메뉴 건너뛰기




Volumn 131, Issue 1, 2018, Pages 13-29

CD38 antibodies in multiple myeloma: Back to the future

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CANCER ANTIBODY; CD38 ANTIBODY; FC RECEPTOR; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG; ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; CD38 PROTEIN, HUMAN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

EID: 85040045284     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2017-06-740944     Document Type: Review
Times cited : (352)

References (106)
  • 1
    • 84930319546 scopus 로고    scopus 로고
    • CD38-targeted immunochemotherapy in refractory multiple myeloma: A new horizon
    • Laubach JP, Richardson PG. CD38-targeted immunochemotherapy in refractory multiple myeloma: a new horizon. Clin Cancer Res. 2015;21(12):2660-2662.
    • (2015) Clin Cancer Res. , vol.21 , Issue.12 , pp. 2660-2662
    • Laubach, J.P.1    Richardson, P.G.2
  • 2
    • 0040226744 scopus 로고
    • Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage
    • Reinherz EL, Kung PC, Goldstein G, Levey RH, Schlossman SF. Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage. Proc Natl Acad Sci USA. 1980;77(3): 1588-1592.
    • (1980) Proc Natl Acad Sci USA , vol.77 , Issue.3 , pp. 1588-1592
    • Reinherz, E.L.1    Kung, P.C.2    Goldstein, G.3    Levey, R.H.4    Schlossman, S.F.5
  • 3
    • 0019426166 scopus 로고
    • Biochemical studies of the human thymocyte cell-surface antigens T6, T9 and T10
    • Terhorst C, van Agthoven A, LeClair K, Snow P, Reinherz E, Schlossman S. Biochemical studies of the human thymocyte cell-surface antigens T6, T9 and T10. Cell. 1981;23(3): 771-780.
    • (1981) Cell , vol.23 , Issue.3 , pp. 771-780
    • Terhorst, C.1    Van Agthoven, A.2    LeClair, K.3    Snow, P.4    Reinherz, E.5    Schlossman, S.6
  • 4
    • 0035177850 scopus 로고    scopus 로고
    • Human CD38: A (r)evolutionary story of enzymes and receptors
    • Deaglio S, Mehta K, Malavasi F. Human CD38: a (r)evolutionary story of enzymes and receptors. Leuk Res. 2001;25(1):1-12.
    • (2001) Leuk Res. , vol.25 , Issue.1 , pp. 1-12
    • Deaglio, S.1    Mehta, K.2    Malavasi, F.3
  • 5
    • 84979519854 scopus 로고    scopus 로고
    • Daratumumab depletes CD381 immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma
    • Krejcik J, Casneuf T, Nijhof IS, et al. Daratumumab depletes CD381 immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma. Blood. 2016;128(3):384-394.
    • (2016) Blood , vol.128 , Issue.3 , pp. 384-394
    • Krejcik, J.1    Casneuf, T.2    Nijhof, I.S.3
  • 6
    • 85032898279 scopus 로고    scopus 로고
    • Functional evidence that progenitor cells near sites of inflammation are precursors for aggressive prostate cancer
    • Crowell PD, Goldstein AS. Functional evidence that progenitor cells near sites of inflammation are precursors for aggressive prostate cancer. Mol Cell Oncol. 2017;4(2): e1279723.
    • (2017) Mol Cell Oncol. , vol.4 , Issue.2 , pp. e1279723
    • Crowell, P.D.1    Goldstein, A.S.2
  • 7
    • 4043174779 scopus 로고    scopus 로고
    • Methodologic advancements in the study of airway smooth muscle
    • Kotlikoff MI, Kannan MS, Solway J, et al. Methodologic advancements in the study of airway smooth muscle. J Allergy Clin Immunol. 2004;114(suppl 2):S18-S31.
    • (2004) J Allergy Clin Immunol. , vol.114 , pp. S18-S31
    • Kotlikoff, M.I.1    Kannan, M.S.2    Solway, J.3
  • 8
    • 64549160176 scopus 로고    scopus 로고
    • CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus
    • Horenstein AL, Sizzano F, Lusso R, et al. CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. Mol Med. 2009;15(3-4):76-84.
    • (2009) Mol Med. , vol.15 , Issue.3-4 , pp. 76-84
    • Horenstein, A.L.1    Sizzano, F.2    Lusso, R.3
  • 9
    • 84871697250 scopus 로고    scopus 로고
    • NAADP mediates insulin-stimulated glucose uptake and insulin sensitization by PPARg in adipocytes
    • Song EK, Lee YR, Kim YR, et al. NAADP mediates insulin-stimulated glucose uptake and insulin sensitization by PPARg in adipocytes. Cell Reports. 2012;2(6):1607-1619.
    • (2012) Cell Reports , vol.2 , Issue.6 , pp. 1607-1619
    • Song, E.K.1    Lee, Y.R.2    Kim, Y.R.3
  • 10
    • 0025299903 scopus 로고
    • CD38 molecule: Structural and biochemical analysis on human T lymphocytes, thymocytes, and plasma cells
    • Alessio M, Roggero S, Funaro A, et al. CD38 molecule: structural and biochemical analysis on human T lymphocytes, thymocytes, and plasma cells. J Immunol. 1990;145(3): 878-884.
    • (1990) J Immunol. , vol.145 , Issue.3 , pp. 878-884
    • Alessio, M.1    Roggero, S.2    Funaro, A.3
  • 11
    • 50349083286 scopus 로고    scopus 로고
    • Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
    • Malavasi F, Deaglio S, Funaro A, et al. Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology. Physiol Rev. 2008;88(3):841-886.
    • (2008) Physiol Rev. , vol.88 , Issue.3 , pp. 841-886
    • Malavasi, F.1    Deaglio, S.2    Funaro, A.3
  • 12
    • 0031930758 scopus 로고    scopus 로고
    • Human CD38 (ADP-ribosyl cyclase) is a counterreceptor of CD31, an Ig superfamily member
    • Deaglio S, Morra M, Mallone R, et al. Human CD38 (ADP-ribosyl cyclase) is a counterreceptor of CD31, an Ig superfamily member. J Immunol. 1998;160(1):395-402.
    • (1998) J Immunol. , vol.160 , Issue.1 , pp. 395-402
    • Deaglio, S.1    Morra, M.2    Mallone, R.3
  • 13
    • 42749096451 scopus 로고    scopus 로고
    • Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse
    • Muñoz P, Mittelbrunn M, de la Fuente H, et al. Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse. Blood. 2008; 111(7):3653-3664.
    • (2008) Blood , vol.111 , Issue.7 , pp. 3653-3664
    • Muñoz, P.1    Mittelbrunn, M.2    De La Fuente, H.3
  • 14
    • 0027763586 scopus 로고
    • Formation and hydrolysis of cyclic ADPribose catalyzed by lymphocyte antigen CD38
    • Howard M, Grimaldi JC, Bazan JF, et al. Formation and hydrolysis of cyclic ADPribose catalyzed by lymphocyte antigen CD38. Science. 1993;262(5136):1056-1059.
    • (1993) Science , vol.262 , Issue.5136 , pp. 1056-1059
    • Howard, M.1    Grimaldi, J.C.2    Bazan, J.F.3
  • 15
    • 26644460215 scopus 로고    scopus 로고
    • Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling
    • Lee HC. Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling. J Biol Chem. 2005;280(40): 33693-33696.
