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Volumn 153, Issue , 2018, Pages 85-94

Favipiravir as a potential countermeasure against neglected and emerging RNA viruses

Author keywords

[No Author keywords available]

Indexed keywords

FAVIPIRAVIR; RNA POLYMERASE; VIRUS RNA; AMIDE; ANTIVIRUS AGENT; PYRAZINE DERIVATIVE;

EID: 85044444590     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2018.03.003     Document Type: Review
Times cited : (300)

References (76)
  • 1
    • 85034963814 scopus 로고    scopus 로고
    • Antiviral treatment efficiently inhibits chikungunya virus infection in the joints of mice during the acute but not during the chronic phase of the infection
    • Abdelnabi, R., Jochmans, D., Verbeken, E., Neyts, J., Delang, L., Antiviral treatment efficiently inhibits chikungunya virus infection in the joints of mice during the acute but not during the chronic phase of the infection. Antivir. Res., 2017 https://doi.org/10.1016/j.antiviral.2017.09.016.
    • (2017) Antivir. Res.
    • Abdelnabi, R.1    Jochmans, D.2    Verbeken, E.3    Neyts, J.4    Delang, L.5
  • 2
    • 85019750229 scopus 로고    scopus 로고
    • Understanding the mechanism of the broad-spectrum antiviral activity of favipiravir (T-705): key role of the F1 motif of the viral polymerase
    • e00487–17
    • Abdelnabi, R., Morais, A.T.S., De Leyssen, P., Imbert, I., Beaucourt, S., Blanc, H., Froeyen, M., Vignuzzi, M., Canard, B., Neyts, J., Delang, L., Understanding the mechanism of the broad-spectrum antiviral activity of favipiravir (T-705): key role of the F1 motif of the viral polymerase. J. Virol., 91, 2017 e00487–17 https://doi.org/10.1128/JVI.00487-17.
    • (2017) J. Virol. , vol.91
    • Abdelnabi, R.1    Morais, A.T.S.2    De Leyssen, P.3    Imbert, I.4    Beaucourt, S.5    Blanc, H.6    Froeyen, M.7    Vignuzzi, M.8    Canard, B.9    Neyts, J.10    Delang, L.11
  • 3
    • 84924773343 scopus 로고    scopus 로고
    • Favipiravir elicits antiviral mutagenesis during virus replication in vivo
    • Arias, A., Thorne, L., Goodfellow, I., Favipiravir elicits antiviral mutagenesis during virus replication in vivo. Elife, 3, 2014, e03679 https://doi.org/10.7554/eLife.03679.
    • (2014) Elife , vol.3 , pp. e03679
    • Arias, A.1    Thorne, L.2    Goodfellow, I.3
  • 7
    • 84875107202 scopus 로고    scopus 로고
    • T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
    • Baranovich, T., Wong, S.-S., Armstrong, J., Marjuki, H., Webby, R.J., Webster, R.G., Govorkova, E.A., T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro. J. Virol. 87 (2013), 3741–3751 https://doi.org/10.1128/JVI.02346-12.
    • (2013) J. Virol. , vol.87 , pp. 3741-3751
    • Baranovich, T.1    Wong, S.-S.2    Armstrong, J.3    Marjuki, H.4    Webby, R.J.5    Webster, R.G.6    Govorkova, E.A.7
  • 8
    • 85038851247 scopus 로고    scopus 로고
    • In vitro susceptibility of geographically and temporally distinct zika viruses to favipiravir and ribavirin
    • Baz, M., Goyette, N., Griffin, B.D., Kobinger, G.P., Boivin, G., In vitro susceptibility of geographically and temporally distinct zika viruses to favipiravir and ribavirin. Antivir. Ther., 2017 https://doi.org/10.3851/IMP3180.
    • (2017) Antivir. Ther.
