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Volumn 4, Issue 1, 2016, Pages

Innate lymphoid cells in tumor immunity

Author keywords

Cancer; Cancer immunotherapy; ILC1s; ILC2s; ILC3s; Innate lymphoid cells (ILCs); Lymphoid tissue inducer (LTi) cells

Indexed keywords


EID: 85044501759     PISSN: None     EISSN: 22279059     Source Type: Journal    
DOI: 10.3390/biomedicines4010007     Document Type: Review
Times cited : (28)

References (116)
  • 4
    • 84876780238 scopus 로고    scopus 로고
    • Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12-and IL-15-responsive IFN-producing cells
    • Fuchs, A.; Vermi, W.; Lee, J.S.; Lonardi, S.; Gilfillan, S.; Newberry, R.D.; Cella, M.; Colonna, M. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12-and IL-15-responsive IFN-producing cells. Immunity 2013, 38, 769-781
    • (2013) Immunity , vol.38 , pp. 769-781
    • Fuchs, A.1    Vermi, W.2    Lee, J.S.3    Lonardi, S.4    Gilfillan, S.5    Newberry, R.D.6    Cella, M.7    Colonna, M.8
  • 17
    • 84858775590 scopus 로고    scopus 로고
    • Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation
    • Halim, T.Y.F.; Krauß, R.H.; Sun, A.C.; Takei, F. Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation. Immunity 2012, 36, 451-463
    • (2012) Immunity , vol.36 , pp. 451-463
    • Halim, T.Y.F.1    Krauß, R.H.2    Sun, A.C.3    Takei, F.4
  • 18
    • 84896343916 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
    • Halim, T.Y.F.; Steer, C.A.; Mathä, L.; Gold, M.J.; Martinez-Gonzalez, I.; McNagny, K.M.; McKenzie, A.N.J.; Takei, F. Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity 2014, 40, 425-435
    • (2014) Immunity , vol.40 , pp. 425-435
    • Halim, T.Y.F.1    Steer, C.A.2    Mathä, L.3    Gold, M.J.4    Martinez-Gonzalez, I.5    McNagny, K.M.6    McKenzie, A.N.J.7    Takei, F.8
  • 19
    • 0346496018 scopus 로고    scopus 로고
    • An essential function for the nuclear receptor ROR t in the generation of fetal lymphoid tissue inducer cells
    • Eberl, G.; Marmon, S.; Sunshine, M.-J.; Rennert, P.D.; Choi, Y.; Littman, D.R. An essential function for the nuclear receptor ROR t in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 2004, 5, 64-73
    • (2004) Nat. Immunol , vol.5 , pp. 64-73
    • Eberl, G.1    Marmon, S.2    Sunshine, M.-J.3    Rennert, P.D.4    Choi, Y.5    Littman, D.R.6
  • 20
    • 57849117363 scopus 로고    scopus 로고
    • ROR t and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
    • Sanos, S.L.; Bui, V.L.; Mortha, A.; Oberle, K.; Heners, C.; Johner, C.; Diefenbach, A. ROR t and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat. Immunol. 2009, 10, 83-91
    • (2009) Nat. Immunol , vol.10 , pp. 83-91
    • Sanos, S.L.1    Bui, V.L.2    Mortha, A.3    Oberle, K.4    Heners, C.5    Johner, C.6    Diefenbach, A.7
  • 21
    • 78649360369 scopus 로고    scopus 로고
    • Regulated expression of nuclear receptor ROR t confers distinct functional fates to NK cell receptor-expressing ROR t(+) innate lymphocytes