    • (2005) J Biol Chem. , vol.280 , Issue.40 , pp. 33693-33696
    • Lee, H.C.1
  • 16
    • 84887151819 scopus 로고    scopus 로고
    • Intracellular NAD1 depletion enhances bortezomib-induced anti-myeloma activity
    • Cagnetta A, Cea M, Calimeri T, et al. Intracellular NAD1 depletion enhances bortezomib-induced anti-myeloma activity. Blood. 2013;122(7):1243-1255.
    • (2013) Blood , vol.122 , Issue.7 , pp. 1243-1255
    • Cagnetta, A.1    Cea, M.2    Calimeri, T.3
  • 18
    • 0025980998 scopus 로고
    • Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody
    • Stevenson FK, Bell AJ, Cusack R, et al. Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody. Blood. 1991;77(5):1071-1079.
    • (1991) Blood , vol.77 , Issue.5 , pp. 1071-1079
    • Stevenson, F.K.1    Bell, A.J.2    Cusack, R.3
  • 19
    • 0027987119 scopus 로고
    • Anti-CD38-blocked ricin: An immunotoxin for the treatment of multiple myeloma
    • Goldmacher VS, Bourret LA, Levine BA, et al. Anti-CD38-blocked ricin: an immunotoxin for the treatment of multiple myeloma. Blood. 1994;84(9):3017-3025.
    • (1994) Blood , vol.84 , Issue.9 , pp. 3017-3025
    • Goldmacher, V.S.1    Bourret, L.A.2    Levine, B.A.3
  • 20
    • 79251570884 scopus 로고    scopus 로고
    • Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
    • de Weers M, Tai YT, van der Veer MS, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol. 2011;186(3): 1840-1848.
    • (2011) J Immunol. , vol.186 , Issue.3 , pp. 1840-1848
    • De Weers, M.1    Tai, Y.T.2    Van Der Veer, M.S.3
  • 21
    • 84924546237 scopus 로고    scopus 로고
    • Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
    • Overdijk MB, Verploegen S, Bögels M, et al. Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma. MAbs. 2015;7(2): 311-321.
    • (2015) MAbs , vol.7 , Issue.2 , pp. 311-321
    • Overdijk, M.B.1    Verploegen, S.2    Bögels, M.3
  • 22
    • 84979518325 scopus 로고    scopus 로고
    • The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcg receptor-mediated cross-linking
    • Overdijk MB, Jansen JH, Nederend M, et al. The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcg receptor-mediated cross-linking. J Immunol. 2016;197(3):807-813.
    • (2016) J Immunol. , vol.197 , Issue.3 , pp. 807-813
    • Overdijk, M.B.1    Jansen, J.H.2    Nederend, M.3
  • 23
    • 84947031216 scopus 로고    scopus 로고
    • Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087, SAR650984 and Ab79 [abstract]
    • Abstract 3474
    • Lammerts van Bueren J, Jakobs D, Kaldenhoven N, et al. Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087, SAR650984 and Ab79 [abstract]. Blood. 2014;124(21). Abstract 3474.
    • (2014) Blood , vol.124 , Issue.21
    • Lammerts Van Bueren, J.1    Jakobs, D.2    Kaldenhoven, N.3
  • 24
    • 84912126930 scopus 로고    scopus 로고
    • SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD381 hematologic malignancies
    • Deckert J, Wetzel MC, Bartle LM, et al. SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD381 hematologic malignancies. Clin Cancer Res. 2014;20(17): 4574-4583.
    • (2014) Clin Cancer Res. , vol.20 , Issue.17 , pp. 4574-4583
    • Deckert, J.1    Wetzel, M.C.2    Bartle, L.M.3
  • 25
    • 84959362725 scopus 로고    scopus 로고
    • SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide
    • Jiang H, Acharya C, An G, et al. SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide. Leukemia. 2016;30(2): 399-408.
    • (2016) Leukemia , vol.30 , Issue.2 , pp. 399-408
    • Jiang, H.1    Acharya, C.2    An, G.3
  • 26
    • 85014708569 scopus 로고    scopus 로고
    • High-parameter mass cytometry (CyTOF) evaluation of relapsed/refractory multiple myeloma (MM) Pts (Pts) treated with daratumumab supports immune modulation as a novel mechanism of action [abstract]
    • Abstract 4521
    • Adams H III, Stevenaert F, Krejcik J, et al. High-parameter mass cytometry (CyTOF) evaluation of relapsed/refractory multiple myeloma (MM) Pts (Pts) treated with daratumumab supports immune modulation as a novel mechanism of action [abstract]. Blood. 2016;128(22). Abstract 4521.
    • (2016) Blood , vol.128 , Issue.22
    • Adams, H.1    Stevenaert, F.2    Krejcik, J.3
  • 27
    • 85023639305 scopus 로고    scopus 로고
    • Targeting CD38 suppresses induction and function of T regulatory cells to mitigate immunosuppression in multiple myeloma
    • Feng X, Zhang L, Acharya C, et al. Targeting CD38 suppresses induction and function of T regulatory cells to mitigate immunosuppression in multiple myeloma. Clin Cancer Res. 2017;23(15):4290-4300.
    • (2017) Clin Cancer Res. , vol.23 , Issue.15 , pp. 4290-4300
    • Feng, X.1    Zhang, L.2    Acharya, C.3
  • 28
    • 85022338705 scopus 로고    scopus 로고
    • Daratumumab monotherapy compared with historical control data in heavily pretreated and highly refractory patients with multiple myeloma: An adjusted treatment comparison
    • Usmani SZ, Diels J, Ito T, Mehra M, Khan I, Lam A. Daratumumab monotherapy compared with historical control data in heavily pretreated and highly refractory patients with multiple myeloma: an adjusted treatment comparison. Am J Hematol. 2017; 92(8):E146-E152.
    • (2017) Am J Hematol. , vol.92 , Issue.8 , pp. E146-E152
    • Usmani, S.Z.1    Diels, J.2    Ito, T.3    Mehra, M.4    Khan, I.5    Lam, A.6
  • 29
    • 84942436321 scopus 로고    scopus 로고
    • Targeting CD38 with daratumumab monotherapy in multiple myeloma
    • Lokhorst HM, Plesner T, Laubach JP, et al. Targeting CD38 with daratumumab monotherapy in multiple myeloma. N Engl J Med. 2015;373(13):1207-1219.
    • (2015) N Engl J Med. , vol.373 , Issue.13 , pp. 1207-1219
    • Lokhorst, H.M.1    Plesner, T.2    Laubach, J.P.3
  • 30
    • 84953325096 scopus 로고    scopus 로고
    • Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): An open-label, randomised, phase 2 trial
    • (10027)
    • Lonial S, Weiss BM, Usmani SZ, et al. Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial. Lancet. 2016;387(10027):1551-1560.
    • (2016) Lancet , vol.387 , pp. 1551-1560
    • Lonial, S.1    Weiss, B.M.2    Usmani, S.Z.3
  • 31
    • 84977616350 scopus 로고    scopus 로고
    • Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma
    • Usmani SZ, Weiss BM, Plesner T, et al. Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma. Blood. 2016;128(1):37-44.
