Gender disparity in pediatrics: A review of the current literature

Italian Journal of Pediatrics

Volumn 44, Issue 1, 2018, Pages

  Piccini, Paola ^a   Montagnani, Carlotta ^a   De Martino, Maurizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Children; Gender; Pediatrics

Indexed keywords

MEASLES VACCINE;

AGE DISTRIBUTION; BODY MASS; ERYTHROCYTE SEDIMENTATION RATE; GESTATIONAL AGE; HEALTH CARE POLICY; HEALTH CARE SYSTEM; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MEASLES; MORTALITY; NEUTROPHIL COUNT; PEDIATRICS; REVIEW; RISK FACTOR; SEX DIFFERENCE; WAIST CIRCUMFERENCE; CHILD; CHRONIC DISEASE; FEMALE; HEALTH CARE DISPARITY; HEALTH DISPARITY; MALE; NEEDS ASSESSMENT; PRESCHOOL CHILD; PROCEDURES; SEXISM; STATISTICS AND NUMERICAL DATA;

CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; FEMALE; HEALTH STATUS DISPARITIES; HEALTHCARE DISPARITIES; HUMANS; MALE; NEEDS ASSESSMENT; PEDIATRICS; SEXISM;

EID: 85039863802     PISSN: 17208424     EISSN: 18247288     Source Type: Journal    
DOI: 10.1186/s13052-017-0437-x     Document Type: Review

References (52)