    • Vonarbourg, C.; Mortha, A.; Bui, V.L.; Hernandez, P.P.; Kiss, E.A.; Hoyler, T.; Flach, M.; Bengsch, B.; Thimme, R.; Hölscher, C.; et al. Regulated expression of nuclear receptor ROR t confers distinct functional fates to NK cell receptor-expressing ROR t(+) innate lymphocytes. Immunity 2010, 33, 736-751
    • (2010) Immunity , vol.33 , pp. 736-751
    • Vonarbourg, C.1    Mortha, A.2    Bui, V.L.3    Hernandez, P.P.4    Kiss, E.A.5    Hoyler, T.6    Flach, M.7    Bengsch, B.8    Thimme, R.9    Hölscher, C.10
  • 24
    • 77953910523 scopus 로고    scopus 로고
    • Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue
    • Hughes, T.; Becknell, B.; Freud, A.G.; McClory, S.; Briercheck, E.; Yu, J.; Mao, C.; Giovenzana, C.; Nuovo, G.; Wei, L.; et al. Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. Immunity 2010, 32, 803-814
    • (2010) Immunity , vol.32 , pp. 803-814
    • Hughes, T.1    Becknell, B.2    Freud, A.G.3    McClory, S.4    Briercheck, E.5    Yu, J.6    Mao, C.7    Giovenzana, C.8    Nuovo, G.9    Wei, L.10
  • 25
    • 0030710079 scopus 로고    scopus 로고
    • Developing lymph nodes collect CD4+CD3-LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells
    • Mebius, R.E.; Rennert, P.; Weissman, I.L. Developing lymph nodes collect CD4+CD3-LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 1997, 7, 493-504
    • (1997) Immunity , vol.7 , pp. 493-504
    • Mebius, R.E.1    Rennert, P.2    Weissman, I.L.3
  • 33
    • 77950593165 scopus 로고    scopus 로고
    • IFN-gamma-mediated upmodulation of MHC class I expression activates tumor-specific immune response in a mouse model of prostate cancer
    • Martini, M.; Testi, M.G.; Pasetto, M.; Picchio, M.C.; Innamorati, G.; Mazzocco, M.; Ugel, S.; Cingarlini, S.; Bronte, V.; Zanovello, P.; et al. IFN-gamma-mediated upmodulation of MHC class I expression activates tumor-specific immune response in a mouse model of prostate cancer. Vaccine 2010, 28, 3548-3557
    • (2010) Vaccine , vol.28 , pp. 3548-3557
    • Martini, M.1    Testi, M.G.2    Pasetto, M.3    Picchio, M.C.4    Innamorati, G.5    Mazzocco, M.6    Ugel, S.7    Cingarlini, S.8    Bronte, V.9    Zanovello, P.10
  • 34
    • 0029799912 scopus 로고    scopus 로고
    • Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
    • Bromberg, J.F.; Horvath, C.M.; Wen, Z.; Schreiber, R.D.; Darnell, J.E. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc. Natl. Acad. Sci. USA 1996, 93, 7673-7678
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7673-7678
    • Bromberg, J.F.1    Horvath, C.M.2    Wen, Z.3    Schreiber, R.D.4    Darnell, J.E.5
  • 35
    • 0035865188 scopus 로고    scopus 로고
    • IFN-gamma-dependent inhibition of tumor angiogenesis by tumor-infiltrating CD4+ T cells requires tumor responsiveness to IFN-gamma
    • Beatty, G.; Paterson, Y. IFN-gamma-dependent inhibition of tumor angiogenesis by tumor-infiltrating CD4+ T cells requires tumor responsiveness to IFN-gamma. J. Immunol. 2001, 166, 2276-2282
    • (2001) J. Immunol , vol.166 , pp. 2276-2282
    • Beatty, G.1    Paterson, Y.2
  • 36
    • 0034913431 scopus 로고    scopus 로고
    • Interferon inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis
    • Detjen, K.M.; Farwig, K.; Welzel, M.; Wiedenmann, B.; Rosewicz, S. Interferon inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis. Gut 2001, 49, 251-262
