CSF1R inhibition prevents radiation pulmonary fibrosis by depletion of interstitial macrophages

European Respiratory Journal

Volumn 51, Issue 3, 2018, Pages

  Meziani, Lydia ^a,b   Mondini, Michele ^a,b   Petit, Benoît ^c   Boissonnas, Alexandre ^d,e   De Montpreville, Vincent Thomas ^b,f   Mercier, Olaf ^b,f   Vozenin, Marie Catherine ^c   Deutsch, Eric ^a,b  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b SIRIC SOCRATE   (United Kingdom)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^d INSERM   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; COLONY STIMULATING FACTOR RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; CLODRONIC ACID; CSF1R PROTEIN, HUMAN; CSF1R PROTEIN, MOUSE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; LIPOSOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG BIOPSY; LUNG FIBROSIS; LUNG LAVAGE; MACROPHAGE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION INDUCED LUNG FIBROSIS; RADIATION INJURY; TH1 CELL; TH2 CELL; THORAX CANCER; TISSUE INFILTRATING MACROPHAGE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DOWN REGULATION; GENETICS; LUNG; LUNG INJURY; METABOLISM; RADIATION PNEUMONIA;

ANIMALS; CLODRONIC ACID; CYTOKINES; DOWN-REGULATION; FEMALE; HUMANS; LIPOSOMES; LUNG; LUNG INJURY; MACROPHAGES; MICE; MICE, INBRED C57BL; PULMONARY FIBROSIS; RADIATION PNEUMONITIS; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; UP-REGULATION;

EID: 85042641450     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.02120-2017     Document Type: Article

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