Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene

Vaccine

Volumn 17, Issue 18, 1999, Pages 2245-2258

  Lunn, D P ^a   Soboll, G ^a   Schram, B R ^a   Quass, J ^a   McGregor, M W ^a   Drape, R J ^b   MacKlin, M D ^b   McCabe, D E ^b   Swain, W F ^b   Olsen, C W ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Powderject Vaccines   (United States)

Author keywords

Infectious immunity virus; Vaccination; Veterinary immunology

Indexed keywords

ANTIBODY; DNA VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFLUENZA VIRUS HEMAGGLUTININ; PLASMID DNA;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEMALE; GENE GUN; HORSE; INFLUENZA VIRUS; MALE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; SEROCONVERSION; VACCINATION; VIRUS GENE; VIRUS SHEDDING;

ANIMALS; ANTIBODIES, VIRAL; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HORSE DISEASES; HORSES; INFLUENZA A VIRUS; INFLUENZA VACCINES; MALE; ORTHOMYXOVIRIDAE INFECTIONS; VACCINES, DNA;

EID: 0033522456     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00496-4     Document Type: Article

References (69)

1. Mumford J.A. Progress in the control of equine influenza. In: Plowright W., Rossdale P.D., Wade J.F., editors. Equine infectious diseases VI. Proceedings of the Sixth International Conference. Newmarket: R&W Publications, 1992. p. 207-17.
2. Uppal P.K., Yadav M.P. Outbreak of equine influenza in India. Vet. Rec. 121:1987;569-570.
3. Webster R.G., Yuanje G. New influenza virus in horses. Nature. 351:1991;527.
4. Cullinane A.A. Viral respiratory disease. In: Robinson N.E., editor. Current therapy in equine medicine. 4th ed. Philadelphia: W.B. Saunders Company, 1997. p. 443-8.
5. Traub-Dargatz J.L., Salman M.D., Voss J.L. Medical problems of adult horses, as ranked by equine practitioners. J. Am. Vet. Med. Assoc. 198:1991;1745-1747.
6. Hannant D. Immune responses to common respiratory pathogens: problems and perspectives in equine immunology. Equine. Vet. J. Supplement 12:1991;10-19.
7. Tomoda T., Morita H., Kurashige T., Maassab H.F. Prevention of influenza by the intranasal administration of cold-recombinant, live-attenuated influenza virus vaccine: importance of interferon-gamma production and local IgA response. Vaccine. 13:1995;185-190.
8. Ada G.L., Jones P.D. The immune response to influenza infection. Curr. Top. Microbiol. Immunol. 128:1986;1-55.
9. Renegar K.B., Small P.A.J. Passive transfer of local immunity to influenza virus infection by IgA antibody. J. Immunol. 146:1991;1972-1978.
10. Renegar K.B. Influenza virus infections and immunity: a review of human and animal models. Lab. Anim. Sci. 42:1992;222-232.
11. Nelson K.M., Schram B.R., McGregor M.W., Olsen C.W., Lunn D.P. Local and systemic isotype-specific antibody responses to equine influenza virus infection versus conventional vaccination. Vaccine. 16:1998;1306-1313.
12. Mosmann T.R. Cytokine secretion patterns and cross-regulation of T-cell subsets. Immunol. Res. 10:1991;183-188.
13. Mosmann T.R., Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today. 17:1996;138-146.
14. McGhee J.R., Xu-Amano L., Miller C.J., Jackson R.J., Fujihashi K., Staats H.F., Kiyono H. The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract. Reprod. Fertil. Dev. 6:1994;369-379.
15. H2 responses. Immunol. Today. 12:1991;A49-A58.
