Erratum: Human hepatic organoids for the analysis of human genetic diseases (JCI Insight. (2017) 2:17 (e94954) DOI: 10.1172/jci.insight.94954);Human hepatic organoids for the analysis of human genetic diseases

JCI Insight

Volumn 2, Issue 17, 2017, Pages

  Guan, Yuan ^a   Xu, Dan ^a   Garfin, Phillip M ^a   Ehmer, Ursula ^a   Hurwitz, Melissa ^a   Enns, Greg ^a   Michie, Sara ^a   Wu, Manhong ^a   Zheng, Ming ^a   Nishimura, Toshihiko ^a,b,c   Sage, Julien ^a   Peltz, Gary ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Center for the Advancement of Health and Bioscience   (United States)

^c CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85044462649     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.176034     Document Type: Erratum

References (61)

1. Zaret KS. Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation. Nat Rev Genet. 2008;9(5):329–340.
2. Oda T, et al. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat Genet. 1997;16(3):235–242.
3. Li L, et al. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet. 1997;16(3):243–251.
4. Penton AL, Leonard LD, Spinner NB. Notch signaling in human development and disease. Semin Cell Dev Biol. 2012;23(4):450–457.
5. Kamath BM, Bason L, Piccoli DA, Krantz ID, Spinner NB. Consequences of JAG1 mutations. J Med Genet. 2003;40(12):891–895.
6. Fallot ELA. Contribution a` l’anatomie pathologique de la maladie bleue (cyanose cardiaque). Marsaille Medical. 1881;25:77–95.
7. Emerick KM, Rand EB, Goldmuntz E, Krantz ID, Spinner NB, Piccoli DA. Features of Alagille syndrome in 92 patients: frequency and relation to prognosis. Hepatology. 1999;29(3):822–829.
8. Anderson RH, Spicer DE, Giroud JM, Mohun TJ. Tetralogy of Fallot: nosological, morphological, and morphogenetic considerations. Cardiol Young. 2013;23(6):858–866.
9. Krantz ID, et al. Jagged1 mutations in patients ascertained with isolated congenital heart defects. Am J Med Genet. 1999;84(1):56–60.
10. Artavanis-Tsakonas S, Matsuno K, Fortini ME. Notch signaling. Science. 1995;268(5208):225–232.
11. Guruharsha KG, Kankel MW, Artavanis-Tsakonas S. The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat Rev Genet. 2012;13(9):654–666.
12. Fleming RJ, Purcell K, Artavanis-Tsakonas S. The NOTCH receptor and its ligands. Trends Cell Biol. 1997;7(11):437–441.
13. Kodama Y, Hijikata M, Kageyama R, Shimotohno K, Chiba T. The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology. 2004;127(6):1775–1786.
14. Lorent K, et al. Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy. Development. 2004;131(22):5753–5766.
15. Zender S, et al. A critical role for notch signaling in the formation of cholangiocellular carcinomas. Cancer Cell. 2013;23(6):784–795.
16. Sekiya S, Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest. 2012;122(11):3914–3918.
17. Crawford JM. Development of the intrahepatic biliary tree. Semin Liver Dis. 2002;22(3):213–226.
18. Crosnier C, et al. JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome. Hepatology. 2000;32(3):574–581.
19. Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML. Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010;137(23):4061–4072.
20. Sparks EE, Huppert KA, Brown MA, Washington MK, Huppert SS. Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology. 2010;51(4):1391–1400.
21. McCright B, Lozier J, Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development. 2002;129(4):1075–1082.
22. Xue Y, et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet. 1999;8(5):723–730.
23. Thakurdas SM, et al. Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi). Hepatology. 2016;63(2):550–565.
24. Deleuze JF, Hazan J, Dhorne S, Weissenbach J, Hadchouel M. Mapping of microsatellite markers in the Alagille region and screening of microdeletions by genotyping 23 patients. Eur J Hum Genet. 1994;2(3):185–190.
25. Desmaze C, Deleuze JF, Dutrillaux AM, Thomas G, Hadchouel M, Aurias A. Screening of microdeletions of chromosome 20 in patients with Alagille syndrome. J Med Genet. 1992;29(4):233–235.
26. Deleuze JF, et al. Deleted chromosome 20 from a patient with Alagille syndrome isolated in a cell hybrid through leucine transport selection: study of three candidate genes. Mamm Genome. 1994;5(11):663–669.
27. Spinner NB, Colliton RP, Crosnier C, Krantz ID, Hadchouel M, Meunier-Rotival M. Jagged1 mutations in alagille syndrome. Hum Mutat. 2001;17(1):18–33.