    • (2001) Gut , vol.49 , pp. 251-262
    • Detjen, K.M.1    Farwig, K.2    Welzel, M.3    Wiedenmann, B.4    Rosewicz, S.5
  • 37
    • 17144407983 scopus 로고    scopus 로고
    • Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection
    • Whitmire, J.K.; Tan, J.T.; Whitton, J.L. Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection. J. Exp. Med. 2005, 201, 1053-1059
    • (2005) J. Exp. Med , vol.201 , pp. 1053-1059
    • Whitmire, J.K.1    Tan, J.T.2    Whitton, J.L.3
  • 38
    • 0027364337 scopus 로고
    • Interferon-A major regulator of natural killer cell-mediated cytotoxicity
    • Reiter, Z. Interferon-A major regulator of natural killer cell-mediated cytotoxicity. J. Interferon Res. 1993, 13, 247-257
    • (1993) J. Interferon Res , vol.13 , pp. 247-257
    • Reiter, Z.1
  • 39
    • 55149093640 scopus 로고    scopus 로고
    • Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms
    • Hu, X.; Chakravarty, S.D.; Ivashkiv, L.B. Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms. Immunol. Rev. 2008, 226, 41-56
    • (2008) Immunol. Rev , vol.226 , pp. 41-56
    • Hu, X.1    Chakravarty, S.D.2    Ivashkiv, L.B.3
  • 41
  • 42
    • 80053469514 scopus 로고    scopus 로고
    • The two faces of interferon-in cancer
    • Zaidi, M.R.; Merlino, G. The two faces of interferon-in cancer. Clin. Cancer Res. 2011, 17, 6118-6124
    • (2011) Clin. Cancer Res , vol.17 , pp. 6118-6124
    • Zaidi, M.R.1    Merlino, G.2
  • 43
    • 18144406858 scopus 로고    scopus 로고
    • Tumor necrosis factor reduces brain tumor growth by enhancing macrophage recruitment and microcyst formation
    • Villeneuve, J.; Tremblay, P.; Vallières, L. Tumor necrosis factor reduces brain tumor growth by enhancing macrophage recruitment and microcyst formation. Cancer Res. 2005, 65, 3928-3936
    • (2005) Cancer Res , vol.65 , pp. 3928-3936
    • Villeneuve, J.1    Tremblay, P.2    Vallières, L.3
  • 46
    • 34248222156 scopus 로고    scopus 로고
    • CD8+ T cells circumvent immune privilege in the eye and mediate intraocular tumor rejection by a TNF-alpha-dependent mechanism
    • Dace, D.S.; Chen, P.W.; Niederkorn, J.Y. CD8+ T cells circumvent immune privilege in the eye and mediate intraocular tumor rejection by a TNF-alpha-dependent mechanism. J. Immunol. 2007, 178, 6115-6122
    • (2007) J. Immunol , vol.178 , pp. 6115-6122
    • Dace, D.S.1    Chen, P.W.2    Niederkorn, J.Y.3
  • 47
    • 0027274028 scopus 로고
    • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: Monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression
    • Wu, S.; Boyer, C.M.; Whitaker, R.S.; Berchuck, A.; Wiener, J.R.; Weinberg, J.B.; Bast, R.C. Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: Monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. Cancer Res. 1993, 53, 1939-1944
    • (1993) Cancer Res , vol.53 , pp. 1939-1944
    • Wu, S.1    Boyer, C.M.2    Whitaker, R.S.3    Berchuck, A.4    Wiener, J.R.5    Weinberg, J.B.6    Bast, R.C.7
  • 49
    • 4644262855 scopus 로고    scopus 로고
    • TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?
