메뉴 건너뛰기




Volumn 36, Issue 12, 2018, Pages 1592-1598

Genetic and subunit vaccines based on the stem domain of the equine influenza hemagglutinin provide homosubtypic protection against heterologous strains

Author keywords

Conserved epitopes; Cross protection; Equine influenza virus; Hemagglutinin stem region; Lethal challenge

Indexed keywords

DNA VACCINE; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; SUBUNIT VACCINE; RECOMBINANT PROTEIN; RECOMBINANT VACCINE;

EID: 85042013601     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2018.02.019     Document Type: Article
Times cited : (4)

References (43)
  • 1
    • 84889080547 scopus 로고    scopus 로고
    • Equine influenza—a global perspective
    • Cullinane, A., Newton, J.R., Equine influenza—a global perspective. Vet Microbiol 167:1–2 (Nov. 2013), 205–214.
    • (2013) Vet Microbiol , vol.167 , Issue.1-2 , pp. 205-214
    • Cullinane, A.1    Newton, J.R.2
  • 2
    • 84922480756 scopus 로고    scopus 로고
    • A brief introduction to equine influenza and equine influenza viruses;
    • Chambers TM. A brief introduction to equine influenza and equine influenza viruses; 2014. p. 365–70.
    • (2014) , pp. 365-70
    • Chambers, T.M.1
  • 3
    • 85016905549 scopus 로고    scopus 로고
    • A systematic review of recent advances in equine influenza vaccination
    • Paillot, R., A systematic review of recent advances in equine influenza vaccination. Vaccines 2:4 (2014), 797–831.
    • (2014) Vaccines , vol.2 , Issue.4 , pp. 797-831
    • Paillot, R.1
  • 5
    • 85040771708 scopus 로고    scopus 로고
    • Molecular epidemiology and spatio-temporal dynamics of the H3N8 equine influenza virus in South America
    • Perglione, C., Golemba, M., Torres, C., Barrandeguy, M., Molecular epidemiology and spatio-temporal dynamics of the H3N8 equine influenza virus in South America. Pathogens, 5(4), Oct. 2016, 61.
    • (2016) Pathogens , vol.5 , Issue.4 , pp. 61
    • Perglione, C.1    Golemba, M.2    Torres, C.3    Barrandeguy, M.4
  • 6
    • 0023082135 scopus 로고
    • The structure and function of the hemagglutinin membrane glycoprotein of influenza virus
    • Wiley, D.C., Skehel, J.J., The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem 56:1 (1987), 365–394.
    • (1987) Annu Rev Biochem , vol.56 , Issue.1 , pp. 365-394
    • Wiley, D.C.1    Skehel, J.J.2
  • 7
    • 84864035688 scopus 로고    scopus 로고
    • Molecular basis of the structure and function of H1 hemagglutinin of influenza virus
    • Sriwilaijaroen, N., Suzuki, Y., Molecular basis of the structure and function of H1 hemagglutinin of influenza virus. Proc Jpn Acad Ser B Phys Biol Sci 88:6 (2012), 226–249.
    • (2012) Proc Jpn Acad Ser B Phys Biol Sci , vol.88 , Issue.6 , pp. 226-249
    • Sriwilaijaroen, N.1    Suzuki, Y.2
  • 8
    • 79952140653 scopus 로고    scopus 로고
    • Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio, no. 1; May 2010 p. e00018-10–e00018-10.
    • Steel J, et al. Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio, vol. 1, no. 1; May 2010 p. e00018-10–e00018-10.
    • , vol.1
    • Steel, J.1
  • 9
    • 64849114224 scopus 로고    scopus 로고
    • Antibody recognition of a highly conserved influenza virus epitope
    • Ekiert, D.C., et al. Antibody recognition of a highly conserved influenza virus epitope. Science (80-.) 324:5924 (2009), 246–251.
    • (2009) Science (80-.) , vol.324 , Issue.5924 , pp. 246-251
    • Ekiert, D.C.1
  • 10
    • 0027471177 scopus 로고
    • A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains
    • Okuno, Y., Isegawa, Y., Sasao, F., Ueda, S., A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J Virol 67:5 (May 1993), 2552–2558.
    • (1993) J Virol , vol.67 , Issue.5 , pp. 2552-2558
    • Okuno, Y.1    Isegawa, Y.2    Sasao, F.3    Ueda, S.4
