Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4

Drug Design, Development and Therapy

Volumn 10, Issue , 2016, Pages 2193-2202

  Runtuwene, Joshua ^a,b   Cheng, Kai Chun ^a   Asakawa, Akihiro ^a   Amitani, Haruka ^a   Amitani, Marie ^a   Morinaga, Akinori ^a   Takimoto, Yoshiyuki ^c   Kairupan, Bernabas Harold Ralph ^b   Inui, Akio ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b SAM RATULANGI UNIVERSITY   (Indonesia)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Diabetes mellitus; GLUT4; HFD; HOMA IR; PEPCK; STZ

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); ROSMARINIC ACID; ANTIDIABETIC AGENT; CINNAMIC ACID DERIVATIVE; DEPSIDE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; GENE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE UTILIZATION; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID DIET; LOW DRUG DOSE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; RAT; SKELETAL MUSCLE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TREATMENT DURATION; ANIMAL; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; METABOLISM;

ANIMALS; CINNAMATES; DEPSIDES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MUSCLE, SKELETAL; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RATS; STREPTOZOCIN;

EID: 84978701130     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S108539     Document Type: Article

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