Investigation of insulin resistance in the popularly used four rat models of type-2 diabetes

Biomedicine and Pharmacotherapy

Volumn 101, Issue , 2018, Pages 155-161

  Chao, Pin Chun ^a   Li, Yingxiao ^b,c   Chang, Chin Hong ^c   Shieh, Ja Ping ^c   Cheng, Juei Tang ^c,d   Cheng, Kai Chun ^b  

^a SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Euglycemic clamp; HOMA IR; Insulin resistance; Rat models; T2DM

Indexed keywords

FRUCTOSE; HUMAN INSULIN; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; NICOTINAMIDE; PROTEIN KINASE B; STREPTOZOCIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; HYPERGLYCEMIA; INJECTION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SIGNALING; LIPID DIET; LOW DRUG DOSE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RAT MODEL; SINGLE DRUG DOSE; SOLEUS MUSCLE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ADVERSE EVENT; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; FAT INTAKE; GLUCOSE BLOOD LEVEL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DIETARY FATS; DISEASE MODELS, ANIMAL; FRUCTOSE; INSULIN RESISTANCE; MALE; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN;

EID: 85042434388     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2018.02.084     Document Type: Article

References (53)

1. Dejkhamron, P., Menon, R.K., Sperling, M.A., Childhood diabetes mellitus: recent advances & future prospects. Indian J. Med. Res. 125:3 (2007), 231–250.
2. N.C.D.R.F. Collaboration, Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet 387:10027 (2016), 1513–1530.
3. Gagliardi, L., Wittert, G., Management of obesity in patients with type 2 diabetes mellitus. Curr. Diabetes Rev. 3:2 (2007), 95–101.
4. Kalofoutis, C., Piperi, C., Kalofoutis, A., Harris, F., Phoenix, D., Singh, J., Type II diabetes mellitus and cardiovascular risk factors: current therapeutic approaches. Exp. Clin. Cardiol. 12:1 (2007), 17–28.
5. Saini, V., Molecular mechanisms of insulin resistance in type 2 diabetes mellitus. World J. Diabetes 1:3 (2010), 68–75.
6. Peth, J.A., Kinnick, T.R., Youngblood, E.B., Tritschler, H.J., Henriksen, E.J., Effects of a unique conjugate of alpha-lipoic acid and gamma-linolenic acid on insulin action in obese Zucker rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278:2 (2000), R453–R459.
7. Soumaya, K., Molecular mechanisms of insulin resistance in diabetes. Adv. Exp. Med. Biol. 771 (2012), 240–251.
8. Heydemann, A., An overview of murine high fat diet as a model for type 2 diabetes mellitus. J. Diabetes Res., 2016, 2016, 2902351.
9. Runtuwene, J., Cheng, K.C., Asakawa, A., Amitani, H., Amitani, M., Morinaga, A., Takimoto, Y., Kairupan, B.H., Inui, A., Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4. Drug Des. Dev. Ther. 10 (2016), 2193–2202.
10. D'Angelo, G., Elmarakby, A.A., Pollock, D.M., Stepp, D.W., Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension 46:4 (2005), 806–811.
11. Masiello, P., Broca, C., Gross, R., Roye, M., Manteghetti, M., Hillaire-Buys, D., Novelli, M., Ribes, G., Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes 47:2 (1998), 224–229.
12. Ito, M., Kondo, Y., Nakatani, A., Hayashi, K., Naruse, A., Characterization of low dose streptozotocin-induced progressive diabetes in mice. Environ. Toxicol. Pharmacol. 9:3 (2001), 71–78.
13. Okoduwa, S.I., Umar, I.A., James, D.B., Inuwa, H.M., Appropriate insulin level in selecting fortified diet-fed, streptozotocin-treated rat model of type 2 diabetes for anti-diabetic studies. PLoS One, 12(1), 2017, e0170971.
14. Lukic, M.L., Stosic-Grujicic, S., Shahin, A., Effector mechanisms in low-dose streptozotocin-induced diabetes. Dev. Immunol. 6:1–2 (1998), 119–128.
15. Reed, M.J., Meszaros, K., Entes, L.J., Claypool, M.D., Pinkett, J.G., Gadbois, T.M., Reaven, G.M., A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metab. Clin. Exp. 49:11 (2000), 1390–1394.
