Making sense of a haemolysis monitoring and reporting system: A nationwide longitudinal multimethod study of 68 Australian laboratory participant organisations

Clinical Chemistry and Laboratory Medicine

Volumn 56, Issue 4, 2018, Pages 565-573

  Li, Ling ^a   Vecellio, Elia ^a,b   Gay, Stephanie ^c   Lake, Rebecca ^a   MacKay, Mark ^c   Burnett, Leslie ^d   Chesher, Douglas ^e,f   Braye, Stephen ^e,g   Badrick, Tony ^c   Westbrook, Johanna I ^a   Georgiou, Andrew ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b New South Wales Government   (Australia)

^c Royal College of Pathologists of Australasia Quality Assurance Programs in Biosecurity   (Australia)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

^f ROYAL NORTH SHORE HOSPITAL   (Australia)

^g NSW Health Pathology   (Australia)

Author keywords

haemolysis; laboratory medicine; laboratory monitoring and management systems; patient safety; preanalytical errors; quality control; specimen rejection

Indexed keywords

ARTICLE; BIOLOGICAL MONITORING; CLINICAL ASSESSMENT; CLINICAL LABORATORY; COHORT ANALYSIS; DATA BASE; HEALTH CARE ORGANIZATION; HEALTH SURVEY; HEMOLYSIS; HUMAN; HUMAN TISSUE; KEY INCIDENT MONITORING AND MANAGEMENT SYSTEM; LABORATORY INFORMATION SYSTEM; LABORATORY TEST; PATIENT MONITORING; PREVALENCE; PRIORITY JOURNAL; QUALITY CONTROL; RETROSPECTIVE STUDY; AUSTRALIA; BLOOD SAMPLING; LONGITUDINAL STUDY;

AUSTRALIA; BLOOD SPECIMEN COLLECTION; CLINICAL LABORATORY INFORMATION SYSTEMS; COHORT STUDIES; HEMOLYSIS; HUMANS; LONGITUDINAL STUDIES; RETROSPECTIVE STUDIES;

EID: 85043708842     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2017-0056     Document Type: Article

References (55)