    • (2016) Blood , vol.128 , Issue.1 , pp. 37-44
    • Usmani, S.Z.1    Weiss, B.M.2    Plesner, T.3
  • 32
    • 84941342711 scopus 로고    scopus 로고
    • Preclinical evidence for the therapeutic potential of CD38-targeted immunochemotherapy in multiple myeloma patients refractory to lenalidomide and bortezomib
    • Nijhof IS, Groen RW, Noort WA, et al. Preclinical evidence for the therapeutic potential of CD38-targeted immunochemotherapy in multiple myeloma patients refractory to lenalidomide and bortezomib. Clin Cancer Res. 2015;21(12):2802-2810.
    • (2015) Clin Cancer Res. , vol.21 , Issue.12 , pp. 2802-2810
    • Nijhof, I.S.1    Groen, R.W.2    Noort, W.A.3
  • 33
    • 84997822677 scopus 로고    scopus 로고
    • Pharmacokinetics of daratumumab following intravenous infusion in relapsed or refractory multiple myeloma after prior proteasome inhibitor and immunomodulatory drug treatment
    • Clemens PL, Yan X, Lokhorst HM, et al. Pharmacokinetics of daratumumab following intravenous infusion in relapsed or refractory multiple myeloma after prior proteasome inhibitor and immunomodulatory drug treatment. Clin Pharmacokinet. 2017;56(8): 915-924.
    • (2017) Clin Pharmacokinet. , vol.56 , Issue.8 , pp. 915-924
    • Clemens, P.L.1    Yan, X.2    Lokhorst, H.M.3
  • 34
    • 85013018486 scopus 로고    scopus 로고
    • Clinical implications of complex pharmacokinetics for daratumumab dose regimen in patients with relapsed/refractory multiple myeloma
    • Xu XS, Yan X, Puchalski T, et al. Clinical implications of complex pharmacokinetics for daratumumab dose regimen in patients with relapsed/refractory multiple myeloma. Clin Pharmacol Ther. 2017;101(6):721-724.
    • (2017) Clin Pharmacol Ther. , vol.101 , Issue.6 , pp. 721-724
    • Xu, X.S.1    Yan, X.2    Puchalski, T.3
  • 35
    • 85020076875 scopus 로고    scopus 로고
    • Openlabel, multicenter, dose escalation phase 1b study to assess the subcutaneous delivery of daratumumab in patients (pts) with relapsed or refractory multiple myeloma (PAVO) [abstract]
    • Abstract 1149
    • Usmani S, Nahi H, Mateos MV, et al. Openlabel, multicenter, dose escalation phase 1b study to assess the subcutaneous delivery of daratumumab in patients (pts) with relapsed or refractory multiple myeloma (PAVO) [abstract]. Blood. 2016;128(22). Abstract 1149.
    • (2016) Blood , vol.128 , Issue.22
    • Usmani, S.1    Nahi, H.2    Mateos, M.V.3
  • 36
    • 85020070587 scopus 로고    scopus 로고
    • A phase I/IIa study of the CD38 antibody MOR202 alone and in combination with pomalidomide or lenalidomide in patients with relapsed or refractory multiple myeloma [abstract]
    • Abstract 1152
    • Raab M, Chatterjee M, Goldschmidt H, et al. A phase I/IIa study of the CD38 antibody MOR202 alone and in combination with pomalidomide or lenalidomide in patients with relapsed or refractory multiple myeloma [abstract]. Blood. 2016;128(22). Abstract 1152.
    • (2016) Blood , vol.128 , Issue.22
    • Raab, M.1    Chatterjee, M.2    Goldschmidt, H.3
  • 37
    • 84989848538 scopus 로고    scopus 로고
    • A dose finding phase II trial of isatuximab (SAR650984, anti-CD38 mAb) as a single agent in relapsed/refractory multiple myeloma [abstract]
    • Abstract 509
    • Martin TG III, Richter J, Vij R, Cole C, Atanackovic D, Zonder J. A dose finding phase II trial of isatuximab (SAR650984, anti-CD38 mAb) as a single agent in relapsed/refractory multiple myeloma [abstract]. Blood. 2015;126(23). Abstract 509.
    • (2015) Blood , vol.126 , Issue.23
    • Martin, T.G.1    Richter, J.2    Vij, R.3    Cole, C.4    Atanackovic, D.5    Zonder, J.6
  • 38
    • 85014111853 scopus 로고    scopus 로고
    • Updated data from a phase II dose finding trial of single agent isatuximab (SAR650984, anti-CD38 mAb) in relapsed/refractory multiple myeloma (RRMM) [abstract]
    • Richter J, Martin TG III, Vij R, et al. Updated data from a phase II dose finding trial of single agent isatuximab (SAR650984, anti-CD38 mAb) in relapsed/refractory multiple myeloma (RRMM) [abstract]. J Clin Oncol. 2016;34(suppl 15):8005.
    • (2016) J Clin Oncol. , vol.34 , pp. 8005
    • Richter, J.1    Martin, T.G.2    Vij, R.3
  • 39
    • 84943587393 scopus 로고    scopus 로고
    • Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab
    • Nijhof IS, Groen RW, Lokhorst HM, et al. Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab. Leukemia. 2015;29(10):2039-2049.
    • (2015) Leukemia , vol.29 , Issue.10 , pp. 2039-2049
    • Nijhof, I.S.1    Groen, R.W.2    Lokhorst, H.M.3
  • 40
    • 84986905126 scopus 로고    scopus 로고
    • CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
    • Nijhof IS, Casneuf T, van Velzen J, et al. CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma. Blood. 2016;128(7):959-970.
    • (2016) Blood , vol.128 , Issue.7 , pp. 959-970
    • Nijhof, I.S.1    Casneuf, T.2    Van Velzen, J.3
  • 41
    • 84886437588 scopus 로고    scopus 로고
    • Accessory cells of the microenvironment protect multiple myeloma from T-cell cytotoxicity through cell adhesion-mediated immune resistance
    • de Haart SJ, van de Donk NW, Minnema MC, et al. Accessory cells of the microenvironment protect multiple myeloma from T-cell cytotoxicity through cell adhesion-mediated immune resistance. Clin Cancer Res. 2013; 19(20):5591-5601.
    • (2013) Clin Cancer Res. , vol.19 , Issue.20 , pp. 5591-5601
    • De Haart, S.J.1    Van De Donk, N.W.2    Minnema, M.C.3
  • 42
    • 84980378067 scopus 로고    scopus 로고
    • Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance
    • de Haart SJ, Holthof L, Noort WA, et al. Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance. Haematologica. 2016;101(8): e339-e342.
    • (2016) Haematologica , vol.101 , Issue.8 , pp. e339-e342
    • De Haart, S.J.1    Holthof, L.2    Noort, W.A.3
  • 43
    • 84957664777 scopus 로고    scopus 로고
    • KIR and HLA genotypes influence clinical outcome in multiple myeloma patients treated with SAR650984 (anti-CD38) in combination with lenalidomide and dexamethasone [abstract]
    • Abstract 2126
    • Marra J, Du J, Hwang J, Wolf J, Martin TG III, Venstrom J. KIR and HLA genotypes influence clinical outcome in multiple myeloma patients treated with SAR650984 (anti-CD38) in combination with lenalidomide and dexamethasone [abstract]. Blood. 2014; 124(21). Abstract 2126.
