738–5747.
    • (2010) Blood , vol.116 , pp. 5738-5747
    • Highfill, S.L.1    Rodriguez, P.C.2    Zhou, Q.3    Goetz, C.A.4    Koehn, B.H.5    Veenstra, R.6    Taylor, P.A.7    Panoskaltsis-Mortari, A.8    Serody, J.S.9    Munn, D.H.10
  • 33
    • 84902441141 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells protect mouse models from autoimmune arthritis via controlling inflammatory response
    • Zhang, L., Zhang, Z., Zhang, H., Wu, M., Wang, Y., Myeloid-derived suppressor cells protect mouse models from autoimmune arthritis via controlling inflammatory response. Inflammation 37 (2014), 670–677.
    • (2014) Inflammation , vol.37 , pp. 670-677
    • Zhang, L.1    Zhang, Z.2    Zhang, H.3    Wu, M.4    Wang, Y.5
  • 34
    • 84942431979 scopus 로고    scopus 로고
    • In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity
    • Messmann, J.J., Reisser, T., Leithauser, F., Lutz, M.B., Debatin, K.-M., Strauss, G., In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity. Blood 126 (2015), 1138–1148.
    • (2015) Blood , vol.126 , pp. 1138-1148
    • Messmann, J.J.1    Reisser, T.2    Leithauser, F.3    Lutz, M.B.4    Debatin, K.-M.5    Strauss, G.6
  • 36
    • 84939574415 scopus 로고    scopus 로고
    • Rapamycin prolongs cardiac allograft survival in a mouse model by inducing myeloid-derived suppressor cells
    • Nakamura, T., Nakao, T., Yoshimura, N., Ashihara, E., Rapamycin prolongs cardiac allograft survival in a mouse model by inducing myeloid-derived suppressor cells. Am J Transplant 15 (2015), 2364–2377.
    • (2015) Am J Transplant , vol.15 , pp. 2364-2377
    • Nakamura, T.1    Nakao, T.2    Yoshimura, N.3    Ashihara, E.4
  • 37
    • 77955771348 scopus 로고    scopus 로고
    • GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1-bone marrow progenitor cells into myeloid-derived suppressor cells
    • Morales, J.K., Kmieciak, M., Knutson, K.L., Bear, H.D., Manjili, M.H., GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1-bone marrow progenitor cells into myeloid-derived suppressor cells. Breast Cancer Res Treat 123 (2010), 39–49.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 39-49
    • Morales, J.K.1    Kmieciak, M.2    Knutson, K.L.3    Bear, H.D.4    Manjili, M.H.5
  • 38
    • 84930630721 scopus 로고    scopus 로고
    • Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow
    • Kurkó, J., Vida, A., Ocskó, T., Tryniszewska, B., Rauch, T.A., Glant, T.T., Szekanecz, Z., Mikecz, K., Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow. PLOS ONE, 9, 2014, e111815.
    • (2014) PLOS ONE , vol.9 , pp. e111815
    • Kurkó, J.1    Vida, A.2    Ocskó, T.3    Tryniszewska, B.4    Rauch, T.A.5    Glant, T.T.6    Szekanecz, Z.7    Mikecz, K.8
  • 40
    • 85014021758 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells can be efficiently generated from human hematopoietic progenitors and peripheral blood monocytes
    • Casacuberta-Serra, S., Parés, M., Golbano, A., Coves, E., Espejo, C., Barquinero, J., Myeloid-derived suppressor cells can be efficiently generated from human hematopoietic progenitors and peripheral blood monocytes. Immunol Cell Biol 95 (2017), 538–548.
    • (2017) Immunol Cell Biol , vol.95 , pp. 538-548
    • Casacuberta-Serra, S.1    Parés, M.2    Golbano, A.3    Coves, E.4    Espejo, C.5    Barquinero, J.6
  • 41
    • 85007432965 scopus 로고    scopus 로고
    • Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC)
    • Giallongo, C., Tibullo, D., Parrinello, N.L., Cava, P. La, Rosa, M. Di, Bramanti, V., Raimondo, C. Di, Conticello, C., Chiarenza, A., Palumbo, G.A., et al. Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC). Oncotarget 7 (2016), 85764–85775.
