What's in a name: are cultured red blood cells ‘natural’?

Sociology of Health and Illness

Volumn 40, Issue 4, 2018, Pages 687-701

  King, Emma ^a   Lyall, Catherine ^b  

^a UNIVERSITY OF STIRLING   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

blood; ethnography; identity; patient and public engagement; stem cell research

Indexed keywords

ADULT; ARTICLE; CLASSIFICATION; DRAWING; ERYTHROCYTE CULTURE; ETHNOGRAPHY; EXPECTATION; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IDENTITY; INFORMATION PROCESSING; INTERVIEW; MALE; STEM CELL RESEARCH; BLOOD DONOR; BLOOD TRANSFUSION; CELL CULTURE; CULTURAL ANTHROPOLOGY; ERYTHROCYTE; ETHICS; PROCEDURES; PUBLIC OPINION;

ANTHROPOLOGY, CULTURAL; BLOOD DONORS; BLOOD TRANSFUSION; CELLS, CULTURED; ERYTHROCYTES; FOCUS GROUPS; HUMANS; INTERVIEWS AS TOPIC; PUBLIC OPINION; STEM CELL RESEARCH;

EID: 85042739182     PISSN: 01419889     EISSN: 14679566     Source Type: Journal    
DOI: 10.1111/1467-9566.12717     Document Type: Article

References (52)