1. Khera R, Jain S, Lodha R, Ramakrishnan S. Gender bias in child care and child health: global patterns. Arch Dis Child. 2014;99:369-74.
2. Festini F, Taccetti G, Repetto T, Cioni ML, de Martino M. Sex ratio at birth among Chinese babies born in Italy is lower than in China. J Epidemiol Community Health. 2003;57:967-8.
3. Festini F, de Martino M. Twenty five years of the one child family policy in China. J Epidemiol Community Health. 2004;58:358-60.
4. Singh PK. Trends in child immunization across geographical regions in India: focus on urban-rural and gender differentials. PLoS One. 2013;8:e73102.
5. Leiter V, Rieker PP. Mind the gap: gender differences in child special health care needs. Matern Child Health J. 2012;16:1072-80.
6. Esteban E, Bujaldon E, Esparza M, Jordan I, Esteban ME. Sex differences in children with severe health conditions: causes of admission and mortality in a pediatric intensive care unit. Am J Hum Biol. 2015;27:613-9.
7. Arsenault C, Harper S, Nandi A, Mendoza Rodríguez JM, Hansen PM, Johri M. Monitoring equity in vaccination coverage: a systematic analysis of demographic and health surveys from 45 Gavi-supported countries. Vaccine. 2017;35:951-9.
8. Song Y, Wang HJ, Ma J, Lau PW, Hu P, Zhang B, Wang Z. BMI-for-age Z-score distribution shifts among Chinese children: gender disparity. Obesity. 2014;22:1187-93.
9. van Vliet JS, Gustafsson PA, Duchen K, Nelson N. Social inequality and age-specific gender differences in overweight and perception of overweight among Swedish children and adolescents: a cross-sectional study. BMC Public Health. 2015;15:628.
10. Munakata H, Sei M, Ewis AA, Umeno M, Sato Y, Nakano T, et al. Prediction of Japanese children at risk for complications of childhood obesity: gender differences for intervention approaches. J Med Investig. 2010;57:62-8.
11. Lee M, Choi S, Lee Y, Oh HH. The gender association of the SIRT1 rs7895833 polymorphism with pediatric obesity: a 3-year panel study. J Nutrigenet Nutrigenomics. 2017;9:265-75.
12. Tester J, Sharma S, Jasik CB, Mietus-Snyder M, Tinajero-Deck L. Gender differences in prediabetes and insulin resistance among 1356 obese children in northern California. Diabetes MetabSyndr. 2013;7:161-5.
13. Samuelsson U, Lindblad B, Carlsson A, Forsander G, Ivarsson S, Kockum I, et al. Better diabetes diagnosis study group. Residual beta cell function at diagnosis of type 1 diabetes in children and adolescents varies with gender and season. Diabetes Metab Res Rev. 2013;29:85-9.
14. Sävendahl L, Blankenstein O, Oliver I, Christesen HT, Lee P, Pedersen BT, et al. Gender influences short-term growth hormone treatment response in children. Horm Res Paediatr. 2012;77:188-94.
15. van der Voorn B, Hollanders JJ, Ket JCF, Rotteveel J, Finke MJJ. Gender-specific differences in hypothalamus-pituitary-adrenal axis activity during childhood: a systematic review and meta-analysis. Biol Sex Differ. 2017;8:3.
16. Deslauriers JR, Lenz AM, Root AW, Diamond FB, Bercu BB. Gender related differences in glucocorticoid therapy and growth outcomes among pubertal children with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH). J Pediatr Endocrinol Metab. 2012;25:977-81.
17. Wasniewska M, Arrigo T, Crisafulli G, Aversa T, Messina MF, Salzano G, De Luca F. In the Italian population sexual dimorphism affects pre-natal thyroid migration but not biochemical severity of gland ectopia and pre-natal bone maturation. J Endocrinol Investig. 2008;31:341-5.
18. Ruggeri RM, Trimarchi F, Giuffrida G, Certo R, Cama E, Campennì A, Alibrandi A, De Luca F, Wasniewska M. Autoimmune comorbidities in Hashimoto's thyroiditis: different patterns of association in adulthood and childhood/adolescence. Eur J Endocrinol. 2017;176:133-41.
19. Reinhardt VP, Wetherby AM, Schatschneider C, Lord C. Examination of sex differences in a large sample of young children with autism spectrum disorder and typical development. J Autism Dev Disord. 2015;45:697-706.
20. May T, Cornish K, Rinehart N. Does gender matter? A one year follow-up of autistic, attention and anxiety symptoms in high-functioning children with autism spectrum disorder. J Autism Dev Disord. 2014;44:1077-86.
21. Say GN, Taşdemir HA, İnce H. Semiological and psychiatric characteristics of children with psychogenic nonepileptic seizures: gender-related differences. Seizure. 2015;31:144-8.
22. Tanidir C, Adaletli H, Gunes H, Kilicoglu AG, Mutlu C, Bahali MK, et al. Impact of gender, age at onset, and lifetime tic disorders on the clinical presentation and comorbidity pattern of obsessive-compulsive disorder in children and adolescents. J Child Adolesc Psychopharmacol. 2015;25:425-31.
23. Chaplin TM, Aldao A. Gender differences in emotion expression in children: a meta-analytic review. Psychol Bull. 2013;139:735-65.
24. Skiöld B, Alexandrou G, Padilla N, Blennow M, Vollmer B, Adén U. Sex differences in outcome and associations with neonatal brain morphology in extremely preterm children. J Pediatr. 2014;164:1012-8.
25. Llop S, Lopez-Espinosa MJ, Rebagliato M, Ballester F. Gender differences in the neurotoxicity of metals in children. Toxicology. 2013;311:3-12.
26. Salö M, Ohlsson B, Arnbjörnsson E, Stenström P. Appendicitis in children from a gender perspective. Pediatr Surg Int. 2015;31:845-53.
27. Thayu M, Shults J, Burnham JM, Zemel BS, Baldassano RN, Leonard MB. Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's disease. Inflamm Bowel Dis. 2007;13:1121-8.