    • Scott, K.A.; Arnott, C.H.; Robinson, S.C.; Moore, R.J.; Thompson, R.G.; Marshall, J.F.; Balkwill, F.R. TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration? Oncogene 2004, 23, 6954-6966
    • (2004) Oncogene , vol.23 , pp. 6954-6966
    • Scott, K.A.1    Arnott, C.H.2    Robinson, S.C.3    Moore, R.J.4    Thompson, R.G.5    Marshall, J.F.6    Balkwill, F.R.7
  • 50
    • 84874217880 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer
    • Wang, H.;Wang, H.-S.; Zhou, B.-H.; Li, C.-L.; Zhang, F.;Wang, X.-F.; Zhang, G.; Bu, X.-Z.; Cai, S.-H.; Du, J. Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer. PLoS ONE 2013, 8, e56664
    • (2013) PLoS ONE , vol.8
    • Wang, H.1    Wang, H.-S.2    Zhou, B.-H.3    Li, C.-L.4    Zhang, F.5    Wang, X.-F.6    Zhang, G.7    Bu, X.-Z.8    Cai, S.-H.9    Du, J.10
  • 53
    • 84936075585 scopus 로고    scopus 로고
    • CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis
    • Trabanelli, S.; Curti, A.; Lecciso, M.; Salomé, B.; Riether, C.; Ochsenbein, A.; Romero, P.; Jandus, C. CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis. Haematologica 2015, 100, e257-e260
    • (2015) Haematologica , vol.100 , pp. e257-e260
    • Trabanelli, S.1    Curti, A.2    Lecciso, M.3    Salomé, B.4    Riether, C.5    Ochsenbein, A.6    Romero, P.7    Jandus, C.8
  • 55
    • 84892612433 scopus 로고    scopus 로고
    • Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells
    • Jovanovic, I.P.; Pejnovic, N.N.; Radosavljevic, G.D.; Pantic, J.M.; Milovanovic, M.Z.; Arsenijevic, N.N.; Lukic, M.L. Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells. Int. J. Cancer 2014, 134, 1669-1682
    • (2014) Int. J. Cancer , vol.134 , pp. 1669-1682
    • Jovanovic, I.P.1    Pejnovic, N.N.2    Radosavljevic, G.D.3    Pantic, J.M.4    Milovanovic, M.Z.5    Arsenijevic, N.N.6    Lukic, M.L.7
  • 56
    • 10744220561 scopus 로고    scopus 로고
    • Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence
    • Terabe, M.; Matsui, S.; Park, J.-M.; Mamura, M.; Noben-Trauth, N.; Donaldson, D.D.; Chen, W.;Wahl, S.M.; Ledbetter, S.; Pratt, B.; et al. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence. J. Exp. Med. 2003, 198, 1741-1752
    • (2003) J. Exp. Med , vol.198 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.-M.3    Mamura, M.4    Noben-Trauth, N.5    Donaldson, D.D.6    Chen, W.7    Wahl, S.M.8    Ledbetter, S.9    Pratt, B.10
  • 60
    • 7044272630 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma in Cirrhosis: Incidence and Risk Factors
    • Fattovich, G.; Stroffolini, T.; Zagni, I.; Donato, F. Hepatocellular Carcinoma in Cirrhosis: Incidence and Risk Factors. Gastroenterology 2004, 127, S35-S50
    • (2004) Gastroenterology , vol.127 , pp. S35-S50
    • Fattovich, G.1    Stroffolini, T.2    Zagni, I.3    Donato, F.4
  • 64
    • 84930089377 scopus 로고    scopus 로고
    • The infiltration and functional regulation of eosinophils induced by TSLP promote the proliferation of cervical cancer cell
    • Xie, F.; Liu, L.-B.; Shang, W.-Q.; Chang, K.-K.; Meng, Y.-H.; Mei, J.; Yu, J.-J.; Li, D.-J.; Li, M.-Q. The infiltration and functional regulation of eosinophils induced by TSLP promote the proliferation of cervical cancer cell. Cancer Lett. 2015, 364, 106-117
    • (2015) Cancer Lett , vol.364 , pp. 106-117
    • Xie, F.1    Liu, L.-B.2    Shang, W.-Q.3    Chang, K.-K.4    Meng, Y.-H.5    Mei, J.6    Yu, J.-J.7    Li, D.-J.8    Li, M.-Q.9