16. McGhee J.R., Kiyono H. Mucosal immunity to vaccines: current concepts for vaccine development and immune response analysis. Adv. Exp. Med. Biol. 327:1992;3-12.
17. Vajdy M., Kosco Vilbois M.H., Kopf M., Kohler G., Lycke N. Impaired mucosal immune responses in interleukin 4-targeted mice. J. Exp. Med. 181:1995;41-53.
18. Hassett D.E., Whitton J.L. DNA immunization. Trends Microbiol. 8:1996;307-312.
19. Erd H.C., Xiang Z. Novel vaccine approaches. J. Immunol. 156:1996;3579-3582.
20. Erd H.C., Xiang Z.Q. Genetic immunization. Viral. Immunol. 9:1996;1-9.
21. Robinson H.L., Hunt L.A., Webster R.G. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine. 11:1993;957-960.
22. Fynan E.F., Robinson H.L., Webster R.G. Use of DNA encoding influenza hemagglutinin as an avian influenza vaccine. DNA Cell Biol. 12:1993;785-789.
23. Pertmer T.M., Eisenbraun M.D., McCabe D., Prayaga S.K., Fuller D.H., Haynes J.R. Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T-lymphocyte responses following epidermal delivery of nanogram quantities of DNA. Vaccine. 13:1995;1427-1430.
24. Donnelly J.J., Friedman A., Martinez D., Montgomery D.L., Shiver J.W., Motzel S.L., Ulmer J.B., Liu M.A. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. Nat. Med. 1:1995;583-587.
25. Fynan E.F., Robinson H.L., Webster R.G. Use of DNA encoding influenza hemagglutinin as an avian influenza vaccine. DNA Cell Biol. 12:1993;785-789.
26. Webster R.G., Fynan E.F., Santoro J.C., Robinson H. Protection of ferrets against influenza challenge with a DNA vaccine to the haemagglutinin. Vaccine. 12:1994;1495-1498.
27. Montgomery D.L., Shiver J.W., Leander K.R., Perry H.C., Friedman A., Martinez D., Ulmer J.B., Donnelly J.J., Liu M.A. Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors. DNA Cell Biol. 12:1993;777-783.
28. Rabinovich N.R., McInnes P., Klein D.L., Hall B.F. Vaccine technologies: view to the future. Science. 265:1994;1401-1404.
29. Oehen S., Hengartner H., Zinkernagel R.M. Vaccination for disease. Science. 251:1991;195-198.
30. Audibert F.M., Lise L.D. Adjuvants: current status, clinical perspectives and future prospects. Trends. Pharmacol. Sci. 14:1993;174-178.
31. Ulmer J.B., Donnelly J.J., Parker S.E., Rhodes G.H., Felgner P.L., Dwarki V.J., Gromkowski S.H., Deck R.R., DeWitt C.M., Friedman A.et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science. 259:1993;1745-1749.
32. Cohen J. Naked DNA points way to vaccines. Science. 259:1993;1691-1692.
33. Mor G., Singla M., Steinberg A.D., Hoffman S.L., Okuda K., Klinman D.M. Do DNA vaccines induce autoinimune disease? Hum. Gene Therapy. 8:1997;293-300.
34. Fynan E.F., Webster R.G., Fuller D.H., Haynes J.R., Santoro J.C., Robinson H.L. DNA vaccines: a novel approach to immunization. Int. J. Immunopharm. 17:1995;79-83.
35. Fynan E.F., Webster R.G., Fuller D.H., Haynes J.R., Santoro L.C., Robinson H.L. DNA vaccines: protective immunizations by parenteral, mucosal and gene-gun inoculations. Proc. Nad. Acad. Sci. 90:1993;11478-11482.
36. Raz E., Carson D.A., Parker S.E., Parr T.B., Abai A.M., Aichinger G., Gromkowski S.H., Singh M., Lew D., Yankauckas M.A.et al. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Nad. Acad Sci. 91:1994;9519-9523.
37. Fynan E.F., Webster R.G., Fuller D.H., Haynes J.R., Santoro J.C., Robinson H.L. DNA vaccines: protective immunizations by parenteral, mucosal and gene-gun inoculations. Proc. Nad. Acad. Sci. 90:1993;11478-11482.