    • Baz, M.1    Goyette, N.2    Griffin, B.D.3    Kobinger, G.P.4    Boivin, G.5
  • 11
    • 0037386414 scopus 로고    scopus 로고
    • A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases
    • Bruenn, J.A., A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases. Nucleic Acids Res. 31 (2003), 1821–1829 https://doi.org/10.1093/nar/gkg277.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 1821-1829
    • Bruenn, J.A.1
  • 12
    • 80053329255 scopus 로고    scopus 로고
    • Maporal virus as a surrogate for pathogenic New World hantaviruses and its inhibition by favipiravir
    • Buys, K.K., Jung, K.H., Smee, D.F., Furuta, Y., Gowen, B.B., Maporal virus as a surrogate for pathogenic New World hantaviruses and its inhibition by favipiravir. Antivir. Chem. Chemother. 21 (2011), 193–200 https://doi.org/10.3851/IMP1729.
    • (2011) Antivir. Chem. Chemother. , vol.21 , pp. 193-200
    • Buys, K.K.1    Jung, K.H.2    Smee, D.F.3    Furuta, Y.4    Gowen, B.B.5
  • 13
    • 85020448380 scopus 로고    scopus 로고
    • Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication
    • Cai, L., Sun, Y., Song, Y., Xu, L., Bei, Z., Zhang, D., Dou, Y., Wang, H., Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication. Arch. Virol. 162 (2017), 2847–2853 https://doi.org/10.1007/s00705-017-3436-8.
    • (2017) Arch. Virol. , vol.162 , pp. 2847-2853
    • Cai, L.1    Sun, Y.2    Song, Y.3    Xu, L.4    Bei, Z.5    Zhang, D.6    Dou, Y.7    Wang, H.8
  • 14
    • 84919794244 scopus 로고    scopus 로고
    • Characterization of susceptibility variants of influenza virus grown in the presence of T-705
    • Daikoku, T., Yoshida, Y., Okuda, T., Shiraki, K., Characterization of susceptibility variants of influenza virus grown in the presence of T-705. J. Pharmacol. Sci. 126 (2014), 281–284 https://doi.org/10.1254/jphs.14156SC.
    • (2014) J. Pharmacol. Sci. , vol.126 , pp. 281-284
    • Daikoku, T.1    Yoshida, Y.2    Okuda, T.3    Shiraki, K.4
  • 16
    • 85016158332 scopus 로고    scopus 로고
    • Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus
    • de Avila, A.I., Moreno, E., Perales, C., Domingo, E., Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus. Virus Res. 233 (2017), 105–112 https://doi.org/10.1016/j.virusres.2017.03.014.
    • (2017) Virus Res. , vol.233 , pp. 105-112
    • de Avila, A.I.1    Moreno, E.2    Perales, C.3    Domingo, E.4
  • 21
    • 85026639600 scopus 로고    scopus 로고
    • Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase
    • Furuta, Y., Komeno, T., Nakamura, T., Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase. Proc. Jpn. Acad. Ser. B 93 (2017), 449–463 https://doi.org/10.2183/pjab.93.027.
    • (2017) Proc. Jpn. Acad. Ser. B , vol.93 , pp. 449-463
    • Furuta, Y.1    Komeno, T.2    Nakamura, T.3
  • 25
    • 84937862862 scopus 로고    scopus 로고
    • Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever
    • Gowen, B.B., Sefing, E.J., Westover, J.B., Smee, D.F., Hagloch, J., Furuta, Y., Hall, J.O., Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever. Antivir. Res. 121 (2015), 132–137 https://doi.org/10.1016/j.antiviral.2015.07.003.
    • (2015) Antivir. Res. , vol.121 , pp. 132-137
    • Gowen, B.B.1    Sefing, E.J.2    Westover, J.B.3    Smee, D.F.4    Hagloch, J.5    Furuta, Y.6    Hall, J.O.7
  • 26
    • 85010903526 scopus 로고    scopus 로고
    • Modeling severe fever with thrombocytopenia syndrome virus infection in golden Syrian hamsters: importance of STAT2 in preventing disease and effective treatment with favipiravir
    • Gowen, B.B., Westover, J.B., Miao, J., Van Wettere, A.J., Rigas, J.D., Hickerson, B.T., Jung, K.-H., Li, R., Conrad, B.L., Nielson, S., Furuta, Y., Wang, Z., Modeling severe fever with thrombocytopenia syndrome virus infection in golden Syrian hamsters: importance of STAT2 in preventing disease and effective treatment with favipiravir. J. Virol. 91 (2017), 1–12 https://doi.org/10.1128/JVI.01942-16.