  • 65
    • 84897015493 scopus 로고    scopus 로고
    • Polarization of ILC2s in peripheral blood might contribute to immunosuppressive microenvironment in patients with gastric cancer
    • Bie, Q.; Zhang, P.; Su, Z.; Zheng, D.; Ying, X.; Wu, Y.; Yang, H.; Chen, D.; Wang, S.; Xu, H. Polarization of ILC2s in peripheral blood might contribute to immunosuppressive microenvironment in patients with gastric cancer. J. Immunol. Res. 2014, 2014, 923135
    • (2014) J. Immunol. Res , vol.2014
    • Bie, Q.1    Zhang, P.2    Su, Z.3    Zheng, D.4    Ying, X.5    Wu, Y.6    Yang, H.7    Chen, D.8    Wang, S.9    Xu, H.10
  • 67
    • 33846933459 scopus 로고    scopus 로고
    • L-arginine availability regulates T-lymphocyte cell-cycle progression
    • Rodriguez, P.C.; Quiceno, D.G.; Ochoa, A.C. L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood 2007, 109, 1568-1573
    • (2007) Blood , vol.109 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 68
    • 4143130091 scopus 로고    scopus 로고
    • Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
    • Rodriguez, P.C.; Quiceno, D.G.; Zabaleta, J.; Ortiz, B.; Zea, A.H.; Piazuelo, M.B.; Delgado, A.; Correa, P.; Brayer, J.; Sotomayor, E.M.; et al. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Res. 2004, 64, 5839-5849
    • (2004) Cancer Res , vol.64 , pp. 5839-5849
    • Rodriguez, P.C.1    Quiceno, D.G.2    Zabaleta, J.3    Ortiz, B.4    Zea, A.H.5    Piazuelo, M.B.6    Delgado, A.7    Correa, P.8    Brayer, J.9    Sotomayor, E.M.10
  • 69
    • 0032102990 scopus 로고    scopus 로고
    • Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: Competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype
    • Munder, M.; Eichmann, K.; Modolell, M. Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: Competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype. J. Immunol. 1998, 160, 5347-5354
    • (1998) J. Immunol , vol.160 , pp. 5347-5354
    • Munder, M.1    Eichmann, K.2    Modolell, M.3
  • 71
    • 84887007017 scopus 로고    scopus 로고
    • Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung
    • Bando, J.K.; Nussbaum, J.C.; Liang, H.; Locksley, R.M. Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung. J. Leukoc. Biol. 2013, 94, 877-884
    • (2013) J. Leukoc. Biol , vol.94 , pp. 877-884
    • Bando, J.K.1    Nussbaum, J.C.2    Liang, H.3    Locksley, R.M.4
  • 72
    • 84940527399 scopus 로고    scopus 로고
    • IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions
    • Monticelli, L.A.; Osborne, L.C.; Noti, M.; Tran, S.V.; Zaiss, D.M.W.; Artis, D. IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions. Proc. Natl. Acad. Sci. USA 2015, 112, 10762-10767
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 10762-10767
    • Monticelli, L.A.1    Osborne, L.C.2    Noti, M.3    Tran, S.V.4    Zaiss, D.M.W.5    Artis, D.6
  • 75
    • 84907953760 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice
    • Drake, L.Y.; Iijima, K.; Kita, H. Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice. Allergy 2014, 69, 1300-1307
    • (2014) Allergy , vol.69 , pp. 1300-1307
    • Drake, L.Y.1    Iijima, K.2    Kita, H.3
  • 77
    • 84907370454 scopus 로고    scopus 로고
    • MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion
    • Oliphant, C.J.; Hwang, Y.Y.;Walker, J.A.; Salimi, M.;Wong, S.H.; Brewer, J.M.; Englezakis, A.; Barlow, J.L.; Hams, E.; Scanlon, S.T.; et al. MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion. Immunity 2014, 41, 283-295