38. Pertmer T.M., Roberts T.R., Haynes J.R. Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery. J. Virol. 70:1996;6119-6125.
39. Olsen C.W., McGregor M.W., Dybdahl-Sissoko N., Schram B.R., Nelson K.M., Lunn D.P., Macklin M.D., Swain W.F., Hinshaw V.S. Immunogenicity and efficacy of baculovirus-expressed and DNA-based equine influenza virus hemagglutinin vaccines in mice. Vaccine. 15:1997;1149-1156.
40. Tang D.C., DeVit M., Johnston S.A. Genetic immunization is a simple method for eliciting an immune response. Nature. 356:1992;152-154.
41. Hinshaw V.S., Naeve C.W., Webster R.G., Douglas A., Skehel J.J., Bryans J. Analysis of antigenic variation in equine 2 influenza A viruses. Bull. World Health. Org. 61:1983;153-158.
42. Laver W.G. Purification of influenza virus. In: Habel K., Salzman N.P., editors. Fundamental techniques in virology. New York: Academic Press, 1969. p. 82-6.
43. Palmer D.F., Dowdle W.R., Coleman M.T. Advanced laboratory techniques for influenza diagnosis. 6th ed. US Department of Health, Education and Welfare Immunology Series, 1975.
44. Lunn D.P., Holmes M.A., Antczak D.F., Baker J.M., Bendali-Ahcene S., Blanchard-Channell M., Byrne K.M., Cannizzo K., Davis W., Hamilton M.J., Hannant D., Kondo T., Kydd J.H., Monier M.C., Moore P.F., Neeraj N., Schram B.R., Sheoran A.S., Stott J.L., Sugiura T., Vagnoni K.E. Report of the Second Equine Leucocyte Antigen Workshop. Vet. Immunol. Immunopathol. 42:1998;3-60.
45. Kendal A.P., Pereira M.S., Skehel J.J. Concepts and procedures for laboratory-based influenza surveillance. US Department of Health and Human Services, 1982.
46. Macklin M.D., McCabe D.E., McGregor M.W., Neumann V., Meyer T., Callan R., Hinshaw V.S., Swain W.F. Immunization of pigs with a particle-mediated DNA vaccine to influenza A protects against challenge with homologous virus. J. Virol. 72:1998;1491-1496.
47. Bender B.S., Small P.A.J. Influenza: pathogenesis and host defense. Semin. Respir. Infect. 7:1992;38-45.
48. Renegar K.B., Small P.A.J. Immunoglobulin A mediation of murine nasal anti-influenza virus immunity. J. Virol. 65:1991;2146-2148.
49. Mostov K.E. Transepithelial transport of immunoglobulins. Annu. Rev. Immunol. 12:1994;63-84.
50. Holmgren J., Czerkinsky C., Lycke N., Svennerholm A.M. Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier and adjuvant. Am. J Trop. Med. Hyg. 50:1994;42-54.
51. Tamura S., Funato H., Hirabayashi Y., Suzuki Y., Nagamine T., Aizawa C., Kurata T. Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules. Eur. J. Immunol. 21:1991;1337-1344.
52. Mazanec M.B., Kaetzel C.S., Lamm M.E., Fletcher D., Nedrud J.G. Intracellular neutralization of virus by immunoglobulin A antibodies. Proc. Nad. Acad. Sci. 89:1992;6901-6905.
53. Underdown B.J., Mestecky J. Mucosal immunoglobulins. In: Ogra P.L., Strober W., Mestecky J., McGhee J.R., Lamm M.E., Bienenstock J., editors. Handbook of mucosal immunology. San Diego: Academic Press, Inc., 1994. p. 79-85.
54. Hannant D., Mumford J.A. Cell mediated immune responses in ponies following infection with equine influenza virus (H3N8): the influence of induction culture conditions on the properties of cytotoxic effector cells. Vet. Immunol. Immunopathol. 21:1989;327-337.