    • (2017) J. Virol. , vol.91 , pp. 1-12
    • Gowen, B.B.1    Westover, J.B.2    Miao, J.3    Van Wettere, A.J.4    Rigas, J.D.5    Hickerson, B.T.6    Jung, K.-H.7    Li, R.8    Conrad, B.L.9    Nielson, S.10    Furuta, Y.11    Wang, Z.12
  • 27
    • 85026803822 scopus 로고    scopus 로고
    • Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy
    • Gowen, B.B., Westover, J.B., Sefing, E.J., Van Wettere, A.J., Bailey, K.W., Wandersee, L., Komeno, T., Furuta, Y., Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy. Antivir. Res. 145 (2017), 131–135 https://doi.org/10.1016/j.antiviral.2017.07.019.
    • (2017) Antivir. Res. , vol.145 , pp. 131-135
    • Gowen, B.B.1    Westover, J.B.2    Sefing, E.J.3    Van Wettere, A.J.4    Bailey, K.W.5    Wandersee, L.6    Komeno, T.7    Furuta, Y.8
  • 31
    • 84880006467 scopus 로고    scopus 로고
    • The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5’-triphosphate towards influenza A virus polymerase
    • Jin, Z., Smith, L.K., Rajwanshi, V.K., Kim, B., Deval, J., The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5’-triphosphate towards influenza A virus polymerase. PLoS One, 8, 2013, e68347 https://doi.org/10.1371/journal.pone.0068347.
    • (2013) PLoS One , vol.8 , pp. e68347
    • Jin, Z.1    Smith, L.K.2    Rajwanshi, V.K.3    Kim, B.4    Deval, J.5
  • 33
    • 84979502266 scopus 로고    scopus 로고
    • Antiviral activity of favipiravir (T-705) against a broad range of paramyxoviruses in vitro and against human metapneumovirus in hamsters
    • Jochmans, D., Van Nieuwkoop, S., Smits, S.L., Neyts, J., Fouchier, R.A.M., Van Den Hoogen, B.G., Antiviral activity of favipiravir (T-705) against a broad range of paramyxoviruses in vitro and against human metapneumovirus in hamsters. Antimicrob. Agents Chemother. 60 (2016), 4620–4629 https://doi.org/10.1128/AAC.00709-16.
    • (2016) Antimicrob. Agents Chemother. , vol.60 , pp. 4620-4629
    • Jochmans, D.1    Van Nieuwkoop, S.2    Smits, S.L.3    Neyts, J.4    Fouchier, R.A.M.5    Van Den Hoogen, B.G.6
  • 34
    • 59749106534 scopus 로고    scopus 로고
    • Activity of T-705 in a hamster model of yellow fever virus infection in comparison with that of a chemically related compound, T-1106
    • Julander, J.G., Shafer, K., Smee, D.F., Morrey, J.D., Furuta, Y., Activity of T-705 in a hamster model of yellow fever virus infection in comparison with that of a chemically related compound, T-1106. Antimicrob. Agents Chemother. 53 (2009), 202–209 https://doi.org/10.1128/AAC.01074-08.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 202-209
    • Julander, J.G.1    Shafer, K.2    Smee, D.F.3    Morrey, J.D.4    Furuta, Y.5
  • 35
    • 64749095802 scopus 로고    scopus 로고
    • Effect of T-705 treatment on western equine encephalitis in a mouse model
    • Julander, J.G., Smee, D.F., Morrey, J.D., Furuta, Y., Effect of T-705 treatment on western equine encephalitis in a mouse model. Antivir. Res. 82 (2009), 169–171 https://doi.org/10.1016/j.antiviral.2009.02.201.
