Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains

DMM Disease Models and Mechanisms

Volumn 10, Issue 12, 2017, Pages 1489-1502

  Li, Weizhe ^a   Gorantla, Santhi ^a   Gendelman, Howard E ^a   Poluektova, Larisa Y ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Astrocytes; Hematopoietic stem progenitor cells; HIV 1; Humanized mice; Neuronal progenitors

Indexed keywords

CELL MARKER; INTERFERON REGULATORY FACTOR 9; MAG PROTEIN; MBP PROTEIN; MOBP PROTEIN; MYELIN; PLP1 PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BST2; TRANSCRIPTION FACTOR IFI6; TRANSCRIPTION FACTOR ISG15; TRANSCRIPTION FACTOR MX1; TRANSCRIPTION FACTOR OAS1; TRANSCRIPTION FACTOR RSAD2; TRANSCRIPTION FACTOR SAMHD1; UNCLASSIFIED DRUG; ZNF488 PROTEIN; INTERFERON; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN STEM; CELL INFILTRATION; CONTROLLED STUDY; CORPUS CALLOSUM; CYTOSKELETON; DOWN REGULATION; FEMALE; GLIA CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; IMMUNE SYSTEM; INTRACELLULAR SIGNALING; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL TRANSPLANTATION; NEWBORN; NOD SCID GAMMA MOUSE; NONHUMAN; OLFACTORY BULB; OLIGODENDROGLIA; PRIORITY JOURNAL; RNA SEQUENCE; SYSTEMIC DISEASE; VIRUS CELL INTERACTION; WHITE MATTER; ANIMAL; BLOOD; BRAIN; CELL COMMUNICATION; COCULTURE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GLIA; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOID TISSUE; MACROPHAGE; METABOLISM; NEURAL STEM CELL; PATHOLOGY; REPRODUCIBILITY; SPECIES DIFFERENCE; TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BRAIN; CELL COMMUNICATION; COCULTURE TECHNIQUES; GENE EXPRESSION REGULATION; HIV INFECTIONS; HUMANS; INTERFERON TYPE I; LYMPHOID TISSUE; MACROPHAGES; MICE; NEURAL STEM CELLS; NEUROGLIA; REPRODUCIBILITY OF RESULTS; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 85039767989     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.031773     Document Type: Article

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