    • (2014) Blood , vol.124 , Issue.21
    • Marra, J.1    Du, J.2    Hwang, J.3    Wolf, J.4    Martin, T.G.5    Venstrom, J.6
  • 44
    • 84973577130 scopus 로고    scopus 로고
    • NAD1-metabolizing ectoenzymes in remodeling tumor-host interactions: The human myeloma model
    • Horenstein AL, Chillemi A, Quarona V, et al. NAD1-metabolizing ectoenzymes in remodeling tumor-host interactions: the human myeloma model. Cells. 2015;4(3): 520-537.
    • (2015) Cells , vol.4 , Issue.3 , pp. 520-537
    • Horenstein, A.L.1    Chillemi, A.2    Quarona, V.3
  • 45
    • 84947045446 scopus 로고    scopus 로고
    • SAR 650984, a therapeutic anti-CD38 monoclonal antibody, blocks CD38-CD31 interaction in multiple myeloma [abstract]
    • Abstract 4729
    • An G, Jiang H, Acharya C, et al. SAR 650984, a therapeutic anti-CD38 monoclonal antibody, blocks CD38-CD31 interaction in multiple myeloma [abstract]. Blood. 2014; 124(21). Abstract 4729.
    • (2014) Blood , vol.124 , Issue.21
    • An, G.1    Jiang, H.2    Acharya, C.3
  • 46
    • 85038586706 scopus 로고    scopus 로고
    • Generation and characterization of microvesicles after daratumumab interaction with myeloma cells [abstract]
    • Abstract 1849
    • Chillemi A, Quarona V, Zito A, et al. Generation and characterization of microvesicles after daratumumab interaction with myeloma cells [abstract]. Blood. 2015;126(23). Abstract 1849.
    • (2015) Blood , vol.126 , Issue.23
    • Chillemi, A.1    Quarona, V.2    Zito, A.3
  • 47
    • 84921745242 scopus 로고    scopus 로고
    • Fcg-receptormediated trogocytosis impacts mAb-based therapies: Historical precedence and recent developments
    • Taylor RP, Lindorfer MA. Fcg-receptormediated trogocytosis impacts mAb-based therapies: historical precedence and recent developments. Blood. 2015;125(5):762-766.
    • (2015) Blood , vol.125 , Issue.5 , pp. 762-766
    • Taylor, R.P.1    Lindorfer, M.A.2
  • 48
    • 84984680198 scopus 로고    scopus 로고
    • Daratumumab, bortezomib, and dexamethasone for multiple myeloma
    • Palumbo A, Chanan-Khan A, Weisel K, et al; CASTOR Investigators. Daratumumab, bortezomib, and dexamethasone for multiple myeloma. N Engl J Med. 2016;375(8): 754-766.
    • (2016) N Engl J Med. , vol.375 , Issue.8 , pp. 754-766
    • Palumbo, A.1    Chanan-Khan, A.2    Weisel, K.3
  • 49
    • 84905453261 scopus 로고    scopus 로고
    • SAR650984, a CD38 monoclonal antibody in patients with selected CD381 hematological malignancies: Data from a dose-escalation phase I study [abstract]
    • Martin T, Strickland S, Glenn M, Zheng W, Daskalakis N, Mikhael J. SAR650984, a CD38 monoclonal antibody in patients with selected CD381 hematological malignancies: data from a dose-escalation phase I study [abstract]. Blood. 2013;122(21):284.
    • (2013) Blood , vol.122 , Issue.21 , pp. 284
    • Martin, T.1    Strickland, S.2    Glenn, M.3    Zheng, W.4    Daskalakis, N.5    Mikhael, J.6
  • 50
    • 84969375698 scopus 로고    scopus 로고
    • A phase I/IIa study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma (rrMM) [abstract]
    • Raab M, Goldschmidt H, Agis H, Blau I, Einsele H, Engelhardt M. A phase I/IIa study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma (rrMM) [abstract]. J Clin Oncol. 2015;33(suppl):8574.
    • (2015) J Clin Oncol. , vol.33 , pp. 8574
    • Raab, M.1    Goldschmidt, H.2    Agis, H.3    Blau, I.4    Einsele, H.5    Engelhardt, M.6
  • 51
    • 85034016063 scopus 로고    scopus 로고
    • Treatment of ex vivo expanded NK cells with daratumumab F(ab') 2 fragments protects adoptively transferred NK cells from daratumumab-mediated killing and augments daratumumab-induced antibody dependent cellular toxicity (ADCC) of myeloma [abstract]
    • Abstract 4244
    • Cherkasova E, Espinoza L, Kotecha R, Reger R, Berg M, Aue G. Treatment of ex vivo expanded NK cells with daratumumab F(ab') 2 fragments protects adoptively transferred NK cells from daratumumab-mediated killing and augments daratumumab-induced antibody dependent cellular toxicity (ADCC) of myeloma [abstract]. Blood. 2015;126(23). Abstract 4244.
    • (2015) Blood , vol.126 , Issue.23
    • Cherkasova, E.1    Espinoza, L.2    Kotecha, R.3    Reger, R.4    Berg, M.5    Aue, G.6
  • 52
    • 85038590918 scopus 로고    scopus 로고
    • Pharmacodynamic relationship between natural killer cells and daratumumab exposure in relapsed/refractory multiple myeloma [abstract]
    • 10 June Copenhagen, Denmark. Abstract P286
    • Casneuf T, Xu X, Adams H, et al. Pharmacodynamic relationship between natural killer cells and daratumumab exposure in relapsed/refractory multiple myeloma [abstract]. In: Proceedings from the EHA21 Congress; 10 June 2016; Copenhagen, Denmark. Abstract P286.
    • (2016) Proceedings from the EHA21 Congress
    • Casneuf, T.1    Xu, X.2    Adams, H.3
  • 53
    • 84979279948 scopus 로고    scopus 로고
    • Rechallenging with anti-CD38 monotherapy in triple-refractory multiple myeloma patients is a feasible and safe approach
    • Alici E, Chrobok M, Lund J, et al. Rechallenging with anti-CD38 monotherapy in triple-refractory multiple myeloma patients is a feasible and safe approach. Br J Haematol. 2016;174(3):473-477.
    • (2016) Br J Haematol. , vol.174 , Issue.3 , pp. 473-477
    • Alici, E.1    Chrobok, M.2    Lund, J.3
  • 54
    • 84864061825 scopus 로고    scopus 로고
    • The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies
    • van der Veer MS, de Weers M, van Kessel B, et al. The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies. Blood Cancer J. 2011;1(10):e41.
    • (2011) Blood Cancer J. , vol.1 , Issue.10 , pp. e41
    • Van Der Veer, M.S.1    De Weers, M.2    Van Kessel, B.3
  • 55
    • 79251581902 scopus 로고    scopus 로고
    • Towards effective immunotherapy of myeloma: Enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab
    • van der Veer MS, de Weers M, van Kessel B, et al. Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab. Haematologica. 2011;96(2): 284-290.
    • (2011) Haematologica , vol.96 , Issue.2 , pp. 284-290
    • Van Der Veer, M.S.1    De Weers, M.2    Van Kessel, B.3
  • 56
    • 84999034131 scopus 로고    scopus 로고
    • Effect of IMiD compounds on CD38 expression on multiple myeloma cells: MOR202, a human CD38 antibody in combination with pomalidomide [abstract]
    • Boxhammer R, Steidl S, Endell J. Effect of IMiD compounds on CD38 expression on multiple myeloma cells: MOR202, a human CD38 antibody in combination with pomalidomide [abstract]. J Clin Oncol. 2015;33(suppl 15):8588.