    • (2009) Antivir. Res. , vol.82 , pp. 169-171
    • Julander, J.G.1    Smee, D.F.2    Morrey, J.D.3    Furuta, Y.4
  • 36
    • 85041913498 scopus 로고    scopus 로고
    • Favipiravir and ribavirin inhibit replication of Asian and African strains of zika virus in different cell models
    • Kim, J.-A., Seong, R.-K., Kumar, M., Shin, O.S., Favipiravir and ribavirin inhibit replication of Asian and African strains of zika virus in different cell models. Viruses, 10(72), 2018 https://doi.org/10.3390/v10020072.
    • (2018) Viruses , vol.10 , Issue.72
    • Kim, J.-A.1    Seong, R.-K.2    Kumar, M.3    Shin, O.S.4
  • 37
    • 85026325695 scopus 로고    scopus 로고
    • Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals
    • Lanko, K., Eggermont, K., Patel, A., Kaptein, S., Delang, L., Verfaillie, C.M., Neyts, J., Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals. Antivir. Res. 145 (2017), 82–86 https://doi.org/10.1016/j.antiviral.2017.07.010.
    • (2017) Antivir. Res. , vol.145 , pp. 82-86
    • Lanko, K.1    Eggermont, K.2    Patel, A.3    Kaptein, S.4    Delang, L.5    Verfaillie, C.M.6    Neyts, J.7
  • 39
    • 84955304814 scopus 로고    scopus 로고
    • Ebola virus infection: review of the pharmacokinetic and pharmacodynamic properties of drugs considered for testing in human efficacy trials
    • Madelain, V., Nguyen, T.H.T., Olivo, A., de Lamballerie, X., Guedj, J., Taburet, A.M., Mentré F., Ebola virus infection: review of the pharmacokinetic and pharmacodynamic properties of drugs considered for testing in human efficacy trials. Clin. Pharmacokinet., 2016 https://doi.org/10.1007/s40262-015-0364-1.
    • (2016) Clin. Pharmacokinet.
    • Madelain, V.1    Nguyen, T.H.T.2    Olivo, A.3    de Lamballerie, X.4    Guedj, J.5    Taburet, A.M.6    Mentré, F.7
  • 40
    • 84969416041 scopus 로고    scopus 로고
    • A rapid screening assay identifies monotherapy with interferon-ß and combination therapies with nucleoside analogs as effective inhibitors of Ebola virus
    • McCarthy, S.D.S., Majchrzak-Kita, B., Racine, T., Kozlowski, H.N., Baker, D.P., Hoenen, T., Kobinger, G.P., Fish, E.N., Branch, D.R., A rapid screening assay identifies monotherapy with interferon-ß and combination therapies with nucleoside analogs as effective inhibitors of Ebola virus. PLoS Negl. Trop. Dis., 10, 2016 https://doi.org/10.1371/journal.pntd.0004364.
    • (2016) PLoS Negl. Trop. Dis. , vol.10
    • McCarthy, S.D.S.1    Majchrzak-Kita, B.2    Racine, T.3    Kozlowski, H.N.4    Baker, D.P.5    Hoenen, T.6    Kobinger, G.P.7    Fish, E.N.8    Branch, D.R.9
  • 41
    • 85011104619 scopus 로고    scopus 로고
    • Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults
    • NCT02008344. [WWW Document]
    • MDVI, Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults. NCT02008344. [WWW Document], 2013 https://clinicaltrials.gov/ct2/show/NCT02008344.
    • (2013)
    • MDVI1
  • 43
    • 80055080528 scopus 로고    scopus 로고
    • Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic fever
    • Mendenhall, M., Russell, A., Smee, D.F., Hall, J.O., Skirpstunas, R., Furuta, Y., Gowen, B.B., Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic fever. PLoS Negl. Trop. Dis. 5 (2011), 1–10 https://doi.org/10.1371/journal.pntd.0001342.