28. Grochowski CM, Loomes KM, Spinner NB. Jagged1 (JAG1): Structure, expression, and disease associations. Gene. 2016;576(1 Pt 3):381–384.
29. Lu F, Morrissette JJ, Spinner NB. Conditional JAG1 mutation shows the developing heart is more sensitive than developing liver to JAG1 dosage. Am J Hum Genet. 2003;72(4):1065–1070.
30. Hannan NR, Segeritz CP, Touboul T, Vallier L. Production of hepatocyte-like cells from human pluripotent stem cells. Nat Protoc. 2013;8(2):430–437.
31. Huch M, et al. Long-term culture of genome-stable bipotent stem cells from adult human liver. Cell. 2015;160(1–2):299–312.
32. Nakano T, et al. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell. 2012;10(6):771–785.
33. Dong PD, et al. Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nat Genet. 2007;39(3):397–402.
34. Suzuki A, Sekiya S, Büscher D, Izpisúa Belmonte JC, Taniguchi H. Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development. 2008;135(9):1589–1595.
35. Shiojiri N. The origin of intrahepatic bile duct cells in the mouse. J Embryol Exp Morphol. 1984;79:25–39.
36. Nishimura T, et al. Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther. 2013;344(2):388–396.
37. Landing BH, Wells TR. Considerations of Some Architectural Properties of the Biliary Tree and Liver in Childhood. In: Abramowsky CR, Rosenberg BJ eds. Transplantation Pathology-Hepatic Morphogenesis. Basel: Kruger; 1981:122–42.
38. Landing BH, Wells TR. Considerations of some architectural properties of the biliary tree and liver in childhood. Perspect Pediatr Pathol. 1991;14:122–142.
39. Furuyama K, et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011;43(1):34–41.
40. Boulter L, et al. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med. 2012;18(4):572–579.
41. D’Souza B, Meloty-Kapella L, Weinmaster G. Canonical and non-canonical Notch ligands. Curr Top Dev Biol. 2010;92:73–129.
42. Hammad S, et al. Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis. ArchToxicol. 2014;88(5):1161–1183.
43. Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol. 2003;194(3):237–255.
44. Gigliozzi A, et al. Molecular identification and functional characterization of Mdr1a in rat cholangiocytes. Gastroenterology. 2000;119(4):1113–1122.
45. Eldadah ZA, et al. Familial Tetralogy of Fallot caused by mutation in the jagged1 gene. Hum Mol Genet. 2001;10(2):163–169.
46. Sia D, et al. Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nat Commun. 2015;6:6087.
47. McCauley HA, Wells JM. Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish. Development. 2017;144(6):958–962.
48. Rashid ST, et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest. 2010;120(9):3127–3136.
49. Ogawa M, et al. Directed differentiation of cholangiocytes from human pluripotent stem cells. Nat Biotechnol. 2015;33(8):853–861.
50. Sampaziotis F, et al. Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation. Nat Biotechnol. 2015;33(8):845–852.
51. Strazzabosco M, Fabris L. Development of the bile ducts: essentials for the clinical hepatologist. J Hepatol. 2012;56(5):1159–1170.
52. Dahms BB, et al. Arteriohepatic dysplasia in infancy and childhood: a longitudinal study of six patients. Hepatology. 1982;2(3):350–358.
53. Kahn EI, et al. Arteriohepatic dysplasia. II. Hepatobiliary morphology. Hepatology. 1983;3(1):77–84.
54. Carpentier R, et al. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011;141(4):1432–8, 1438.e1.
55. Crawford LW, Foley JF, Elmore SA. Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5. Toxicol Pathol. 2010;38(6):872–906.
56. Libbrecht L, Spinner NB, Moore EC, Cassiman D, Van Damme-Lombaerts R, Roskams T. Peripheral bile duct paucity and cholestasis in the liver of a patient with Alagille syndrome: further evidence supporting a lack of postnatal bile duct branching and elongation. Am J Surg Pathol. 2005;29(6):820–826.
57. Fabris L, et al. Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling. Am J Pathol. 2007;171(2):641–653.
58. Croquelois A, et al. Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology. 2005;41(3):487–496.
59. Jörs S, et al. Lineage fate of ductular reactions in liver injury and carcinogenesis. J Clin Invest. 2015;125(6):2445–2457.
60. Pardo-Saganta A, et al. Parent stem cells can serve as niches for their daughter cells. Nature. 2015;523(7562):597–601.
61. Hockemeyer D, Jaenisch R. Induced pluripotent stem cells meet genome editing. Cell Stem Cell. 2016;18(5):573–586.