Why Social Relationships Are Important for Physical Health: A Systems Approach to Understanding and Modifying Risk and Protection

Annual Review of Psychology

Volumn 69, Issue , 2018, Pages 437-458

  Holt Lunstad, Julianne ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Loneliness; Social connection; Social ecological model; Social isolation; Social network; Social relationships

Indexed keywords

HEALTH STATUS; HUMAN; HUMAN RELATION; LONELINESS; RISK FACTOR; SOCIAL BEHAVIOR; SOCIAL ENVIRONMENT; SOCIAL ISOLATION; SOCIAL SUPPORT;

HEALTH STATUS; HUMANS; INTERPERSONAL RELATIONS; LONELINESS; RISK FACTORS; SOCIAL BEHAVIOR; SOCIAL ENVIRONMENT; SOCIAL ISOLATION; SOCIAL SUPPORT;

EID: 85040355539     PISSN: 00664308     EISSN: 15452085     Source Type: Book Series    
DOI: 10.1146/annurev-psych-122216-011902     Document Type: Review

References (122)

1. AARP. 2012. The United States of Aging survey. Rep., AARP, Washington, DC. http://www.aarp.org/ content/dam/aarp/livable-communities/learn/research/the-united-states-of-aging-survey-2012-aarp.pdf
2. Asendorpf JB, van Aken MAG. 2003. Personality-relationship transaction in adolescence: core versus surface personality characteristics. J. Personal. 71:629-66
3. Appleton AA, Holdsworth E, Ryan M, Tracy M. 2016. Measuring childhood adversity in life course cardiovascular research: a systematic review. Psychosom. Med. 79(4):434-40
4. Ball K, Jeffery RW, Abbott G, McNaughton SA, Crawford D. 2010. Is healthy behavior contagious: associations of social norms with physical activity and healthy eating. Int. J. Behav. Nutr. Phys. Act. 7:86
5. Bates DW, Saria S, Ohno-Machado L, Shah A, Escobar G. 2014. Big data in health care: using analytics to identify and manage high-risk and high-cost patients. Health Aff. 33:1123-31
6. Baum S, Kendall E, Parekh S. 2016. Self-assessed health status and neighborhood context. J. Prev. Interv. Community 44:283-95
7. Beauchamp G. 2014. Social Predation: How Group Living Helps Predators and Prey. Amsterdam: Elsevier
8. Beckes L, Coan JA, Hasselmo K. 2013. Familiarity promotes the blurring of self and other in the neural representation of threat. Soc. Cogn. Affect. Neurosci. 8:670-77
9. Berkowitz AD. 2004. An overview of the social norms approach. In Changing the Culture of College Drinking, ed. L Lederman, L Stewart, pp. 193-214. Cresskill, NJ: Hampton Press
10. Berry D, McCartney K, Petrill S, Deater-Deckard K, Blair C. 2014. Gene-environment interaction between DRD4 7-repeat VNTR and early child-care experiences predicts self-regulation abilities in prekindergarten. Dev. Psychobiol. 56:373-91
11. Berscheid E, Reis HT. 1998. Attraction and close relationships. In The Handbook of Social Psychology, Vol. 2, ed. DT Gilbert, ST Fiske, G Lindzey, pp. 193-281. New York: McGraw-Hill. 4th ed.
12. Berwick DM. 1989. Continuous improvement as an ideal in health care. N. Engl. J. Med. 320:53-56
13. Black C, Collen B, JohnstonD, Hart T. 2016. Why huddle? Ecological drivers of chick aggregations in gentoo penguins, Pygoscelis papua, across latitudes. PLOS ONE 11:e0145676
14. Bliss CA, Kloumann IM, Harris KD, Danforth CM, Dodds PS. 2011. Twitter reciprocal reply networks exhibit assortativity with respect to happiness. arXiv:1112.1010 [cs.SI]
15. Boesen EH, Johansen C. 2008. Impact of psychotherapy on cancer survival: time to move on? Curr. Opin. Oncol. 20:372-77
16. Bowlby J. 1969. Attachment and Loss: Volume Attachment. New York: Basic Books
17. Cacioppo JT, Cacioppo S, Boomsma DI. 2014. Evolutionary mechanisms for loneliness. Cogn. Emot. 28:3-21
18. Cacioppo S, Grippo AJ, London S, Goossens L, Cacioppo JT. 2015. Loneliness: clinical import and interventions. Perspect. Psychol. Sci. 10:238-49
19. Cacioppo JT, Hawley LC, Ernst JM, Burlson M, Berntson GG, et al. 2006. Loneliness within a nomological net: an evolutionary perspective. J. Res. Personal. 40:1054-85
20. CDC (Cent. Dis. Control). 2015. The social-ecological model: a framework for prevention. Rep., Div. Violence Prev., Nat. Cent. Inj. Prev. Control, Cent. Dis. Control, Atlanta, GA. https://www.cdc.gov/ violenceprevention/overview/social-ecologicalmodel.html