1. Barnes, B. (1983) On the conventional character of knowledge and cognition. In Knorr-Cetina, K.D. and M. Mulkay (eds) Science observed: Perspectives on the social study of science. London: Sage.
2. Barnes, B., Bloor, D. and Henry, J. (1996) Scientific knowledge: A sociological analysis. London: Athlone.
3. Bates, S.R., Faulkner, W., Parry, S. and Cunningham-Burley, S. (2010) ‘How do we know it's not been done yet?!’ Trust, trust building and regulation in stem cell research, Science and Public Policy, 37, 9, 703–18.
4. Bessos, H., Fraser, R. and Seghatchian, J. (2008) Scotblood 2007, Tackling local and global issues in transfusion medicine: Donor recruitment, effective use of blood, stem cell plasticity, and vCJD, Transfusion and Apheresis Science, 38, 1, 77–83.
5. Bryman, A. (2012) Social research methods. Oxford: Oxford University Press.
6. Carsten, J. (2011) Substance and relationality: Blood in contexts, Annual Review Anthropology, 40, 19–35.
7. Charmaz, K. (2014) Constructing grounded theory. Los Angeles: Sage.
8. Cohn, C.S. and Cushing, M.M. (2009) Oxygen therapeutics: Perfluorocarbons and blood substitute safety, Critical Care Clinics, 25, 399–414.
9. Douglas, M. (1966) Purity and danger. London: Routledge.
10. Dragojlovic, N. and Einsiedel, E. (2013) Framing synthetic biology: Evolutionary distance, conceptions of nature, and the nnnaturalness objection, Science Communication, 35, 5, 547–71.
11. Ferguson, E., Prowse, C., Townsend, E., Spence, A., et al. (2008) Acceptability of blood and blood substitutes, Journal of Internal Medicine, 263, 3, 244–55.
12. Fleming, P., Ferguson, E., Townsend, E. and Lowe, K.C. (2007) Perceptions in transfusion medicine: A pilot field study on risk and ethics for blood and blood substitutes, Artificial Cells, Blood Substitutes, And Immobilization Biotechnology, 35, 2, 149–56.
13. Fox Keller, E. (2008) Nature and the natural, BioSocieties, 3, 2, 117–24.
14. Hauskeller, C. (2005) Science in touch: Functions of biomedical terminology, Biology and Philosophy, 20, 8, 15–35.
15. Hansen, A. (2006) Tampering with nature: ‘Nature’ and the ‘natural’ in media coverage of genetics and biotechnology, Media, Culture & Society, 28, 6, 811–34.
16. Harvey, D. (1996) Justice, nature and the geography of difference. London: Blackwell.
17. Hough, A. (2010) Synthetic blood breakthrough after scientists ‘produce red cells from IVF embryos’, Telegraph, 16 August. Available at http://www.telegraph.co.uk/news/health/news/7947628/Synthetic-blood-breakthrough-after-scientists-produce-red-cells-from-IVF-embryos.html (Last accessed 9 March 2017).
18. Jasanoff, S. (2005) In the democracies of DNA: Ontological uncertainty and political order in three states, New Genetics and Society, 24, 2, 139–55.
19. Jönsson, E. (2016) Benevolent technotopias and hitherto unimaginable meats: Tracing the promises of in vitro meat, Social Studies of Science, 46, 5, 725–48.
20. King, E. (2013) Blood, sweat and tears: A case study of the development of cultured red blood cells for transfusion. PhD thesis, University of Edinburgh.
21. King, E. (2015) Biodiversity and perceptions of risk: Reactions to the use of a single donor for stem-cell-derived red blood cell transfusions, Journal of Medical Law and Ethics, 3, 3, 151–63.
22. King, E. (2017) Who is my donor? in Pavone, V. and Goven, J. (eds) Bioeconomies: Life, technology, and capital in the 21st century. Cham: Palgrave Macmillan.
23. King, E. and Lyall, C. (2015) Eliciting the views of the wider public regarding the potential introduction of cultured red blood cells for transfusion. Confidential project report Workstream 7 Industrially generated red blood cells for transfusion (February 2015).
24. Kronberger, N. (2015) Of worlds and objects: scientific knowledge and its publics. In Sammut, G., Andreouli, E., Gaskell, G. and Valsiner, J. (eds) Cambridge handbook of social representations. Cambridge: Cambridge University Press.
25. Li, G., Sun, T.W., Luo, G. and Zhang, C. (2017) Efficacy of antifibrinolytic agents on surgical bleeding and transfusion requirements in spine surgery: A meta-analysis, European Spine Journal, 26, 1, 140–54.
26. Lowe, K.C., Farrell, K., Ferguson, E.M. and James, V. (2001) Current perceived risks of transfusion in the UK and relevance to the future acceptance of blood substitutes, Artificial Cells, Blood Substitutes, and Immobilization Biotechnology, 29, 3, 179–89.
27. Lyall, C. and King, E. (2016) Using qualitative research in biomedical innovation: The case of cultured red blood cells for transfusion, BMC Research Notes, 9, 267, 1–9.
28. MacRae, F. (2011) Synthetic blood created by British scientists could be used in transfusions in just two years, Daily Mail, 28 October. Available at:http://www.dailymail.co.uk/health/article-2053829/Artificial-blood-stem-cells-used-transfusions-just-years.html (Last accessed 9 March 2017).
29. Marcu, A., Gaspar, R., Rutsaert, P., Seibt, B., et al. (2015) Analogies, metaphors, and wondering about the future: Lay sense-making around synthetic meat, Public Understanding of Science, 24, 5, 547–62.
30. Marcus, G.E. (1995) Ethnography in/of the world system: The emergence of multi-sited ethnography, Annual Review of Anthropology, 24, 95–117.
31. Marks, N.J. (2010) Defining stem cells? Scientists and their classifications of nature, The Sociological Review, 58, Suppl 1, S32–50.
32. McRoberts, R.J., Beard, D. and Walsh, T.S. (2007) A study of blood product use in patients with major trauma in Scotland: Analysis of a major trauma database, Emergency Medicine Journal, 24, 5, 325–9.
33. Mittra, J., Tait, J., Mastroeni, M., Turner, M., et al. (2015) Identifying viable regulatory and innovation pathways for regenerative medicine: a case study of cultured red blood cells, New Biotechnology, 32, 1, 180–90.
34. Moscovici, S. (1961/ 2008) Psychoanalysis: Its image and its public. Edited by G. Duveen, trans. D. Macey. Cambridge: Polity Press.
35. Mountford, J.C. (2008) Human embryonic stem cells: Origins, characteristics and potential for regenerative therapy, Transfusion Medicine, 18, 1, 1–12.
36. Mountford, J.C. and Turner, M. (2011) In vitro production of red blood cells, Transfusion and Apheresis Science, 45, 1, 85–9.
37. Nuffield Council on Bioethics (2015) Ideas about naturalness in public and political debates about science, technology and medicine. Analysis Paper, November 2015, Nuffield Council on Bioethics, London.
38. Parry, S. and Dupré, J. (2010) Introducing nature after the genome, The Sociological Review, 58, s1, 3–16.
39. Siegrist, M. (2000) The influence of trust and perceptions of risks and benefits on the acceptance of gene technology, Risk Analysis, 20, 2, 195–204.
40. Starr, D. (1999) Blood: An epic history of medicine and commerce. London: Little, Brown and Company.
41. Stephens, N. (2010) In vitro meat: Zombies on the menu? Scripted, 7, 2, 394–401.
42. Stephens, N., King, E. and Lyall, C. (In press) Blood, meat, and upscaling tissue engineering: Promises, anticipated markets, and performativity in the biomedical and agri-food sectors’, Biosocieties.
43. Strauss, A.L. and Corbin, J. (1994) Grounded theory methodology. In Denzin, N.K. and Lincoln, Y.S. (eds) Handbook of qualitative research. London: Sage.
44. Swierstra, T., van Est, R. and Boenink, M. (2009) Taking care of the symbolic order, How converging technologies challenge our concepts, Nanoethics, 3, 3, 269–80.
45. Thorne, S. (2000) Data analysis in qualitative research, Evidence Based Nursing, 3, 3, 68–70.
46. Titmuss, R.M. (1970) The gift relationship: From human blood to social policy. London: LSE Books.
47. Trakarnsanga, K., Griffiths, R.E., Wilson, M.C., Blair, A., et al. (2017) An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells, Nature Communications, 8, 14750, 1–7, https://doi.org/10.1038/ncomms14750.
48. Voelklein, C. and Howarth, C. (2005) A review of controversies about social representations theory: A British debate, Culture & Psychology, 11, 4, 431–54.
49. Vogelstein, B., Alberts, B. and Shine, K. (2002) Please don't call it cloning!, Science, 295, 5558, 1237.
50. Waldby, C. (2002) Stem cells, tissue cultures and the production of biovalue, Health, 6, 3, 305–23.
51. Weltert, L., Nardella, S., Rondinelli, M.B., Pierelli, L., et al. (2013) Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intra-and postoperative blood salvage strategy: Results of a randomized comparison, Transfusion, 53, 4, 790–7.
52. Wright Mills, C. (1940) Situated actions and vocabularies of motive, American Sociological Review, 5, 6, 904–13.