    • (2011) PLoS Negl. Trop. Dis. , vol.5 , pp. 1-10
    • Mendenhall, M.1    Russell, A.2    Smee, D.F.3    Hall, J.O.4    Skirpstunas, R.5    Furuta, Y.6    Gowen, B.B.7
  • 45
    • 56349130559 scopus 로고    scopus 로고
    • Efficacy of orally administered T-705 pyrazine analog on lethal West Nile virus infection in rodents
    • Morrey, J.D., Taro, B.S., Siddharthan, V., Wang, H., Smee, D.F., Christensen, A.J., Furuta, Y., Efficacy of orally administered T-705 pyrazine analog on lethal West Nile virus infection in rodents. Antivir. Res. 80 (2008), 377–379 https://doi.org/10.1016/j.antiviral.2008.07.009.
    • (2008) Antivir. Res. , vol.80 , pp. 377-379
    • Morrey, J.D.1    Taro, B.S.2    Siddharthan, V.3    Wang, H.4    Smee, D.F.5    Christensen, A.J.6    Furuta, Y.7
  • 46
    • 84884693953 scopus 로고    scopus 로고
    • Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)
    • Naesens, L., Guddat, L.W., Keough, D.T., van Kuilenburg, A.B.P., Meijer, J., Vande Voorde, J., Balzarini, J., Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir). Mol. Pharmacol. 84 (2013), 615–629 https://doi.org/10.1124/mol.113.087247.
    • (2013) Mol. Pharmacol. , vol.84 , pp. 615-629
    • Naesens, L.1    Guddat, L.W.2    Keough, D.T.3    van Kuilenburg, A.B.P.4    Meijer, J.5    Vande Voorde, J.6    Balzarini, J.7
  • 47
    • 84924630804 scopus 로고    scopus 로고
    • Favipiravir: a new medication for the Ebola virus disease pandemic
    • Nagata, T., Lefor, A.K., Hasegawa, M., Ishii, M., Favipiravir: a new medication for the Ebola virus disease pandemic. Disaster Med. Public Health Prep. 9 (2015), 79–81 https://doi.org/10.1017/dmp.2014.151.
    • (2015) Disaster Med. Public Health Prep. , vol.9 , pp. 79-81
    • Nagata, T.1    Lefor, A.K.2    Hasegawa, M.3    Ishii, M.4
  • 49
    • 84896129506 scopus 로고    scopus 로고
    • Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model
    • Oestereich, L., Lüdtke, A., Wurr, S., Rieger, T., Muñoz-Fontela, C., Günther, S., Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model. Antivir. Res. 105 (2014), 17–21 https://doi.org/10.1016/j.antiviral.2014.02.014.
    • (2014) Antivir. Res. , vol.105 , pp. 17-21
    • Oestereich, L.1    Lüdtke, A.2    Wurr, S.3    Rieger, T.4    Muñoz-Fontela, C.5    Günther, S.6
  • 55
    • 84905371055 scopus 로고    scopus 로고
    • The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon
    • Rocha-Pereira, J., Nascimento, M.S.J., Ma, Q., Hilgenfeld, R., Neyts, J., Jochmansb, D., The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon. Antimicrob. Agents Chemother. 58 (2014), 4675–4681 https://doi.org/10.1128/AAC.02546-13.
    • (2014) Antimicrob. Agents Chemother. , vol.58 , pp. 4675-4681
    • Rocha-Pereira, J.1    Nascimento, M.S.J.2    Ma, Q.3    Hilgenfeld, R.4    Neyts, J.5    Jochmansb, D.6
  • 56
    • 84960172384 scopus 로고    scopus 로고
    • Treatment with a nucleoside polymerase inhibitor reduces shedding of murine norovirus in stool to undetectable levels without emergence of drug-resistant variants
    • Rocha-Pereira, J., Van Dycke, J., Neyts, J., Treatment with a nucleoside polymerase inhibitor reduces shedding of murine norovirus in stool to undetectable levels without emergence of drug-resistant variants. Antimicrob. Agents Chemother. 60 (2016), 1907–1911 https://doi.org/10.1128/AAC.02198-15.
