-
1
-
-
0242363251
-
With your genes? Take one of these, three times a day
-
Abbott, A. (2003). With your genes? Take one of these, three times a day. Nature, 425(6960), 760–762.
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 760-762
-
-
Abbott, A.1
-
2
-
-
85048668308
-
-
. IRESSA—gefitinib tablet, coated [package insert]. AstraZeneca Pharmaceuticals LP, Delaware
-
AstraZeneca Pharmaceuticals LP. (2015). IRESSA—gefitinib tablet, coated [package insert]. AstraZeneca Pharmaceuticals LP, Delaware.
-
(2015)
-
-
-
3
-
-
84898540382
-
PharmGKB summary: Abacavir pathway
-
Barbarino, J. M., Kroetz, D. L., Altman, R. B., & Klein, T. E. (2014). PharmGKB summary: Abacavir pathway. Pharmacogenetics and Genomics, 24(5), 276–282.
-
(2014)
Pharmacogenetics and Genomics
, vol.24
, Issue.5
, pp. 276-282
-
-
Barbarino, J.M.1
Kroetz, D.L.2
Altman, R.B.3
Klein, T.E.4
-
4
-
-
84856343062
-
Human leukocyte antigen (HLA) and pharmacogenetics: Screening for HLA-B*57:01 among human immunodeficiency virus-positive patients from southern Alberta
-
Berka, N., Gill, J. M., Liacini, A., O'Bryan, T., & Khan, F. M. (2012). Human leukocyte antigen (HLA) and pharmacogenetics: Screening for HLA-B*57:01 among human immunodeficiency virus-positive patients from southern Alberta. Human Immunology, 73(2), 164–167.
-
(2012)
Human Immunology
, vol.73
, Issue.2
, pp. 164-167
-
-
Berka, N.1
Gill, J.M.2
Liacini, A.3
O'Bryan, T.4
Khan, F.M.5
-
5
-
-
84900854522
-
Incorporation of pharmacogenomics into routine clinical practice: The clinical pharmacogenetics implementation consortium (CPIC) guideline development process
-
Caudle, K. E., Klein, T. E., Hoffman, J. M., Muller, D. J., Whirl-Carrillo, M., Gong, L., … Johnson, S. G. (2014). Incorporation of pharmacogenomics into routine clinical practice: The clinical pharmacogenetics implementation consortium (CPIC) guideline development process. Current Drug Metabolism, 15(2), 209–217.
-
(2014)
Current Drug Metabolism
, vol.15
, Issue.2
, pp. 209-217
-
-
Caudle, K.E.1
Klein, T.E.2
Hoffman, J.M.3
Muller, D.J.4
Whirl-Carrillo, M.5
Gong, L.6
Johnson, S.G.7
-
6
-
-
85048672947
-
Mercaptopurine therapy and TPMT genotype
-
In Pratt V, McLeod H, Dean L, et al., eds., Bethesda, MD National Center for Biotechnology Information. Retrieved fro
-
Dean L. (2012). Mercaptopurine therapy and TPMT genotype. In Pratt V, McLeod H, Dean L, et al., eds. Medical genetics summaries. Bethesda, MD: National Center for Biotechnology Information. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK100660/
-
(2012)
Medical genetics summaries
-
-
Dean, L.1
-
7
-
-
84920866837
-
Preemptive clinical pharmacogenetics implementation: Current programs in five US medical centers
-
Dunnenberger, H. M., Crews, K. R., Hoffman, J. M., Caudle, K. E., Broeckel, U., Howard, S. C., … Relling, M. V. (2015). Preemptive clinical pharmacogenetics implementation: Current programs in five US medical centers. Annual Review of Pharmacology and Toxicology, 55, 89–106.
-
(2015)
Annual Review of Pharmacology and Toxicology
, vol.55
, pp. 89-106
-
-
Dunnenberger, H.M.1
Crews, K.R.2
Hoffman, J.M.3
Caudle, K.E.4
Broeckel, U.5
Howard, S.C.6
Relling, M.V.7
-
8
-
-
85048699599
-
-
. HERCEPTIN (trastuzumab) for injection, for intravenous use. Genentech, Inc, California
-
Genentech, Inc. (2015). HERCEPTIN (trastuzumab) for injection, for intravenous use. Genentech, Inc, California.