  • 11
    • 58049198443 scopus 로고    scopus 로고
    • Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from Human IgM+ Memory B Cells
    • Throsby, M., et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from Human IgM+ Memory B Cells. PLoS One, 3(12), Dec. 2008, e3942.
    • (2008) PLoS One , vol.3 , Issue.12 , pp. e3942
    • Throsby, M.1
  • 12
    • 62049083943 scopus 로고    scopus 로고
    • Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
    • Sui, J., et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 16:3 (Mar. 2009), 265–273.
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.3 , pp. 265-273
    • Sui, J.1
  • 13
    • 84863597077 scopus 로고    scopus 로고
    • A Pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo
    • Tan, G.S., Krammer, F., Eggink, D., Kongchanagul, A., Moran, T.M., Palese, P., A Pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. J Virol 86:11 (2012), 6179–6188.
    • (2012) J Virol , vol.86 , Issue.11 , pp. 6179-6188
    • Tan, G.S.1    Krammer, F.2    Eggink, D.3    Kongchanagul, A.4    Moran, T.M.5    Palese, P.6
  • 14
    • 77649242815 scopus 로고    scopus 로고
    • Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins
    • Wang, T.T., et al. Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins. PLoS Pathog, 6(2), Feb. 2010, e1000796.
    • (2010) PLoS Pathog , vol.6 , Issue.2 , pp. e1000796
    • Wang, T.T.1
  • 15
    • 80051635697 scopus 로고    scopus 로고
    • A highly conserved neutralizing epitope on Group 2 influenza A viruses
    • Aug
    • Ekiert, D.C., et al. A highly conserved neutralizing epitope on Group 2 influenza A viruses. Science (80-.) 333:6044 (2011), 843–850 Aug.
    • (2011) Science (80-.) , vol.333 , Issue.6044 , pp. 843-850
    • Ekiert, D.C.1
  • 16
    • 84885950726 scopus 로고    scopus 로고
    • Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses
    • Margine, I., et al. Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses. J Virol 87:19 (2013), 10435–10446.
    • (2013) J Virol , vol.87 , Issue.19 , pp. 10435-10446
    • Margine, I.1
  • 17
    • 84891910969 scopus 로고    scopus 로고
    • A common solution to group 2 influenza virus neutralization
    • Friesen, R.H.E., et al. A common solution to group 2 influenza virus neutralization. Proc Natl Acad Sci 111:1 (Jan. 2014), 445–450.
    • (2014) Proc Natl Acad Sci , vol.111 , Issue.1 , pp. 445-450
    • Friesen, R.H.E.1
  • 18
    • 80051670323 scopus 로고    scopus 로고
    • A neutralizing antibody selected from plasma cells that binds to group 1 and Group 2 influenza A hemagglutinins
    • Corti, D., et al. A neutralizing antibody selected from plasma cells that binds to group 1 and Group 2 influenza A hemagglutinins. Science (80-.) 333:6044 (2011), 850–856.
    • (2011) Science (80-.) , vol.333 , Issue.6044 , pp. 850-856
    • Corti, D.1
  • 19
    • 84866953140 scopus 로고    scopus 로고
    • Cross-neutralization of influenza A viruses mediated by a single antibody loop
    • Ekiert, D.C., et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature 489:7417 (Sep. 2012), 526–532.
    • (2012) Nature , vol.489 , Issue.7417 , pp. 526-532
    • Ekiert, D.C.1
  • 20
    • 0030013837 scopus 로고    scopus 로고
    • The immunological activity of a deletion mutant of influenza virus haemagglutinin lacking the globular region
    • Sagawa, H., Ohshima, A., Kato, I., Okuno, Y., Isegawa, Y., The immunological activity of a deletion mutant of influenza virus haemagglutinin lacking the globular region. J Gen Virol 77:7 (1996), 1483–1487.
    • (1996) J Gen Virol , vol.77 , Issue.7 , pp. 1483-1487
    • Sagawa, H.1    Ohshima, A.2    Kato, I.3    Okuno, Y.4    Isegawa, Y.5
  • 21
    • 45549102325 scopus 로고    scopus 로고
