Somatic mutation in cancer and normal cells

Science

Volumn 349, Issue 6255, 2015, Pages 1483-1489

  Martincorena, Iñigo ^a   Campbell, Peter J ^a,b  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; DINUCLEOTIDE; PYRIMIDINE DIMER; REACTIVE OXYGEN METABOLITE;

AGING; CANCER; CELLS AND CELL COMPONENTS; DISABILITY; DISEASE SPREAD; GENE EXPRESSION; MUTATION; NUCLEIC ACID ANALYSIS;

CANCER CELL; CANCER GROWTH; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; GENE SEQUENCE; GENOME; GERMLINE MUTATION; HOMOLOGOUS RECOMBINATION; IMMUNOSURVEILLANCE; INDEL MUTATION; LUNG CANCER; MALIGNANT TRANSFORMATION; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE; POINT MUTATION; PRECANCER; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SENESCENCE; SOMATIC CELL; SOMATIC MUTATION; T LYMPHOCYTE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; AGING; GENETICS; HUMAN; HUMAN GENOME; MOLECULAR EVOLUTION; MUTAGENESIS; MUTATION; NEOPLASMS; NUCLEOTIDE SEQUENCE;

AGING; DNA MUTATIONAL ANALYSIS; EVOLUTION, MOLECULAR; GENOME, HUMAN; HUMANS; MUTAGENESIS; MUTATION; NEOPLASMS;

EID: 84942236803     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab4082     Document Type: Review

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