    • (2014) Immunity , vol.41 , pp. 283-295
    • Oliphant, C.J.1    Hwang, Y.Y.2    Walker, J.A.3    Salimi, M.4    Wong, S.H.5    Brewer, J.M.6    Englezakis, A.7    Barlow, J.L.8    Hams, E.9    Scanlon, S.T.10
  • 80
    • 84903442371 scopus 로고    scopus 로고
    • Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet.Rag2 (TRUC) mice
    • Ermann, J.; Staton, T.; Glickman, J.N.; de Waal Malefyt, R.; Glimcher, L.H. Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet.Rag2 (TRUC) mice. Proc. Natl. Acad. Sci. USA 2014, 111, E2559-E2566
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E2559-E2566
    • Ermann, J.1    Staton, T.2    Glickman, J.N.3    de Waal Malefyt, R.4    Glimcher, L.H.5
  • 83
    • 69249161777 scopus 로고    scopus 로고
    • Colorectal cancer and inflammatory bowel disease: Epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies
    • Triantafillidis, J.K.; Nasioulas, G.; Kosmidis, P.A. Colorectal cancer and inflammatory bowel disease: Epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies. Anticancer Res. 2009, 29, 2727-2737
    • (2009) Anticancer Res , vol.29 , pp. 2727-2737
    • Triantafillidis, J.K.1    Nasioulas, G.2    Kosmidis, P.A.3
  • 86
    • 84902573427 scopus 로고    scopus 로고
    • Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells
    • Chan, I.H.; Jain, R.; Tessmer, M.S.; Gorman, D.; Mangadu, R.; Sathe, M.; Vives, F.; Moon, C.; Penaflor, E.; Turner, S.; et al. Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunol. 2014, 7, 842-856
    • (2014) Mucosal Immunol , vol.7 , pp. 842-856
    • Chan, I.H.1    Jain, R.2    Tessmer, M.S.3    Gorman, D.4    Mangadu, R.5    Sathe, M.6    Vives, F.7    Moon, C.8    Penaflor, E.9    Turner, S.10
  • 87
    • 79953681584 scopus 로고    scopus 로고
    • IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma
    • Liu, J.; Duan, Y.; Cheng, X.; Chen, X.; Xie, W.; Long, H.; Lin, Z.; Zhu, B. IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem. Biophys. Res. Commun. 2011, 407, 348-354
    • (2011) Biochem. Biophys. Res. Commun , vol.407 , pp. 348-354
    • Liu, J.1    Duan, Y.2    Cheng, X.3    Chen, X.4    Xie, W.5    Long, H.6    Lin, Z.7    Zhu, B.8
  • 89
    • 84946567263 scopus 로고    scopus 로고
    • Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
    • Pan, B.; Shen, J.; Cao, J.; Zhou, Y.; Shang, L.; Jin, S.; Cao, S.; Che, D.; Liu, F.; Yu, Y. Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer. Sci. Rep. 2015, 5, 16053
    • (2015) Sci. Rep , vol.5 , pp. 16053
    • Pan, B.1    Shen, J.2    Cao, J.3    Zhou, Y.4    Shang, L.5    Jin, S.6    Cao, S.7    Che, D.8    Liu, F.9    Yu, Y.10
  • 90
    • 82255164625 scopus 로고    scopus 로고
    • Distribution and clinical significance of Th17 cells in the tumor microenvironment and peripheral blood of pancreatic cancer patients
    • He, S.; Fei, M.; Wu, Y.; Zheng, D.; Wan, D.; Wang, L.; Li, D. Distribution and clinical significance of Th17 cells in the tumor microenvironment and peripheral blood of pancreatic cancer patients. Int. J. Mol. Sci. 2011, 12, 7424-7437
    • (2011) Int. J. Mol. Sci , vol.12 , pp. 7424-7437
    • He, S.1    Fei, M.2    Wu, Y.3    Zheng, D.4    Wan, D.5    Wang, L.6    Li, D.7
  • 91
    • 64549108462 scopus 로고    scopus 로고
    • Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