    • Antibodies induced by the HA2 glycopolypeptide of influenza virus haemagglutinin improve recovery from influenza A virus infection
    • Gocnik, M., et al. Antibodies induced by the HA2 glycopolypeptide of influenza virus haemagglutinin improve recovery from influenza A virus infection. J Gen Virol 89:4 (2008), 958–967.
    • (2008) J Gen Virol , vol.89 , Issue.4 , pp. 958-967
    • Gocnik, M.1
  • 22
    • 77956379133 scopus 로고    scopus 로고
    • Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge
    • Bommakanti, G., et al. Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge. Proc Natl Acad Sci 107:31 (Aug. 2010), 13701–13706.
    • (2010) Proc Natl Acad Sci , vol.107 , Issue.31 , pp. 13701-13706
    • Bommakanti, G.1
  • 23
    • 84870656355 scopus 로고    scopus 로고
    • Design of escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge
    • Bommakanti, G., et al. Design of escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge. J Virol 86:24 (2012), 13434–13444.
    • (2012) J Virol , vol.86 , Issue.24 , pp. 13434-13444
    • Bommakanti, G.1
  • 24
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
    • Krammer, F., Pica, N., Hai, R., Margine, I., Palese, P., Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. J Virol 87:12 (Jun. 2013), 6542–6550.
    • (2013) J Virol , vol.87 , Issue.12 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palese, P.5
  • 25
    • 84877620734 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies against influenza viruses
    • Laursen, N.S., Wilson, I.A., Broadly neutralizing antibodies against influenza viruses. Antiviral Res 98:3 (Jun. 2013), 476–483.
    • (2013) Antiviral Res , vol.98 , Issue.3 , pp. 476-483
    • Laursen, N.S.1    Wilson, I.A.2
  • 26
    • 84885953445 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin stalk-based antibodies and vaccines
    • Krammer, F., Palese, P., Influenza virus hemagglutinin stalk-based antibodies and vaccines. Curr Opin Virol 3:5 (2013), 521–530.
    • (2013) Curr Opin Virol , vol.3 , Issue.5 , pp. 521-530
    • Krammer, F.1    Palese, P.2
  • 27
    • 0842324614 scopus 로고    scopus 로고
    • Jump-starting the immune system: prime–boosting comes of age
    • Woodland, D.L., Jump-starting the immune system: prime–boosting comes of age. Trends Immunol 25:2 (Feb. 2004), 98–104.
    • (2004) Trends Immunol , vol.25 , Issue.2 , pp. 98-104
    • Woodland, D.L.1
  • 28
    • 67049086871 scopus 로고    scopus 로고
    • Heterologous prime–boost vaccination
    • Lu, S., Heterologous prime–boost vaccination. Curr Opin Immunol 21:3 (Jun. 2009), 346–351.
    • (2009) Curr Opin Immunol , vol.21 , Issue.3 , pp. 346-351
    • Lu, S.1
  • 29
    • 0033522456 scopus 로고    scopus 로고
    • Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene
    • Lunn, D.P., et al. Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene. Vaccine 17:18 (May 1999), 2245–2258.
    • (1999) Vaccine , vol.17 , Issue.18 , pp. 2245-2258
    • Lunn, D.P.1
  • 30
    • 0038722278 scopus 로고    scopus 로고
    • Regional antibody and cellular immune responses to equine influenza virus infection, and particle mediated DNA vaccination
    • Soboll, G., et al. Regional antibody and cellular immune responses to equine influenza virus infection, and particle mediated DNA vaccination. Vet Immunol Immunopathol 94:1–2 (2003), 47–62.
    • (2003) Vet Immunol Immunopathol , vol.94 , Issue.1-2 , pp. 47-62
    • Soboll, G.1
  • 31
    • 84861199412 scopus 로고    scopus 로고
    • Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies
    • Ault, A., et al. Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies. Vaccine 30:26 (Jun. 2012), 3965–3974.
    • (2012) Vaccine , vol.30 , Issue.26 , pp. 3965-3974
    • Ault, A.1
  • 32
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of the M2 protein