55. Rimmelzwaan G.F., Osterhaus A.D. Cytotoxic T-lymphocyte memory: role in cross-protective immunity against influenza? Vaccine. 13:1995;703-705.
56. Saikh K.U., Martin J.D., Nishikawa A.H., Dillon S.B. Influenza A virus-specific H-2d restricted cross-reactive cytotoxic T-lymphocyte epitope(s) detected in the hemagglutinin HA2 subunit of A/Udorn/72. Virology. 214:1995;445-452.
57. Ulmer J.B., Fu T.M., Deck R.R., Friedman A., Guan L., DeWitt C., Liu X., Wang S., Liu M.A., Donnelly J.J., Caulfield M.J. Protective CD4+ and CD8+ T-cells against influenza virus induced by vaccination with nucleoprotein DNA. J. Virol. 72:1998;5648-5653.
58. Fu T.M., Friedman A., Ulmer J.B., Liu M.A., Donnelly J.J. Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nueleoprotein induced by DNA immunization. J. Virol. 71:1997;2715-2721.
59. Ben Ahmeida E.T., Jennings R., Erturk M., Potter C.W. The IgA and subclass IgG responses and protection in mice immunised with influenza antigens administered as ISCOMS, with FCA, ALH or as infectious virus. Arch. Virol. 125:1992;71-86.
60. Hocart M.J., Mackenzie J.S., Stewart G.A. The IgG subclass responses induced by wild-type, cold-adapted and purified haemagglutinin from influenza virus A/Queensland/6/72 in 20 CBA/CaH mice. J. Gen. Virol. 69:1988;1873-1882.
61. Ben Ahmeida E.T., Potter C.W., Gregoriadis G., Adithan C., Jennings R. IgG subclass response and protection against challenge following immunisation of mice with various influenza A vaccines. J. Med. Microbiol. 40:1994;261-269.
62. Hocart M.J., Mackenzie J.S., Stewart G.A. The immunoglobulin G subclass responses of mice to influenza A virus: the effect of mouse strain, and the neutralizing abilities of individual protein A-purified subclass antibodies. J. Gen. Virol. 70:1989;2439-2448.
63. Hocart M.J., Mackenzie J.S., Stewart G.A. The IgG subclass responses to influenza virus haemagglutinin in the mouse: effect of route of inoculation. J. Gen. Virol. 70:1989;809-818.
64. McGuire T.C., Crawford T.B., Henson J.B. The isolation, characterisation and functional properties of equine immunoglobulin classes and subclasses. In: Bryans J.T., Gerber H., editors. Proceedings of the 3rd International Conference on Equine Infectious Diseases, Paris 1972. Basel: Karger, 1973. p. 364-381.
65. Banks K.L., McGuire T.C. Surface receptors on neutrophils and monocytes from immunodeficient and normal horses. Immunology. 28:1975;581-588.
66. Mazanec M.B., Lamm M.E., Lyn D., Portner A., Nedrud J.G. Comparison of IgA versus IgG monoclonal antibodies for passive immunization of the murine respiratory tract. Virus Res. 23:1992;1-12.
67. Lamb R.A., Krug R.M. Orthomyxoviridae: the viruses and their replication. In: Fields B.N., Knipe D.M., Howley P.M., editors. Fields Virology, vol. 1. 3rd ed. Philadelphia: Lippincott-Raven, 1996. p. 1353-96.
68. Keitel W.A., Couch R.B., Cate T.R., Hess K.R., Baxter B., Quarles J.M., Atmar R.L., Six H.R. High doses of purified influenza A virus hemagglutinin significantly augment serum and nasal secretion antibody responses in healthy young adults. J. Clin. Micro. 32:1994;2468-2472.
69. Tamura S., Funato H., Hirabayashi Y., Kikuta K., Suzuki Y., Nagamine T., Aizawa C., Nakagawa M., Kurata T. Functional role of respiratory tract haemagglutinin-specific IgA antibodies in protection against influenza. Vaccine. 8:1990;479-485.