-
(2015)
-
-
-
9
-
-
85048654074
-
-
. ZELBORAF (vemurafenib) [pacakge insert]. Genentech USA, Inc. California
-
Genentech USA, Inc. (2016). ZELBORAF (vemurafenib) [pacakge insert]. Genentech USA, Inc. California.
-
(2016)
-
-
-
10
-
-
84925335327
-
Ethical and public policy challenges for pharmacogenomics
-
Gershon, E. S., Alliey-Rodriguez, N., & Grennan, K. (2014). Ethical and public policy challenges for pharmacogenomics. Dialogues in Clinical Neuroscience, 16(4), 567–574.
-
(2014)
Dialogues in Clinical Neuroscience
, vol.16
, Issue.4
, pp. 567-574
-
-
Gershon, E.S.1
Alliey-Rodriguez, N.2
Grennan, K.3
-
11
-
-
84875933982
-
Genomic medicine
-
Retrieved fro
-
Goodman, D. M., Cassio, L., & Livingstone, E. H. (2013). Genomic medicine. Journal of the American Medical Association, 309(14), 1544. Retrieved from http://jamanetwork.com/journals/jama/fullarticle/1677375
-
(2013)
Journal of the American Medical Association
, vol.309
, Issue.14
, pp. 1544
-
-
Goodman, D.M.1
Cassio, L.2
Livingstone, E.H.3
-
12
-
-
85048682493
-
Somatic versus germinal mutation
-
Lewontin R. C.Gelbart W. M. (, 7th, ed.)., New York, NY, W.H. Freema
-
Griffiths, A. J. F., Miller, J. H., Suzuki, D. T., Lewontin R. C., & Gelbart W. M. (2000). Somatic versus germinal mutation. In An introduction to genetic analysis (7th ed.). New York, NY: W.H. Freeman.
-
(2000)
An introduction to genetic analysis
-
-
Griffiths, A.J.F.1
Miller, J.H.2
Suzuki, D.T.3
-
13
-
-
84862979660
-
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
-
Illing, P. T., Vivian, J. P., Dudek, N. L., Kostenko, L., Chen, Z., Bharadwaj, M., … McCluskey, J. (2012). Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature, 486(7404), 554–558.
-
(2012)
Nature
, vol.486
, Issue.7404
, pp. 554-558
-
-
Illing, P.T.1
Vivian, J.P.2
Dudek, N.L.3
Kostenko, L.4
Chen, Z.5
Bharadwaj, M.6
McCluskey, J.7
-
14
-
-
84872050511
-
Pharmacogenomics
-
Karczewski, K. J., Daneshjou, R., & Altman, R. B. (2012). Pharmacogenomics. PLoS Computational Biology, 8(12), e1002817.
-
(2012)
PLoS Computational Biology
, vol.8
, Issue.12
-
-
Karczewski, K.J.1
Daneshjou, R.2
Altman, R.B.3
-
15
-
-
0035755351
-
Integrating genotype and phenotype information: An overview of the PharmGKB project. Pharmacogenetics research network and knowledge base
-
Klein, T. E., Chang, J. T., Cho, M. K., Easton, K. L., Fergerson, R., Hewett, M., … Altman, R. B. (2001). Integrating genotype and phenotype information: An overview of the PharmGKB project. Pharmacogenetics research network and knowledge base. The Pharmacogenomics Journal, 1(3), 167–170.
-
(2001)
The Pharmacogenomics Journal
, vol.1
, Issue.3
, pp. 167-170
-
-
Klein, T.E.1
Chang, J.T.2
Cho, M.K.3
Easton, K.L.4
Fergerson, R.5
Hewett, M.6
Altman, R.B.7
-
16
-
-
85048658733
-
PharmCAT: A Pharmacogenomics Clinical Annotation Tool
-
Klein, T. E.Ritchie, M
-
Klein, T. E., & Ritchie, M. D. (2017). PharmCAT: A Pharmacogenomics Clinical Annotation Tool. Clinical Pharmacology and Therapeutics. https://www.ncbi.nlm.nih.gov/pubmed/29194583
-
(2017)
Clinical Pharmacology and Therapeutics
-
-
-
17
-
-
85048677566
-
-
Linkoping, Sweden Linkoping University. Retrieved fro
-
Linköping University, Institutionen för Medicin Och Hälsa. (2013). TPMT alleles. Linkoping, Sweden: Linkoping University. Retrieved from https://www.imh.liu.se/tpmtalleles?l=en
-
(2013)
TPMT alleles
-
-
-
18
-
-
85020388874
-
The pharmacogenomics research network translational pharmacogenetics program: Outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems
-
Luzum, J. A., Pakyz, R. E., Elsey, A. R., Haidar, C. E., Peterson, J. F., Whirl-Carrillo, M., … for the Pharmacogenomics Research Network Translational Pharmacogenetics Program (2017). The pharmacogenomics research network translational pharmacogenetics program: Outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems. Clinical Pharmacology and Therapeutics, 102(3), 502–510.