1. Franco R. The measurement and importance of red cell survival. Am J Hematol 2009;84:109-14.
2. Lippi G, Blanckaert N, Bonini P, Green S, Kitchen S, Palicka V, et al. Haemolysis: An overview of the leading cause of unsuitable specimens in clinical laboratories. Clin Chem Lab Med 2008;46:764-72.
3. Simundic AM, Topic E, Nikolac N, Lippi G. Hemolysis detection and management of hemolyzed specimens. Biochem Med 2010;20:154-9.
4. Bonini P, Plebani M, Ceriotti F, Rubboli F. Errors in laboratory medicine. Clin Chem 2002;48:691-8.
5. Lippi G, Guidi G, Mattiuzzi C, Plebani M. Preanalytical variability: The dark side of the moon in laboratory testing. Clin Chem Lab Med 2006;44:358-65.
6. Lippi G. Practices for identifying and rejecting hemolyzed specimens in Europe. Arch Pathol Lab Med 2016;140:622.
7. Specimencare.com. Global Preanalytical Scientific Committee. at: http://www.specimencare.com. Accessed: 24 Mar 2017.
8. Howanitz P, Lehman C, Jones B, Meier F, Horowitz G. Practices for identifying and rejecting hemolyzed specimens are highly variable in clinical laboratories. Arch Pathol Lab Med 2015;139:1014-9.
9. Dugan L, Leech L, Speroni KG, Corriher J. Factors affecting hemolysis rates in blood samples drawn from newly placed IV sites in the emergency department. J Emerg Nurs 2005;31:338-45.
10. Streitberg G, Angel L, Sikaris K. Laboratory information systems in clinical biochemistry in Australia. Aust J Med Sci 2014;35:2-8.
11. Fifield L. The need for usability in electronic lab ordering. MLO Med Lab Obs 2013;45:14.
12. Georgiou A, Vecellio E, Toouli G, Eigenstetter A, Li L, Wilson R, et al. Monitoring the impact of the electronic medical record on the quality of laboratory test ordering practices. In: Grain H, Schaper LK, editors. Health informatics: Digital health service delivery-the future is now! 1st ed. Amsterdam: IOS Press, 2013:33-8.
13. Park S, Pantanowitz L, Parwani A. Quality assurance in anatomic pathology. Diagn Histopathol 2013;19:438-46.
14. Sepulveda J, Young D. The ideal laboratory information system. Arch Pathol Lab Med 2013;137:1129-40.
15. Plebani M, Sciacovelli L, Aita A, Pelloso M, Chiozza ML. Performance criteria and quality indicators for the pre-Analytical phase. Clin Chem Lab Med 2015;53:943-8.
16. McCaughey E, Vecellio E, Lake R, Li L, Gay S, Mackay M, et al. Current methods of haemolysis detection and reporting as a source of risk to patient safety: A narrative review. Clin Biochem Rev 2016;37:143-51.
17. Atay A, Demir L, Cuhadar S, Saglam G, Unal H, Aksun S, et al. Clinical biochemistry laboratory rejection rates due to various types of preanalytical errors. Biochem Med 2014;24:376-82.
18. Carraro P, Zago T, Plebani M. Exploring the initial steps of the testing process: Frequency and nature of pre-preanalytic errors. Clin Chem 2012;58:638-42.
19. Chawla R, Goswami B, Tayal D, Mallika V. Identification of the types of preanalytical errors in the clinical chemistry laboratory: 1-year study at G.B. Pant Hospital. Lab Med 2010;41:89-92.
20. Dietrich H. One poke or two: Can intravenous catheters provide an acceptable blood sample? A data set presentation, review of previous data sets, and discussion. J Emerg Nurs 2014;40:575-8.
21. Goswami B, Singh B, Chawla R, Mallika V. Evalutation of errors in a clinical laboratory: A one-year experience. Clin Chem Lab Med 2010;48:63-6.
22. Grecu DS, Vlad DC, Dumitrascu V. Quality indicators in the preanalytical phase of testing in a stat laboratory. Lab Med 2014;45:74-81.
23. Lippi G, Bassi A, Brocco G, Montagnana M, Salvagno GL, Guidi GC. Preanalytic error tracking in a laboratory medicine department: Results of a 1-year experience. Clin Chem 2006;52:1442-3.
24. Berger-Achituv S, Budde-Schwartzman B, Ellis MH, Shenkman Z, Erez I. Blood sampling through peripheral venous catheters is reliable for selected basic analytes in children. Pediatrics 2010;126:e179-86.
25. Carraro P, Servidio G, Plebani M. Hemolyzed specimens: A reason for rejection or a clinical challenge? Clin Chem 2000;46:306-7.
26. Cox SR, Dages JH, Jarjoura D, Hazelett S. Blood samples drawn from IV catheters have less hemolysis when 5-mL (vs. 10-mL) collection tubes are used. J Emerg Nurs 2004;30:529-33.
27. Fernandez P, Llopis MA, Perich C, Alsina MJ, Alvarez V, Biosca C, et al. Harmonization in hemolysis detection and prevention. A working group of the Catalonian Health Institute (ICS) experience. Clin Chem Lab Med 2014;52:1557-68.
28. Romero A, Cobos A, López-León A, Ortega G, Munõz M. Preanalytical mistakes in samples from primary care patients. Clin Chem Lab Med 2009;47:1549-52.
29. Salvagno GL, Lippi G, Bassi A, Poli G, Guidi GC. Prevalence and type of pre-Analytical problems for inpatients samples in coagulation laboratory. J Eval Clin Pract 2008;14:351-3.