16. Su, C.H., Liu, I.M., Chung, H.H., Cheng, J.T., Activation of I2-imidazoline receptors by agmatine improved insulin sensitivity through two mechanisms in type-2 diabetic rats. Neurosci. Lett. 457:3 (2009), 125–128.
17. Zhang, M., Lv, X.Y., Li, J., Xu, Z.G., Chen, L., The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp. Diabetes Res., 2008, 2008, 704045.
18. Srinivasan, K., Viswanad, B., Asrat, L., Kaul, C.L., Ramarao, P., Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol. Res. 52:4 (2005), 313–320.
19. Kuo, S.C., Chung, H.H., Huang, C.H., Cheng, J.T., Decrease of hyperglycemia by syringaldehyde in diabetic rats. Horm. Metab. Res. = Hormon- und Stoffwechselforschung = Hormones et metabolisme 46:1 (2014), 8–13.
20. Steele, R., Influences of glucose loading and of injected insulin on hepatic glucose output. Ann. N.Y. Acad. Sci. 82 (1959), 420–430.
21. Chiu, Y.J., Chung, H.H., Yeh, C.H., Cheng, J.T., Lo, S.H., Improvement of insulin resistance by Chlorella in fructose-rich chow-fed rats. Phytother. Res. 25:9 (2011), 1306–1312.
22. Nayak, Y., Hillemane, V., Daroji, V.K., Jayashree, B.S., Unnikrishnan, M.K., Antidiabetic activity of benzopyrone analogues in nicotinamide-streptozotocin induced type 2 diabetes in rats. Sci. World J., 2014, 2014, 854267.
23. Lin, J.D., Chiou, W.K., Chang, H.Y., Liu, F.H., Weng, H.F., Serum uric acid and leptin levels in metabolic syndrome: a quandary over the role of uric acid. Metab. Clin. Exp. 56:6 (2007), 751–756.
24. Paneni, F., Costantino, S., Cosentino, F., Insulin resistance, diabetes, and cardiovascular risk. Curr. Atheroscler. Rep., 16(7), 2014, 419.
25. Hooper, P.L., Balogh, G., Rivas, E., Kavanagh, K., Vigh, L., The importance of the cellular stress response in the pathogenesis and treatment of type 2 diabetes. Cell Stress Chaperones 19:4 (2014), 447–464.
26. Rui, X., Xu, B., Su, J., Pan, C., Zhan, C., Su, B., Li, H., Wang, J., Sheng, H., Qu, S., Differential pattern for regulating insulin secretion, insulin resistance, and lipid metabolism by osteocalcin in male and female T2DM patients. Med. Sci. Monit. Int. Med. J. exp. Clin. Res. 20 (2014), 711–719.
27. Cheng, K.C., Asakawa, A., Li, Y.X., Chung, H.H., Amitani, H., Ueki, T., Cheng, J.T., Inui, A., Silymarin induces insulin resistance through an increase of phosphatase and tensin homolog in Wistar rats. Plos One, 9(1), 2014, e84550.
28. Ko, W.C., Liu, I.M., Chung, H.H., Cheng, J.T., Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats. Neurosci. Lett. 448:1 (2008), 90–93.
29. Yang, G., Li, C.L., Tian, H., Cheng, S.W., Li, Y.J., Cheng, X.L., Fang, F.S., Different establishing conditions of hyperinsulinemic-euglycemic clamp technique among different groups. Zhonghua yi xue za zhi 92:34 (2012), 2410–2414.
30. Furman, B.L., Streptozotocin-induced diabetic models in mice and rats. Curr. Protoc. Pharmacol. 70 (2015), 1–20 5 47.
31. Rahier, J., Guiot, Y., Goebbels, R.M., Sempoux, C., Henquin, J.C., Pancreatic beta-cell mass in European subjects with type 2 diabetes. Diabetes Obes. Metab. 10:Suppl. 4 (2008), 32–42.
32. Rabbani, S.I., Devi, K., Khanam, S., Inhibitory effect of glimepiride on nicotinamide-streptozotocin induced nuclear damages and sperm abnormality in diabetic Wistar rats. Indian J. Exp. Biol. 47:10 (2009), 804–810.
33. Matsumoto, T., Wakabayashi, K., Kobayashi, T., Kamata, K., Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. Can. J. Physiol. Pharmacol. 82:3 (2004), 175–182.
34. Rabbani, S.I., Devi, K., Khanam, S., Role of pioglitazone with metformin or glimepiride on oxidative stress-induced nuclear damage and reproductive toxicity in diabetic rats. Malaysian J. Med. Sci.: MJMS 17:1 (2010), 3–11.
