Investigation of nepetolide as a novel lead compound: Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking evaluation

Saudi Pharmaceutical Journal

Volumn 26, Issue 3, 2018, Pages 422-429

  ur Rehman, Tanzeel ^a   Khan, Arif ullah ^a   Abbas, Azar ^a   Hussain, Javid ^b   Khan, Farman Ullah ^c   Stieglitz, Kimberly ^d   Ali, Shamsher ^e  

^a RIPHAH INTERNATIONAL UNIVERSITY   (Pakistan)

^b UNIVERSITY OF NIZWA   (Oman)

^c Department of ChemistryUniversity of Science and Technology ^*  (Pakistan)

^d STEM Biotechnology DivisionRoxbury Community College   (United States)

^e NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Analgesic; Anti inflammatory; Anticancer; Antimicrobial; Antioxidant; Computational Pharmacology; Cytotoxic; Nepetolide

Indexed keywords

ACETIC ACID; ACETYLSALICYLIC ACID; ARACHIDONATE 15 LIPOXYGENASE; ASCORBIC ACID; CIPROFLOXACIN; CYCLOOXYGENASE 2; DICLOFENAC; DITERPENE; EPIDERMAL GROWTH FACTOR RECEPTOR; ETOPOSIDE; INDOMETACIN; NEPETOLIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VINCRISTINE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTEMIA; ARTICLE; ASPERGILLUS NIGER; CANCER INHIBITION; CANDIDA ALBICANS; CARRAGEENAN-INDUCED INFLAMMATION; CARRAGEENAN-INDUCED PAW EDEMA; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; LC50; LETHALITY; MALE; MOLECULAR DOCKING; NEPETA; NONHUMAN; RAT; STAPHYLOCOCCUS AUREUS; WRITHING TEST;

EID: 85039851851     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2017.12.019     Document Type: Article

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