28. Yik YI, Farmer PJ, King SK, Chow CW, Hutson JM, Southwell BR. Gender differences in reduced substance P (SP) in children with slow-transit constipation. Pediatr Surg Int. 2011;27:699-704.
29. Galli L, Puliti D, Chiappini E, Gabiano C, Tovo PA, Pezzotti P, de Martino M. Writing Commitee. Lower mother-to-child HIV-1 transmission in boys is independent of type of delivery and antiretroviral prophylaxis: the Italian register for HIV infection in children. J Acquir Immune Defic Syndr. 2005;40:479-85.
30. Condo JU, Gage A, Mock N, Rice J, Greiner T. Sex differences in nutritional status of HIV-exposed children in Rwanda: a longitudinal study. Tropical Med Int Health. 2015;20:17-23.
31. Shiau S, Kuhn L, Strehlau R, Martens L, McIlleron H, Meredith S, Wiesner L, Coovadia A, Abrams EJ, Arpadi SM. Sex differences in responses to antiretroviral treatment in south African HIV-infected children on ritonavir-boosted lopinavir- and nevirapine-based treatment. BMC Pediatr. 2014;14:39. https://doi.org/10.1186/1471-2431-14-39.
32. Sherr L, Mueller J, Varrall R. Evidence-based gender findings for children affected by HIV and AIDS - a systematic overview. AIDS Care. 2009;21:83-97.
33. Ghuman AK, Newth CJ, Khemani RG. Impact of gender on sepsis mortality and severity of illness for prepubertal and postpubertal children. J Pediatr. 2013;163:835-40.
34. Casimir GJ, Mulier S, Hanssens L, Zylberberg K, Duchateau J. Gender differences in inflammatory markers in children. Shock. 2010;33:258-62.
35. Stival A, Chiappini E, Montagnani C, Orlandini E, Buzzoni C, Galli L, de Martino M. Sexual dimorphism in tuberculosis incidence: children cases compared to adult cases in Tuscany from 1997 to 2011. PLoS One. 2014;9:e105277.
36. de St Maurice A, Schaffner W, Griffin MR, Griffin MR, Halasa N, Grijalva CG. Persistent sex disparities in invasive pneumococcal diseases in the conjugate vaccine era. J Infect Dis. 2016;214:792-7.
37. Voysey M, Pollard AJ, Perera R, Fanshawe TR. Assessing sex-differences and the effect of timing of vaccination on immunogenicity, reactogenicity and efficacy of vaccines in young children: study protocol for an individual participant data meta-analysis of randomized controlled trials. BMJ Open. 2016;6:e011680.
38. Projecto de Saúde de Bandim, Indepth Network, Bissau, Guinea-Bissau, Aaby P, Garly ML, Nielsen J, Ravn H, Martins C, Balé C, et al. Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: Observations from vaccination trials in Guinea-Bissau. Pediatr Infect Dis J. 2007;26:247-52.
39. Aaby P, Nielsen J, Benn CS, Trape JF. Sex-differential effects on mortality of BCG and diphtheria-tetanus-pertussis vaccines in a rural area with high vaccination coverage: observational study from Senegal. Trans R Soc Trop Med Hyg. 2016;110:527-33.
40. Curran EK, Sainani KL, Le GM, Propp JM, Fisher PG. Gender affects survival for medulloblastoma only in older children and adults: a study from the surveillance epidemiology and end results registry. Pediatr Blood Cancer. 2009;52:60-4.
41. Meeske KA, Ji L, Freyer DR, Gaynon P, Ruccione K, Butturini A, et al. Comparative toxicity by sex among children treated for acute lymphoblastic leukemia: a report from the Children's oncology group. Pediatr Blood Cancer. 2015;62:2140-9.
42. Al-Mayouf SM, Al Sonbul A. Influence of gender and age of onset on the outcome in children with systemic lupus erythematosus. Clin Rheumatol. 2008;27:1159-62.
43. Zein JG, Udeh BL, Gerald Teague W, Koroukian SM, Schlitz NK, Bleecker ER, Busse WB, Calhoun WJ, Castro M, Comhair SA, Fitzpatrick AM, Israel E, Wenzel SE, Holguin F, Gaston BM, Erzurum SC, The severe asthma research program. Impact of age and sex on outcomes and hospital cost of acute asthma in the United States, 2011-2012. PLoS One. 2016;11:e0157301.
44. Jang Y, Shin A. Sex-based differences in asthma among preschool and school-aged children in Korea. PLoS One. 2015;10:e0140057.
45. Willeboordse M, van den Bersselaar DL, van de Kant KD, Muris JW, van Schayck OC, Dompeling E. Sex differences in the relationship between asthma and overweight in Dutch children: a survey study. PLoS One. 2013;8:e77574.
46. Lang JE, Holbrook JT, Wise RA, Dixon AE, Teague WG, Wei CY, et al. Obesity in children with poorly controlled asthma: sex differences. Pediatr Pulmonol. 2013;48:847-56.
47. Plevkova J, Buday T, Kavalcikova-Bogdanova N, Ioan I, Demoulin-Alexikova S. Sex differences in cough reflex. Respir Physiol Neurobiol. 2016; https://doi.org/10.1016/j.resp.2016.12.001.
48. Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain. 2009;10:447-85.
49. Racine M, Tousignant-Laflamme Y, Kloda LA, Dion D, Dupuis G, Choinière MA. Systematic literature review of 10 years of research on sex/gender and pain perception - part 2: do biopsychosocial factors alter pain sensitivity differently in women and men? Pain. 2012;153:619-35.
50. Kroner-Herwig B, Heinrich M, Morris L. Headache in German children and adolescents: a population-based epidemiological study. Cephalalgia. 2007;27:519-27.
51. Brun Sundblad GM, Saartok T, Engstrom LM. Prevalence and co-occurrence of self-rated pain and perceived health in school-children: age and gender differences. Eur J Pain. 2007;11:171-80.
52. Boerner KE, Eccleston C, Chambers CT, Keogh E. Sex differences in the efficacy of psychological therapies for the management of chronic and recurrent pain in children and adolescents: a systematic review and meta-analysis. Pain. 2017;158:569-82.