35. Munnich, A., Marie, J., Reach, G., Vaulont, S., Simon, M.P., Kahn, A., In vivo hormonal control of L-type pyruvate kinase gene expression. Effects of glucagon, cyclic AMP, insulin, cortisone, and thyroid hormones on the dietary induction of mRNAs in the liver. J. Biol. Chem. 259:16 (1984), 10228–10231.
36. Yadav, S.P., Vats, V., Ammini, A.C., Grover, J.K., Brassica juncea (Rai) significantly prevented the development of insulin resistance in rats fed fructose-enriched diet. J. Ethnopharmacol. 93:1 (2004), 113–116.
37. Vasiljevic, A., Bursac, B., Djordjevic, A., Milutinovic, D.V., Nikolic, M., Matic, G., Velickovic, N., Hepatic inflammation induced by high-fructose diet is associated with altered 11betaHSD1 expression in the liver of Wistar rats. Eur. J. Nutr. 53:6 (2014), 1393–1402.
38. Crescenzo, R., Bianco, F., Falcone, I., Coppola, P., Liverini, G., Iossa, S., Increased hepatic de novo lipogenesis and mitochondrial efficiency in a model of obesity induced by diets rich in fructose. Eur. J. Nutr. 52:2 (2013), 537–545.
39. Sulis, P.M., Motta, K., Barbosa, A.M., Besen, M.H., da Silva, J.S., Nunes, E.A., Rafacho, A., Impact of fish oil supplementation and interruption of fructose ingestion on glucose and lipid homeostasis of rats drinking different concentrations of fructose. Biomed. Res. Int., 2017, 2017, 4378328.
40. Sah, S.P., Singh, B., Choudhary, S., Kumar, A., Animal models of insulin resistance: a review. Pharmacol. Rep.: PR 68:6 (2016), 1165–1177.
41. Lillioja, S., Mott, D.M., Spraul, M., Ferraro, R., Foley, J.E., Ravussin, E., Knowler, W.C., Bennett, P.H., Bogardus, C., Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N. Engl. J. Med. 329:27 (1993), 1988–1992.
42. Skovso, S., Modeling type 2 diabetes in rats using high fat diet and streptozotocin. J. Diabetes Investig. 5:4 (2014), 349–358.
43. Kumar, M., Sharma, S., Vasudeva, N., In vivo assessment of antihyperglycemic and antioxidant activity from oil of seeds of brassica nigra in streptozotocin induced diabetic rats. Adv. Pharma. Bull. 3:2 (2013), 359–365.
44. Saravanan, R., Pari, L., Succinic acid monoethyl ester prevents oxidative stress in streptozotocin-nicotinamide-induced type2 diabetic rats. J. Basic Clin. Physiol. Pharmacol. 17:2 (2006), 115–132.
45. Dankner, R., Chetrit, A., Shanik, M.H., Raz, I., Roth, J., Basal state hyperinsulinemia in healthy normoglycemic adults heralds dysglycemia after more than two decades of follow up. Diabetes Metab. Res. Rev. 28:7 (2012), 618–624.
46. Ha, T.Y., Kim, Y.S., Kim, C.H., Choi, H.S., Yang, J., Park, S.H., Kim, D.H., Rhee, J.K., Novel GPR119 agonist HD0471042 attenuated type 2 diabetes mellitus. Arch. Pharmacal Res. 37:5 (2014), 671–678.
47. Qiu, N.C., Zhang, Q., Song, X., Liu, M.E., Li, X.K., Shan, C.X., Qiu, M., Impact of the hepatic branch of the vagus and Roux-en-Y gastric bypass on the hypoglycemic effect and glucagon-like peptide-1 in rats with type 2 diabetes mellitus. J. Surg. Res. 191:1 (2014), 123–129.
48. Zhang, S.Y., Sun, X.J., Zheng, J.B., Wang, W., Liu, D., Chen, N.Z., He, S., Huo, X.W., Smith, W., Preserve common limb in duodenal-jejunal bypass surgery benefits rats with type 2-like diabetes. Obes. Surg. 24:3 (2014), 405–411.
49. Jian, W., Peng, W., Xiao, S., Li, H., Jin, J., Qin, L., Dong, Y., Su, Q., Role of serum vaspin in progression of type 2 diabetes: a 2-year cohort study. Plos One, 9(4), 2014, e94763.
50. Sanlioglu, A.D., Altunbas, H.A., Balci, M.K., Griffith, T.S., Sanlioglu, S., Clinical utility of insulin and insulin analogs. Islets 5:2 (2013), 67–78.
51. Thorens, B., Gluco-incretin hormones in insulin secretion and diabetes. Med. Sci.: M/S 19:8–9 (2003), 860–863.
52. Catena, C., Giacchetti, G., Novello, M., Colussi, G., Cavarape, A., Sechi, L.A., Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension. Am. J. Hypertens. 16:11 Pt. 1 (2003), 973–978.
53. Ozturk, K., High-fat diet and low-dose streptozotocin induced type 2 diabetes: a methodological critique. Appl. Med. Res. 2 (2016), 41–42.