-
(2017)
Clinical Pharmacology and Therapeutics
, vol.102
, Issue.3
, pp. 502-510
-
-
Luzum, J.A.1
Pakyz, R.E.2
Elsey, A.R.3
Haidar, C.E.4
Peterson, J.F.5
Whirl-Carrillo, M.6
-
19
-
-
84899417586
-
Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing: 2014 update
-
Martin, M. A., Hoffman, J. M., Freimuth, R. R., Klein, T. E., Dong, B. J., Pirmohamed, M., … Kroetz, D. L. (2014). Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing: 2014 update. Clinical Pharmacology and Therapeutics, 95(5), 499–500.
-
(2014)
Clinical Pharmacology and Therapeutics
, vol.95
, Issue.5
, pp. 499-500
-
-
Martin, M.A.1
Hoffman, J.M.2
Freimuth, R.R.3
Klein, T.E.4
Dong, B.J.5
Pirmohamed, M.6
Kroetz, D.L.7
-
20
-
-
84942236803
-
Somatic mutation in cancer and normal cells
-
Martincorena, I., & Campbell, P. J. (2015). Somatic mutation in cancer and normal cells. Science, 349(6255), 1483–1489.
-
(2015)
Science
, vol.349
, Issue.6255
, pp. 1483-1489
-
-
Martincorena, I.1
Campbell, P.J.2
-
21
-
-
82755166898
-
From pharmacogenomic knowledge acquisition to clinical applications: The PharmGKB as a clinical pharmacogenomic biomarker resource
-
McDonagh, E. M., Whirl-Carrillo, M., Garten, Y., Altman, R. B., & Klein, T. E. (2011). From pharmacogenomic knowledge acquisition to clinical applications: The PharmGKB as a clinical pharmacogenomic biomarker resource. Biomarkers in Medicine, 5(6), 795–806.
-
(2011)
Biomarkers in Medicine
, vol.5
, Issue.6
, pp. 795-806
-
-
McDonagh, E.M.1
Whirl-Carrillo, M.2
Garten, Y.3
Altman, R.B.4
Klein, T.E.5
-
22
-
-
84863721147
-
Abacavir induces loading of novel self-peptides into HLA-B*57: 01: An autoimmune model for HLA-associated drug hypersensitivity
-
Norcross, M. A., Luo, S., Lu, L., Boyne, M. T., Gomarteli, M., Rennels, A. D., … Buchli, R. (2012). Abacavir induces loading of novel self-peptides into HLA-B*57: 01: An autoimmune model for HLA-associated drug hypersensitivity. AIDS, 26(11), F21–F29.
-
(2012)
AIDS
, vol.26
, Issue.11
, pp. F21-F29
-
-
Norcross, M.A.1
Luo, S.2
Lu, L.3
Boyne, M.T.4
Gomarteli, M.5
Rennels, A.D.6
Buchli, R.7
-
23
-
-
84862532297
-
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire
-
Ostrov, D. A., Grant, B. J., Pompeu, Y. A., Sidney, J., Harndahl, M., Southwood, S., … Peters, B. (2012). Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proceedings of the National Academy of Sciences of the United States of America, 109(25), 9959–9964.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.25
, pp. 9959-9964
-
-
Ostrov, D.A.1
Grant, B.J.2
Pompeu, Y.A.3
Sidney, J.4
Harndahl, M.5
Southwood, S.6
Peters, B.7
-
24
-
-
85010372634
-
Principles of pharmacokinetics
-
D. W. Kufe, R. E. Pollock, R. R. Weichselbaum, (Eds.),, 6th, ed.)., BC Decker, Hamilton, O
-
Ratain, M. J., & Plunkett Jr., W. K. (2003). Principles of pharmacokinetics. In D. W. Kufe, R. E. Pollock, R. R. Weichselbaum, et al. (Eds.), Holland-Frei cancer medicine (6th ed.). BC Decker: Hamilton, ON.