    • (2016) Oncotarget , vol.7 , pp. 85764-85775
    • Giallongo, C.1    Tibullo, D.2    Parrinello, N.L.3    Cava, P.L.4    Rosa, M.D.5    Bramanti, V.6    Raimondo, C.D.7    Conticello, C.8    Chiarenza, A.9    Palumbo, G.A.10
  • 42
    • 84921451497 scopus 로고    scopus 로고
    • A major role for myeloid-derived suppressor cells and a minor role for regulatory T cells in immunosuppression during Staphylococcus aureus infection
    • Tebartz, C., Horst, S.A., Sparwasser, T., Huehn, J., Beineke, A., Peters, G., Medina, E., A major role for myeloid-derived suppressor cells and a minor role for regulatory T cells in immunosuppression during Staphylococcus aureus infection. J Immunol 194 (2015), 1100–1111.
    • (2015) J Immunol , vol.194 , pp. 1100-1111
    • Tebartz, C.1    Horst, S.A.2    Sparwasser, T.3    Huehn, J.4    Beineke, A.5    Peters, G.6    Medina, E.7
  • 43
    • 84928251682 scopus 로고    scopus 로고
    • Granulocytic myeloid derived suppressor cells expansion during active pulmonary tuberculosis is associated with high nitric oxide plasma level
    • El Daker, S., Sacchi, A., Tempestilli, M., Carducci, C., Goletti, D., Vanini, V., Colizzi, V., Lauria, F.N., Martini, F., Martino, A., Granulocytic myeloid derived suppressor cells expansion during active pulmonary tuberculosis is associated with high nitric oxide plasma level. PLOS ONE, 10, 2015, e0123772.
    • (2015) PLOS ONE , vol.10 , pp. e0123772
    • El Daker, S.1    Sacchi, A.2    Tempestilli, M.3    Carducci, C.4    Goletti, D.5    Vanini, V.6    Colizzi, V.7    Lauria, F.N.8    Martini, F.9    Martino, A.10
  • 45
    • 85037685775 scopus 로고    scopus 로고
    • CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation
    • Speigl, L., Burow, H., Bailur, J.K., Janssen, N., Walter, C.-B., Pawelec, G., Shipp, C., CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation. Breast Cancer Res Treat, 2017, 10.1007/s10549-017-4594-9.
    • (2017) Breast Cancer Res Treat
    • Speigl, L.1    Burow, H.2    Bailur, J.K.3    Janssen, N.4    Walter, C.-B.5    Pawelec, G.6    Shipp, C.7
  • 46
  • 49
    • 84951310664 scopus 로고    scopus 로고
    • Aberrant frequency of IL-10-producing B cells and its association with Treg and MDSC cells in non small cell lung carcinoma patients
    • Liu, J., Wang, H., Yu, Q., Zheng, S., Jiang, Y., Liu, Y., Yuan, G., Qiu, L., Aberrant frequency of IL-10-producing B cells and its association with Treg and MDSC cells in non small cell lung carcinoma patients. Hum Immunol 77 (2016), 84–89.
    • (2016) Hum Immunol , vol.77 , pp. 84-89
    • Liu, J.1    Wang, H.2    Yu, Q.3    Zheng, S.4    Jiang, Y.5    Liu, Y.6    Yuan, G.7    Qiu, L.8
  • 51
    • 84942109786 scopus 로고    scopus 로고
    • Polymorphonuclear neutrophils and granulocytic myeloid-derived suppressor cells inhibit natural killer cell activity toward Aspergillus fumigatus
    • Mueller-Leisse, J., Brueggemann, S., Bouzani, M., Schmitt, A.-L., Einsele, H., Loeffler, J., Polymorphonuclear neutrophils and granulocytic myeloid-derived suppressor cells inhibit natural killer cell activity toward Aspergillus fumigatus. Med Mycol 53 (2015), 622–629.
    • (2015) Med Mycol , vol.53 , pp. 622-629
    • Mueller-Leisse, J.1    Brueggemann, S.2    Bouzani, M.3    Schmitt, A.-L.4    Einsele, H.5    Loeffler, J.6
  • 53
    • 84872554724 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer
    • Sawant, A., Deshane, J., Jules, J., Lee, C.M., Harris, B.A., Feng, X., Ponnazhagan, S., Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer. Cancer Res 73 (2013), 672–682.
    • (2013) Cancer Res , vol.73 , pp. 672-682
    • Sawant, A.1    Deshane, J.2    Jules, J.3    Lee, C.M.4    Harris, B.A.5    Feng, X.6    Ponnazhagan, S.7


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