    • (2015) J Clin Oncol. , vol.33 , pp. 8588
    • Boxhammer, R.1    Steidl, S.2    Endell, J.3
  • 57
    • 84998531186 scopus 로고    scopus 로고
    • Synergistic in vitro activity of MOR202, a human CD38 antibody, in combination with pomalidomide [abstract]
    • Abstract 5712
    • Endell J, Boxhammer R, Steidl S. Synergistic in vitro activity of MOR202, a human CD38 antibody, in combination with pomalidomide [abstract]. Blood. 2014;124(21). Abstract 5712.
    • (2014) Blood , vol.124 , Issue.21
    • Endell, J.1    Boxhammer, R.2    Steidl, S.3
  • 58
    • 85055211523 scopus 로고    scopus 로고
    • Lenalidomide enhances MOR202 dependent macrophage-mediated effector functions via the vitamin D pathway [abstract]
    • Abstract 2203
    • Bruns H, Jitschin R, Mougiakakos D, et al. Lenalidomide enhances MOR202 dependent macrophage-mediated effector functions via the vitamin D pathway [abstract]. Blood. 2015;126(23). Abstract 2203.
    • (2015) Blood , vol.126 , Issue.23
    • Bruns, H.1    Jitschin, R.2    Mougiakakos, D.3
  • 59
    • 84990046018 scopus 로고    scopus 로고
    • Daratumumab, lenalidomide, and dexamethasone for multiple myeloma
    • Dimopoulos MA, Oriol A, Nahi H, et al; POLLUX Investigators. Daratumumab, lenalidomide, and dexamethasone for multiple myeloma. N Engl J Med. 2016;375(14): 1319-1331.
    • (2016) N Engl J Med. , vol.375 , Issue.14 , pp. 1319-1331
    • Dimopoulos, M.A.1    Oriol, A.2    Nahi, H.3
  • 60
    • 85015385618 scopus 로고    scopus 로고
    • Efficacy of daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma patients with 1 to 3 prior lines of therapy: Updated analysis of Pollux [abstract]
    • Abstract 1151
    • Usmani S, Dimopoulos M, Belch A, et al. Efficacy of daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma patients with 1 to 3 prior lines of therapy: updated analysis of Pollux [abstract]. Blood. 2016;128(22). Abstract 1151.
    • (2016) Blood , vol.128 , Issue.22
    • Usmani, S.1    Dimopoulos, M.2    Belch, A.3
  • 61
    • 85020137642 scopus 로고    scopus 로고
    • Evaluation of minimal residual disease (MRD) in relapsed/refractory multiple myeloma (RRMM) patients treated with daratumumab in combination with lenalidomide plus dexamethasone or bortezomib plus dexamethasone [abstract]
    • Abstract 246
    • Avet-Loiseau H, Casneuf T, Chiu C, et al. Evaluation of minimal residual disease (MRD) in relapsed/refractory multiple myeloma (RRMM) patients treated with daratumumab in combination with lenalidomide plus dexamethasone or bortezomib plus dexamethasone [abstract]. Blood. 2016; 128(22). Abstract 246.
    • (2016) Blood , vol.128 , Issue.22
    • Avet-Loiseau, H.1    Casneuf, T.2    Chiu, C.3
  • 62
    • 85040074160 scopus 로고    scopus 로고
    • Depth of response and MRD with daratumumab plus lenalidomide and dexamethasone (DRd) vs lenalidomide and dexamethasone (Rd) in RRMM: Pollux [abstract]
    • San-Miguel J, Dimopoulos MA, Usmani S, et al. Depth of response and MRD with daratumumab plus lenalidomide and dexamethasone (DRd) vs lenalidomide and dexamethasone (Rd) in RRMM: Pollux [abstract]. Clin Lymphoma Myeloma Leuk. 2017; 17(suppl 1):e17-e18.
    • (2017) Clin Lymphoma Myeloma Leuk. , vol.17 , pp. e17-e18
    • San-Miguel, J.1    Dimopoulos, M.A.2    Usmani, S.3
  • 63
    • 85020474499 scopus 로고    scopus 로고
    • Daratumumab in combination with lenalidomide plus dexamethasone induces clonality increase and T-cell expansion: Results from a phase 3 randomized study (POLLUX) [abstract]
    • Abstract 4531
    • Chiu C, Casneuf T, Axel A, et al. Daratumumab in combination with lenalidomide plus dexamethasone induces clonality increase and T-cell expansion: results from a phase 3 randomized study (POLLUX) [abstract]. Blood. 2016;128(22). Abstract 4531.
    • (2016) Blood , vol.128 , Issue.22
    • Chiu, C.1    Casneuf, T.2    Axel, A.3
  • 64
    • 85021632881 scopus 로고    scopus 로고
    • A phase 1b study of isatuximab plus lenalidomide and dexamethasone for relapsed/refractory multiple myeloma
    • Martin T, Baz R, Benson DM, et al. A phase 1b study of isatuximab plus lenalidomide and dexamethasone for relapsed/refractory multiple myeloma. Blood. 2017;129(25): 3294-3303.
    • (2017) Blood , vol.129 , Issue.25 , pp. 3294-3303
    • Martin, T.1    Baz, R.2    Benson, D.M.3
  • 65
    • 85054895810 scopus 로고    scopus 로고
    • A phase I/IIa study of the CD38 antibody MOR202 in combination with pomalidomide or lenalidomide in patients with relapsed or refractory multiple myeloma [abstract]
    • Chatterjee M, Raab MS, Goldschmidt H, et al. A phase I/IIa study of the CD38 antibody MOR202 in combination with pomalidomide or lenalidomide in patients with relapsed or refractory multiple myeloma [abstract]. Clin Lymphoma Myeloma Leuk. 2017;17(suppl 1):e61.
    • (2017) Clin Lymphoma Myeloma Leuk. , vol.17 , pp. e61
    • Chatterjee, M.1    Raab, M.S.2    Goldschmidt, H.3
  • 66
    • 85054894485 scopus 로고    scopus 로고
    • Phase 1b study of daratumumab plus pomalidomide and dexamethasone in relapsed and/or refractory multiple myeloma (RRMM) with$2 prior lines of therapy [abstract]
    • Chari A, Suvannasankha A, Fay J, et al. Phase 1b study of daratumumab plus pomalidomide and dexamethasone in relapsed and/or refractory multiple myeloma (RRMM) with$2 prior lines of therapy [abstract]. Clin Lymphoma Myeloma Leuk. 2017;17(suppl 1): e14-e15.
    • (2017) Clin Lymphoma Myeloma Leuk. , vol.17 , pp. e14-e15
    • Chari, A.1    Suvannasankha, A.2    Fay, J.3
  • 67
    • 85020101041 scopus 로고    scopus 로고
    • Preliminary results from a phase Ib study of isatuximab in combination with pomalidomide and dexamethasone in relapsed and refractory multiple myeloma [abstract]
    • Richardson P, Mikhael J, Usmani S, Raje N, Bensinger W, Campana F. Preliminary results from a phase Ib study of isatuximab in combination with pomalidomide and dexamethasone in relapsed and refractory multiple myeloma [abstract]. Blood. 2016; 128(22):2123.