21. CDC (Cent. Dis. Control Prev.). 2016. Cigarette smoking among adults-United States, 2005-2015. Morb. Mortal. Wkly. Rep. 65(44):1205-11
22. Chen YR, Schulz PJ. 2016. The effect of information communication technology interventions on reducing social isolation in the elderly: a systematic review. J. Med. Internet Res. 18:e18
23. Christakis NA, Fowler JH. 2007. The spread of obesity in a large social network over 32 years. N. Engl. J. Med. 357:370-79
24. Christakis NA, Fowler JH. 2008. The collective dynamics of smoking in a large social network. N. Engl. J. Med. 358:2249-58
25. Christakis NA, Fowler JH. 2013. Social contagion theory: examining dynamic social networks and human behavior. Stat. Med. 32:556-77
26. Coan JA, Sbarra DA. 2015. Social baseline theory: the social regulation of risk and effort. Curr. Opin. Psychol. 1:87-91
27. Coan JA, Schaefer HS, Davidson RJ. 2006. Lending a hand: social regulation of the neural response to threat. Psychol. Sci. 17:1032-39
28. Craddock E, vanDellen MR, Novak SA, Ranby KW. 2015. Influence in relationships: a meta-analysis on health-related social control. Basic Appl. Soc. Psychol. 37(2):118-30
29. Craske MG, Stein MB. 2016. Anxiety. Lancet 388:3048-59
30. Cummings KM, Proctor RN. 2014. The changing public image of smoking in the United States: 1964-2014. Cancer Epidemiol. Biomark. Prev. 23(1):32-36
31. Derrick JL, Leonard KE, Homish GG. 2013. Perceived partner responsiveness predicts decreases in smoking during the first nine years of marriage. Nicotine Tob. Res. 15:1528-36
32. Diamond LM, Hicks AM. 2004. Psychobiological perspectives on attachment: implications for health over the lifespan. In Adult Attachment: Theory, Research, and Clinical Implications, ed. WS Rholes, JA Simpson, pp. 240-263. New York: Guilford Press
33. Dickens AP, Richards SH, Hawton A, Taylor RS, Greaves CJ, et al. 2011. An evaluation of the effectiveness of a community mentoring service for socially isolated older people: a controlled trial. BMC Public Health 11:218
34. Dietz WH, Gortmaker SL. 2016. New strategies to prioritize nutrition, physical activity, and obesity interventions. Am. J. Prev. Med. 51(5):e145-50
35. Ditzen B, HeinrichsM. 2014. Psychobiology of social support: the social dimension of stress buffering. Restor. Neurol. Neurosci. 32:149-62
36. Ebbeling CB, Pawlak DB, Ludwig DS. 2002. Childhood obesity: public-health crisis, common sense cure. Lancet 360:473-82
37. EisenbergerNI. 2012. The pain of social disconnection: examining the shared neural underpinnings of physical and social pain. Nat. Rev. Neurosci. 13:421-34
38. EisenbergerNI, LiebermanMD, WilliamsKD. 2003. Does rejection hurt? An FMRI study of social exclusion. Science 302:290-92
39. Eisenberger NI, Moieni M, Inagaki TK, Muscatell KA, Irwin MR. 2017. In sickness and in health: the coregulation of inflammation and social behavior. Neuropsychopharmacology 42:242-53
40. Fagundes CP, Bennett JM, Derry HM, Kiecolt-Glaser JK. 2011. Relationships and inflammation across the lifespan: social developmental pathways to disease. Soc. Personal. Psychol. Compass 5:891-903
41. Fitzsimons GM, Finkel EM. 2010. Interpersonal influences on self-regulation. Curr. Dir. Psychol. Sci. 19:101-5
42. Fitzsimons GM, vanDellenMR. 2015. Goal pursuit in close relationships. In Handbook of Personality and Social Psychology: Interpersonal Relations and Group Processes, ed. JA Simpson, JF Dovidio, pp. 273-96. Washington, DC: Am. Psychol. Assoc.
43. Flegal KM, Kit BK, Orpana H, Graubard BI. 2013. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 309:71-82
44. Franck L, Molyneux N, Parkinson L. 2016. Systematic review of interventions addressing social isolation and depression in aged care clients. Qual. Life Res. 25:1395-407
45. Gardiner C, Geldenhuys G, Gott M. 2017. Interventions to reduce social isolation and loneliness among older people: an integrative review. Health Soc. Care Community. In press
46. Han S, Ma Y. 2014. Cultural differences in human brain activity: a quantitative meta-analysis. NeuroImage 99:293-300
