High granulocytic myeloid-derived suppressor cell levels in the peripheral blood predict a better IVF treatment outcome

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 32, Issue 7, 2019, Pages 1092-1097

  Zhu, Mengchen ^a   Huang, Xiaomin ^a   Yi, Shanling ^a   Sun, Haixiang ^a   Zhou, Jianjun ^a  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

Author keywords

granulocytic myeloid derived suppressor cells; in vitro fertilization; Myeloid derived suppressor cells; pregnancy

Indexed keywords

ADULT; ARTICLE; BLOOD; CONTROLLED STUDY; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; IN VITRO FERTILIZATION; MONOCYTE; MYELOID-DERIVED SUPPRESSOR CELL; OBSERVATIONAL STUDY; PREDICTION; PREGNANCY RATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; PREGNANCY; RECEIVER OPERATING CHARACTERISTIC;

ADULT; FEMALE; FERTILIZATION IN VITRO; HUMANS; MYELOID-DERIVED SUPPRESSOR CELLS; PREGNANCY; PREGNANCY RATE; PROSPECTIVE STUDIES; ROC CURVE;

EID: 85035151507     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.1080/14767058.2017.1400002     Document Type: Article

References (23)

1. Noronha LE, Antczak DF., Maternal immune responses to trophoblast: the contribution of the horse to pregnancy immunology. Am J Reprod Immunol. 2010;64(4):231–244
2. Guerin LR, Prins JR, Robertson SA., Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod Update. 2009;15(5):517–535
3. von Rango U., Fetal tolerance in human pregnancy–a crucial balance between acceptance and limitation of trophoblast invasion. Immunol Lett. 2008;115(1):21–32
4. Zhou J, Wang Z, Zhao X, et al. An increase of Treg cells in the peripheral blood is associated with a better in vitro fertilization treatment outcome. Am J Reprod Immunol. 2012;68(2):100–106
5. Rieber N, Gille C, Köstlin N, et al. Neutrophilic myeloid-derived suppressor cells in cord blood modulate innate and adaptive immune responses. Clin Exp Immunol. 2013;174(1):45–52
6. Serafini P., Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly. Immunol Res. 2013;57(1–3):172–184
7. Condamine T, Ramachandran I, Youn JI, et al. Regulation of tumor metastasis by myeloid-derived suppressor cells. Annu Rev Med. 2015;66:97–110
8. Kusmartsev S, Su Z, Heiser A, et al. Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res. 2008;14(24):8270–8278
9. Liu CY, Wang YM, Wang CL, et al. Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14–/CD15+/CD33+, myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer. J Cancer Res Clin Oncol. 2010;136(1):35–45
10. Suzuki E, Kapoor V, Jassar AS, et al. Gemcitabine selectively eliminates splenic Gr-1+/CD11b + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res. 2005;11(18):6713–6721
11. Wallace AE, Fraser R, Cartwright JE., Extravillous trophoblast and decidual natural killer cells: a remodelling partnership. Hum Reprod Update. 2012;18(4):458–471
12. Sinha P, Clements VK, Bunt SK, et al. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol. 2007;179(2):977–983
13. Kang X, Zhang X, Liu Z, et al. Granulocytic myeloid-derived suppressor cells maintain feto-maternal tolerance by inducing Foxp3 expression in CD4+ CD25− T cells by activation of the TGF-β/β-catenin pathway. Mol Hum Reprod. 2016;22(7):499–511
14. Netherby CS, Abrams SI., Mechanisms overseeing myeloid-derived suppressor cell production in neoplastic disease. Cancer Immunol Immunother. 2017;66(8):989–996
15. Gabrilovich DI, Nagaraj S., Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9(3):162–174
16. Nair RR, Sinha P, Khanna A, et al. Reduced myeloid-derived suppressor cells in the blood and endometrium is associated with early miscarriage. Am J Reprod Immunol. 2015;73(6):479–486
17. Youn JI, Nagaraj S, Collazo M, et al. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol. 2008;181(8):5791–5802
18. Köstlin N, Kugel H, Spring B, et al. Granulocytic myeloid derived suppressor cells expand in cord blood and human pregnancy and modulate T cell responses. Eur J Immunol. 2014;44(9):2582–2591
19. Köstlin N, Hofstädter K, Ostermeir AL, et al. Granulocytic myeloid-derived suppressor cells accumulate in human placenta and polarize toward a Th2 phenotype. J Immunol. 2016;196(3):1132–1145
20. Li W, Zhang X, Chen Y, et al. G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers. Protein Cell. 2016;7(2):130–140
21. Lee D, Jo JD, Kim SK, et al. The efficacy of intrauterine instillation of granulocyte colony-stimulating factor in infertile women with a thin endometrium: a pilot study. Clin Exp Reprod Med. 2016;43(4):240–246
22. Eftekhar M, Miraj S, Farid Mojtahedi MF, et al. Efficacy of intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: a randomized control trial. Int J Reprod Biomed (Yazd). 2016;14(11):687–690
23. Li J, Mo S, Chen Y., The effect of G-CSF on infertile women undergoing IVF treatment: a meta-analysis. Syst Biol Reprod Med. 2017;63(4):239–247