    • Zhang, J.-P.; Yan, J.; Xu, J.; Pang, X.-H.; Chen, M.-S.; Li, L.; Wu, C.; Li, S.-P.; Zheng, L. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J. Hepatol. 2009, 50, 980-989
    • (2009) J. Hepatol , vol.50 , pp. 980-989
    • Zhang, J.-P.1    Yan, J.2    Xu, J.3    Pang, X.-H.4    Chen, M.-S.5    Li, L.6    Wu, C.7    Li, S.-P.8    Zheng, L.9
  • 92
    • 85035078796 scopus 로고    scopus 로고
    • IL-17 promotes tumor angiogenesis through Stat3 pathway mediated upregulation of VEGF in gastric cancer
    • Wu, X.; Yang, T.; Liu, X.; Guo, J.N.; Xie, T.; Ding, Y.; Lin, M.; Yang, H. IL-17 promotes tumor angiogenesis through Stat3 pathway mediated upregulation of VEGF in gastric cancer. Tumor Biol. 2015
    • (2015) Tumor Biol
    • Wu, X.1    Yang, T.2    Liu, X.3    Guo, J.N.4    Xie, T.5    Ding, Y.6    Lin, M.7    Yang, H.8
  • 93
    • 77951936316 scopus 로고    scopus 로고
    • IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells
    • He, D.; Li, H.; Yusuf, N.; Elmets, C.A.; Li, J.; Mountz, J.D.; Xu, H. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J. Immunol. 2010, 184, 2281-2288
    • (2010) J. Immunol , vol.184 , pp. 2281-2288
    • He, D.1    Li, H.2    Yusuf, N.3    Elmets, C.A.4    Li, J.5    Mountz, J.D.6    Xu, H.7
  • 94
    • 84890905720 scopus 로고    scopus 로고
    • Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid
    • Martin, J.C.J.; Bériou, G.; Heslan, M.; Chauvin, C.; Utriainen, L.; Aumeunier, A.; Scott, C.L.; Mowat, A.; Cerovic, V.; Houston, S.A.; et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol. 2014, 7, 101-113
    • (2014) Mucosal Immunol , vol.7 , pp. 101-113
    • Martin, J.C.J.1    Bériou, G.2    Heslan, M.3    Chauvin, C.4    Utriainen, L.5    Aumeunier, A.6    Scott, C.L.7    Mowat, A.8    Cerovic, V.9    Houston, S.A.10
  • 95
    • 84880923452 scopus 로고    scopus 로고
    • Interleukin-22 is frequently expressed in small-and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells
    • Kobold, S.; Völk, S.; Clauditz, T.; Küpper, N.J.; Minner, S.; Tufman, A.; Düwell, P.; Lindner, M.; Koch, I.; Heidegger, S.; et al. Interleukin-22 is frequently expressed in small-and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells. J. Thorac. Oncol. 2013, 8, 1032-1042
    • (2013) J. Thorac. Oncol , vol.8 , pp. 1032-1042
    • Kobold, S.1    Völk, S.2    Clauditz, T.3    Küpper, N.J.4    Minner, S.5    Tufman, A.6    Düwell, P.7    Lindner, M.8    Koch, I.9    Heidegger, S.10
  • 101
    • 67651094058 scopus 로고    scopus 로고
    • Endogenous IL-17 contributes to reduced tumor growth and metastasis
    • Kryczek, I.; Wei, S.; Szeliga, W.; Vatan, L.; Zou, W. Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 2009, 114, 357-359
    • (2009) Blood , vol.114 , pp. 357-359
    • Kryczek, I.1    Wei, S.2    Szeliga, W.3    Vatan, L.4    Zou, W.5
  • 102
    • 33751564062 scopus 로고    scopus 로고
    • IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase
    • Weber, G.F.; Gaertner, F.C.; Erl, W.; Janssen, K.-P.; Blechert, B.; Holzmann, B.; Weighardt, H.; Essler, M. IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase. J. Immunol. 2006, 177, 8266-8272
    • (2006) J. Immunol , vol.177 , pp. 8266-8272
    • Weber, G.F.1    Gaertner, F.C.2    Erl, W.3    Janssen, K.-P.4    Blechert, B.5    Holzmann, B.6    Weighardt, H.7    Essler, M.8
  • 104
    • 77958153282 scopus 로고    scopus 로고
    • IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46
    • Eisenring, M.; Berg, J.; Kristiansen, G.; Saller, E.; Becher, B. IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat. Immunol. 2010, 11, 1030-1038
    • (2010) Nat. Immunol , vol.11 , pp. 1030-1038
    • Eisenring, M.1    Berg, J.2    Kristiansen, G.3    Saller, E.4    Becher, B.5
  • 107
    • 77952231121 scopus 로고    scopus 로고
    • Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
    • Shields, J.D.; Kourtis, I.C.; Tomei, A.A.; Roberts, J.M.; Swartz, M.A. Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 2010, 328, 749-752
    • (2010) Science , vol.328 , pp. 749-752
    • Shields, J.D.1    Kourtis, I.C.2    Tomei, A.A.3    Roberts, J.M.4    Swartz, M.A.5
  • 108
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman, R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991, 9, 271-296
    • (1991) Annu. Rev. Immunol , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 109
    • 84918774816 scopus 로고    scopus 로고
    • Dendritic cell cross talk with innate and innate-like effector cells in antitumor immunity: Implications for DC vaccination
    • Van Beek, J.J.P.; Wimmers, F.; Hato, S.V.; de Vries, I.J.M.; Sköld, A.E. Dendritic cell cross talk with innate and innate-like effector cells in antitumor immunity: Implications for DC vaccination. Crit. Rev. Immunol. 2014, 34, 517-536
    • (2014) Crit. Rev. Immunol , vol.34 , pp. 517-536
    • Van Beek, J.J.P.1    Wimmers, F.2    Hato, S.V.3    de Vries, I.J.M.4    Sköld, A.E.5
  • 111
    • 84857444876 scopus 로고    scopus 로고
    • Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense
    • Kinnebrew, M.A.; Buffie, C.G.; Diehl, G.E.; Zenewicz, L.A.; Leiner, I.; Hohl, T.M.; Flavell, R.A.; Littman, D.R.; Pamer, E.G. Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense. Immunity 2012, 36, 276-287
    • (2012) Immunity , vol.36 , pp. 276-287
    • Kinnebrew, M.A.1    Buffie, C.G.2    Diehl, G.E.3    Zenewicz, L.A.4    Leiner, I.5    Hohl, T.M.6    Flavell, R.A.7    Littman, D.R.8    Pamer, E.G.9
  • 112
    • 84905098795 scopus 로고    scopus 로고
    • Human innate lymphoid cells
    • Hazenberg, M.D.; Spits, H. Human innate lymphoid cells. Blood 2014, 124, 700-709
    • (2014) Blood , vol.124 , pp. 700-709
    • Hazenberg, M.D.1    Spits, H.2
  • 113
    • 84902191817 scopus 로고    scopus 로고
    • IL-2: The first effective immunotherapy for human cancer
    • Rosenberg, S.A. IL-2: The first effective immunotherapy for human cancer. J. Immunol. 2014, 192, 5451-5458
    • (2014) J. Immunol , vol.192 , pp. 5451-5458
    • Rosenberg, S.A.1
  • 114
  • 115
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll, D.M. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 2012, 12, 252-264
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 116
    • 77957701558 scopus 로고    scopus 로고
    • The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody
    • Benson, D.M.; Bakan, C.E.; Mishra, A.; Hofmeister, C.C.; Efebera, Y.; Becknell, B.; Baiocchi, R.A.; Zhang, J.; Yu, J.; Smith, M.K.; et al. The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood 2010, 116, 2286-2294
    • (2010) Blood , vol.116 , pp. 2286-2294
    • Benson, D.M.1    Bakan, C.E.2    Mishra, A.3    Hofmeister, C.C.4    Efebera, Y.5    Becknell, B.6    Baiocchi, R.A.7    Zhang, J.8    Yu, J.9    Smith, M.K.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.