-
(2003)
Holland-Frei cancer medicine
-
-
Ratain, M.J.1
Plunkett, W.K.2
-
25
-
-
84944311937
-
Pharmacogenomics in the clinic
-
Relling, M. V., & Evans, W. E. (2015). Pharmacogenomics in the clinic. Nature, 526(7573), 343–350.
-
(2015)
Nature
, vol.526
, Issue.7573
, pp. 343-350
-
-
Relling, M.V.1
Evans, W.E.2
-
26
-
-
84875438476
-
Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update
-
Relling, M. V., Gardner, E. E., Sandborn, W. J., Schmiegelow, K., Pui, C. H., Yee, S. W., … Clinical Pharmacogenetics Implementation Consortium (2013). Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update. Clinical Pharmacology and Therapeutics, 93(4), 324–325.
-
(2013)
Clinical Pharmacology and Therapeutics
, vol.93
, Issue.4
, pp. 324-325
-
-
Relling, M.V.1
Gardner, E.E.2
Sandborn, W.J.3
Schmiegelow, K.4
Pui, C.H.5
Yee, S.W.6
-
27
-
-
79951809968
-
Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing
-
Relling, M. V., Gardner, E. E., Sandborn, W. J., Schmiegelow, K., Pui, C. H., Yee, S. W., … Klein, T. E. (2011). Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clinical Pharmacology and Therapeutics, 89(3), 387–391.
-
(2011)
Clinical Pharmacology and Therapeutics
, vol.89
, Issue.3
, pp. 387-391
-
-
Relling, M.V.1
Gardner, E.E.2
Sandborn, W.J.3
Schmiegelow, K.4
Pui, C.H.5
Yee, S.W.6
Klein, T.E.7
-
28
-
-
79951809825
-
CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
-
Relling, M. V., & Klein, T. E. (2011). CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network. Clinical Pharmacology and Therapeutics, 89(3), 464–467.
-
(2011)
Clinical Pharmacology and Therapeutics
, vol.89
, Issue.3
, pp. 464-467
-
-
Relling, M.V.1
Klein, T.E.2
-
29
-
-
78349268004
-
The Canadian pharmacogenomics network for drug safety: A model for safety pharmacology
-
Ross, C. J., Visscher, H., Sistonen, J., Brunham, L. R., Pussegoda, K., Loo, T. T., … Hayden, M. R. (2010). The Canadian pharmacogenomics network for drug safety: A model for safety pharmacology. Thyroid, 20(7), 681–687.
-
(2010)
Thyroid
, vol.20
, Issue.7
, pp. 681-687
-
-
Ross, C.J.1
Visscher, H.2
Sistonen, J.3
Brunham, L.R.4
Pussegoda, K.5
Loo, T.T.6
Hayden, M.R.7
-
30
-
-
82955233708
-
Personalizing medicine with clinical pharmacogenetics
-
Scott, S. A. (2011). Personalizing medicine with clinical pharmacogenetics. Genetics in Medicine, 13(12), 987–995.
-
(2011)
Genetics in Medicine
, vol.13
, Issue.12
, pp. 987-995
-
-
Scott, S.A.1
-
31
-
-
79955463893
-
Pharmacogenetics: From bench to byte—an update of guidelines
-
Swen, J. J., Nijenhuis, M., de Boer, A., Grandia, L., Maitland-van der Zee, A. H., Mulder, H., … Guchelaar, H. J. (2011). Pharmacogenetics: From bench to byte—an update of guidelines. Clinical Pharmacology and Therapeutics, 89(5), 662–673.
-
(2011)
Clinical Pharmacology and Therapeutics
, vol.89
, Issue.5
, pp. 662-673
-
-
Swen, J.J.1
Nijenhuis, M.2
de Boer, A.3
Grandia, L.4
Maitland-van der Zee, A.H.5
Mulder, H.6
Guchelaar, H.J.7
-
32
-
-
42349098097
-
Pharmacogenetics: From bench to byte
-
Swen, J. J., Wilting, I., de Goede, A. L., Grandia, L., Mulder, H., Touw, D. J., … Deneer, V. H. (2008). Pharmacogenetics: From bench to byte. Clinical Pharmacology and Therapeutics, 83(5), 781–787.
