Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Lucas, Sébastien ^a   Omata, Yasunori ^a   Hofmann, Jörg ^b   Böttcher, Martin ^a   Iljazovic, Aida ^c   Sarter, Kerstin ^a   Albrecht, Olivia ^a   Schulz, Oscar ^a   Krishnacoumar, Brenda ^a   Krönke, Gerhard ^a   Herrmann, Martin ^a   Mougiakakos, Dimitrios ^a   Strowig, Till ^c   Schett, Georg ^a   Zaiss, Mario M ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; BUTYRIC ACID; FATTY ACID; GAMMA INTERFERON; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; NFATC1 PROTEIN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROPIONATE SODIUM; PROPIONIC ACID; PROTEIN; RAG1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; BUTYRIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE; PROTECTIVE AGENT; VOLATILE FATTY ACID;

BONE; CHEMICAL COMPOUND; CHEMICAL REACTION; DIFFERENTIATION; FATTY ACID; FERMENTATION; GENE; GENE EXPRESSION; HOMEOSTASIS; IMMUNE RESPONSE; IMMUNE SYSTEM; INHIBITION; METABOLISM; METABOLITE; MICROBIAL ACTIVITY; OXIDATIVE STRESS; PATHOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MASS; BONE METABOLISM; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE SEVERITY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL ARTHRITIS; FEMALE; GLYCOLYSIS; HIGH FIBER DIET; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INHIBITION KINETICS; INTESTINE FLORA; MOUSE; NONHUMAN; NORMAL HUMAN; NUCLEAR REPROGRAMMING; OSSIFICATION; OSTEOCLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; OSTEOLYSIS; OXIDATIVE PHOSPHORYLATION; POSTMENOPAUSE; PRIMARY PREVENTION; REGULATORY T LYMPHOCYTE; ADMINISTRATION AND DOSAGE; ANIMAL; BONE; BONE DENSITY; C57BL MOUSE; DIETARY FIBER; DRUG EFFECTS; GENE EXPRESSION; METABOLISM; PREVENTION AND CONTROL;

MUS;

ANIMALS; BONE AND BONES; BONE DENSITY; BONE RESORPTION; BUTYRATES; DIETARY FIBER; FATTY ACIDS, VOLATILE; FEMALE; GENE EXPRESSION; GLYCOLYSIS; HUMANS; MICE, INBRED C57BL; OSTEOCLASTS; PROPIONATES; PROTECTIVE AGENTS;

EID: 85040220188     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02490-4     Document Type: Article

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