    • Fiers, W., Neirynck, S., Deroo, T., Saelens, X., Vanlandschoot, P., Jou, W.M., A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat Med 5:10 (Oct. 1999), 1157–1163.
    • (1999) Nat Med , vol.5 , Issue.10 , pp. 1157-1163
    • Fiers, W.1    Neirynck, S.2    Deroo, T.3    Saelens, X.4    Vanlandschoot, P.5    Jou, W.M.6
  • 34
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa, H., Yamamura, K., Miyazaki, J., Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:2 (1991), 193–199.
    • (1991) Gene , vol.108 , Issue.2 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 35
    • 84870671459 scopus 로고    scopus 로고
    • Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly
    • Verhelst, J., Parthoens, E., Schepens, B., Fiers, W., Saelens, X., Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly. J Virol 86:24 (Dec. 2012), 13445–13455.
    • (2012) J Virol , vol.86 , Issue.24 , pp. 13445-13455
    • Verhelst, J.1    Parthoens, E.2    Schepens, B.3    Fiers, W.4    Saelens, X.5
  • 36
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • Reed, L.J., Muench, H., A simple method of estimating fifty per cent endpoints. Am J Epidemiol 27:3 (May 1938), 493–497.
    • (1938) Am J Epidemiol , vol.27 , Issue.3 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 37
    • 84907703696 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin as a vaccine antigen produced in bacteria
    • Sączyńska, V., Influenza virus hemagglutinin as a vaccine antigen produced in bacteria. Acta Biochim Pol 61:3 (2014), 561–572.
    • (2014) Acta Biochim Pol , vol.61 , Issue.3 , pp. 561-572
    • Sączyńska, V.1
  • 38
    • 70849114731 scopus 로고    scopus 로고
    • Glycans on influenza hemagglutinin affect receptor binding and immune response
    • Wang, C.-C., et al. Glycans on influenza hemagglutinin affect receptor binding and immune response. Proc Natl Acad Sci 106:43 (2009), 18137–18142.
    • (2009) Proc Natl Acad Sci , vol.106 , Issue.43 , pp. 18137-18142
    • Wang, C.-C.1
  • 39
    • 84862936213 scopus 로고    scopus 로고
    • Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines
    • Xuan, C., Shi, Y., Qi, J., Zhang, W., Xiao, H., Gao, G.F., Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines. Protein Cell 2:12 (2011), 997–1005.
    • (2011) Protein Cell , vol.2 , Issue.12 , pp. 997-1005
    • Xuan, C.1    Shi, Y.2    Qi, J.3    Zhang, W.4    Xiao, H.5    Gao, G.F.6
  • 40
    • 85014069151 scopus 로고    scopus 로고
    • Universal influenza virus vaccines and therapeutic antibodies
    • Nachbagauer, R., Krammer, F., Universal influenza virus vaccines and therapeutic antibodies. Clin Microbiol Infect 23:4 (2017), 222–228.
    • (2017) Clin Microbiol Infect , vol.23 , Issue.4 , pp. 222-228
    • Nachbagauer, R.1    Krammer, F.2
  • 41
    • 84929332719 scopus 로고    scopus 로고
    • Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules
    • Grødeland, G., Bogen, B., Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules. Expert Rev Vaccines 14:6 (2015), 805–814.
    • (2015) Expert Rev Vaccines , vol.14 , Issue.6 , pp. 805-814
    • Grødeland, G.1    Bogen, B.2
  • 42
    • 84941023600 scopus 로고    scopus 로고
    • Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
    • Yassine, H.M., et al. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nat Med 21:9 (2015), 1065–1070.
    • (2015) Nat Med , vol.21 , Issue.9 , pp. 1065-1070
    • Yassine, H.M.1
  • 43
    • 84903476533 scopus 로고    scopus 로고
    • Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection
    • Mallajosyula, V.V.A., et al. Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection. Proc Natl Acad Sci 111:25 (2014), E2514–E2523.
    • (2014) Proc Natl Acad Sci , vol.111 , Issue.25 , pp. E2514-E2523
    • Mallajosyula, V.V.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.