47. Hatzenbuehler ML, Flores JE, Cavanaugh JE, Onwuachi-Willig A, RamirezMR. 2017. Anti-bullying policies and disparities in bullying: a state-level analysis. Am. J. Prev. Med. 53(2):184-91
48. Hawkley LC, Capitanio JP. 2015. Perceived social isolation, evolutionary fitness and health outcomes: a lifespan approach. Philos. Trans. R. Soc. Lond. B 370(1669):20140114
49. Hennessy MB, Kaiser S, Sachser N. 2009. Social buffering of the stress response: diversity, mechanisms, and functions. Front. Neuroendocrinol. 30:470-82
50. Hogan BE, Linden W, Najarian B. 2002. Social support interventions: Do they work? Clin. Psychol. Rev. 22:383-442
51. Holt-Lunstad J, Robles T, Sbarra D. 2017. Advancing social connection as a public health priority. Am. Psychol. 72(6):517-30
52. Holt-Lunstad J, Smith TB, Baker M, Harris T, Stephenson D. 2015. Loneliness and social isolation as risk factors for mortality: a meta-analytic review. Perspect. Psychol. Sci. 10:227-37
53. Holt-Lunstad J, Smith TB, Layton JB. 2010. Social relationships and mortality risk: a meta-analytic review. PLOS Med. 7:e1000316
54. Hostinar CE. 2015. Recent developments in the study of social relationships, stress responses, and physical health. Curr. Opin. Psychol. 5:90-95
55. Hostinar CE, Gunnar MR. 2015. Social support can buffer against stress and shape brain activity. AJOB Neurosci. 6:34-42
56. House JS, Landis KR, Umberson D. 1988. Social relationships and health. Science 241:540-45
57. Inst. Med. 2003. Who Will Keep the Public Healthy? Educating Public Health Professionals for the 21st Century. Washington, DC: Natl. Acad. Press
58. Ioannou CC, Guttal V, Couzin ID. 2012. Predatory fish select for coordinated collective motion in virtual prey. Science 337:1212-15
59. Kim DA, Benjamin EJ, Fowler JH, Christakis NA. 2016. Social connectedness is associated with fibrinogen level in a human social network. Proc. Biol. Sci. 283(1837):20160958
60. Kim DA, Hwong AR, Stafford D, Hughes DA, O'Malley AJ, et al. 2015. Social network targeting to maximise population behaviour change: a cluster randomised controlled trial. Lancet 386:145-53
61. Kissane D, Li Y. 2008. Effects of supportive-expressive group therapy on survival of patients with metastatic breast cancer: a randomized prospective trial. Cancer 112:443-44
62. Kraemer HC, Kazdin AE, Offord DR, Kessler RC, Jensen PS, Kupfer DJ. 1997. Coming to terms with the terms of risk. Arch. Gen. Psychiatry 54(4):337-43
63. Lacey RE, Kumari M, Bartley M. 2014. Social isolation in childhood and adult inflammation: evidence from the National Child Development Study. Psychoneuroendocrinology 50:85-94
64. Lacey RE, Kumari M, McMunn A. 2013. Parental separation in childhood and adult inflammation: the importance of material and psychosocial pathways. Psychoneuroendocrinology 38:2476-84
65. Lau S, Gruen GE. 1992. The social stigma of loneliness: effect of target person's and perceiver's sex. Personal. Soc. Psychol. Bull. 18(2):182-89
66. Lee S, Kim CJ, Kim DH. 2015. A meta-analysis of the effect of school-based anti-bullying programs. J. Child Health Care 19:136-53
67. Lemery-Chalfant K, Kao K, Swann G, Goldsmith HH. 2013. Childhood temperament: passive geneenvironment correlation, gene-environment interaction, and the hidden importance of the family environment. Dev. Psychopathol. 25:51-63
68. Lewis MA, Rook KS. 1999. Social control in personal relationships: impact on health behaviors and psychological distress. Health Psychol. 18:63-71
69. Lombard CB, Deeks AA, Teede HJ. 2009. A systematic review of interventions aimed at the prevention of weight gain in adults. Public Health Nutr. 12(11):2236-46
70. Loseth GE, EllingsenDM, Leknes S. 2014. State-dependent μ-opioidmodulation of social motivation. Front. Behav. Neurosci. 8:430
71. Lovely C, Rampersad M, Fernandes Y, Eberhart J. 2017. Gene-environment interactions in development and disease. Wiley Interdiscip. Rev. Dev. Biol. 6:e247
72. Machin AJ, Dunbar R. 2011. The brain opioid theory of social attachment: a review of the evidence. Behavior 148:985-1025