    • (2016) Antimicrob. Agents Chemother. , vol.60 , pp. 1907-1911
    • Rocha-Pereira, J.1    Van Dycke, J.2    Neyts, J.3
  • 57
    • 84884268745 scopus 로고    scopus 로고
    • Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome
    • Safronetz, D., Falzarano, D., Scott, D.P., Furuta, Y., Feldmann, H., Gowen, B.B., Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome. Antimicrob. Agents Chemother. 57 (2013), 4673–4680 https://doi.org/10.1128/AAC.00886-13.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 4673-4680
    • Safronetz, D.1    Falzarano, D.2    Scott, D.P.3    Furuta, Y.4    Feldmann, H.5    Gowen, B.B.6
  • 61
    • 84894190196 scopus 로고    scopus 로고
    • Favipiravir (T-705) protects against peracute Rift Valley fever virus infection and reduces delayed-onset neurologic disease observed with ribavirin treatment
    • Scharton, D., Bailey, K.W., Vest, Z., Westover, J.B., Kumaki, Y., Van Wettere, A., Furuta, Y., Gowen, B.B., Favipiravir (T-705) protects against peracute Rift Valley fever virus infection and reduces delayed-onset neurologic disease observed with ribavirin treatment. Antivir. Res. 104 (2014), 84–92 https://doi.org/10.1016/j.antiviral.2014.01.016.
    • (2014) Antivir. Res. , vol.104 , pp. 84-92
    • Scharton, D.1    Bailey, K.W.2    Vest, Z.3    Westover, J.B.4    Kumaki, Y.5    Van Wettere, A.6    Furuta, Y.7    Gowen, B.B.8
  • 63
    • 84896692632 scopus 로고    scopus 로고
    • Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model
    • Smither, S.J., Eastaugh, L.S., Steward, J.A., Nelson, M., Lenk, R.P., Lever, M.S., Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model. Antivir. Res. 104 (2014), 153–155 https://doi.org/10.1016/j.antiviral.2014.01.012.
    • (2014) Antivir. Res. , vol.104 , pp. 153-155
    • Smither, S.J.1    Eastaugh, L.S.2    Steward, J.A.3    Nelson, M.4    Lenk, R.P.5    Lever, M.S.6
  • 65
    • 84975886177 scopus 로고    scopus 로고
    • Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir
    • Takashita, E., Ejima, M., Ogawa, R., Fujisaki, S., Neumann, G., Furuta, Y., Kawaoka, Y., Tashiro, M., Odagiri, T., Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir. Antivir. Res. 132 (2016), 170–177 https://doi.org/10.1016/j.antiviral.2016.06.007.
    • (2016) Antivir. Res. , vol.132 , pp. 170-177
    • Takashita, E.1    Ejima, M.2    Ogawa, R.3    Fujisaki, S.4    Neumann, G.5    Furuta, Y.6    Kawaoka, Y.7    Tashiro, M.8    Odagiri, T.9
  • 67
    • 85018731373 scopus 로고    scopus 로고
    • Antiviral activity of favipiravir (T-705) against mammalian and avian bornaviruses
    • Tokunaga, T., Yamamoto, Y., Sakai, M., Tomonaga, K., Honda, T., Antiviral activity of favipiravir (T-705) against mammalian and avian bornaviruses. Antivir. Res. 143 (2017), 237–245 https://doi.org/10.1016/j.antiviral.2017.04.018.
    • (2017) Antivir. Res. , vol.143 , pp. 237-245
    • Tokunaga, T.1    Yamamoto, Y.2    Sakai, M.3    Tomonaga, K.4    Honda, T.5
  • 68
    • 85044470951 scopus 로고    scopus 로고
    • Successful design of ribonucleoside Di- and triphosphate prodrugs to improve the anti-influenza virus activity of T-705 and its analogue T-1105
    • Elsevier Atlanta
    • Vanderlinden, E., Huchting, J., Meier, C., Naesens, L., Successful design of ribonucleoside Di- and triphosphate prodrugs to improve the anti-influenza virus activity of T-705 and its analogue T-1105. International Conference on Antiviral Research, 2017, Elsevier, Atlanta.