    • (2016) Blood , vol.128 , Issue.22 , pp. 2123
    • Richardson, P.1    Mikhael, J.2    Usmani, S.3    Raje, N.4    Bensinger, W.5    Campana, F.6
  • 68
    • 85020121891 scopus 로고    scopus 로고
    • Critical analysis on the mechanism of action (MoA) of the anti-CD38 monoclonal antibody isatuximab in multiple myeloma (MM) [abstract]
    • Moreno L, Zabaleta A, Alignani D, et al. Critical analysis on the mechanism of action (MoA) of the anti-CD38 monoclonal antibody isatuximab in multiple myeloma (MM) [abstract]. Blood. 2016;128(22):2105.
    • (2016) Blood , vol.128 , Issue.22 , pp. 2105
    • Moreno, L.1    Zabaleta, A.2    Alignani, D.3
  • 69
    • 85040027090 scopus 로고    scopus 로고
    • MOR202, a human anti-CD38 monoclonal antibody, mediates potent tumoricidal activity in vivo and shows synergistic efficacy in combination with different antineoplastic compounds [abstract]
    • Boxhammer R, Weirather J, Steidl C, Endell J. MOR202, a human anti-CD38 monoclonal antibody, mediates potent tumoricidal activity in vivo and shows synergistic efficacy in combination with different antineoplastic compounds [abstract]. Blood. 2015;126(23): 3015.
    • (2015) Blood , vol.126 , Issue.23 , pp. 3015
    • Boxhammer, R.1    Weirather, J.2    Steidl, C.3    Endell, J.4
  • 70
    • 85015403420 scopus 로고    scopus 로고
    • Efficacy of daratumumab, bortezomib, and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory myeloma based on prior lines of therapy: Updated analysis of castor [abstract]
    • Mateos MV, Estell J, Barreto W, et al. Efficacy of daratumumab, bortezomib, and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory myeloma based on prior lines of therapy: updated analysis of castor [abstract]. Blood. 2016;128(22):1150.
    • (2016) Blood , vol.128 , Issue.22 , pp. 1150
    • Mateos, M.V.1    Estell, J.2    Barreto, W.3
  • 71
    • 85040040545 scopus 로고    scopus 로고
    • Efficacy of daratumumab in combination with lenalidomide plus dexamethasone (DRd) or bortezomib plus dexamethasone (DVd) in relapsed or refractory multiple myeloma (RRMM) based on cytogenetic risk status [abstract]
    • Weisel KC, San Miguel J, Cook G, et al. Efficacy of daratumumab in combination with lenalidomide plus dexamethasone (DRd) or bortezomib plus dexamethasone (DVd) in relapsed or refractory multiple myeloma (RRMM) based on cytogenetic risk status [abstract]. J Clin Oncol. 2017;35(suppl 15): 8006.
    • (2017) J Clin Oncol. , vol.35 , pp. 8006
    • Weisel, K.C.1    San Miguel, J.2    Cook, G.3
  • 72
    • 85013282459 scopus 로고    scopus 로고
    • Phase Ib study of isatuximab and carfilzomib in relapse and refractory multiple myeloma [abstract]
    • Martin TG III, Mannis G, Chari A, Munster P, Campana F, Hui A. Phase Ib study of isatuximab and carfilzomib in relapse and refractory multiple myeloma [abstract]. Blood. 2016;128(22):2111.
    • (2016) Blood , vol.128 , Issue.22 , pp. 2111
    • Martin, T.G.1    Mannis, G.2    Chari, A.3    Munster, P.4    Campana, F.5    Hui, A.6
  • 73
    • 85040040232 scopus 로고    scopus 로고
    • Daratumumab (DARA) in combination with carfilzomib, lenalidomide, and dexamethasone (KRd) in patients (pts) with newly diagnosed multiple myeloma (MMY1001): An open-label, phase 1b study [abstract]
    • Jakubowiak AJ, Chari A, Lonial S, et al. Daratumumab (DARA) in combination with carfilzomib, lenalidomide, and dexamethasone (KRd) in patients (pts) with newly diagnosed multiple myeloma (MMY1001): an open-label, phase 1b study [abstract]. J Clin Oncol. 2017;35(suppl 15):8000.
    • (2017) J Clin Oncol. , vol.35 , pp. 8000
    • Jakubowiak, A.J.1    Chari, A.2    Lonial, S.3
  • 74
    • 85021677507 scopus 로고    scopus 로고
    • Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab
    • Garćia-Guerrero E, Gogishvili T, Danhof S, et al. Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab. Blood. 2017;129(25): 3386-3388.
    • (2017) Blood , vol.129 , Issue.25 , pp. 3386-3388
    • Garćia-Guerrero, E.1    Gogishvili, T.2    Danhof, S.3
  • 75
    • 84964255580 scopus 로고    scopus 로고
    • Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide
    • Nijhof IS, Lammerts van Bueren JJ, van Kessel B, et al. Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide. Haematologica. 2015;100(2):263-268.
    • (2015) Haematologica , vol.100 , Issue.2 , pp. 263-268
    • Nijhof, I.S.1    Lammerts Van Bueren, J.J.2    Van Kessel, B.3
  • 76
    • 67650646082 scopus 로고    scopus 로고
    • CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis
    • Jaiswal S, Jamieson CH, Pang WW, et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell. 2009;138(2): 271-285.
    • (2009) Cell , vol.138 , Issue.2 , pp. 271-285
    • Jaiswal, S.1    Jamieson, C.H.2    Pang, W.W.3
  • 77
    • 85038562395 scopus 로고    scopus 로고
    • CD38 as a novel immune checkpoint and a mechanism of resistance to the blockade of the PD-1/PD-L1 axis [abstract]
    • Abstract 79
    • Chen L, Averett Byers L, Ullrich S, Wistuba I, Qin X, Gibbons D. CD38 as a novel immune checkpoint and a mechanism of resistance to the blockade of the PD-1/PD-L1 axis [abstract]. J Clin Oncol. 2017;35(suppl 7S). Abstract 79.
    • (2017) J Clin Oncol. , vol.35
    • Chen, L.1    Averett Byers, L.2    Ullrich, S.3    Wistuba, I.4    Qin, X.5    Gibbons, D.6
  • 78
    • 84959423326 scopus 로고    scopus 로고
    • Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma
    • van de Donk NW, Moreau P, Plesner T, et al. Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma. Blood. 2016; 127(6):681-695.
    • (2016) Blood , vol.127 , Issue.6 , pp. 681-695
    • Van De Donk, N.W.1    Moreau, P.2    Plesner, T.3
  • 79
    • 84971352122 scopus 로고    scopus 로고
    • Management of infusion-related reactions following daratumumab monotherapy in patients with at least 3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002 (Sirius) [abstract]
    • Voorhees PM, Weiss B, Usmani S, et al. Management of infusion-related reactions following daratumumab monotherapy in patients with at least 3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002 (Sirius) [abstract]. Blood. 2015;126(23):1829.
    • (2015) Blood , vol.126 , Issue.23 , pp. 1829
    • Voorhees, P.M.1    Weiss, B.2    Usmani, S.3
  • 80
    • 85020474268 scopus 로고    scopus 로고
    • Use of montelukast to reduce infusion reactions in an early access treatment protocol of daratumumab in United States patients with relapsed or refractory multiple myeloma [abstract]
    • Chari A, Mark T, Krishnan A, et al. Use of montelukast to reduce infusion reactions in an early access treatment protocol of daratumumab in United States patients with relapsed or refractory multiple myeloma [abstract]. Blood. 2016;128(22):2142.