73. Malambo P, Kengne AP, De Villiers A, Lambert EV, Puoane T. 2016. Built environment, selected risk factors and major cardiovascular disease outcomes: a systematic review. PLOS ONE 11:e0166846
74. Manzoli L, Villari P, Pirone GM, Boccia A. 2007. Marital status and mortality in the elderly: a systematic review and meta-analysis. Soc. Sci. Med. 64:77-94
75. MartireLM, Schulz R, Helgeson VS, Small BJ, SaghafiEM. 2010. Review andmeta-analysis of couple-oriented interventions for chronic illness. Ann. Behav. Med. 40:325-42
76. Masi CM, Chen HY, Hawkley LC, Cacioppo JT. 2011. A meta-analysis of interventions to reduce loneliness. Personal. Soc. Psychol. Rev. 15:219-66
77. McLaughlin KA, SheridanMA, LambertHK. 2014. Childhood adversity and neural development: deprivation and threat as distinct dimensions of early experience. Neurosci. Biobehav. Rev. 47:578-91
78. McPherson M, Smith-Lovin L, Brashears ME. 2006. Social isolation in America: changes in core discussion networks over two decades. Am. Sociol. Rev. 71(3):353-75
79. Mead N, Lester H, Chew-Graham C, Gask L, Bower P. 2010. Effects of befriending on depressive symptoms and distress: systematic review and meta-analysis. Br. J. Psychiatry 196:96-101
80. MikulincerM, Shaver PR. 2007. Attachment in Adulthood: Structure, Dynamics, and Change.NewYork:Guilford Press
81. Mitchell C, McLanahan S, Brooks-Gunn J, Garfinkel I, Hobcraft J, Notterman D. 2013. Genetic differential sensitivity to social environments: implications for research. Am. J. Public Health 103(Suppl. 1): S102-10
82. Oishi S, Saeki M, Axt J. 2015. Are people living in walkable areas healthier and more satisfied with life? Appl. Psychol. Health Well-Being 7:365-86
83. Oliveira BS, Zunzunegui MV, Quinlan J, Fahmi H, Tu MT, Guerra RO. 2016. Systematic review of the association between chronic social stress and telomere length: a life course perspective. Ageing Res. Rev. 26:37-52
84. Parascandola M, Weed DL. 2001. Causation in epidemiology. J. Epidemiol. Community Health 55:905-12
85. Parascandola M, Weed DL, Dasgupta A. 2006. Two Surgeon General's reports on smoking and cancer: a historical investigation of the practice of causal inference. Emerg. Themes Epidemiol. 3:1
86. Pays O, BeauchampG, Carter AJ, Goldizen AW. 2013. Foraging in groups allows collective predator detection in a mammal species without alarm calls. Behav. Ecol. 24(5):1229-36
87. Perissinotto CM, Stijacic Cenzer I, Covinsky KE. 2012. Loneliness in older persons: a predictor of functional decline and death. Arch. Intern. Med. 172(14):1078-83
88. Pew Res. Cent. 2009. Social isolation and new technology. Pew Research Center, Nov. 4
89. Pew Res. Cent. 2015. US Smartphone use in 2015. Pew Research Center, April 1
90. Pietromonaco PR, Uchino B, Dunkel Schetter C. 2013. Close relationship processes and health: implications of attachment theory for health and disease. Health Psychol. 32:499-513
91. Plotnikoff RC, Costigan SA, Williams RL, Hutchesson MJ, Kennedy SG, et al. 2015. Effectiveness of interventions targeting physical activity, nutrition and healthy weight for university and college students: a systematic review and meta-analysis. Int. J. Behav. Nutr. Phys. Act. 12:45
92. Portacolone E, Perissinotto C, Yeh JC, Greysen SR. 2017. "I feel trapped": the tension between personal and structural factors of social isolation and the desire for social integration among older residents of a high-crime neighborhood. Gerontologist. In press
93. Pressman SD, Cohen S, Miller GE, Barkin A, Rabin BS, Treanor JJ. 2005. Loneliness, social network size, and immune response to influenza vaccination in college freshmen. Health Psychol. 24:297-306
94. Reis HT, Collins AW, Berschied E. 2000. The relationship context of human behavior and development. Psychol. Bull. 126:844-72
95. Robles TF, Kane HS. 2014. The attachment system and physiology in adulthood: normative processes, individual differences, and implications for health. J. Personal. 82:515-27
96. Robles TF, Kiecolt-Glaser JK. 2003. The physiology ofmarriage: pathways to health. Physiol. Behav. 79:409-16