30. Berg JE, Ahee P, Berg JD. Variation in phlebotomy techniques in emergency medicine and the incidence of haemolysed samples. Ann Clin Biochem 2011;48:562-5.
31. Bölenius K, Söderberg J, Hultdin J, Lindkvist M, Brulin C, Grankvist K. Minor improvement of venous blood specimen collection practices in primary health care after a large-scale educational intervention. Clin Chem Lab Med 2013;51:303-10.
32. Brunel V, Larson T, Peschanski N, Cauliez B. Evaluation of haemolysis in emergency department samples requesting high sensitivity troponin T measurement. Ann Clin Biochem 2012;49:509-10.
33. Burns ER, Yoshikawa N. Hemolysis in serum samples drawn by emergency department personnel versus laboratory phlebotomists. Lab Med 2002;33:378-80.
34. Davidson DF. A survey of some pre-Analytical errors identified from the biochemistry department of a Scottish hospital. Scot Med J 2014;59:91-4.
35. Dwyer DG, Fry M, Somerville A, Holdgate A. Randomized, single blinded control trial comparing haemolysis rate between two cannula aspiration techniques. Emerg Med Australas 2006;18:484-8.
36. Ellis G. An episode of increased hemolysis due to a defective pneumatic air tube delivery system. Clin Biochem 2009;42:1265-9.
37. Fang L, Fang S-H, Chung Y-H, Chien S-T. Collecting factors related to the haemolysis of blood specimens. J Clin Nurs 2008;17:2343-51.
38. Giménez-Marin A, Rivas-Ruiz F, del Mar Pérez-Hidalgo M, Molina-Mendoza P. Pre-Analytical errors management in the clinical laboratory: A five-year study. Biochem Med 2014;24:248-57.
39. Kara H, Bayir A, Ak A, Degirmenci S, Akinci M, Agacayak A, et al. Hemolysis associated with pneumatic tube system transport for blood samples. Pak J Med Sci 2014;30:50-8.
40. Lowe G, Stike R, Pollack M, Bosley J, O'Brien P, Hake A, et al. Nursing blood specimen collection techniques and hemolysis rates in an emergency department: Analysis of venipuncture versus intravenous catheter collection techniques. J Emerg Nurs 2008;34:26-32.
41. Munnix IC, Schellart M, Gorissen C, Kleinveld HA. Factors reducing hemolysis rates in blood samples from the emergency department. Clin Chem Lab Med 2010;49:157-8.
42. Saleem S, Mani V, Chadwick MA, Creanor S, Ayling RM. A prospective study of causes of haemolysis during venepuncture: Tourniquet time should be kept to a minimum. Ann Clin Biochem 2009;46:244-6.
43. Söderberg J, Jonsson PA, Wallin O, Grankvist K, Hultdin J. Haemolysis index-An estimate of preanalytical quality in primary health care. Clin Chem Lab Med 2009;47:940-4.
44. Sodi R, Darn SM, Davison AS, Stott A, Shenkin A. Mechanism of interference by haemolysis in the cardiac troponin T immunoassay. Ann Clin Biochem 2006;43:49-56.
45. Straszewski SM, Sanchez L, McGillicuddy D, Boyd K, DuFresne J, Joyce N, et al. Use of separate venipunctures for IV access and laboratory studies decreases hemolysis rates. Intern Emerg Med 2011;6:357-9.
46. Tanabe P, Kyriacou DN, Garland F. Factors affecting the risk of blood bank specimen hemolysis. Acad Emerg Med 2003;10:897-900.
47. Wollowitz A, Bijur PE, Esses D, Gallagher EJ. Use of butterfly needles to draw blood is independently associated with marked reduction in hemolysis compared to intravenous catheter. Acad Emerg Med 2013;20:1151-5.
48. Lippi G, Bonelli P, Cervellin G. Prevalence and cost of hemolyzed samples in a large urban emergency department. Int J Lab Hematol 2014;36:e24-6.
49. Grant MS. The effect of blood drawing techniques and equipment on the hemolysis of ED laboratory blood samples. J Emerg Nurs 2003;29:116-21.
50. Lippi G, Avanzini P, Aloe R, Cervellin G. Blood collection from intravenous lines: Is one drawing site better than others? Lab Med 2014;45:172-5.
51. Shah KG, Idrovo JP, Nicastro J, McMullen HF, Molmenti EP, Coppa G. A retrospective analysis of the incidence of hemolysis in type and screen specimens from trauma patients. Int Angiol 2009;18:182-3.
52. Stauss M, Sherman B, Pugh L, Parone D, Looby-Rodriguez K, Bell A, et al. Hemolysis of coagulation specimens: A comparative study of intravenous draw methods. J Emerg Nurs 2012;38:15-21.
53. Badrick T, Barden H, Callen S, Dimeski G, Gay S, Graham P, et al. Consensus statement for the management and reporting of haemolysed specimens. Clin Biochem Rev 2016;37:140-2.
54. Plebani M, Sciacovelli L, Aita A. Quality indicators for the total testing process. Clin Lab Med 2017;37:187-205.
55. Sciacovelli L, Lippi G, Sumarac Z, West J, Garcia Del Pino Castro I, Furtado Vieira K, et al. Quality indicators in laboratory medicine: The status of the progress of IFCC Working Group "Laboratory Errors and Patient Safety" project. Clin Chem Lab Med 2017;55:348-57.