    • (2016) Blood , vol.128 , Issue.22 , pp. 2142
    • Chari, A.1    Mark, T.2    Krishnan, A.3
  • 81
    • 84969776462 scopus 로고    scopus 로고
    • Interference of daratumumab in monitoring multiple myeloma patients using serum immunofixation electrophoresis can be abrogated using the daratumumab IFE reflex assay (DIRA)
    • van de Donk NW, Otten HG, El Haddad O, et al. Interference of daratumumab in monitoring multiple myeloma patients using serum immunofixation electrophoresis can be abrogated using the daratumumab IFE reflex assay (DIRA). Clin Chem Lab Med. 2016; 54(6):1105-1109.
    • (2016) Clin Chem Lab Med. , vol.54 , Issue.6 , pp. 1105-1109
    • Van De Donk, N.W.1    Otten, H.G.2    El Haddad, O.3
  • 82
    • 84969835048 scopus 로고    scopus 로고
    • Monitoring multiple myeloma patients treated with daratumumab: Teasing out monoclonal antibody interference
    • McCudden C, Axel AE, Slaets D, et al. Monitoring multiple myeloma patients treated with daratumumab: teasing out monoclonal antibody interference. Clin Chem Lab Med. 2016;54(6):1095-1104.
    • (2016) Clin Chem Lab Med. , vol.54 , Issue.6 , pp. 1095-1104
    • McCudden, C.1    Axel, A.E.2    Slaets, D.3
  • 83
    • 84992034885 scopus 로고    scopus 로고
    • Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay
    • Rosenberg AS, Bainbridge S, Pahwa R, Jialal I. Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay. Clin Biochem. 2016;49(15):1202-1204.
    • (2016) Clin Biochem. , vol.49 , Issue.15 , pp. 1202-1204
    • Rosenberg, A.S.1    Bainbridge, S.2    Pahwa, R.3    Jialal, I.4
  • 84
    • 84951569958 scopus 로고    scopus 로고
    • Clarification of the definition of complete response in multiple myeloma
    • Durie BG, Miguel JF, Blade J, Rajkumar SV. Clarification of the definition of complete response in multiple myeloma. Leukemia. 2015;29(12):2416-2417.
    • (2015) Leukemia , vol.29 , Issue.12 , pp. 2416-2417
    • Durie, B.G.1    Miguel, J.F.2    Blade, J.3    Rajkumar, S.V.4
  • 85
    • 85020451994 scopus 로고    scopus 로고
    • Overcoming the interference of daratumumab with immunofixation electrophoresis (IFE) using an industry-developed Dira test: Hydrashift 2/4 daratumumab [abstract]
    • Caillon H, Irimia A, Simon J, et al. Overcoming the interference of daratumumab with immunofixation electrophoresis (IFE) using an industry-developed Dira test: hydrashift 2/4 daratumumab [abstract]. Blood. 2016;128(22):2063.
    • (2016) Blood , vol.128 , Issue.22 , pp. 2063
    • Caillon, H.1    Irimia, A.2    Simon, J.3
  • 86
    • 84995768430 scopus 로고    scopus 로고
    • Treatment of multiple myeloma with monoclonal antibodies and the dilemma of false positive M-spikes in peripheral blood
    • [published online ahead of print 21 September 2016]
    • Murata K, McCash SI, Carroll B, et al. Treatment of multiple myeloma with monoclonal antibodies and the dilemma of false positive M-spikes in peripheral blood [published online ahead of print 21 September 2016]. Clin Biochem. doi:10.1016/j.clinbiochem.2016.09.015.
    • Clin Biochem.
    • Murata, K.1    McCash, S.I.2    Carroll, B.3
  • 87
    • 84987788894 scopus 로고    scopus 로고
    • International validation of a dithiothreitol (DTT)-based method to resolve the daratumumab interference with blood compatibility testing
    • Chapuy CI, Aguad MD, Nicholson RT, et al; DARA-DTT Study Group for the BEST Collaborative. International validation of a dithiothreitol (DTT)-based method to resolve the daratumumab interference with blood compatibility testing. Transfusion. 2016; 56(12):2964-2972.
    • (2016) Transfusion , vol.56 , Issue.12 , pp. 2964-2972
    • Chapuy, C.I.1    Aguad, M.D.2    Nicholson, R.T.3
  • 88
    • 84931577511 scopus 로고    scopus 로고
    • Resolving the daratumumab interference with blood compatibility testing
    • Chapuy CI, Nicholson RT, Aguad MD, et al. Resolving the daratumumab interference with blood compatibility testing. Transfusion. 2015;55(6 Pt 2):1545-1554.
    • (2015) Transfusion , vol.55 , Issue.6 , pp. 1545-1554
    • Chapuy, C.I.1    Nicholson, R.T.2    Aguad, M.D.3
  • 89
    • 84931563891 scopus 로고    scopus 로고
    • When blood transfusion medicine becomes complicated due to interference by monoclonal antibody therapy
    • Oostendorp M, Lammerts van Bueren JJ, Doshi P, et al. When blood transfusion medicine becomes complicated due to interference by monoclonal antibody therapy. Transfusion. 2015;55(6 Pt 2):1555-1562.
    • (2015) Transfusion , vol.55 , Issue.6 , pp. 1555-1562
    • Oostendorp, M.1    Lammerts Van Bueren, J.J.2    Doshi, P.3
  • 90
    • 85020282608 scopus 로고    scopus 로고
    • Daratumumab (anti-CD38) induces loss of CD38 on red blood cells
    • Sullivan HC, Gerner-Smidt C, Nooka AK, et al. Daratumumab (anti-CD38) induces loss of CD38 on red blood cells. Blood. 2017; 129(22):3033-3037.
    • (2017) Blood , vol.129 , Issue.22 , pp. 3033-3037
    • Sullivan, H.C.1    Gerner-Smidt, C.2    Nooka, A.K.3
  • 91
    • 85021854606 scopus 로고    scopus 로고
    • Use of standard laboratory methods to obviate routine dithiothreitol treatment of blood samples with daratumumab interference
    • Lintel NJ, Brown DK, Schafer DT, Tsimba-Chitsva FM, Koepsell SA, Shunkwiler SM. Use of standard laboratory methods to obviate routine dithiothreitol treatment of blood samples with daratumumab interference. Immunohematology. 2017;33(1):22-26.
    • (2017) Immunohematology , vol.33 , Issue.1 , pp. 22-26
    • Lintel, N.J.1    Brown, D.K.2    Schafer, D.T.3    Tsimba-Chitsva, F.M.4    Koepsell, S.A.5    Shunkwiler, S.M.6
  • 92
    • 84947087440 scopus 로고    scopus 로고
    • Transfusion management of patients receiving daratumumab therapy for advanced plasma cell myeloma
    • Hannon JL, Clarke G. Transfusion management of patients receiving daratumumab therapy for advanced plasma cell myeloma. Transfusion. 2015;55(11):2770.
    • (2015) Transfusion , vol.55 , Issue.11 , pp. 2770
    • Hannon, J.L.1    Clarke, G.2
  • 93
    • 84979658583 scopus 로고    scopus 로고
    • Interference of new drugs with compatibility testing for blood transfusion
    • Murphy MF, Dumont LJ, Greinacher A; BEST Collaborative. Interference of new drugs with compatibility testing for blood transfusion. N Engl J Med. 2016;375(3):295-296.