97. Robles TF, Slatcher RB, Trombello JM, McGinn MM. 2014. Marital quality and health: a meta-analytic review. Psychol. Bull. 140:140-87
98. Roelfs DJ, Shor E, Kalish R, Yogev T. 2011. The rising relative risk of mortality for singles: meta-analysis and meta-regression. Am. J. Epidemiol. 174:379-89
99. Rook KS. 2009. Gaps in social support resources in later life: an adaptational challenge in need of further research. J. Soc. Pers. Relatsh. 26(1):103-12
100. Ross HE, Young LJ. 2009. Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Front. Neuroendocrinol. 30:534-47
101. Saito T, Kai I, Takizawa A. 2012. Effects of a program to prevent social isolation on loneliness, depression, and subjective well-being of older adults: a randomized trial among older migrants in Japan. Arch. Gerontol. Geriatr. 55:539-47
102. Sbarra DA, Law RW, Portley RM. 2011. Divorce and death: a meta-analysis and research agenda for clinical, social, and health psychology. Perspect. Psychol. Sci. 6:454-74
103. Schultz PW, Nolan JM, Cialdini RB, Goldstein NJ, Griskevicius V. 2007. The constructive, destructive, and reconstructive power of social norms. Psychol. Sci. 18:429-34
104. Shor E, Roelfs DJ. 2015. Social contact frequency and all-cause mortality: ameta-analysis and meta-regression. Soc. Sci. Med. 128:76-86
105. Shor E, Roelfs DJ, Bugyi P, Schwartz JE. 2012a. Meta-analysis of marital dissolution and mortality: reevaluating the intersection of gender and age. Soc. Sci. Med. 75:46-59
106. Shor E, Roelfs DJ, Curreli M, Clemow L, Burg MM, Schwartz JE. 2012b. Widowhood and mortality: a meta-analysis and meta-regression. Demography 49:575-606
107. Shor E, Roelfs DJ, Yogev T. 2013. The strength of family ties: a meta-analysis and meta-regression of selfreported social support and mortality. Soc. Netw. 35:626-38
108. Slatcher RB, Selcuk E, Ong AD. 2015. Perceived partner responsiveness predicts diurnal cortisol profiles 10 years later. Psychol. Sci. 26:972-82
109. Slavich GM, Irwin MR. 2014. From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol. Bull. 140:774-815
110. Spiegel D, Bloom JR, Kraemer HC, Gottheil E. 1989. Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet 2:888-91
111. Stampfer MJ, Ridker PM, Dzau VJ. 2004. Risk factor criteria. Circulation 109:IV3-5
112. Tanskanen J, Anttila T. 2016. A prospective study of social isolation, loneliness, and mortality in Finland. Am. J. Public Health 106:2042-48
113. Templeton EM, Stanton MV, Zaki J. 2016. Social norms shift preferences for healthy and unhealthy foods. PLOS ONE 11:e0166286
114. Uchino BN. 2006. Social support and health: a review of physiological processes potentially underlying links to disease outcomes. J. Behav. Med. 29:377-87
115. Uchino BN. 2009. What a lifespan approach might tell us about why distinct measures of social support have differential links to physical health. J. Soc. Personal. Relatsh. 26:53-62
116. US Dep. Health Hum. Serv. 2014. The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon General. Atlanta, GA: US Dep. Health Hum. Serv.
117. Vella EJ, Kamarck TW, Shiffman S. 2008. Hostility moderates the effects of social support and intimacy on blood pressure in daily social interactions. Health Psychol. 27: S155-62
118. Vespa J, Lewis JM, Kreider RM. 2013. America's families and living arrangements: 2012. Curr. Pop. Rep. P20-570, US Census Bur., Washington, DC
119. Vetere A. 1987. General system theory and the family: a critical evaluation. In Ecological Studies of Family Life, ed. A Vetere, A Gale, pp. 18-33. Chichester, UK:Wiley
120. Way BM, Lieberman MD. 2010. Is there a genetic contribution to cultural differences? Collectivism, individualism and genetic markers of social sensitivity. Soc. Cogn. Affect. Neurosci. 5:203-11
121. WenM, Cagney KA, Christakis NA. 2005. Effect of specific aspects of community social environment on the mortality of individuals diagnosed with serious illness. Soc. Sci. Med. 61:1119-34
122. Yang YC, Boen C, Gerken K, Li T, Schorpp K, Harris KM. 2016. Social relationships and physiological determinants of longevity across the human life span. PNAS 113(3):578-83