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.5
, pp. 781-787
-
-
Swen, J.J.1
Wilting, I.2
de Goede, A.L.3
Grandia, L.4
Mulder, H.5
Touw, D.J.6
Deneer, V.H.7
-
33
-
-
85048655247
-
-
. Retrieved fro
-
The Precision Medicine Initiative. (2015). Retrieved from https://obamawhitehouse.archives.gov/node/333101
-
(2015)
-
-
-
34
-
-
77950352522
-
Pharmacogenomics and bioinformatics: PharmGKB
-
Thorn, C. F., Klein, T. E., & Altman, R. B. (2010). Pharmacogenomics and bioinformatics: PharmGKB. Pharmacogenomics, 11(4), 501–505.
-
(2010)
Pharmacogenomics
, vol.11
, Issue.4
, pp. 501-505
-
-
Thorn, C.F.1
Klein, T.E.2
Altman, R.B.3
-
35
-
-
85048682462
-
-
. ZIAGEN—abacavir sulfate tablet, film-coated [package insert]. ViiV Healthcare Company, Canada
-
ViiV Healthcare Company. (2015). ZIAGEN—abacavir sulfate tablet, film-coated [package insert]. ViiV Healthcare Company, Canada.
-
(2015)
-
-
-
36
-
-
85048669839
-
-
. Ziagen 300 mg film-coated tablets [package insert]. ViiV Healthcare UK Limited, UK
-
ViiV Healthcare UK Limited. (2017). Ziagen 300 mg film-coated tablets [package insert]. ViiV Healthcare UK Limited, UK.
-
(2017)
-
-
-
37
-
-
85048694372
-
-
ZIAGEN—abacavir tablets 300 mg (as abacavir sulfate). Abacavir oral solution, 20 mg/ml (as abacavir sulfate) [package insert]. ViiV Healthcare ULC, Quebec
-
ViiV Healthcare ULC. (2015) ZIAGEN—abacavir tablets 300 mg (as abacavir sulfate). Abacavir oral solution, 20 mg/ml (as abacavir sulfate) [package insert]. ViiV Healthcare ULC, Quebec.
-
(2015)
-
-
-
38
-
-
77950343855
-
Very important pharmacogene summary: Thiopurine S-methyltransferase
-
Wang, L., Pelleymounter, L., Weinshilboum, R., Johnson, J. A., Hebert, J. M., Altman, R. B., & Klein, T. E. (2010). Very important pharmacogene summary: Thiopurine S-methyltransferase. Pharmacogenetics and Genomics, 20(6), 401–405.
-
(2010)
Pharmacogenetics and Genomics
, vol.20
, Issue.6
, pp. 401-405
-
-
Wang, L.1
Pelleymounter, L.2
Weinshilboum, R.3
Johnson, J.A.4
Hebert, J.M.5
Altman, R.B.6
Klein, T.E.7
-
39
-
-
33750332747
-
Pharmacogenetics and pharmacogenomics: Development, science, and translation
-
Weinshilboum, R. M., & Wang, L. (2006). Pharmacogenetics and pharmacogenomics: Development, science, and translation. Annual Review of Genomics and Human Genetics, 7, 223–245.
-
(2006)
Annual Review of Genomics and Human Genetics
, vol.7
, pp. 223-245
-
-
Weinshilboum, R.M.1
Wang, L.2
-
40
-
-
77955869124
-
Thiopurine pathway
-
Zaza, G., Cheok, M., Krynetskaia, N., Thorn, C., Stocco, G., Hebert, J. M., … Altman, R. B. (2010). Thiopurine pathway. Pharmacogenetics and Genomics, 20(9), 573–574.
-
(2010)
Pharmacogenetics and Genomics
, vol.20
, Issue.9
, pp. 573-574
-
-
Zaza, G.1
Cheok, M.2
Krynetskaia, N.3
Thorn, C.4
Stocco, G.5
Hebert, J.M.6
Altman, R.B.7
|