    • (2016) N Engl J Med. , vol.375 , Issue.3 , pp. 295-296
    • Murphy, M.F.1    Dumont, L.J.2    Greinacher, A.3
  • 94
    • 85007087410 scopus 로고    scopus 로고
    • Daratumumab and blood-compatibility testing
    • Dimopoulos MA, Sonneveld P, Sun H. Daratumumab and blood-compatibility testing. N Engl J Med. 2016;375(25):2497-2498.
    • (2016) N Engl J Med. , vol.375 , Issue.25 , pp. 2497-2498
    • Dimopoulos, M.A.1    Sonneveld, P.2    Sun, H.3
  • 95
    • 85020060451 scopus 로고    scopus 로고
    • Outcomes and management of red blood cell transfusions in multiple myeloma patients treated with daratumumab [abstract]
    • Abstract 3571
    • Chari A, Satta T, Tayal A, et al. Outcomes and management of red blood cell transfusions in multiple myeloma patients treated with daratumumab [abstract]. Blood. 2015; 126(23). Abstract 3571.
    • (2015) Blood , vol.126 , Issue.23
    • Chari, A.1    Satta, T.2    Tayal, A.3
  • 96
    • 84991646684 scopus 로고    scopus 로고
    • First report of safety and efficacy of daratumumab in 2 cases of advanced immunoglobulin light chain amyloidosis
    • Sher T, Fenton B, Akhtar A, Gertz MA. First report of safety and efficacy of daratumumab in 2 cases of advanced immunoglobulin light chain amyloidosis. Blood. 2016;128(15): 1987-1989.
    • (2016) Blood , vol.128 , Issue.15 , pp. 1987-1989
    • Sher, T.1    Fenton, B.2    Akhtar, A.3    Gertz, M.A.4
  • 97
    • 85022168653 scopus 로고    scopus 로고
    • Hematologic responses and cardiac organ improvement in patients with heavily pretreated cardiac immunoglobulin light chain (AL) amyloidosis receiving daratumumab [abstract]
    • Abstract 4525
    • Kaufman G, Witteles R, Wheeler M, et al. Hematologic responses and cardiac organ improvement in patients with heavily pretreated cardiac immunoglobulin light chain (AL) amyloidosis receiving daratumumab [abstract]. Blood. 2016;128(22). Abstract 4525.
    • (2016) Blood , vol.128 , Issue.22
    • Kaufman, G.1    Witteles, R.2    Wheeler, M.3
  • 98
    • 85016153596 scopus 로고    scopus 로고
    • The human CD38 monoclonal antibody daratumumab shows antitumor activity and hampers leukemia-microenvironment interactions in chronic lymphocytic leukemia
    • Matas-Céspedes A, Vidal-Crespo A, Rodriguez V, et al. The human CD38 monoclonal antibody daratumumab shows antitumor activity and hampers leukemia-microenvironment interactions in chronic lymphocytic leukemia. Clin Cancer Res. 2017;23(6):1493-1505.
    • (2017) Clin Cancer Res. , vol.23 , Issue.6 , pp. 1493-1505
    • Matas-Céspedes, A.1    Vidal-Crespo, A.2    Rodriguez, V.3
  • 99
    • 84991282075 scopus 로고    scopus 로고
    • Targeting CD38 in refractory extranodal natural killer cell-T-cell lymphoma
    • Hari P, Raj RV, Olteanu H. Targeting CD38 in refractory extranodal natural killer cell-T-cell lymphoma. N Engl J Med. 2016;375(15): 1501-1502.
    • (2016) N Engl J Med. , vol.375 , Issue.15 , pp. 1501-1502
    • Hari, P.1    Raj, R.V.2    Olteanu, H.3
  • 100
    • 85055847395 scopus 로고    scopus 로고
    • Drug resistance alters CD38 expression and in vitro response to daratumumab in waldenstrom macroglobulinemia cells [abstract]
    • Abstract 3018
    • Paulus A, Akhtar S, Bashir Y, et al. Drug resistance alters CD38 expression and in vitro response to daratumumab in waldenstrom macroglobulinemia cells [abstract]. Blood. 2016;128(22). Abstract 3018.
    • (2016) Blood , vol.128 , Issue.22
    • Paulus, A.1    Akhtar, S.2    Bashir, Y.3
  • 101
    • 84929958145 scopus 로고    scopus 로고
    • Anti-leukemic activity of daratumumab in acute myeloid leukemia cells and patientderived xenografts [abstract]
    • Abstract 2312
    • Dos Santos C, Xiaochuan S, Chenghui Z, et al. Anti-leukemic activity of daratumumab in acute myeloid leukemia cells and patientderived xenografts [abstract]. Blood. 2014; 124(21). Abstract 2312.
    • (2014) Blood , vol.124 , Issue.21
    • Dos Santos, C.1    Xiaochuan, S.2    Chenghui, Z.3
  • 102
    • 85045627808 scopus 로고    scopus 로고
    • Daratumumab is effective in the treatment of refractory post-transplant autoimmune hemolytic anemia: A pediatric case report [abstract]
    • Abstract 4819
    • Tolbert V, Goldsby R, Huang J, et al. Daratumumab is effective in the treatment of refractory post-transplant autoimmune hemolytic anemia: a pediatric case report [abstract]. Blood. 2016;128(22). Abstract 4819.
    • (2016) Blood , vol.128 , Issue.22
    • Tolbert, V.1    Goldsby, R.2    Huang, J.3
  • 104
    • 85017665989 scopus 로고    scopus 로고
    • Systematic literature review and network meta-analysis of treatment outcomes in relapsed and/or refractory multiple myeloma
    • van Beurden-Tan CHY, Franken MG, Blommestein HM, Uyl-de Groot CA, Sonneveld P. Systematic literature review and network meta-analysis of treatment outcomes in relapsed and/or refractory multiple myeloma. J Clin Oncol. 2017; 35(12):1312-1319.
    • (2017) J Clin Oncol. , vol.35 , Issue.12 , pp. 1312-1319
    • Van Beurden-Tan, C.H.Y.1    Franken, M.G.2    Blommestein, H.M.3    Uyl-De Groot, C.A.4    Sonneveld, P.5
  • 105
    • 84930333012 scopus 로고    scopus 로고
    • An open-label, multicenter, phase 1b study of daratumumab in combination with backbone regimens in patients with multiple myeloma [abstract]
    • Abstract 176
    • Moreau P, Mateos MV, Bladé J, et al. An open-label, multicenter, phase 1b study of daratumumab in combination with backbone regimens in patients with multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 176.
    • (2014) Blood , vol.124 , Issue.21
    • Moreau, P.1    Mateos, M.V.2    Bladé, J.3
  • 106
    • 85054893374 scopus 로고    scopus 로고
    • Preliminary results from a phase Ib study of isatuximab in combination with pomalidomide (Pom) and dexamethasone (Dex) in relapsed and refractory multiple myeloma (RRMM)
    • Richardson P, Mikhael J, Usmani S, et al. Preliminary results from a phase Ib study of isatuximab in combination with pomalidomide (Pom) and dexamethasone (Dex) in relapsed and refractory multiple myeloma (RRMM). Clin Lymphoma Myeloma Leuk. 2017;17(suppl 1):e16-e17.
    • (2017) Clin Lymphoma Myeloma Leuk. , vol.17 , pp. e16-e17
    • Richardson, P.1    Mikhael, J.2    Usmani, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.