Detection and localization of surgically resectable cancers with a multi-analyte blood test

Science

Volumn 359, Issue 6378, 2018, Pages 926-930

  Cohen, Joshua D ^a,b   Li, Lu ^c   Wang, Yuxuan ^a,b   Thoburn, Christopher ^b   Afsari, Bahman ^d   Danilova, Ludmila ^d   Douville, Christopher ^a,b   Javed, Ammar A ^d   Wong, Fay ^a,b   Mattox, Austin ^a,b   Hruban, Ralph H ^a,b,d   Wolfgang, Christopher L ^d   Goggins, Michael G ^a,b,d   Molin, Marco Dal ^a   Wang, Tian Li ^b,d   Roden, Richard ^b,d   Klein, Alison P ^a,b,c   Ptak, Janine ^a,b   Dobbyn, Lisa ^a,b   Schaefer, Joy ^a,b   Silliman, Natalie ^a,b   Popoli, Maria ^a,b   Vogelstein, Joshua T ^a   Browne, James D ^e   Schoen, Robert E ^f,g   Brand, Randall E ^f   Tie, Jeanne ^h,i,j,k   Gibbs, Peter ^h,i,j,k   Wong, Hui Li ^h   Mansfield, Aaron S ^l   Jen, Jin ^l   Hanash, Samir M ^m   Falconi, Massimo ⁿ   Allen, Peter J ^o   Zhou, Shibin ^a,b   Bettegowda, Chetan ^a,b   Diaz, Luis A ^a,b,o   Tomasetti, Cristian ^b,c,d   Kinzler, Kenneth W ^a,b   Vogelstein, Bert ^a,b   Lennon, Anne Marie ^a,b,d   Papadopoulos, Nickolas ^a,b   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d DEPARTMENT OF PATHOLOGY   (United States)

^e Johns Hopkins University   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^h WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

ⁱ UNIVERSITY OF MELBOURNE   (Australia)

^j WESTERN HEALTH   (Australia)

^k PETER MACCALLUM CANCER CENTRE   (Australia)

^l MAYO CLINIC   (United States)

^m UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

ⁿ SAN RAFFAELE HOSPITAL   (Italy)

^o MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CA 125 ANTIGEN; CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; DNA; MYELOPEROXIDASE; OSTEOPONTIN; PROLACTIN; PROTEIN; SCATTER FACTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; CIRCULATING TUMOR DNA; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BREAST CANCER; CANCER LOCALIZATION; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; EARLY CANCER DIAGNOSIS; ESOPHAGUS CANCER; FEMALE; HUMAN; LIVER CANCER; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASM; MUTATION; OVARY CANCER; PANCREAS CANCER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; STOMACH CANCER; BLOOD; BLOOD EXAMINATION; COST; ECONOMICS; EVALUATION STUDY; GENETICS; NEOPLASM; POLYMERASE CHAIN REACTION; PROCEDURES;

CIRCULATING TUMOR DNA; COSTS AND COST ANALYSIS; EARLY DETECTION OF CANCER; HEMATOLOGIC TESTS; HUMANS; MUTATION; NEOPLASM PROTEINS; NEOPLASMS; POLYMERASE CHAIN REACTION;

EID: 85040865768     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aar3247     Document Type: Article

References (30)

1. R. L. Siegel, K. D. Miller, A. Jemal, CA Cancer J. Clin. 67, 7-30 (2017).
2. B. Vogelstein et al., Science 339, 1546-1558 (2013).
3. S. Jones et al., Proc. Natl. Acad. Sci. U.S.A. 105, 4283-4288 (2008).
4. S. Yachida et al., Clin. Cancer Res. 18, 6339-6347 (2012).
5. B. Vogelstein, K. W. Kinzler, N. Engl. J. Med. 373, 1895-1898 (2015).
6. I. Bozic et al., eLife 2, e00747 (2013).
7. T. J. Semrad, A. R. Fahrni, I. Y. Gong, V. P. Khatri, Ann. Surg. Oncol. 22 (suppl. 3), S855-S862 (2015).
8. C. G. Moertel et al., Ann. Intern. Med. 122, 321-326 (1995).
9. A. C. Huang et al., Nature 545, 60-65 (2017).
10. P. F. Pinsky, P. C. Prorok, B. S. Kramer, N. Engl. J. Med. 376, 1285-1289 (2017).
11. C. Bettegowda et al., Sci. Transl. Med. 6, 224ra24 (2014).
12. D. A. Haber, V. E. Velculescu, Cancer Discov. 4, 650-661 (2014).
13. S. J. Dawson et al., N. Engl. J. Med. 368, 1199-1209 (2013).
14. Y. Wang et al., Sci. Transl. Med. 7, 293ra104 (2015).
15. T. Forshew et al., Sci. Transl. Med. 4, 136ra68 (2012).
16. C. Abbosh et al., Nature 545, 446-451 (2017).
17. E. Beddowes, S. J. Sammut, M. Gao, C. Caldas, Breast 34 (suppl. 1), S31-S35 (2017).
18. J. Phallen et al., Sci. Transl. Med. 9, eaan2415 (2017).
19. I. A. Cree et al., BMC Cancer 17, 697 (2017).
20. J. D. Cohen et al., Proc. Natl. Acad. Sci. U.S.A. 114, 10202-10207 (2017).
21. A. Bardelli, K. Pantel, Cancer Cell 31, 172-179 (2017).
22. F. Diehl et al., Proc. Natl. Acad. Sci. U.S.A. 102, 16368-16373 (2005).
23. S. A. Forbes et al., Nucleic Acids Res. 45 (D1), D777-D783 (2017).
24. I. Kinde, J. Wu, N. Papadopoulos, K. W. Kinzler, B. Vogelstein, Proc. Natl. Acad. Sci. U.S.A. 108, 9530-9535 (2011).
25. L. A. Liotta, E. F. Petricoin 3rd, Clin. Adv. Hematol. Oncol. 1, 460-462 (2003).
26. H. Wang et al., Expert Rev. Proteomics 13, 99-114 (2016).
27. E. F. Patz Jr. et al., J. Clin. Oncol. 25, 5578-5583 (2007).
28. World Health Organization, Treatment of Tuberculosis: Guidelines (World Health Organization, 2010).
29. World Health Organization, Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach (World Health Organization, 2016).
30. A. B. Benson 3rd et al., J. Natl. Compr. Canc. Netw. 15, 370-398 (2017).