    • (2017) International Conference on Antiviral Research
    • Vanderlinden, E.1    Huchting, J.2    Meier, C.3    Naesens, L.4
  • 71
    • 84983535187 scopus 로고    scopus 로고
    • In vitro assessment of combinations of enterovirus inhibitors against enterovirus 71
    • Wang, Y., Li, G., Yuan, S., Gao, Q., Lan, K., Altmeyer, R., Zou, G., In vitro assessment of combinations of enterovirus inhibitors against enterovirus 71. Antimicrob. Agents Chemother. 60 (2016), 5357–5367 https://doi.org/10.1128/AAC.01073-16.
    • (2016) Antimicrob. Agents Chemother. , vol.60 , pp. 5357-5367
    • Wang, Y.1    Li, G.2    Yuan, S.3    Gao, Q.4    Lan, K.5    Altmeyer, R.6    Zou, G.7
  • 72
    • 85031277646 scopus 로고    scopus 로고
    • Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus
    • Welch, S.R., Scholte, F.E.M., Flint, M., Chatterjee, P., Nichol, S.T., Bergeron, É., Spiropoulou, C.F., Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antivir. Res. 147 (2017), 91–99 https://doi.org/10.1016/j.antiviral.2017.10.008.
    • (2017) Antivir. Res. , vol.147 , pp. 91-99
    • Welch, S.R.1    Scholte, F.E.M.2    Flint, M.3    Chatterjee, P.4    Nichol, S.T.5    Bergeron, É.6    Spiropoulou, C.F.7
  • 74
    • 84965161020 scopus 로고    scopus 로고
    • Efficacy of favipiravir (T-705) in rabies postexposure prophylaxis
    • Yamada, K., Noguchi, K., Komeno, T., Furuta, Y., Nishizono, A., Efficacy of favipiravir (T-705) in rabies postexposure prophylaxis. J. Infect. Dis. 213 (2016), 1253–1261 https://doi.org/10.1093/infdis/jiv586.
    • (2016) J. Infect. Dis. , vol.213 , pp. 1253-1261
    • Yamada, K.1    Noguchi, K.2    Komeno, T.3    Furuta, Y.4    Nishizono, A.5
  • 75
    • 85018801820 scopus 로고    scopus 로고
    • Recent progress on the treatment of Ebola virus disease with Favipiravir and other related strategies
    • Zhang, T., Zhai, M., Ji, J., Zhang, J., Tian, Y., Liu, X., Recent progress on the treatment of Ebola virus disease with Favipiravir and other related strategies. Bioorg. Med. Chem. Lett. 27 (2017), 2364–2368 https://doi.org/10.1016/j.bmcl.2017.04.028.
    • (2017) Bioorg. Med. Chem. Lett. , vol.27 , pp. 2364-2368
    • Zhang, T.1    Zhai, M.2    Ji, J.3    Zhang, J.4    Tian, Y.5    Liu, X.6
  • 76
    • 84971658665 scopus 로고    scopus 로고
    • The viral polymerase inhibitor 7-deaza-2’-C-methyladenosine is a potent inhibitor of in vitro zika virus replication and delays disease progression in a robust mouse infection model
    • Zmurko, J., Marques, R.E., Schols, D., Verbeken, E., Kaptein, S.J.F., Neyts, J., The viral polymerase inhibitor 7-deaza-2’-C-methyladenosine is a potent inhibitor of in vitro zika virus replication and delays disease progression in a robust mouse infection model. PLoS Negl. Trop. Dis., 2016 https://doi.org/10.1371/journal.pntd.0004695.
    • (2016) PLoS Negl. Trop. Dis.
    • Zmurko, J.1    Marques, R.E.2    Schols, D.3    Verbeken, E.4    Kaptein, S.J.F.5    Neyts, J.6


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